Inhibition of monoamine oxidase - A activity in rat brain by synthetic hydrazines: Structure-activity relationship (SAR)

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 20, Issue 3, 2005, Pages 269-274

  Dar, Ahsana ^a   Khan, Khalid M ^a   Ateeq, Humayun S ^a   Khan, Shagufta ^b   Rahat, Shagufta ^b   Perveen, Shahnaz ^c   Supuran, Claudiu T ^d  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b AGA KHAN UNIVERSITY   (Pakistan)

^c PCSIR LABORATORIES COMPLEX   (Pakistan)

^d UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Hydrazides; Inhibition; MAO A; Monoamine oxidase A; Rat brain; Structure activity

Indexed keywords

4 BENZYLOXYBENZOIC ACID CARBOHYDRAZIDE; 4 TOSYLBENZOIC ACID CARBOHYDRAZIDE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; ANTIDEPRESSANT AGENT; HYDRAZINE DERIVATIVE; MOCLOBEMIDE; MONOAMINE OXIDASE INHIBITOR; OXADIAZINE DERIVATIVE; OXIDIAZOLE DERIVATIVE; PHENELZINE; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FEMALE; FORCED SWIMMING TEST; IMMOBILIZATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TIME;

ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDRAZINES; MALE; MICE; MITOCHONDRIA; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; MOTOR ACTIVITY; PHENELZINE; RATS; RATS, WISTAR; SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 22544453906     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360400026212     Document Type: Article

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