Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 24, 2002, Pages 3551-3555

  Carotti, Angelo ^a   Carrieri, Antonio ^a   Chimichi, Stefano ^b   Boccalini, Marco ^b   Cosimelli, Barbara ^c   Gnerre, Carmela ^d   Carotti, Andrea ^a   Carrupt, Pierre Alain ^d   Testa, Bernard ^d  

^a Dipartimento Farmaco Chimico   (Italy)

^b Dipartimento di Chimica Organica   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; GEIPARVARIN; MONOAMINE OXIDASE B INHIBITOR; AMINE OXIDASE (FLAVIN CONTAINING); COUMARIN DERIVATIVE; MONOAMINE OXIDASE INHIBITOR;

ARTICLE; DRUG EFFECT; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS;

COUMARINS; CRYSTALLOGRAPHY, X-RAY; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036889973     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00798-9     Document Type: Article

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