Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia

International Journal of Oncology

Volumn 29, Issue 4, 2006, Pages 1025-1033

  Ihnatko, Robert ^a   Kubes, Miroslav ^a   Takacova, Martina ^a   Sedlakova, Olga ^a   Sedlak, Jan ^b   Pastorek, Jaromir ^a   Kopacek, Juraj ^a   Pastorekova, Silvia ^a  

^a INSTITUTE OF VIROLOGY   (Slovakia)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Acidosis; Carbonic anhydrase IX; Hypoxia; Promoter; Transcriptional regulation; Tumor microenvironment

Indexed keywords

CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR ANTIGEN;

ACIDOSIS; ARTICLE; CELL HYPOXIA; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM TUMOR; DRUG ANTAGONISM; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETICS; GLIOBLASTOMA; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROMOTER REGION; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACIDOSIS; ANTIGENS, NEOPLASM; CARBONIC ANHYDRASES; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM NEOPLASMS; GLIOBLASTOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC;

EID: 33846562017     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.29.4.1025     Document Type: Article

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