Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins

Archives of General Psychiatry

Volumn 57, Issue 3, 2000, Pages 261-269

  Kendler, Kenneth S ^a,b   Karkowski, Laura M ^a,b   Neale, Michael C ^a,b   Prescott, Carol A ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS; CENTRAL STIMULANT AGENT; COCAINE; OPIATE; PSYCHEDELIC AGENT; SEDATIVE AGENT;

ADULT; ARTICLE; DRUG ABUSE; DRUG ABUSE PATTERN; FAMILY LIFE; GENETIC VARIABILITY; HERITABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POPULATION RISK; PREVALENCE; RELIABILITY; TWIN ZYGOSITY; UNITED STATES;

EID: 0034012531     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.57.3.261     Document Type: Article

References (46)

1. Croughan JL. The contributions of family studies to understanding drug abuse. In: Robins LN, ed. Studying Drug Abuse. New Brunswick, NJ: Rutgers University Press; 1985:240-264.
2. Mirin SM, Weiss RD, Sollogub A, Michael J. Psychopathology in families of drug abusers. In: Mirin SM, ed. Substance Abuse and Psychopathology. Washington, DC: American Psychiatric Association Press; 1984:79-106.
3. Rounsaville BJ, Kosten TR, Weissman MM, Prusoff R, Pauls D, Anton SF, Merikangas K. Psychiatric disorders in relatives of probands with opiate addiction. Arch Gen Psychiatry. 1991;48:33-42.
4. Dinwiddie SH, Reich T. Genetic and family studies in psychiatric illness and alcohol and drug dependence. J Addict Dis. 1993;12:17-27.
5. Merikangas K, Stolar M, Stevens DE, Goulet J, Preisig MA, Fenton B, Zhang H, O'Malley SS, Rounsaville BJ. Familial transmission of substance use disorders. Arch Gen Psychiatry. 1998;55:973-979.
6. Bierut LJ, Dinwiddie SH, Begleiter H, Crowe RR, Hesselbrock V, Nurnberger JI Jr, Porjesz B, Schuckit MA, Reich T. Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. Arch Gen Psychiatry. 1998;55: 982-988.
7. Grove WM, Eckerl ED, Heston L. Bouchard TJ Jr, Segal N, Lykken DT. Heritability of substance abuse and antisocial behavior: a study of monozygote twins reared apart. Biol Psychiatry. 1990;27:1293-1304.
8. Tsuang MT, Lyons MJ, Eisen SA, Goldberg J, True W, Meyer JM, Eaves LJ. Genetic influences on abuse of illicit drugs: a study of 3,297 twin pairs. Am J Med Genet. 1996;67:473-477.
9. van den Bree MB, Johnson EO, Neale MC, Pickens RW. Genetic and environmental influences on drug use and abuse/dependence in male and female twins. Drug Alcohol Depend. 1998;52:231-241.
10. Tsuang MT, Lyons MJ, Meyer JM, Doyle T, Eisen SA, Goldberg J, TrueW, Lin N, Toomey R, Eaves L. Co-occurence of abuse of different drugs in men: the rate of drug-specific and shared vulnerabilities. Arch Gen Psychiatry. 1998;55:967-972.
11. Cadoret RJ, Troughton E, O'Gorman TW, Heywood E. An adoption study of genetic and environmental factors in drug abuse. Arch Gen Psychiatry. 1986;43: 1131-1136.
12. Cadoret RJ, Yates WR, Troughton E, Woodworth G, Stewart MA. Adoption study demonstrating two genetic pathways to drug abuse. Arch Gen Psychiatry. 1995; 52:42-52.
13. Cadoret RJ, Yates WR, Troughton E, Woodworth G, Stewart MA. An adoption study of drug abuse/dependency in females. Compr Psychiatry. 1996;37:88-94.
14. Kendler KS, Prescott CA. Cannabis use, abuse and dependence in a population-based sample of female twins. Am J Psychiatry. 1998;155:1016-1022.
15. Kendler KS, Prescott CA. Cocaine use, abuse and dependence in a population-based sample of female twins. Br J Psychiatry. 1998;173:345-350.
16. Kendler KS, Karkowski LM, Prescott CA. Hallucinogen, opiate, sedative and stimulant use and abuse in a population-based sample of female twins. Acta Psychiatr Scand. 1999;99:368-376.
17. SAS Institute. SAS/STAT User's Guide, Version 6, Fourth Edition. Vols 1 and 2. Cary, NC: SAS Institute Inc; 1990.
18. Spitzer RL, Williams JB, Gibbon J. Structured Clinical Interview for DSM-III-R-Patient Version. New York: New York State Psychiatric Institute; 1987.
19. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994.
20. Falconer DS. The inheritance of liability to certain diseases, estimated from the incidence among relatives. Ann Hum Genet. 1965;29:51-76.
21. Loehlin JC, Nichols RC. Heredity, Environment and Personality: A Study of 850 Sets of Twins. Austin: University of Texas Press; 1976.
22. Neale MC. Statistical Modelling With Mx. Richmond: Dept of Psychiatry, Medical College of Virginia, Virginia Commonwealth University; 1991.
23. Akaike H. Factor analysis and AIC. Psychometrika. 1987;52:317-332.
24. Feild HS, Armenakis AA. On use of multiple tests of significance in psychological research. Psychol Rep. 1974;35:427-431.
25. SAMHSA: National Household Survey on Drug Abuse Main Findings 1996. Rockville, Md: National Clearinghouse for Alcohol and Drug Information; 1998.
26. Kendler KS, Martin NG, Heath AC, Eaves LJ. Self-report psychiatric symptoms in twins and their nontwin relatives: are twins different? Am J Med Genet. 1995; 60:588-591.
27. Rutter M, Redshaw J. Annotation: growing up as a twin: twin-singleton differences in psychological development. J Child Psychol Psychiatry. 1991;32:885-395.
28. Kendler KS, Pedersen NL, Farahmand BY, Persson PG. The treated incidence of psychotic and affective illness in twins compared to population expectation: a study in the Swedish Twin and Psychiatric Registries. Psychol Med. 1996;26: 1135-1144.
29. Maes HH, Woodard CE, Murrelle L, Meyer JM, Silberg JL, Hewitt JK, Rutter M, Simonoff E, Pickles A, Carbonneau R, Neale MC, Eaves LJ. Tobacco, alcohol and drug use in eight-to-sixteen-year-old twins: the Virginia Twin Study of Adolescent Behavioral Development. J Stud Alcohol. 1999;60:293-305.
30. Allgulander C. Psychoactive drug use in a general population sample, Sweden: correlates with perceived health, psychiatric diagnoses, and mortality in an automated record-linkage study. Am J Public Health. 1989;79:1006-1010.
31. Kessler RC, Little RJ, Groves RM. Advances in strategies for minimizing and adjusting for survey nonresponse. Epidemiol Rev. 1995;17:192-204.
32. Kendler KS, Holm NV. Differential enrollment in twin registries: its effect on prevalence and concordance rates and estimates of genetic parameters. Acts Genet Med Gemellol (Roma). 1985;34:125-140.
33. Neale MC, Eaves LJ. Estimating and controlling for the effects of volunteer bias with pairs of relatives. Behav Genet. 1993;23:271-277.
34. Little RJ, Rubin DB. Statistical Analysis With Missing Data. New York, NY: John Wiley & Sons; 1987.
35. Kendler KS. Twin studies of psychiatric illness: current status and future directions. Arch Gen Psychiatry. 1993;50:905-915.
36. Hawkins JD, Catalano RF, Miller JY. Risk and protective factors for alcohol and other drug problems in adolescence and early adulthood: implications for substance abuse prevention. Psychol Bull. 1992;112:64-105.
37. Webster RA, Hunter M, Keats JA. Peer and parental influences on adolescents' substance use: a path analysis. Int J Addict. 1994;29:647-657.
38. Hettema JM, Neale MC, Kendler KS. Physical similarity and the equalenvironment assumption in twin studies of psychiatric disorders. Behav Genet. 1995;25:327-335.
39. Gynther LM, Carey G, Gottesman II, Vogler GP. A twin study of non-alcohol substance abuse. Psychiatry Res. 1995;56:213-220.
40. Jang KL, Livesley WJ, Vernon PA. Alcohol and drug problems: a multivariate behavioural genetic analysis of co-morbidity. Addiction. 1995;90:1213-1221.
41. Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ. A population-based twin study of major depression in women: the impact of varying definitions of illness. Arch Gen Psychiatry. 1992;49:257-266.
42. Kendler KS, Prescott CA. A population-based twin study of lifetime major depression in men and women. Arch Gen Psychiatry. 1999;56:39-44.
43. Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ. Panic disorder in women: a population-based twin study. Psychol Med. 1993;23:397-406.
44. Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ. The genetic epidemiology of phobias in women: the interrelationship of agoraphobia, social phobia, situational phobia, and simple phobia. Arch Gen Psychiatry. 1992;49:273-281.
45. Kendler KS, Neale MC, Sullivan PF, Corey LA, Gardner CO, Prescott CA. A population-based twin study in women of smoking initiation and nicotine dependence. Psychol Med. 1999; 29:299-308.
46. Straub RE, Sullivan PF, Ma Y, Myakishev MV, Harris-Kerr C, Wormley B, Kadambi B, Sadek H, Silverman MA, Webb BT, Neale MC, Bulik CM, Joyce PR, Kendler KS. Susceptibility genes for nicotine dependence: a genome scan and follow-up in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. Mol Psychiatry. 1999;4:129-144.