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Volumn 4, Issue 11, 2012, Pages 803-822

Modeling of lamin A/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells

Author keywords

Dilated cardiomyopathy; Induced pluripotent stem cells; LMNA

Indexed keywords


EID: 84872506168     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100503     Document Type: Editorial
Times cited : (112)

References (54)
  • 1
    • 0027257461 scopus 로고
    • Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C
    • Lin F, Worman HJ. Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C. J Biol Chem. 1993;268:16321-16326.
    • (1993) J Biol Chem , vol.268 , pp. 16321-16326
    • Lin, F.1    Worman, H.J.2
  • 2
    • 33845286555 scopus 로고    scopus 로고
    • Human laminopathies: nuclei gone genetically awry
    • Capell BC, Collins FS. Human laminopathies: nuclei gone genetically awry. Nature reviews. 2006;7:940-952.
    • (2006) Nature reviews , vol.7 , pp. 940-952
    • Capell, B.C.1    Collins, F.S.2
  • 3
    • 33748296316 scopus 로고    scopus 로고
    • The laminopathies: a clinical review
    • Rankin J, Ellard S. The laminopathies: a clinical review. Clinical genetics. 2006;70:261-274.
    • (2006) Clinical genetics , vol.70 , pp. 261-274
    • Rankin, J.1    Ellard, S.2
  • 4
    • 68849119046 scopus 로고    scopus 로고
    • Laminopathies and the long strange trip from basic cell biology to therapy
    • Worman HJ, Fong LG, Muchir A, Young SG. Laminopathies and the long strange trip from basic cell biology to therapy. J Clin Invest. 2009;119:1825-1836.
    • (2009) J Clin Invest , vol.119 , pp. 1825-1836
    • Worman, H.J.1    Fong, L.G.2    Muchir, A.3    Young, S.G.4
  • 5
    • 33750379023 scopus 로고    scopus 로고
    • The laminopathies: the functional architecture of the nucleus and its contribution to disease
    • Burke B, Stewart CL. The laminopathies: the functional architecture of the nucleus and its contribution to disease. Annu Rev Genomics Hum Genet. 2006;7:369-405.
    • (2006) Annu Rev Genomics Hum Genet , vol.7 , pp. 369-405
    • Burke, B.1    Stewart, C.L.2
  • 6
    • 84856646656 scopus 로고    scopus 로고
    • Accelerated aging syndromes, are they relevant to normal human aging?
    • Dreesen O, Stewart CL. Accelerated aging syndromes, are they relevant to normal human aging? Aging (Albany NY). 2011;3:889-895.
    • (2011) Aging (Albany NY) , vol.3 , pp. 889-895
    • Dreesen, O.1    Stewart, C.L.2
  • 8
    • 64649105801 scopus 로고    scopus 로고
    • A novel mutation in LAMIN A/C is associated with isolated early-onset atrial fibrillation and progressive atrioventricular block followed by cardiomyopathy and sudden cardiac death
    • Pan H, Richards AA, Zhu X, Joglar JA, Yin HL, Garg V. A novel mutation in LAMIN A/C is associated with isolated early-onset atrial fibrillation and progressive atrioventricular block followed by cardiomyopathy and sudden cardiac death. Heart Rhythm. 2009;6:707-710.
    • (2009) Heart Rhythm , vol.6 , pp. 707-710
    • Pan, H.1    Richards, A.A.2    Zhu, X.3    Joglar, J.A.4    Yin, H.L.5    Garg, V.6
  • 10
    • 77952158022 scopus 로고    scopus 로고
    • The genetics of dilated cardiomyopathy
    • Dellefave L, McNally EM The genetics of dilated cardiomyopathy. Curr Opin Cardiol. 2010;25:198-204.
    • (2010) Curr Opin Cardiol , vol.25 , pp. 198-204
    • Dellefave, L.1    Mcnally E.M2
  • 17
    • 34248198298 scopus 로고    scopus 로고
    • Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy
    • Muchir A, Pavlidis P, Decostre V, Herron AJ, Arimura T, Bonne G, Worman HJ. Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy. J Clin Invest. 2007;117:1282-1293.
    • (2007) J Clin Invest , vol.117 , pp. 1282-1293
    • Muchir, A.1    Pavlidis, P.2    Decostre, V.3    Herron, A.J.4    Arimura, T.5    Bonne, G.6    Worman, H.J.7
  • 28
    • 0344629215 scopus 로고    scopus 로고
    • Loss of lamin A/C expression revealed by immuno-electron microscopy in dilated cardiomyopathy with atrioventricular block caused by LMNA gene defects
    • Verga L, Concardi M, Pilotto A, Bellini O, Pasotti M, Repetto A, Tavazzi L, Arbustini E. Loss of lamin A/C expression revealed by immuno-electron microscopy in dilated cardiomyopathy with atrioventricular block caused by LMNA gene defects. Virchows Arch. 2003;443:664-671.
    • (2003) Virchows Arch , vol.443 , pp. 664-671
    • Verga, L.1    Concardi, M.2    Pilotto, A.3    Bellini, O.4    Pasotti, M.5    Repetto, A.6    Tavazzi, L.7    Arbustini, E.8
  • 29
    • 0035153087 scopus 로고    scopus 로고
    • Lamins in disease: why do ubiquitously expressed nuclear envelope proteins give rise to tissue-specific disease phenotypes?
    • Hutchison CJ, Alvarez-Reyes M, Vaughan OA. Lamins in disease: why do ubiquitously expressed nuclear envelope proteins give rise to tissue-specific disease phenotypes? J Cell Sci. 2001;114:9-19.
    • (2001) J Cell Sci , vol.114 , pp. 9-19
    • Hutchison, C.J.1    Alvarez-Reyes, M.2    Vaughan, O.A.3
  • 31
    • 33745400562 scopus 로고    scopus 로고
    • Rapid electrical stimulation induces early activation of kinase signal transduction pathways and apoptosis in adult rat ventricular myocytes
    • Kuramochi Y, Guo X, Sawyer DB, Lim CC. Rapid electrical stimulation induces early activation of kinase signal transduction pathways and apoptosis in adult rat ventricular myocytes. Exp Physiol. 2006;91:773-780.
    • (2006) Exp Physiol , vol.91 , pp. 773-780
    • Kuramochi, Y.1    Guo, X.2    Sawyer, D.B.3    Lim, C.C.4
  • 32
    • 84862908072 scopus 로고    scopus 로고
    • Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene
    • Muchir A, Reilly SA, Wu W, Iwata S, Homma S, Bonne G, Worman HJ. Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene. Cardiovasc Res. 2012;93:311-319.
    • (2012) Cardiovasc Res , vol.93 , pp. 311-319
    • Muchir, A.1    Reilly, S.A.2    Wu, W.3    Iwata, S.4    Homma, S.5    Bonne, G.6    Worman, H.J.7
  • 36
    • 84864524683 scopus 로고    scopus 로고
    • Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation
    • Choi JC, Muchir A, Wu W, Iwata S, Homma S, Morrow JP, Worman HJ. Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation. Sci Transl Med. 2012;4:144ra102.
    • (2012) Sci Transl Med , vol.4
    • Choi, J.C.1    Muchir, A.2    Wu, W.3    Iwata, S.4    Homma, S.5    Morrow, J.P.6    Worman, H.J.7
  • 39
    • 80655140442 scopus 로고    scopus 로고
    • Progeria, rapamycin and normal aging: recent breakthrough
    • Blagosklonny MV. Progeria, rapamycin and normal aging: recent breakthrough. Aging (Albany NY). 2011;3:685-691
    • (2011) Aging (Albany NY) , vol.3 , pp. 685-691
    • Blagosklonny, M.V.1
  • 40
    • 79959776029 scopus 로고    scopus 로고
    • Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
    • Cao K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci Transl Med. 2011;3:89ra58.
    • (2011) Sci Transl Med , vol.3
    • Cao, K.1    Graziotto, J.J.2    Blair, C.D.3    Mazzulli, J.R.4    Erdos, M.R.5    Krainc, D.6    Collins, F.S.7
  • 42
    • 58049209788 scopus 로고    scopus 로고
    • Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins
    • Muchir A, Shan J, Bonne G, Lehnart SE, Worman HJ. Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins. Hum Mol Genet. 2009;18:241-247.
    • (2009) Hum Mol Genet , vol.18 , pp. 241-247
    • Muchir, A.1    Shan, J.2    Bonne, G.3    Lehnart, S.E.4    Worman, H.J.5
  • 47
    • 78649507841 scopus 로고    scopus 로고
    • ROCK inhibition facilitates the generation of humaninduced pluripotent stem cells in a defined, feeder-, and serumfree system
    • Lai WH, Ho JC, Lee YK, Ng KM, Au KW, Chan YC, Lau CP, Tse HF, Siu CW. ROCK inhibition facilitates the generation of humaninduced pluripotent stem cells in a defined, feeder-, and serumfree system. Cell Reprogram. 2010;12:641-653.
    • (2010) Cell Reprogram , vol.12 , pp. 641-653
    • Lai, W.H.1    Ho, J.C.2    Lee, Y.K.3    Ng, K.M.4    Au, K.W.5    Chan, Y.C.6    Lau, C.P.7    Tse, H.F.8    Siu, C.W.9
  • 48
    • 53449095205 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium
    • Chapter 1:Unit 1F 2
    • Mummery CL, Ward D, Passier R. Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium. Current protocols in stem cell biology 2007;Chapter 1:Unit 1F 2.
    • Current protocols in stem cell biology 2007
    • Mummery, C.L.1    Ward, D.2    Passier, R.3
  • 50
    • 82355168775 scopus 로고    scopus 로고
    • Siu SUPPLEMENTARY DATA CW. Calcium homeostasis in human induced pluripotent stem cell-derived cardiomyocytes
    • Lee YK, Ng KM, Lai WH, Chan YC, Lau YM, Lian Q, Tse HF, Siu SUPPLEMENTARY DATA CW. Calcium homeostasis in human induced pluripotent stem cell-derived cardiomyocytes. Stem Cell Rev. 2011;7:976-986.
    • (2011) Stem Cell Rev , vol.7 , pp. 976-986
    • Lee, Y.K.1    Ng, K.M.2    Lai, W.H.3    Chan, Y.C.4    Lau, Y.M.5    Lian, Q.6    Tse, H.F.7
  • 51
    • 79955884032 scopus 로고    scopus 로고
    • Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells
    • Ng KM, Lee YK, Lai WH, Chan YC, Fung ML, Tse HF, Siu CW. Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells. PLoS One. 2011;6:e19787.
    • (2011) PLoS One , vol.6
    • Ng, K.M.1    Lee, Y.K.2    Lai, W.H.3    Chan, Y.C.4    Fung, M.L.5    Tse, H.F.6    Siu, C.W.7
  • 52
    • 77956127107 scopus 로고    scopus 로고
    • Triiodothyronine promotes cardiac differentiation and maturation of embryonic stem cells via the classical genomic pathway
    • Lee YK, Ng KM, Chan YC, Lai WH, Au KW, Ho CY, Wong LY, Lau CP, Tse HF, Siu CW. Triiodothyronine promotes cardiac differentiation and maturation of embryonic stem cells via the classical genomic pathway. Mol Endocrinol. 2010;24:1728-1736.
    • (2010) Mol Endocrinol , vol.24 , pp. 1728-1736
    • Lee, Y.K.1    Ng, K.M.2    Chan, Y.C.3    Lai, W.H.4    Au, K.W.5    Ho, C.Y.6    Wong, L.Y.7    Lau, C.P.8    Tse, H.F.9    Siu, C.W.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.