The E3 Ligase TTC3 Facilitates Ubiquitination and Degradation of Phosphorylated Akt

Developmental Cell

Volumn 17, Issue 6, 2009, Pages 800-810

  Suizu, Futoshi ^a   Hiramuki, Yosuke ^a   Okumura, Fumihiko ^b   Matsuda, Mami ^a   Okumura, Akiko J ^a   Hirata, Noriyuki ^a   Narita, Masumi ^a   Kohno, Takashi ^d   Yokota, Jun ^d   Bohgaki, Miyuki ^b   Obuse, Chikashi ^a   Hatakeyama, Shigetsugu ^b   Obata, Toshiyuki ^c   Noguchi, Masayuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

CELLBIO; SIGNALING

Indexed keywords

PROTEASOME; PROTEIN KINASE B; SERINE; TETRATRICOPEPTIDE REPEAT DOMAIN 3 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL NUCLEUS; CHROMOSOME 21; CONTROLLED STUDY; DOWN SYNDROME; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; UBIQUITINATION;

CELL LINE; CELLS, CULTURED; DOWN SYNDROME; HUMANS; IMMUNOPRECIPITATION; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPPING; PROTO-ONCOGENE PROTEINS C-AKT; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 71649104466     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2009.09.007     Document Type: Article

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