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Volumn 85, Issue 4, 2013, Pages 466-477

P2Y purinergic receptors: New targets for analgesic and antimigraine drugs

Author keywords

Algogens; Microglia; Migraine; Nucleotides; P2 receptors; Satellite glial cells

Indexed keywords

2 METHYLTHIOADENOSINE DIPHOSPHATE; 2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; 4 (2 IODO 6 METHYLAMINO 9H PURIN 9 YL) 2 PHOSPHONOOXYBICYCLO[3.1.0]HEXANE 1 METHANOL; ANALGESIC AGENT; ANTIMIGRAINE AGENT; AR C126313; CANGRELOR; CLOPIDOGREL; FERULIC ACID; MRS 2211; MRS 2395; MRS 2578; NF 340; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEOTIDE; PSB 0739; PSB 716; PUERARIN; PURINERGIC P2X RECEPTOR; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X3 RECEPTOR ANTAGONIST; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y RECEPTOR ANTAGONIST; SUMATRIPTAN; TETRAMETHYLPYRAZINE; TICAGRELOR; UNCLASSIFIED DRUG;

EID: 84872686735     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.10.027     Document Type: Note
Times cited : (56)

References (91)
  • 3
    • 84857045446 scopus 로고    scopus 로고
    • Purinergic signaling: Its unpopular beginning, its acceptance and its exciting future
    • G. Burnstock Purinergic signaling: its unpopular beginning, its acceptance and its exciting future Bioessays 34 2012 218 225
    • (2012) Bioessays , vol.34 , pp. 218-225
    • Burnstock, G.1
  • 4
    • 0015393308 scopus 로고
    • Purinergic nerves
    • G. Burnstock Purinergic nerves Pharmacol Rev 24 1972 509 581
    • (1972) Pharmacol Rev , vol.24 , pp. 509-581
    • Burnstock, G.1
  • 5
    • 33745738972 scopus 로고    scopus 로고
    • Purinergic signalling in neuron-glia interactions
    • R.D. Fields, and G. Burnstock Purinergic signalling in neuron-glia interactions Nat Rev Neurosci 7 2006 423 436
    • (2006) Nat Rev Neurosci , vol.7 , pp. 423-436
    • Fields, R.D.1    Burnstock, G.2
  • 6
    • 34547886861 scopus 로고    scopus 로고
    • The role of nucleotides in the neuron-glia communication responsible for the brain functions
    • K. Inoue, S. Koizumi, and M. Tsuda The role of nucleotides in the neuron-glia communication responsible for the brain functions J Neurochem 102 2007 1447 1458
    • (2007) J Neurochem , vol.102 , pp. 1447-1458
    • Inoue, K.1    Koizumi, S.2    Tsuda, M.3
  • 7
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • R.A. North Molecular physiology of P2X receptors Physiol Rev 82 2002 1013 1067
    • (2002) Physiol Rev , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 8
    • 0009464078 scopus 로고
    • Substances producing pain and itch
    • Edward Arnold Publisher London
    • C.A. Keele, and D. Armstrong Substances producing pain and itch Physiol Soc Monograph vol. 12 1964 Edward Arnold Publisher London p. 260-261
    • (1964) Physiol Soc Monograph , vol.12 , pp. 260-261
    • Keele, C.A.1    Armstrong, D.2
  • 9
    • 0014025239 scopus 로고
    • Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5′-triphosphate
    • H.O.J. Collier, G.W.L. James, and C. Schneider Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5′- triphosphate Nature 212 1966 411 412
    • (1966) Nature , vol.212 , pp. 411-412
    • Collier, H.O.J.1    James, G.W.L.2    Schneider, C.3
  • 10
    • 0019522124 scopus 로고
    • Pathophysiology of migraine: A new hypothesis
    • G. Burnstock Pathophysiology of migraine: a new hypothesis Lancet 1 1981 1397 1399
    • (1981) Lancet , vol.1 , pp. 1397-1399
    • Burnstock, G.1
  • 11
    • 0005342416 scopus 로고
    • Is ATP a central synaptic mediator for certain primary afferent fibres from mammalian skin?
    • R.E.W. Fyffe, and E.R. Perl Is ATP a central synaptic mediator for certain primary afferent fibres from mammalian skin? Proc Natl Acad Sci USA 81 1984 6890 6893
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6890-6893
    • Fyffe, R.E.W.1    Perl, E.R.2
  • 13
    • 33745158781 scopus 로고    scopus 로고
    • Purinergic P2 receptors as targets for novel analgesics
    • G. Burnstock Purinergic P2 receptors as targets for novel analgesics Pharmacol Ther 110 2006 433 454
    • (2006) Pharmacol Ther , vol.110 , pp. 433-454
    • Burnstock, G.1
  • 14
    • 84857237607 scopus 로고    scopus 로고
    • Targeting the visceral purinergic system for pain control
    • G. Burnstock Targeting the visceral purinergic system for pain control Curr Opin Pharmacol 12 2011 1 7
    • (2011) Curr Opin Pharmacol , vol.12 , pp. 1-7
    • Burnstock, G.1
  • 15
    • 33745623434 scopus 로고    scopus 로고
    • Delayed upregulation of ATP P2X3 receptors of trigeminal sensory neurons by calcitonin gene-related peptide
    • E. Fabbretti, M. D'Arco, A. Fabbro, M. Simonetti, A. Nistri, and R. Giniatullin Delayed upregulation of ATP P2X3 receptors of trigeminal sensory neurons by calcitonin gene-related peptide J Neurosci 26 2006 6163 6171
    • (2006) J Neurosci , vol.26 , pp. 6163-6171
    • Fabbretti, E.1    D'Arco, M.2    Fabbro, A.3    Simonetti, M.4    Nistri, A.5    Giniatullin, R.6
  • 16
    • 34547678377 scopus 로고    scopus 로고
    • Neutralization of nerve growth factor induces plasticity of ATP-sensitive P2X3 receptors of nociceptive trigeminal ganglion neurons
    • M. D'Arco, R. Giniatullin, M. Simonetti, A. Fabbro, A. Nair, and A. Nistri Neutralization of nerve growth factor induces plasticity of ATP-sensitive P2X3 receptors of nociceptive trigeminal ganglion neurons J Neurosci 27 2007 8190 8201
    • (2007) J Neurosci , vol.27 , pp. 8190-8201
    • D'Arco, M.1    Giniatullin, R.2    Simonetti, M.3    Fabbro, A.4    Nair, A.5    Nistri, A.6
  • 17
    • 50349094014 scopus 로고    scopus 로고
    • Molecular mechanisms of sensitization of pain-transducing P2X3 receptors by the migraine mediators CGRP and NGF
    • R. Giniatullin, A. Nistri, and E. Fabbretti Molecular mechanisms of sensitization of pain-transducing P2X3 receptors by the migraine mediators CGRP and NGF Mol Neurobiol 37 2008 83 90
    • (2008) Mol Neurobiol , vol.37 , pp. 83-90
    • Giniatullin, R.1    Nistri, A.2    Fabbretti, E.3
  • 18
    • 49649113201 scopus 로고    scopus 로고
    • Mechanisms mediating the enhanced gene transcription of P2X3 receptor by calcitonin gene-related peptide in trigeminal sensory neurons
    • M. Simonetti, R. Giniatullin, and E. Fabbretti Mechanisms mediating the enhanced gene transcription of P2X3 receptor by calcitonin gene-related peptide in trigeminal sensory neurons J Biol Chem 27 2008 18743 18752
    • (2008) J Biol Chem , vol.27 , pp. 18743-18752
    • Simonetti, M.1    Giniatullin, R.2    Fabbretti, E.3
  • 19
    • 20444453576 scopus 로고    scopus 로고
    • Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats
    • M. Shinoda, N. Ozaki, H. Asai, K. Nagamine, and Y. Sugiura Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats Pain 116 2005 42 51
    • (2005) Pain , vol.116 , pp. 42-51
    • Shinoda, M.1    Ozaki, N.2    Asai, H.3    Nagamine, K.4    Sugiura, Y.5
  • 20
    • 25644443793 scopus 로고    scopus 로고
    • Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation
    • R. Ambalavanar, M. Moritani, and D. Dessem Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation Pain 117 2005 280 291
    • (2005) Pain , vol.117 , pp. 280-291
    • Ambalavanar, R.1    Moritani, M.2    Dessem, D.3
  • 21
    • 80053173506 scopus 로고    scopus 로고
    • Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model
    • A. Gnanasekaran, M. Sundukova, A.M.J.M. van den Maagdenberg, E. Fabbretti, and A. Nistri Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model Mol Pain 7 2011 77
    • (2011) Mol Pain , vol.7 , pp. 77
    • Gnanasekaran, A.1    Sundukova, M.2    Van Den Maagdenberg, A.M.J.M.3    Fabbretti, E.4    Nistri, A.5
  • 23
    • 84864055317 scopus 로고    scopus 로고
    • Migraine: A disorder of brain excitatory-inhibitory balance?
    • D. Vecchia, and D. Pietrobon Migraine: a disorder of brain excitatory-inhibitory balance? Trends Neurosci 35 2012 507 520
    • (2012) Trends Neurosci , vol.35 , pp. 507-520
    • Vecchia, D.1    Pietrobon, D.2
  • 26
    • 84859267068 scopus 로고    scopus 로고
    • The inhibitory action of the antimigraine nonsteroidal anti-inflammatory drug naproxen on P2X3 receptor-mediated responses in rat trigeminal neurons
    • T. Hautaniemi, N. Petrenko, A. Skorinkin, and R. Giniatullin The inhibitory action of the antimigraine nonsteroidal anti-inflammatory drug naproxen on P2X3 receptor-mediated responses in rat trigeminal neurons Neuroscience 209 2012 32 38
    • (2012) Neuroscience , vol.209 , pp. 32-38
    • Hautaniemi, T.1    Petrenko, N.2    Skorinkin, A.3    Giniatullin, R.4
  • 27
    • 77958112584 scopus 로고    scopus 로고
    • P2X receptors and modulation of pain transmission: Focus on effects of drugs and compounds used in traditional Chinese medicine
    • S. Liang, C. Xu, G. Li, and Y. Gao P2X receptors and modulation of pain transmission: focus on effects of drugs and compounds used in traditional Chinese medicine Neurochem Int 57 2010 705 712
    • (2010) Neurochem Int , vol.57 , pp. 705-712
    • Liang, S.1    Xu, C.2    Li, G.3    Gao, Y.4
  • 28
    • 84856298187 scopus 로고    scopus 로고
    • In pursuit of P2X3 antagonists: Novel therapeutics for chronic pain and afferent sensitization
    • A.P. Ford In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization Purinergic Signal 8 Suppl. 1 2012 S3 S26
    • (2012) Purinergic Signal , vol.8 , Issue.SUPPL. 1
    • Ford, A.P.1
  • 30
    • 0346846752 scopus 로고    scopus 로고
    • 4 receptors in dorsal root, nodose and trigeminal ganglia of the rat
    • 4 receptors in dorsal root, nodose and trigeminal ganglia of the rat Histochem Cell Biol 120 2003 415 426
    • (2003) Histochem Cell Biol , vol.120 , pp. 415-426
    • Ruan, H.Z.1    Burnstock, G.2
  • 31
    • 33747189475 scopus 로고    scopus 로고
    • Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord
    • K. Kobayashi, T. Fukuoka, H. Yamanaka, Y. Dai, K. Obata, and A. Tokunaga Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord J Comp Neurol 498 2006 443 454
    • (2006) J Comp Neurol , vol.498 , pp. 443-454
    • Kobayashi, K.1    Fukuoka, T.2    Yamanaka, H.3    Dai, Y.4    Obata, K.5    Tokunaga, A.6
  • 32
    • 77950838144 scopus 로고    scopus 로고
    • Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior
    • S.A. Malin, and D.C. Molliver Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior Mol Pain 6 2010 21
    • (2010) Mol Pain , vol.6 , pp. 21
    • Malin, S.A.1    Molliver, D.C.2
  • 33
    • 0038573980 scopus 로고    scopus 로고
    • Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity
    • T. Moriyama, T. Iida, K. Kobayashi, T. Higashi, T. Fukuoka, and H. Tsumura Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity J Neurosci 23 2003 6058 6062
    • (2003) J Neurosci , vol.23 , pp. 6058-6062
    • Moriyama, T.1    Iida, T.2    Kobayashi, K.3    Higashi, T.4    Fukuoka, T.5    Tsumura, H.6
  • 34
    • 34248576759 scopus 로고    scopus 로고
    • Physiology and pathophysiology of purinergic neurotransmission
    • G. Burnstock Physiology and pathophysiology of purinergic neurotransmission Physiol Rev 87 2007 659 797
    • (2007) Physiol Rev , vol.87 , pp. 659-797
    • Burnstock, G.1
  • 35
    • 20444406095 scopus 로고    scopus 로고
    • P2Y receptors and pain transmission
    • Z. Gerevich, and P. Illes P2Y receptors and pain transmission Purinergic Signal 1 2004 3 10
    • (2004) Purinergic Signal , vol.1 , pp. 3-10
    • Gerevich, Z.1    Illes, P.2
  • 36
    • 70349931496 scopus 로고    scopus 로고
    • Purines and sensory nerves
    • G. Burnstock Purines and sensory nerves Handb Exp Pharmacol 194 2009 333 392
    • (2009) Handb Exp Pharmacol , vol.194 , pp. 333-392
    • Burnstock, G.1
  • 37
    • 42649085439 scopus 로고    scopus 로고
    • Purinoceptor-mediated calcium signaling in primary neuron-glia trigeminal cultures
    • S. Ceruti, M. Fumagalli, G. Villa, C. Verderio, and M.P. Abbracchio Purinoceptor-mediated calcium signaling in primary neuron-glia trigeminal cultures Cell Calcium 43 2008 576 590
    • (2008) Cell Calcium , vol.43 , pp. 576-590
    • Ceruti, S.1    Fumagalli, M.2    Villa, G.3    Verderio, C.4    Abbracchio, M.P.5
  • 38
    • 0742322860 scopus 로고    scopus 로고
    • Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia
    • Z. Gerevich, S.J. Borvendeg, W. Schroder, H. Franke, K. Wirkner, and W. Norenberg Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia J Neurosci 24 2004 797 807
    • (2004) J Neurosci , vol.24 , pp. 797-807
    • Gerevich, Z.1    Borvendeg, S.J.2    Schroder, W.3    Franke, H.4    Wirkner, K.5    Norenberg, W.6
  • 39
    • 26444575422 scopus 로고    scopus 로고
    • 1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons
    • 1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons Eur J Pharmacol 521 2005 34 38
    • (2005) Eur J Pharmacol , vol.521 , pp. 34-38
    • Gerevich, Z.1    Muller, C.2    Illes, P.3
  • 40
    • 0035810934 scopus 로고    scopus 로고
    • Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia
    • M. Tominaga, M. Wada, and M. Masu Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia Proc Natl Acad Sci USA 98 2001 6951 6956
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6951-6956
    • Tominaga, M.1    Wada, M.2    Masu, M.3
  • 41
    • 0036835305 scopus 로고    scopus 로고
    • ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2
    • D.C. Molliver, S.P. Cook, J.A. Carlsten, D.E. Wright, and E.W. McCleskey ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2 Eur J Neurosci 16 2002 1850 1860
    • (2002) Eur J Neurosci , vol.16 , pp. 1850-1860
    • Molliver, D.C.1    Cook, S.P.2    Carlsten, J.A.3    Wright, D.E.4    McCleskey, E.W.5
  • 43
    • 0037052694 scopus 로고    scopus 로고
    • Increase in intracellular Ca(2+) and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons
    • M. Sanada, H. Yasuda, M. Omatsu-Kanbe, K. Sango, T. Isono, and H. Matsuura Increase in intracellular Ca(2+) and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons Neuroscience 111 2002 413 422
    • (2002) Neuroscience , vol.111 , pp. 413-422
    • Sanada, M.1    Yasuda, H.2    Omatsu-Kanbe, M.3    Sango, K.4    Isono, T.5    Matsuura, H.6
  • 44
    • 0036284227 scopus 로고    scopus 로고
    • ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater
    • K. Zimmermann, P.W. Reeh, and B. Averbeck ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater Pain 97 2002 259 265
    • (2002) Pain , vol.97 , pp. 259-265
    • Zimmermann, K.1    Reeh, P.W.2    Averbeck, B.3
  • 45
    • 0041932138 scopus 로고    scopus 로고
    • ATP augments peptide release from rat sensory neurons in culture through activation of P2Y receptors
    • H. Huang, X. Wu, G.D. Nicol, S. Meller, and M.R. Vasko ATP augments peptide release from rat sensory neurons in culture through activation of P2Y receptors J Pharmacol Exp Ther 306 2003 1137 1144
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 1137-1144
    • Huang, H.1    Wu, X.2    Nicol, G.D.3    Meller, S.4    Vasko, M.R.5
  • 46
    • 1842685379 scopus 로고    scopus 로고
    • The P2Y agonist UTP activates cutaneous afferent fibers
    • C.L. Stucky, K.A. Medler, and D.C. Molliver The P2Y agonist UTP activates cutaneous afferent fibers Pain 109 2004 36 44
    • (2004) Pain , vol.109 , pp. 36-44
    • Stucky, C.L.1    Medler, K.A.2    Molliver, D.C.3
  • 47
    • 1642314088 scopus 로고    scopus 로고
    • Modulation of sodium currents in rat sensory neurons by nucleotides
    • S.Y. Park, H.I. Kim, Y.K. Shin, C.S. Lee, M. Park, and J.H. Song Modulation of sodium currents in rat sensory neurons by nucleotides Brain Res 1006 2004 168 176
    • (2004) Brain Res , vol.1006 , pp. 168-176
    • Park, S.Y.1    Kim, H.I.2    Shin, Y.K.3    Lee, C.S.4    Park, M.5    Song, J.H.6
  • 48
    • 34547103866 scopus 로고    scopus 로고
    • 2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels
    • 2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels J Neurosci 27 2007 8914 8926
    • (2007) J Neurosci , vol.27 , pp. 8914-8926
    • Zaika, O.1    Tolstykh, G.P.2    Jaffe, D.B.3    Shapiro, M.S.4
  • 49
    • 4944229740 scopus 로고    scopus 로고
    • Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors
    • A.K. Filippov, J.M. Fernandez-Fernandez, S.J. Marsh, J. Simon, E.A. Barnard, and D.A. Brown Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors Mol Pharmacol 66 2004 468 477
    • (2004) Mol Pharmacol , vol.66 , pp. 468-477
    • Filippov, A.K.1    Fernandez-Fernandez, J.M.2    Marsh, S.J.3    Simon, J.4    Barnard, E.A.5    Brown, D.A.6
  • 51
    • 79960451796 scopus 로고    scopus 로고
    • Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade
    • A. Yousuf, F. Klinger, K. Schicker, and S. Boehm Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade Pain 152 2011 1899 1908
    • (2011) Pain , vol.152 , pp. 1899-1908
    • Yousuf, A.1    Klinger, F.2    Schicker, K.3    Boehm, S.4
  • 52
    • 0037062494 scopus 로고    scopus 로고
    • Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain
    • H.S. Xiao, Q.H. Huang, F.X. Zhang, L. Bao, Y.J. Lu, and C. Guo Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain Proc Natl Acad Sci USA 99 2002 8360 8365
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8360-8365
    • Xiao, H.S.1    Huang, Q.H.2    Zhang, F.X.3    Bao, L.4    Lu, Y.J.5    Guo, C.6
  • 53
    • 60849111097 scopus 로고    scopus 로고
    • Sensitization of cutaneous nociceptors after nerve transection and regeneration: Possible role of target-derived neurotrophic factor signaling
    • M.P. Jankowski, J.J. Lawson, S.L. McIlwrath, K.K. Rau, C.E. Anderson, and K.M. Albers Sensitization of cutaneous nociceptors after nerve transection and regeneration: possible role of target-derived neurotrophic factor signaling J Neurosci 29 2009 1636 1647
    • (2009) J Neurosci , vol.29 , pp. 1636-1647
    • Jankowski, M.P.1    Lawson, J.J.2    McIlwrath, S.L.3    Rau, K.K.4    Anderson, C.E.5    Albers, K.M.6
  • 56
    • 81955162999 scopus 로고    scopus 로고
    • Regional expression of P2Y(4) receptors in the rat central nervous system
    • X. Song, W. Guo, Q. Yu, X. Liu, Z. Xiang, and C. He Regional expression of P2Y(4) receptors in the rat central nervous system Purinergic Signal 7 2011 469 488
    • (2011) Purinergic Signal , vol.7 , pp. 469-488
    • Song, X.1    Guo, W.2    Yu, Q.3    Liu, X.4    Xiang, Z.5    He, C.6
  • 57
    • 0036784496 scopus 로고    scopus 로고
    • Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats
    • M. Okada, T. Nakagawa, M. Minami, and M. Satoh Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats J Pharmacol Exp Ther 303 2002 66 73
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 66-73
    • Okada, M.1    Nakagawa, T.2    Minami, M.3    Satoh, M.4
  • 58
    • 79951652761 scopus 로고    scopus 로고
    • Spinal astrocytes as therapeutic targets for pathological pain
    • T. Nakagawa, and S. Kaneko Spinal astrocytes as therapeutic targets for pathological pain J Pharmacol Sci 114 2010 347 353
    • (2010) J Pharmacol Sci , vol.114 , pp. 347-353
    • Nakagawa, T.1    Kaneko, S.2
  • 59
    • 77957331971 scopus 로고    scopus 로고
    • The structure of the perineuronal sheath of satellite glial cells (SGCs) in sensory ganglia
    • E. Pannese The structure of the perineuronal sheath of satellite glial cells (SGCs) in sensory ganglia Neuron Glia Biol 6 2010 3 10
    • (2010) Neuron Glia Biol , vol.6 , pp. 3-10
    • Pannese, E.1
  • 60
    • 77956338290 scopus 로고    scopus 로고
    • Bidirectional calcium signaling between satellite glial cells and neurons in cultured mouse trigeminal ganglia
    • S.O. Suadicani, P.S. Cherkas, J. Zuckerman, D.N. Smith, D.C. Spray, and M. Hanani Bidirectional calcium signaling between satellite glial cells and neurons in cultured mouse trigeminal ganglia Neuron Glia Biol 6 2010 43 51
    • (2010) Neuron Glia Biol , vol.6 , pp. 43-51
    • Suadicani, S.O.1    Cherkas, P.S.2    Zuckerman, J.3    Smith, D.N.4    Spray, D.C.5    Hanani, M.6
  • 61
    • 73449108381 scopus 로고    scopus 로고
    • The neural-glial purinergic receptor ensemble in chronic pain states
    • M.F. Jarvis The neural-glial purinergic receptor ensemble in chronic pain states Trends Neurosci 33 2010 48 57
    • (2010) Trends Neurosci , vol.33 , pp. 48-57
    • Jarvis, M.F.1
  • 62
    • 34547483582 scopus 로고    scopus 로고
    • Neuronal somatic ATP release triggers neuron-satellite glial cell communication in dorsal root ganglia
    • X. Zhang, Y. Chen, C. Wang, and L-Y.M. Huang Neuronal somatic ATP release triggers neuron-satellite glial cell communication in dorsal root ganglia Proc Natl Acad Sci USA 104 2007 9864 9869
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9864-9869
    • Zhang, X.1    Chen, Y.2    Wang, C.3    Huang, L.-Y.M.4
  • 63
    • 84864487226 scopus 로고    scopus 로고
    • P2X4R+ microglia drive neuropathic pain
    • S. Beggs, T. Trang, and M.W. Salter P2X4R+ microglia drive neuropathic pain Nat Neurosci 15 2012 1068 1073
    • (2012) Nat Neurosci , vol.15 , pp. 1068-1073
    • Beggs, S.1    Trang, T.2    Salter, M.W.3
  • 64
  • 65
    • 56149096976 scopus 로고    scopus 로고
    • Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain
    • L. Ulmann, J.P. Hatcher, J.P. Hughes, S. Chaumont, P.J. Green, and F. Conquet Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain J Neurosci 28 2008 11263 11268
    • (2008) J Neurosci , vol.28 , pp. 11263-11268
    • Ulmann, L.1    Hatcher, J.P.2    Hughes, J.P.3    Chaumont, S.4    Green, P.J.5    Conquet, F.6
  • 66
    • 63849192564 scopus 로고    scopus 로고
    • P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation
    • T. Trang, S. Beggs, X. Wan, and M.W. Salter P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation J Neurosci 29 2009 3518 3528
    • (2009) J Neurosci , vol.29 , pp. 3518-3528
    • Trang, T.1    Beggs, S.2    Wan, X.3    Salter, M.W.4
  • 67
    • 79955623602 scopus 로고    scopus 로고
    • Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development
    • K. Biber, M. Tsuda, H. Tozaki-Saitoh, K. Tsukamoto, E. Toyomitsu, and T. Masuda Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development EMBO J 30 2011 1864 1873
    • (2011) EMBO J , vol.30 , pp. 1864-1873
    • Biber, K.1    Tsuda, M.2    Tozaki-Saitoh, H.3    Tsukamoto, K.4    Toyomitsu, E.5    Masuda, T.6
  • 68
    • 67650222417 scopus 로고    scopus 로고
    • Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
    • M. Tsuda, K. Kuboyama, T. Inoue, K. Nagata, H. Tozaki-Saitoh, and K. Inoue Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays Mol Pain 5 2009 28
    • (2009) Mol Pain , vol.5 , pp. 28
    • Tsuda, M.1    Kuboyama, K.2    Inoue, T.3    Nagata, K.4    Tozaki-Saitoh, H.5    Inoue, K.6
  • 69
    • 84858070953 scopus 로고    scopus 로고
    • P2X4 receptor channels form large noncytolytic pores in resting and activated microglia
    • L.P. Bernier, A.R. Ase, E. Boué-Grabot, and P. Séguéla P2X4 receptor channels form large noncytolytic pores in resting and activated microglia Glia 60 2012 728 737
    • (2012) Glia , vol.60 , pp. 728-737
    • Bernier, L.P.1    Ase, A.R.2    Boué-Grabot, E.3    Séguéla, P.4
  • 74
    • 77952573195 scopus 로고    scopus 로고
    • 12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP
    • 12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP Glia 58 2010 790 801
    • (2010) Glia , vol.58 , pp. 790-801
    • Ohsawa, K.1    Irino, Y.2    Sanagi, T.3    Nakamura, Y.4    Suzuki, E.5    Inoue, K.6
  • 75
    • 84865315587 scopus 로고    scopus 로고
    • Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury
    • K. Kobayashi, H. Yamanaka, F. Yanamoto, M. Okubo, and K. Noguchi Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury Glia 60 2012 1529 1539
    • (2012) Glia , vol.60 , pp. 1529-1539
    • Kobayashi, K.1    Yamanaka, H.2    Yanamoto, F.3    Okubo, M.4    Noguchi, K.5
  • 76
    • 71749103005 scopus 로고    scopus 로고
    • Astrocytes in the damaged brain: Molecular and cellular insights into their reactive response and healing potential
    • A. Buffo, C. Rolando, and S. Ceruti Astrocytes in the damaged brain: molecular and cellular insights into their reactive response and healing potential Biochem Pharmacol 79 2010 77 89
    • (2010) Biochem Pharmacol , vol.79 , pp. 77-89
    • Buffo, A.1    Rolando, C.2    Ceruti, S.3
  • 77
    • 34047267326 scopus 로고    scopus 로고
    • Enhanced excitability of nociceptive trigeminal ganglion neurons by satellite glial cytokine following peripheral inflammation
    • M. Takeda, T. Tanimoto, J. Kadoi, M. Nasu, M. Takahashi, and J. Kitagawa Enhanced excitability of nociceptive trigeminal ganglion neurons by satellite glial cytokine following peripheral inflammation Pain 129 2007 155 166
    • (2007) Pain , vol.129 , pp. 155-166
    • Takeda, M.1    Tanimoto, T.2    Kadoi, J.3    Nasu, M.4    Takahashi, M.5    Kitagawa, J.6
  • 78
    • 77949653004 scopus 로고    scopus 로고
    • Differential expression of connexins in trigeminal ganglion neurons and satellite glial cells in response to chronic or acute joint inflammation
    • F.G. Garrett, and P.L. Durham Differential expression of connexins in trigeminal ganglion neurons and satellite glial cells in response to chronic or acute joint inflammation Neuron Glia Biol 4 2008 295 306
    • (2008) Neuron Glia Biol , vol.4 , pp. 295-306
    • Garrett, F.G.1    Durham, P.L.2
  • 79
    • 70449517367 scopus 로고    scopus 로고
    • Augmentation in gap junction-mediated cell coupling in dorsal root ganglia following sciatic nerve neuritis in the mouse
    • M. Ledda, E. Blum, S. De Palo, and M. Hanani Augmentation in gap junction-mediated cell coupling in dorsal root ganglia following sciatic nerve neuritis in the mouse Neuroscience 164 2009 1538 1545
    • (2009) Neuroscience , vol.164 , pp. 1538-1545
    • Ledda, M.1    Blum, E.2    De Palo, S.3    Hanani, M.4
  • 80
    • 78650865137 scopus 로고    scopus 로고
    • Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and the spinal trigeminal nucleus
    • G. Villa, S. Ceruti, M. Zanardelli, G. Magni, L. Jasmin, and P.T. Ohara Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and the spinal trigeminal nucleus Mol Pain 6 2010 89
    • (2010) Mol Pain , vol.6 , pp. 89
    • Villa, G.1    Ceruti, S.2    Zanardelli, M.3    Magni, G.4    Jasmin, L.5    Ohara, P.T.6
  • 81
    • 65049086944 scopus 로고    scopus 로고
    • Contribution of the activation of satellite glia in sensory ganglia to pathological pain
    • M. Takeda, M. Takahashi, and S. Matsumoto Contribution of the activation of satellite glia in sensory ganglia to pathological pain Neurosci Biobehav Rev 33 2009 784 792
    • (2009) Neurosci Biobehav Rev , vol.33 , pp. 784-792
    • Takeda, M.1    Takahashi, M.2    Matsumoto, S.3
  • 82
    • 34447519060 scopus 로고    scopus 로고
    • Satellite glial cells in the trigeminal ganglion as a determinant of orofacial neuropathic pain
    • J.P. Vit, L. Jasmin, A. Bhargava, and P.T. Ohara Satellite glial cells in the trigeminal ganglion as a determinant of orofacial neuropathic pain Neuron Glia Biol 2 2006 247 257
    • (2006) Neuron Glia Biol , vol.2 , pp. 247-257
    • Vit, J.P.1    Jasmin, L.2    Bhargava, A.3    Ohara, P.T.4
  • 83
    • 77957353403 scopus 로고    scopus 로고
    • Can satellite glial cells be therapeutic targets for pain control?
    • L. Jasmin, J.P. Vit, A. Bhargava, and P.T. Ohara Can satellite glial cells be therapeutic targets for pain control? Neuron Glia Biol 6 2010 63 71
    • (2010) Neuron Glia Biol , vol.6 , pp. 63-71
    • Jasmin, L.1    Vit, J.P.2    Bhargava, A.3    Ohara, P.T.4
  • 84
    • 77957373612 scopus 로고    scopus 로고
    • Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: An update
    • G. Villa, M. Fumagalli, C. Verderio, M.P. Abbracchio, and S. Ceruti Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update Neuron Glia Biol 6 2010 31 42
    • (2010) Neuron Glia Biol , vol.6 , pp. 31-42
    • Villa, G.1    Fumagalli, M.2    Verderio, C.3    Abbracchio, M.P.4    Ceruti, S.5
  • 85
    • 79960008253 scopus 로고    scopus 로고
    • Peripheral inflammation upregulates P2X receptor expression in satellite glial cells of mouse trigeminal ganglia: A calcium imaging study
    • R. Kushnir, P.S. Cherkas, and M. Hanani Peripheral inflammation upregulates P2X receptor expression in satellite glial cells of mouse trigeminal ganglia: a calcium imaging study Neuropharmacology 61 2011 739 746
    • (2011) Neuropharmacology , vol.61 , pp. 739-746
    • Kushnir, R.1    Cherkas, P.S.2    Hanani, M.3
  • 87
    • 55949099672 scopus 로고    scopus 로고
    • Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons
    • Y. Chen, X. Zhang, C. Wang, G. Li, Y. Gu, and L.Y. Huang Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons Proc Natl Acad Sci USA 105 2008 16773 16778
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16773-16778
    • Chen, Y.1    Zhang, X.2    Wang, C.3    Li, G.4    Gu, Y.5    Huang, L.Y.6
  • 88
    • 20144375454 scopus 로고    scopus 로고
    • Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
    • I.P. Chessell, J.P. Hatcher, C. Bountra, A.D. Michel, J.P. Hughes, and P. Green Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain Pain 114 2005 386 396
    • (2005) Pain , vol.114 , pp. 386-396
    • Chessell, I.P.1    Hatcher, J.P.2    Bountra, C.3    Michel, A.D.4    Hughes, J.P.5    Green, P.6
  • 89
    • 84862777282 scopus 로고    scopus 로고
    • Genetically determined P2X7 receptor pore formation regulated variability in chronic pain sensitivity
    • R.E. Sorge, T. Trang, R. Dorfman, S.B. Smith, S. Beggs, and J. Ritchie Genetically determined P2X7 receptor pore formation regulated variability in chronic pain sensitivity Nat Med 18 2012 595 599
    • (2012) Nat Med , vol.18 , pp. 595-599
    • Sorge, R.E.1    Trang, T.2    Dorfman, R.3    Smith, S.B.4    Beggs, S.5    Ritchie, J.6
  • 90
    • 84862784079 scopus 로고    scopus 로고
    • A series of case studies: Practical methodology for identifying antinociceptive multi-target drugs
    • M.H. Pang, Y. Kim, K.W. Jung, S. Cho, and D.H. Lee A series of case studies: practical methodology for identifying antinociceptive multi-target drugs Drug Discovery Today 17 2012 425 434
    • (2012) Drug Discovery Today , vol.17 , pp. 425-434
    • Pang, M.H.1    Kim, Y.2    Jung, K.W.3    Cho, S.4    Lee, D.H.5


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