Inhibition of monoamine oxidase by indole and benzofuran derivatives

European Journal of Medicinal Chemistry

Volumn 45, Issue 10, 2010, Pages 4458-4466

  Prins, Louis H A ^a   Petzer, Jacobus P ^a   Malan, Sarel F ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Benzofuran derivatives; Indole derivatives; LigandFit; Molecular docking; Monoamine oxidase (MAO); Parkinson's disease (PD)

Indexed keywords

1 METHYL N (2 METHYL 1H INDOL 5 YL) 1DELTA4 PYRIDINE 3 CARBOXAMIDE; 3 (3 CHLOROPHENYL) N (2 METHYL 1H INDOL 5 YL)PROP 2 ENAMIDE; 3 [(2 METHYL 1H INDOL 5 YL)CARBAMOYL]BENZENE 1 SULFONIC ACID; 3 CHLORO N (2 METHYL 1H INDOL 5 YL)BENZAMIDE; 3 CHLOROBENZOIC ACID 2 OXO 2,3 DIHYDRO BENZOFURAN 5 YL ESTER; 3 CHLOROCINNAMIC ACID 2 OXO 2,3 DIHYDRO BENZOFURAN 5 YL ESTER; 3,4 DICHLORO N (2 METHYL 1H INDOL 5 YL)BENZAMIDE; BENZOFURAN DERIVATIVE; BENZOIC ACID 2 OXO 2,3 DIHYDRO BENZOFURAN 5 YL ESTER; CINNAMIC ACID 2 OXO 2,3 DIHYDRO BENZOFURAN 5 YL ESTER; INDOLE DERIVATIVE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; N (2 METHYL 1H INDOL 5 YL) 3 PHENYLPROP 2 ENAMIDE; N (2 METHYL 1H INDOL 5 YL)BENZAMIDE; N (2 METHYL 1H INDOL 5 YL)CYCLOHEXANECARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); DEGENERATIVE DISEASE; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; MOLECULAR DOCKING; NONHUMAN; PARKINSON DISEASE;

BENZOFURANS; HUMANS; INDOLES; MODELS, MOLECULAR; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PARKINSON DISEASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77956189112     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.07.005     Document Type: Article

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