CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 3, 2013, Pages

  Verhagen, Johan ^a   Genolet, Raphaël ^b   Britton, Graham J ^a   Stevenson, Brian J ^b,c   Sabatos Peyton, Catherine A ^a   Dyson, Julian ^d   Luescher, Immanuel F ^b   Wraith, David C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^d HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Costimulation; Experimental autoimmune encephalomyelitis; Immune regulation

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MYELIN BASIC PROTEIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CELL MATURATION; FEMALE; GENE DELETION; IMMUNOMODULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; THYMOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENIC VARIATION; CELL DIFFERENTIATION; COMPLEMENTARITY DETERMINING REGIONS; CTLA-4 ANTIGEN; CYTOKINES; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE REARRANGEMENT, T-LYMPHOCYTE; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SELF TOLERANCE; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

MUS MUSCULUS;

EID: 84872572798     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1208573110     Document Type: Article

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