Monoamine oxidase A and B inhibiting effect and molecular modeling of some synthesized coumarin derivatives

Neurochemistry International

Volumn 62, Issue 2, 2013, Pages 198-209

  Abdelhafez, Omaima M ^a   Amin, Kamelia M ^b   Ali, Hamed I ^c   Abdalla, Mohamed M ^d   Batran, Rasha Z ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c Helwan   (Egypt)

^d Mapco Pharmaceutical Industries Balteim   (Egypt)

Author keywords

7 Oxycoumarins; Acetohydrazides; Dioxopyrrolidines; MAO A and B; Molecular modeling

Indexed keywords

2 (3,4 DIMETHYL 2 OXO 2H CHROMEN 7 YLOXY) N (1,3 DIOXO ISOINDOLIN 2 YL)ACETAMIDE; 2 (3,4 DIMETHYL 2 OXO 2H CHROMEN 7 YLOXY) N (2,5 DIOXO 2H PYRROL 1(5H) YL)ACETAMIDE; 2 (3,4 DIMETHYL 2 OXO 2H CHROMEN 7 YLOXY) N' (2 OXOINDOLIN 3 YLIDENE) ACETOHYDRAZIDE; 2 (3,4 DIMETHYL 2 OXO 2H CHROMEN 7 YLOXY)N (2,5 DIOXO PYRROLIDIN 1 YL) ACETAMIDE; 2 (4 METHYL 2 OXO 2H CHROMEN 7 YLOXY) N (1,3 DIOXO ISOINDOLIN 2 YL) ACETAMIDE; 2 (4 METHYL 2 OXO 2H CHROMEN 7 YLOXY) N (2,5 DIOXO 2H PYRROL 1(5H) YL)ACETAMIDE; 2 (4 METHYL 2 OXO 2H CHROMEN 7 YLOXY) N (2,5 DIOXOPYRROLIDIN 1 YL) ACETAMIDE; 2 (4 METHYL 2 OXO 2H CHROMEN 7 YLOXY) N'(2 OXOINDOLIN 3 YLIDENE) ACETOHYDRAZIDE; 7 [2 (1,2 DIHYDRO 3 METHYL 5 OXO PYRAZOL 1 YL) 2 OXO ETHOXY] 4 METHYLCOUMARIN; 7 [2 (1,2 DIHYDRO 3 METHYL 5 OXO PYRAZOL 1 YL) 2 OXO ETHOXY] DIMETHYLCOUMARIN; 7 [2 (3,5 DIMETHYL 1H PYRAZOL 1 YL) 2 OXOETHOXY] 3,4 DIMETHYL COUMARIN; 7 [2 (3,5 DIMETHYL 1H PYRAZOL 1 YL) 2 OXOETHOXY] 4 METHYL COUMARIN; 7 [2 (3,5 DIOXO PYRAZOLIDIN 1 YL) 2 OXOETHOXY] 3,4 DIMETHYL COUMARIN; 7 [2 (3,5 DIOXO PYRAZOLIDIN 1 YL) 2 OXOETHOXY] 4 METHYL COUMARIN; ACETOHYDRAZIDE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; COUMARIN DERIVATIVE; DIOXOPYRROLIDINE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; DRUG INHIBITION; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RAT;

COUMARINS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS;

EID: 84872561091     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.11.005     Document Type: Article

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