Cardiomyocyte-specific overexpression of an active form of rac predisposes the heart to increased myocardial stunning and ischemia-reperfusion injury

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 2, 2013, Pages

  Hassan Talukder, M A ^a,b   Elnakish, Mohammad T ^a,b   Yang, Fuchun ^a,b   Nishijima, Yoshinori ^a,b   Alhaj, Mazin A ^a   Velayutham, Murugesan ^a,b   Hassanain, Hamdy H ^a,b   Zweier, Jay L ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Cardiac function; Infarction; Ischemia reperfusion; Zmracd expression

Indexed keywords

P21 ACTIVATED KINASE; RAC PROTEIN; RACD PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC PREDISPOSITION; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART RATE; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; STUNNED HEART MUSCLE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; GENOTYPE; HEART RATE; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIAL STUNNING; MYOCYTES, CARDIAC; NADPH OXIDASE; P21-ACTIVATED KINASES; PHENOTYPE; RAC GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SUPEROXIDES; TIME FACTORS; UP-REGULATION;

EID: 84872399731     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00367.2012     Document Type: Article

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