Synthesis and biological evaluation of 99mTc, Re-monoamine-monoamide conjugated to 2-(4-aminophenyl)benzothiazole as potential probes for β-amyloid plaques in the brain

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 4, 2008, Pages 1442-1445

  Chen, Xiangji ^a   Yu, Pingrong ^a   Zhang, Lianfeng ^b   Liu, Boli ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b INSTITUTE OF LABORATORY ANIMAL SCIENCE   (China)

Author keywords

Amyloid; 2 (4 Aminophenyl)benzothiazole; Technetium 99m

Indexed keywords

AMYLOID BETA PROTEIN; BENZOTHIAZOLE ANILINE MONOAMINE MONOAMIDE TC 99M; RADIOPHARMACEUTICAL AGENT; RHENIUM COMPLEX; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN TISSUE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; FLUORESCENCE ANALYSIS; HUMAN; HUMAN TISSUE; NONHUMAN; SENILE PLAQUE;

ALZHEIMER DISEASE; AMIDES; AMINES; AMYLOID BETA-PROTEIN; ANIMALS; BENZOTHIAZOLES; BLOOD-BRAIN BARRIER; BRAIN; HUMANS; ISOTOPE LABELING; MALE; MICE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; RHENIUM; TECHNETIUM COMPOUNDS; TISSUE DISTRIBUTION;

EID: 39049171418     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.071     Document Type: Article

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