Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26 S proteasome in fission yeast

Journal of Molecular Biology

Volumn 344, Issue 3, 2004, Pages 697-706

  Stone, Miranda ^a   Hartmann Petersen, Rasmus ^a   Seeger, Michael ^b   Bech Otschir, Dawadschargal ^a   Wallace, Mairi ^a   Gordon, Colin ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

hydrolase; proteasome; ubiquitin; UBP UCH

Indexed keywords

CALVASCULIN; FUNGAL PROTEIN; PROTEASOME; PROTEIN MTS2; PROTEIN MTS3; PROTEIN RPN12; PROTEIN RPN9; PROTEIN RPT2; PROTEIN SUBUNIT; PROTEIN UBP6; PROTEIN UCH2; PROTEIN UCH37; PROTEIN USP14; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCHIZOSACCHAROMYCES POMBE; UBIQUITINATION; YEAST;

SCHIZOSACCHAROMYCES POMBE;

EID: 7944230364     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.09.057     Document Type: Article

References (41)

1. M.H. Glickman, and A. Ciechanover The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol. Rev. 82 2002 373 428
2. C.M. Pickart Mechanisms underlying ubiquitination Annu. Rev. Biochem. 70 2001 503 533
3. J.S. Thrower, L. Hoffman, M. Rechsteiner, and C.M. Pickart Recognition of the polyubiquitin proteolytic signal EMBO J. 19 2000 94 102
4. D. Voges, P. Zwickl, and W. Baumeister The 26S proteasome: a molecular machine designed for controlled proteolysis Annu. Rev. Biochem. 68 1999 1015 1068
5. M. Groll, L. Ditzel, J. Löwe, D. Stock, M. Bochtler, H.D. Bartunik, and R. Huber Structure of 20S proteasome from yeast at 2.4 Å resolution Nature 386 1997 463 471
6. K.D. Wilkinson Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome Semin. Cell Dev. Biol. 11 2000 141 148
7. S.S. Wing Deubiquitinating enzymes - the importance of driving in reverse along the ubiquitin-proteasome pathway Int. J. Biochem. Cell Biol. 35 2003 590 605
8. F.R. Papa, A.Y. Amerik, and M. Hochstrasser Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome Mol. Biol. Cell 10 1999 741 756
9. Y.A. Lam, W. Xu, G.N. DeMartino, and R.E. Cohen Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome Nature 385 1997 737 740
10. R. Verma, L. Aravind, R. Oania, W.H. McDonald, J.R. Yates III, E.V. Koonin, and R.J. Deshaies Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome Science 298 2002 611 615
11. T. Yao, and R.E. Cohen A cryptic protease couples deubiquitination and degradation by the proteasome Nature 419 2002 403 407
12. A. Guterman, and M.H. Glickman Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome J. Biol. Chem. 279 2004 1729 1738
13. H. Hölzl, B. Kapelari, J. Kellermann, E. Seemüller, M. Sumegi, and A. Udvardy The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme J. Cell Biol. 150 2000 119 130
14. T. Li, N.I. Naqvi, H. Yang, and T.S. Teo Identification of a 26S proteasome-associated UCH in fission yeast Biochem. Biophys. Res. Commun. 272 2000 270 275
15. R. Verma, S. Chen, R. Feldman, D. Schieltz, J. Yates, J. Dohmen, and R.J. Deshaies Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes Mol. Biol. Cell 11 2000 3425 3439
16. A. Borodovsky, B.M. Kessler, R. Casagrande, H.S. Overkleeft, K.D. Wilkinson, and H.L. Ploegh A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14 EMBO J. 20 2001 5187 5196
17. D.S. Leggett, J. Hanna, A. Borodovsky, B. Crosas, M. Schmidt, and R.T. Baker Multiple associated proteins regulate proteasome structure and function Mol. Cell 10 2002 495 507
18. K.C. Park, S.K. Woo, Y.J. Yoo, A.M. Wyndham, R.T. Baker, and C.H. Chung Purification and characterization of UBP6, a new ubiquitin-specific protease in Saccharomyces cerevisiae Arch. Biochem. Biophys. 347 1997 78 84
19. A.Y. Amerik, J. Nowak, S. Swaminathan, and M. Hochstrasser The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways Mol. Biol. Cell 11 2000 3365 3380
20. S. Dupre, and R. Haguenauer-Tsapis Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase Mol. Cell. Biol. 21 2001 4482 4494
21. M. Seeger, R. Hartmann-Petersen, C.R. Wilkinson, M. Wallace, I. Samejima, M.S. Taylor, and C. Gordon Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins J. Biol. Chem. 278 2003 16791 16796
22. S. Elsasser, D. Chandler-Militello, B. Müller, J. Hanna, and D. Finley Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome J. Biol. Chem. 279 2004 26817 26822
23. C.R. Wilkinson, M. Wallace, M. Morphew, P. Perry, R. Allshire, and J.P. Javerzat Localization of the 26S proteasome during mitosis and meiosis in fission yeast EMBO J. 17 1998 6465 6476
24. C. Gordon, G. McGurk, P. Dillon, C. Rosen, and N. Hastie Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit Nature 366 1993 355 357
25. R. Hartmann-Petersen, and C. Gordon Integral UBL domain proteins: a family of proteasome interacting proteins Semin. Cell Dev. Biol. 15 2004 247 259
26. T. Li, W. Duan, H. Yang, M.K. Lee, F. Bte Mustafa, B.H. Lee, and T.S. Teo Identification of two proteins, S14 and UIP1, that interact with UCH37 FEBS Letters 488 2001 201 205
27. M.H. Glickman, D.M. Rubin, O. Coux, I. Wefes, G. Pfeifer, and Z. Cjeka A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3 Cell 94 1998 615 623
28. K.B. Hendil The 19 S multicatalytic "prosome" proteinase is a constitutive enzyme in HeLa cells Biochem. Int. 17 1988 471 477
29. S. Elsasser, R.R. Gali, M. Schwickart, C.N. Larsen, D.S. Leggett, and B. Müller Proteasome subunit Rpn1 binds ubiquitin-like protein domains Nature Cell Biol. 4 2002 725 730
30. S.M. Wilson, B. Bhattacharyya, R.A. Rachel, V. Coppola, L. Tessarollo, and D.B. Householder Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease Nature Genet. 32 2002 420 425
31. T.A. Chernova, K.D. Allen, L.M. Wesoloski, J.R. Shanks, Y.O. Chernoff, and K.D. Wilkinson Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of the free ubiquitin pool J. Biol. Chem. 278 2003 52102 52115
32. A.Y. Amerik, S.J. Li, and M. Hochstrasser Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae Biol. Chem. 381 2000 981 992
33. J. Hanna, D.S. Leggett, and D. Finley Ubiquitin depletion as a key mediator of toxicity by translational inhibitors Mol. Cell. Biol. 23 2003 9251 9261
34. S. Swaminathan, A.Y. Amerik, and M. Hochstrasser The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast Mol. Biol. Cell 10 1999 2583 2594
35. M. Cohen, F. Stutz, N. Belgareh, R. Haguenauer-Tsapis, and C. Dargemont Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23 Nature Cell Biol. 5 2003 661 667
36. + is defective in metaphase to anaphase transition J. Biol. Chem. 271 1996 5704 5711
37. C.R. Wilkinson, M. Wallace, M. Seeger, W. Dubiel, and C. Gordon Mts4, a non-ATPase subunit of the 26 S protease in fission yeast is essential for mitosis and interacts directly with the ATPase subunit Mts2 J. Biol. Chem. 272 1997 25768 25777
38. + gene encodes a subunit of the 26 S proteasome in fission yeast J. Biol. Chem. 273 1998 23938 23945
39. C.R. Wilkinson, K. Ferrell, M. Penney, M. Wallace, W. Dubiel, and C. Gordon Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised J. Biol. Chem. 275 2000 15182 15192
40. S. Moreno, A. Klar, and P. Nurse Molecular genetic analysis of fission yeast Schizosaccharomyces pombe Methods Enzymol. 194 1991 795 823
41. J. Bähler, J.Q. Wu, M.S. Longtine, N.G. Shah, A. McKenzie III, and A.B. Steever Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe Yeast 14 1998 943 951