Ubiquitin-dependent regulation of phospho-AKT Dynamics by the ubiquitin E3 LIGASE, NEDD4-1, in the insulin-like growth factor-1 response

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1674-1684

  Fan, Chuan Dong ^a   Lum, Michelle A ^a,b   Xu, Chao ^a   Black, Jennifer D ^a   Wang, Xinjiang ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AKT ACTIVATION; CELLULAR PROCESS; CHAIN FORMATION; E3 LIGASE; IN-VITRO; IN-VIVO; INSULIN-LIKE GROWTH FACTOR; INSULIN-LIKE GROWTH FACTOR-1; LIGASES; MEMBRANE BINDING; PERINUCLEAR REGION; POLYUBIQUITIN; PROTEASOMAL DEGRADATION; SUBCELLULAR LOCALIZATIONS; UBIQUITIN; UBIQUITINATION;

ACTIVATION ANALYSIS; CELL MEMBRANES; CYTOLOGY; DYNAMICS; ENZYMES; LIGANDS; PHOSPHORYLATION;

INSULIN;

PROTEASOME; PROTEIN KINASE B; SOMATOMEDIN C; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE NEDD4;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL FRACTIONATION; CELL MEMBRANE; CELL NUCLEUS; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOPLASM; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MEMBRANE BINDING; MOUSE; MUTANT; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION; WILD TYPE;

ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; CYTOPLASM; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICE; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84872736566     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.416339     Document Type: Article

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