Novel cyclopentadienyl tricarbonyl complexes of 99mTc mimicking chalcone as potential single-photon emission computed tomography imaging probes for β-amyloid plaques in brain

Journal of Medicinal Chemistry

Volumn 56, Issue 2, 2013, Pages 471-482

  Li, Zijing ^a   Cui, Mengchao ^a   Dai, Jiapei ^b   Wang, Xuedan ^a   Yu, Pingrong ^a   Yang, Yanping ^a   Jia, Jianhua ^a   Fu, Hualong ^a   Ono, Masahiro ^c   Jia, Hongmei ^a   Saji, Hideo ^c   Liu, Boli ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 [1 OXO 3 (4 DIMETHYLAMINOPHENYL) 2 PROPENYL](CYCLOPENTADIENYL)TRICARBONYLRHENIUM TC 99M; 1 [1 OXO 5 (4 DIMETHYLAMINOPHENYL) 2,4 PENTADIENYL](CYCLOPENTADIENYL)TRICARBONYLRHENIUM TC 99M; 1 [1 OXO 7 (4 DIMETHYLAMINOPHENYL) 2,4,6 HEPTATRIENYL)](CYCLOPENTADIENYL)TRICARBONYLRHENIUM TC 99M; AMYLOID BETA PROTEIN; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING ASSAY; BRAIN; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG PENETRATION; HEART; IN VITRO STUDY; KIDNEY; LUNG; MALE; MOUSE; NONHUMAN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SMALL INTESTINE; SPLEEN; STOMACH; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; ANIMALS; AUTORADIOGRAPHY; BRAIN; CHALCONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; ORGANOTECHNETIUM COMPOUNDS; POSITRON-EMISSION TOMOGRAPHY;

EID: 84872785684     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3014184     Document Type: Article

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