Ouabain facilitates cardiac differentiation of mouse embryonic stem cells through ERK1/2 pathway

Acta Pharmacologica Sinica

Volumn 32, Issue 1, 2011, Pages 52-61

  Lee, Yee Ki ^a   Ng, Kwong Man ^a   Lai, Wing Hon ^a   Man, Cornelia ^c   Lieu, Deborah K ^b   Lau, Chu Pak ^a   Tse, Hung Fat ^a   Siu, Chung Wah ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

cardiac differentiation; embryonic stem cells; ouabain

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; OUABAIN; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TRANSCRIPTION FACTOR NKX2.5;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFECT; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CALCIUM; CARDIOTONIC AGENTS; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; GENE EXPRESSION; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; OUABAIN; SIGNAL TRANSDUCTION;

EID: 78651090015     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.188     Document Type: Article

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