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Volumn 12, Issue 1, 2013, Pages 39-46

Association study of 37 genes related to serotonin and dopamine neurotransmission and neurotrophic factors in cocaine dependence

Author keywords

5 HT2A; Addiction; Case control association study; Cocaine dependence; Dopamine; Genetics; HTR2A; Neurotransmission; Neurotrophic factors; Serotonin

Indexed keywords

DNA; DOPAMINE; NEUROTROPHIC FACTOR; SEROTONIN; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR HTR2A; UNCLASSIFIED DRUG;

EID: 84872687261     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/gbb.12013     Document Type: Article
Times cited : (22)

References (62)
  • 1
    • 35648931553 scopus 로고    scopus 로고
    • Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor
    • Angelucci, F., Ricci, V., Pomponi, M., Conte, G., Mathe, A.A., Attilio Tonali, P. & Bria, P. (2007) Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. J Psychopharmacol 21, 820-825.
    • (2007) J Psychopharmacol , vol.21 , pp. 820-825
    • Angelucci, F.1    Ricci, V.2    Pomponi, M.3    Conte, G.4    Mathe, A.A.5    Attilio Tonali, P.6    Bria, P.7
  • 2
    • 71749098763 scopus 로고    scopus 로고
    • Effects of psychostimulants on neurotrophins implications for psychostimulant-induced neurotoxicity
    • Angelucci, F., Ricci, V., Spalletta, G., Caltagirone, C., Mathe, A.A. & Bria, P. (2009) Effects of psychostimulants on neurotrophins implications for psychostimulant-induced neurotoxicity. Int Rev Neurobiol 88, 1-24.
    • (2009) Int Rev Neurobiol , vol.88 , pp. 1-24
    • Angelucci, F.1    Ricci, V.2    Spalletta, G.3    Caltagirone, C.4    Mathe, A.A.5    Bria, P.6
  • 3
    • 46649104724 scopus 로고    scopus 로고
    • Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats
    • Bahi, A., Boyer, F., Chandrasekar, V. & Dreyer, J.L. (2008) Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats. Psychopharmacology (Berl) 199, 169-182.
    • (2008) Psychopharmacology (Berl) , vol.199 , pp. 169-182
    • Bahi, A.1    Boyer, F.2    Chandrasekar, V.3    Dreyer, J.L.4
  • 4
    • 36749074966 scopus 로고    scopus 로고
    • Polymorphisms TaqI A of the DRD2, BalI of the DRD3, exon III repeat of the DRD4, and 3' UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents?
    • Ballon, N., Leroy, S., Roy, C., Bourdel, M.C., Olie, J.P., Charles-Nicolas, A., Krebs, M.O. & Poirier, M.F. (2007) Polymorphisms TaqI A of the DRD2, BalI of the DRD3, exon III repeat of the DRD4, and 3' UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents? Am J Med Genet B Neuropsychiatr Genet 144B, 1034-1041.
    • (2007) Am J Med Genet B Neuropsychiatr Genet , vol.144 B , pp. 1034-1041
    • Ballon, N.1    Leroy, S.2    Roy, C.3    Bourdel, M.C.4    Olie, J.P.5    Charles-Nicolas, A.6    Krebs, M.O.7    Poirier, M.F.8
  • 5
  • 7
    • 0035828110 scopus 로고    scopus 로고
    • Novel and previously reported single-nucleotide polymorphisms in the human 5-HT(1B) receptor gene: no association with cocaine or alcohol abuse or dependence
    • Cigler, T., LaForge, K.S., McHugh, P.F., Kapadia, S.U., Leal, S.M. & Kreek, M.J. (2001) Novel and previously reported single-nucleotide polymorphisms in the human 5-HT(1B) receptor gene: no association with cocaine or alcohol abuse or dependence. Am J Med Genet 105, 489-497.
    • (2001) Am J Med Genet , vol.105 , pp. 489-497
    • Cigler, T.1    LaForge, K.S.2    McHugh, P.F.3    Kapadia, S.U.4    Leal, S.M.5    Kreek, M.J.6
  • 9
    • 0033966753 scopus 로고    scopus 로고
    • A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia
    • Cubells, J.F., Kranzler, H.R., McCance-Katz, E., Anderson, G.M., Malison, R.T., Price, L.H. & Gelernter, J. (2000) A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia. Mol Psychiatry 5, 56-63.
    • (2000) Mol Psychiatry , vol.5 , pp. 56-63
    • Cubells, J.F.1    Kranzler, H.R.2    McCance-Katz, E.3    Anderson, G.M.4    Malison, R.T.5    Price, L.H.6    Gelernter, J.7
  • 11
    • 0037174807 scopus 로고    scopus 로고
    • 5-HT2 receptor antagonists given in the acute withdrawal from daily cocaine injections can reverse established sensitization
    • Davidson, C., Lazarus, C., Xiong, X., Lee, T.H. & Ellinwood, E.H. (2002) 5-HT2 receptor antagonists given in the acute withdrawal from daily cocaine injections can reverse established sensitization. Eur J Pharmacol 453, 255-263.
    • (2002) Eur J Pharmacol , vol.453 , pp. 255-263
    • Davidson, C.1    Lazarus, C.2    Xiong, X.3    Lee, T.H.4    Ellinwood, E.H.5
  • 12
    • 77749249653 scopus 로고    scopus 로고
    • Genome wide association for addiction: replicated results and comparisons of two analytic approaches
    • Drgon, T., Zhang, P.W., Johnson, C., Walther, D., Hess, J., Nino, M. & Uhl, G.R. (2010) Genome wide association for addiction: replicated results and comparisons of two analytic approaches. PLoS One 5, e8832.
    • (2010) PLoS One , vol.5
    • Drgon, T.1    Zhang, P.W.2    Johnson, C.3    Walther, D.4    Hess, J.5    Nino, M.6    Uhl, G.R.7
  • 13
    • 80054850501 scopus 로고    scopus 로고
    • Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence
    • Enoch, M.A., Gorodetsky, E., Hodgkinson, C., Roy, A. & Goldman, D. (2010) Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence. Mol Psychiatry 16, 1139-1146.
    • (2010) Mol Psychiatry , vol.16 , pp. 1139-1146
    • Enoch, M.A.1    Gorodetsky, E.2    Hodgkinson, C.3    Roy, A.4    Goldman, D.5
  • 14
    • 0035987117 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement
    • Fantegrossi, W.E., Ullrich, T., Rice, K.C., Woods, J.H. & Winger, G. (2002) 3, 4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement. Psychopharmacology (Berl) 161, 356-364.
    • (2002) Psychopharmacology (Berl) , vol.161 , pp. 356-364
    • Fantegrossi, W.E.1    Ullrich, T.2    Rice, K.C.3    Woods, J.H.4    Winger, G.5
  • 15
    • 78049527382 scopus 로고    scopus 로고
    • Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample
    • Fernandez-Castillo, N., Ribases, M., Roncero, C., Casas, M., Gonzalvo, B. & Cormand, B. (2010) Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample. Psychiatr Genet 20, 317-320.
    • (2010) Psychiatr Genet , vol.20 , pp. 317-320
    • Fernandez-Castillo, N.1    Ribases, M.2    Roncero, C.3    Casas, M.4    Gonzalvo, B.5    Cormand, B.6
  • 16
    • 18044377578 scopus 로고    scopus 로고
    • Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats
    • Filip, M. (2005) Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats. Pharmacol Rep 57, 35-46.
    • (2005) Pharmacol Rep , vol.57 , pp. 35-46
    • Filip, M.1
  • 17
    • 4243187058 scopus 로고    scopus 로고
    • Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses
    • Filip, M., Bubar, M.J. & Cunningham, K.A. (2004) Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. J Pharmacol Exp Ther 310, 1246-1254.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 1246-1254
    • Filip, M.1    Bubar, M.J.2    Cunningham, K.A.3
  • 18
    • 28344434009 scopus 로고    scopus 로고
    • Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats
    • Filip, M., Bubar, M.J. & Cunningham, K.A. (2006) Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats. Psychopharmacology (Berl) 183, 482-489.
    • (2006) Psychopharmacology (Berl) , vol.183 , pp. 482-489
    • Filip, M.1    Bubar, M.J.2    Cunningham, K.A.3
  • 19
    • 77953181780 scopus 로고    scopus 로고
    • Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction
    • Filip, M., Alenina, N., Bader, M. & Przegalinski, E. (2010) Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction. Addict Biol 15, 227-249.
    • (2010) Addict Biol , vol.15 , pp. 227-249
    • Filip, M.1    Alenina, N.2    Bader, M.3    Przegalinski, E.4
  • 20
    • 0036791976 scopus 로고    scopus 로고
    • Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding
    • Fletcher, P.J., Grottick, A.J. & Higgins, G.A. (2002) Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding. Neuropsychopharmacology 27, 576-586.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 576-586
    • Fletcher, P.J.1    Grottick, A.J.2    Higgins, G.A.3
  • 21
    • 0036837248 scopus 로고    scopus 로고
    • Neutralization of neutrophin-3 in the ventral tegmental area or nucleus accumbens differentially modulates cocaine-induced behavioral plasticity in rats
    • Freeman, A.Y. & Pierce, R.C. (2002) Neutralization of neutrophin-3 in the ventral tegmental area or nucleus accumbens differentially modulates cocaine-induced behavioral plasticity in rats. Synapse 46, 57-65.
    • (2002) Synapse , vol.46 , pp. 57-65
    • Freeman, A.Y.1    Pierce, R.C.2
  • 23
    • 0033068157 scopus 로고    scopus 로고
    • No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans
    • Gelernter, J., Kranzler, H. & Satel, S.L. (1999) No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans. Biol Psychiatry 45, 340-345.
    • (1999) Biol Psychiatry , vol.45 , pp. 340-345
    • Gelernter, J.1    Kranzler, H.2    Satel, S.L.3
  • 25
    • 85007320774 scopus 로고
    • FSTAT (version 1.2): a computer program to calculate F-statistics
    • Goudet, J. (1995) FSTAT (version 1.2): a computer program to calculate F-statistics. J Hered 86, 485-486.
    • (1995) J Hered , vol.86 , pp. 485-486
    • Goudet, J.1
  • 28
    • 79960817179 scopus 로고    scopus 로고
    • Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence
    • Johnson, C., Drgon, T., Walther, D. & Uhl, G.R. (2011) Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence. PLoS One 6, e19210.
    • (2011) PLoS One , vol.6
    • Johnson, C.1    Drgon, T.2    Walther, D.3    Uhl, G.R.4
  • 29
    • 0031719020 scopus 로고    scopus 로고
    • Cocaine use, abuse and dependence in a population-based sample of female twins
    • Kendler, K.S. & Prescott, C.A. (1998) Cocaine use, abuse and dependence in a population-based sample of female twins. Br J Psychiatry 173, 345-350.
    • (1998) Br J Psychiatry , vol.173 , pp. 345-350
    • Kendler, K.S.1    Prescott, C.A.2
  • 30
    • 0034012531 scopus 로고    scopus 로고
    • Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins
    • Kendler, K.S., Karkowski, L.M., Neale, M.C. & Prescott, C.A. (2000) Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins. Arch Gen Psychiatry 57, 261-269.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 261-269
    • Kendler, K.S.1    Karkowski, L.M.2    Neale, M.C.3    Prescott, C.A.4
  • 31
    • 0025855256 scopus 로고
    • The dopamine hypothesis of the reinforcing properties of cocaine
    • Kuhar, M.J., Ritz, M.C. & Boja, J.W. (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14, 299-302.
    • (1991) Trends Neurosci , vol.14 , pp. 299-302
    • Kuhar, M.J.1    Ritz, M.C.2    Boja, J.W.3
  • 32
    • 33845434956 scopus 로고    scopus 로고
    • Addiction molecular genetics: 639,401 SNP whole genome association identifies many "cell adhesion" genes
    • Liu, Q.R., Drgon, T., Johnson, C., Walther, D., Hess, J. & Uhl, G.R. (2006) Addiction molecular genetics: 639, 401 SNP whole genome association identifies many "cell adhesion" genes. Am J Med Genet B Neuropsychiatr Genet 141B, 918-925.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 B , pp. 918-925
    • Liu, Q.R.1    Drgon, T.2    Johnson, C.3    Walther, D.4    Hess, J.5    Uhl, G.R.6
  • 36
    • 24944549521 scopus 로고    scopus 로고
    • Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals
    • Mannelli, P., Patkar, A.A., Murray, H.W., Certa, K., Peindl, K., Mattila-Evenden, M. & Berrettini, W.H. (2005) Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals. Addict Biol 10, 261-268.
    • (2005) Addict Biol , vol.10 , pp. 261-268
    • Mannelli, P.1    Patkar, A.A.2    Murray, H.W.3    Certa, K.4    Peindl, K.5    Mattila-Evenden, M.6    Berrettini, W.H.7
  • 37
    • 75149198541 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and cocaine addiction
    • McGinty, J.F., Whitfield, T.W. Jr. & Berglind, W.J. (2010) Brain-derived neurotrophic factor and cocaine addiction. Brain Res 1314, 183-193.
    • (2010) Brain Res , vol.1314 , pp. 183-193
    • McGinty, J.F.1    Whitfield Jr., T.W.2    Berglind, W.J.3
  • 39
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller, S.A., Dykes, D.D. & Polesky, H.F. (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16, 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 40
    • 31844438317 scopus 로고    scopus 로고
    • Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine
    • Muller, C.P. & Huston, J.P. (2006) Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine. Trends Pharmacol Sci 27, 105-112.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 105-112
    • Muller, C.P.1    Huston, J.P.2
  • 41
    • 0033009323 scopus 로고    scopus 로고
    • Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence
    • Nakamura, T., Matsushita, S., Nishiguchi, N., Kimura, M., Yoshino, A. & Higuchi, S. (1999) Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence. Mol Psychiatry 4, 85-88.
    • (1999) Mol Psychiatry , vol.4 , pp. 85-88
    • Nakamura, T.1    Matsushita, S.2    Nishiguchi, N.3    Kimura, M.4    Yoshino, A.5    Higuchi, S.6
  • 42
    • 65349124145 scopus 로고    scopus 로고
    • Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model
    • Nic Dhonnchadha, B.A., Fox, R.G., Stutz, S.J., Rice, K.C. & Cunningham, K.A. (2009) Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behav Neurosci 123, 382-396.
    • (2009) Behav Neurosci , vol.123 , pp. 382-396
    • Nic Dhonnchadha, B.A.1    Fox, R.G.2    Stutz, S.J.3    Rice, K.C.4    Cunningham, K.A.5
  • 44
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt, D.R. (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74, 765-769.
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 45
    • 0034785673 scopus 로고    scopus 로고
    • Serotonin transporter (5-HTT) gene polymorphisms and susceptibility to cocaine dependence among African-American individuals
    • Patkar, A.A., Berrettini, W.H., Hoehe, M., Hill, K.P., Sterling, R.C., Gottheil, E. & Weinstein, S.P. (2001) Serotonin transporter (5-HTT) gene polymorphisms and susceptibility to cocaine dependence among African-American individuals. Addict Biol 6, 337-345.
    • (2001) Addict Biol , vol.6 , pp. 337-345
    • Patkar, A.A.1    Berrettini, W.H.2    Hoehe, M.3    Hill, K.P.4    Sterling, R.C.5    Gottheil, E.6    Weinstein, S.P.7
  • 46
    • 0036755405 scopus 로고    scopus 로고
    • No association between polymorphisms in the serotonin transporter gene and susceptibility to cocaine dependence among African-American individuals
    • Patkar, A.A., Berrettini, W.H., Hoehe, M., Hill, K.P., Gottheil, E., Thornton, C.C. & Weinstein, S.P. (2002) No association between polymorphisms in the serotonin transporter gene and susceptibility to cocaine dependence among African-American individuals. Psychiatr Genet 12, 161-164.
    • (2002) Psychiatr Genet , vol.12 , pp. 161-164
    • Patkar, A.A.1    Berrettini, W.H.2    Hoehe, M.3    Hill, K.P.4    Gottheil, E.5    Thornton, C.C.6    Weinstein, S.P.7
  • 47
    • 0033216135 scopus 로고    scopus 로고
    • Neurotrophin-3 contributes to the initiation of behavioral sensitization to cocaine by activating the Ras/Mitogen-activated protein kinase signal transduction cascade
    • Pierce, R.C., Pierce-Bancroft, A.F. & Prasad, B.M. (1999) Neurotrophin-3 contributes to the initiation of behavioral sensitization to cocaine by activating the Ras/Mitogen-activated protein kinase signal transduction cascade. J Neurosci 19, 8685-8695.
    • (1999) J Neurosci , vol.19 , pp. 8685-8695
    • Pierce, R.C.1    Pierce-Bancroft, A.F.2    Prasad, B.M.3
  • 48
    • 0033358548 scopus 로고    scopus 로고
    • Use of unlinked genetic markers to detect population stratification in association studies
    • Pritchard, J.K. & Rosenberg, N.A. (1999) Use of unlinked genetic markers to detect population stratification in association studies. Am J Hum Genet 65, 220-228.
    • (1999) Am J Hum Genet , vol.65 , pp. 220-228
    • Pritchard, J.K.1    Rosenberg, N.A.2
  • 49
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard, J.K., Stephens, M. & Donnelly, P. (2000) Inference of population structure using multilocus genotype data. Genetics 155, 945-959.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 55
    • 34547513326 scopus 로고    scopus 로고
    • A role for BDNF in cocaine reward and relapse
    • Schoenbaum, G., Stalnaker, T.A. & Shaham, Y. (2007) A role for BDNF in cocaine reward and relapse. Nat Neurosci 10, 935-936.
    • (2007) Nat Neurosci , vol.10 , pp. 935-936
    • Schoenbaum, G.1    Stalnaker, T.A.2    Shaham, Y.3
  • 56
    • 0027257999 scopus 로고
    • Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys
    • Spealman, R.D. (1993) Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology (Berl) 112, 93-99.
    • (1993) Psychopharmacology (Berl) , vol.112 , pp. 93-99
    • Spealman, R.D.1
  • 57
    • 0036020892 scopus 로고    scopus 로고
    • A direct approach to false discovery Rates
    • Storey, J. (2002) A direct approach to false discovery Rates. J R Stat Soc Ser B 64, 479-498.
    • (2002) J R Stat Soc Ser B , vol.64 , pp. 479-498
    • Storey, J.1
  • 58
    • 43449123329 scopus 로고    scopus 로고
    • Neuroplasticity in the mesolimbic dopamine system and cocaine addiction
    • Thomas, M.J., Kalivas, P.W. & Shaham, Y. (2008) Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol 154, 327-342.
    • (2008) Br J Pharmacol , vol.154 , pp. 327-342
    • Thomas, M.J.1    Kalivas, P.W.2    Shaham, Y.3
  • 59
    • 0035209299 scopus 로고    scopus 로고
    • Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms
    • Uhl, G.R., Liu, Q.R., Walther, D., Hess, J. & Naiman, D. (2001) Polysubstance abuse-vulnerability genes: genome scans for association, using 1, 004 subjects and 1, 494 single-nucleotide polymorphisms. Am J Hum Genet 69, 1290-1300.
    • (2001) Am J Hum Genet , vol.69 , pp. 1290-1300
    • Uhl, G.R.1    Liu, Q.R.2    Walther, D.3    Hess, J.4    Naiman, D.5
  • 60
    • 54949105395 scopus 로고    scopus 로고
    • Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects
    • Uhl, G.R., Drgon, T., Johnson, C., Li, C.Y., Contoreggi, C., Hess, J., Naiman, D. & Liu, Q.R. (2008) Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects. Ann N Y Acad Sci 1141, 318-381.
    • (2008) Ann N Y Acad Sci , vol.1141 , pp. 318-381
    • Uhl, G.R.1    Drgon, T.2    Johnson, C.3    Li, C.Y.4    Contoreggi, C.5    Hess, J.6    Naiman, D.7    Liu, Q.R.8
  • 62
    • 0036199639 scopus 로고    scopus 로고
    • From first drug use to drug dependence; developmental periods of risk for dependence upon marijuana, cocaine, and alcohol
    • Wagner, F.A. & Anthony, J.C. (2002) From first drug use to drug dependence; developmental periods of risk for dependence upon marijuana, cocaine, and alcohol. Neuropsychopharmacology 26, 479-488.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 479-488
    • Wagner, F.A.1    Anthony, J.C.2


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