메뉴 건너뛰기




Volumn 7, Issue 8, 2012, Pages

Rac-induced left ventricular dilation in thyroxin-treated zmracd transgenic mice: Role of cardiomyocyte apoptosis and myocardial fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

CARVEDILOL; CASPASE 3; CASPASE 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PRAVASTATIN; RAC PROTEIN; SUPEROXIDE; THYROXINE;

EID: 84865287230     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042500     Document Type: Article
Times cited : (16)

References (61)
  • 1
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD, (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7: 589-600.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 2
    • 0037728841 scopus 로고    scopus 로고
    • Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations
    • Klein L, O'Connor CM, Gattis WA, Zampino M, de Luca L, et al. (2003) Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations. Am J Cardiol 91: 18F-40F.
    • (2003) Am J Cardiol , vol.91
    • Klein, L.1    O'Connor, C.M.2    Gattis, W.A.3    Zampino, M.4    de Luca, L.5
  • 3
    • 0037991449 scopus 로고    scopus 로고
    • Molecular determinants of myocardial hypertrophy and failure: alternative pathways for beneficial and maladaptive hypertrophy
    • Lips DJ, deWindt LJ, van Kraaij DJ, Doevendans PA, (2003) Molecular determinants of myocardial hypertrophy and failure: alternative pathways for beneficial and maladaptive hypertrophy. Eur Heart J 24: 883-896.
    • (2003) Eur Heart J , vol.24 , pp. 883-896
    • Lips, D.J.1    deWindt, L.J.2    van Kraaij, D.J.3    Doevendans, P.A.4
  • 5
    • 33847124544 scopus 로고    scopus 로고
    • Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets
    • Diwan A, Dorn GWII, (2007) Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets. Physiology 22: 56-64.
    • (2007) Physiology , vol.22 , pp. 56-64
    • Diwan, A.1    Dorn II, G.W.2
  • 6
    • 3242774502 scopus 로고    scopus 로고
    • Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence
    • Selvetella G, Hirsch E, Notte A, Tarone G, Lembo G, (2004) Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence. Cardiovasc Res 63: 373-380.
    • (2004) Cardiovasc Res , vol.63 , pp. 373-380
    • Selvetella, G.1    Hirsch, E.2    Notte, A.3    Tarone, G.4    Lembo, G.5
  • 7
    • 67649644872 scopus 로고    scopus 로고
    • Novel pharmacotherapies to abrogate postinfarction ventricular remodeling
    • Dorn GW, (2009) Novel pharmacotherapies to abrogate postinfarction ventricular remodeling. Nat Rev Cardiol 6: 283-291.
    • (2009) Nat Rev Cardiol , vol.6 , pp. 283-291
    • Dorn, G.W.1
  • 8
    • 78149478401 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale
    • Rose BA, Force T, Wang Y, (2010) Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 90: 1507-1546.
    • (2010) Physiol Rev , vol.90 , pp. 1507-1546
    • Rose, B.A.1    Force, T.2    Wang, Y.3
  • 10
    • 0034120364 scopus 로고    scopus 로고
    • Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1
    • Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, et al. (2000) Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. J Clin Invest 105: 875-886.
    • (2000) J Clin Invest , vol.105 , pp. 875-886
    • Sussman, M.A.1    Welch, S.2    Walker, A.3    Klevitsky, R.4    Hewett, T.E.5
  • 11
    • 0141841614 scopus 로고    scopus 로고
    • Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment
    • Maack C, Kartes T, Kilter H, Schäfers HJ, Nickenig G, et al. (2003) Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. Circulation 108: 1567-1574.
    • (2003) Circulation , vol.108 , pp. 1567-1574
    • Maack, C.1    Kartes, T.2    Kilter, H.3    Schäfers, H.J.4    Nickenig, G.5
  • 13
    • 0002537440 scopus 로고    scopus 로고
    • Cardiac hypertrophy: the good, the bad, and the ugly
    • Frey N, Olson EN, (2003) Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol 65: 45-79.
    • (2003) Annu Rev Physiol , vol.65 , pp. 45-79
    • Frey, N.1    Olson, E.N.2
  • 14
    • 84876678422 scopus 로고    scopus 로고
    • Concentrated Liquid Thyroid Hormone Composition
    • Pierres C, Gaugain-Hamidi A (2009) Concentrated Liquid Thyroid Hormone Composition. Patentdocs website. Available: http://www.faqs.org/patents/app/20090270507#ixzz1R067AyTq. Accessed: 2012 August 3.
    • (2009) Patentdocs website
    • Pierres, C.1    Gaugain-Hamidi, A.2
  • 15
    • 0025266820 scopus 로고
    • Ventricular remodeling after myocardial infarction
    • Pfeffer MA, Braunwald E, (1990) Ventricular remodeling after myocardial infarction. Circulation 81: 1161-1172.
    • (1990) Circulation , vol.81 , pp. 1161-1172
    • Pfeffer, M.A.1    Braunwald, E.2
  • 17
    • 0033862019 scopus 로고    scopus 로고
    • Low dose carvedilol inhibits progression of heart failure in rats with dilated cardiomyopathy
    • Watanabe K, Ohta Y, Nakazawa M, Higuchi H, Hasegawa G, et al. (2000) Low dose carvedilol inhibits progression of heart failure in rats with dilated cardiomyopathy. Br J Pharmacol 130: 1489-1495.
    • (2000) Br J Pharmacol , vol.130 , pp. 1489-1495
    • Watanabe, K.1    Ohta, Y.2    Nakazawa, M.3    Higuchi, H.4    Hasegawa, G.5
  • 18
    • 79951889870 scopus 로고    scopus 로고
    • K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity
    • Samuel MS, Lourenço FC, Olson MF, (2011) K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity. PLoS One 6: e17143.
    • (2011) PLoS One , vol.6
    • Samuel, M.S.1    Lourenço, F.C.2    Olson, M.F.3
  • 19
    • 79957716492 scopus 로고    scopus 로고
    • The Effect of Selective Antihypertensive Drugs on the Vascular Remodeling-associated Hypertension: Insights from a Profilin1 Transgenic Mouse Model
    • Hassona MD, Elnakish MT, Abouelnaga ZA, Alhaj M, Wani AA, et al. (2011) The Effect of Selective Antihypertensive Drugs on the Vascular Remodeling-associated Hypertension: Insights from a Profilin1 Transgenic Mouse Model. J Cardiovasc Pharmacol 57: 550-558.
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 550-558
    • Hassona, M.D.1    Elnakish, M.T.2    Abouelnaga, Z.A.3    Alhaj, M.4    Wani, A.A.5
  • 20
    • 0029873049 scopus 로고    scopus 로고
    • Carvedilol, a novel vasodilating beta-blocker with the potential for cardiovascular organ protection
    • Feuerstein GZ, Ruffolo RR Jr, (1996) Carvedilol, a novel vasodilating beta-blocker with the potential for cardiovascular organ protection. Eur Heart J 17: 24-29.
    • (1996) Eur Heart J , vol.17 , pp. 24-29
    • Feuerstein, G.Z.1    Ruffolo Jr., R.R.2
  • 21
    • 33751367853 scopus 로고    scopus 로고
    • The possible role of caspase-3 in pathological and physiological cardiac hypertrophy in rats
    • Balakumar P, Singh M, (2006) The possible role of caspase-3 in pathological and physiological cardiac hypertrophy in rats. Basic Clin Pharmacol Toxicol 99: 418-424.
    • (2006) Basic Clin Pharmacol Toxicol , vol.99 , pp. 418-424
    • Balakumar, P.1    Singh, M.2
  • 22
    • 85047694494 scopus 로고    scopus 로고
    • A mechanistic role for cardiac myocyte apoptosis in heart failure
    • Wencker D, Chandra M, Nguyen K, Miao W, Garantziotis S, et al. (2003) A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest 111: 1497-1504.
    • (2003) J Clin Invest , vol.111 , pp. 1497-1504
    • Wencker, D.1    Chandra, M.2    Nguyen, K.3    Miao, W.4    Garantziotis, S.5
  • 23
    • 0035997256 scopus 로고    scopus 로고
    • Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha
    • Aikawa R, Nitta-Komatsubara Y, Kudoh S, Takano H, Nagai T, et al. (2002) Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha. Cytokine 18: 179-183.
    • (2002) Cytokine , vol.18 , pp. 179-183
    • Aikawa, R.1    Nitta-Komatsubara, Y.2    Kudoh, S.3    Takano, H.4    Nagai, T.5
  • 24
    • 34347244963 scopus 로고    scopus 로고
    • Rapamycin prevents thyroid hormone-induced cardiac hypertrophy
    • Kuzman JA, O'Connell TD, Gerdes AM, (2007) Rapamycin prevents thyroid hormone-induced cardiac hypertrophy. Endocrinology 148: 3477-3484.
    • (2007) Endocrinology , vol.148 , pp. 3477-3484
    • Kuzman, J.A.1    O'Connell, T.D.2    Gerdes, A.M.3
  • 25
    • 0033597951 scopus 로고    scopus 로고
    • Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro
    • Siwik DA, Tzortzis JD, Pimental DR, Chang DL, Pagano PJ, et al. (1999) Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro. Circ Res 85: 147-153.
    • (1999) Circ Res , vol.85 , pp. 147-153
    • Siwik, D.A.1    Tzortzis, J.D.2    Pimental, D.R.3    Chang, D.L.4    Pagano, P.J.5
  • 26
    • 0035980171 scopus 로고    scopus 로고
    • Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes
    • Pimentel DR, Amin JK, Xiao L, Miller T, Viereck J, et al. (2001) Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ Res 89: 453-460.
    • (2001) Circ Res , vol.89 , pp. 453-460
    • Pimentel, D.R.1    Amin, J.K.2    Xiao, L.3    Miller, T.4    Viereck, J.5
  • 27
    • 57749086758 scopus 로고    scopus 로고
    • The role of redox signaling in cardiac hypertrophy induced by experimental hyperthyroidism
    • Araujo AS, Schenkel P, Enzveiler AT, Fernandes TR, Partata WA, et al. (2008) The role of redox signaling in cardiac hypertrophy induced by experimental hyperthyroidism. J Mol Endocrinol 41: 423-430.
    • (2008) J Mol Endocrinol , vol.41 , pp. 423-430
    • Araujo, A.S.1    Schenkel, P.2    Enzveiler, A.T.3    Fernandes, T.R.4    Partata, W.A.5
  • 28
    • 0015737673 scopus 로고
    • Effect of age on thyroxin-induced cardiac hypertrophy in mice
    • Florini JR, Saito Y, Manowitz EJ, (1973) Effect of age on thyroxin-induced cardiac hypertrophy in mice. J Gerontol 28: 293-297.
    • (1973) J Gerontol , vol.28 , pp. 293-297
    • Florini, J.R.1    Saito, Y.2    Manowitz, E.J.3
  • 32
    • 85047691556 scopus 로고    scopus 로고
    • Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy
    • Yamamoto S, Yang G, Zablocki D, Liu J, Hong C, et al. (2003) Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J Clin Invest 111: 1463-1474.
    • (2003) J Clin Invest , vol.111 , pp. 1463-1474
    • Yamamoto, S.1    Yang, G.2    Zablocki, D.3    Liu, J.4    Hong, C.5
  • 33
    • 10044261073 scopus 로고    scopus 로고
    • P38 alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload
    • Nishida K, Yamaguchi O, Hirotani S, Hikoso S, Higuchi Y, (2004) P38 alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol Cell Biol 24: 10611-10620.
    • (2004) Mol Cell Biol , vol.24 , pp. 10611-10620
    • Nishida, K.1    Yamaguchi, O.2    Hirotani, S.3    Hikoso, S.4    Higuchi, Y.5
  • 34
    • 0032102257 scopus 로고    scopus 로고
    • Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart
    • Fentzke RC, Korcarz CE, Lang RM, Lin H, Leiden JM, (1998) Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart. J Clin Invest 101: 2415-2426.
    • (1998) J Clin Invest , vol.101 , pp. 2415-2426
    • Fentzke, R.C.1    Korcarz, C.E.2    Lang, R.M.3    Lin, H.4    Leiden, J.M.5
  • 35
    • 69449085505 scopus 로고    scopus 로고
    • Dilated form of endocardial fibroelastosis as a result of deficiency in respiratory-chain complexes I and IV
    • Corradi D, Tchana B, Miller D, Manotti L, Maestri R, et al. (2009) Dilated form of endocardial fibroelastosis as a result of deficiency in respiratory-chain complexes I and IV. Circulation 120: e38-40.
    • (2009) Circulation , vol.120
    • Corradi, D.1    Tchana, B.2    Miller, D.3    Manotti, L.4    Maestri, R.5
  • 36
    • 8844261202 scopus 로고    scopus 로고
    • Regulation of caspase-3 and Fas in pressure overload-induced left ventricular dysfunction
    • Philipp S, Pagel I, Höhnel K, Lutz J, Buttgereit J, et al. (2004) Regulation of caspase-3 and Fas in pressure overload-induced left ventricular dysfunction. Eur J Heart Fail 6: 845-851.
    • (2004) Eur J Heart Fail , vol.6 , pp. 845-851
    • Philipp, S.1    Pagel, I.2    Höhnel, K.3    Lutz, J.4    Buttgereit, J.5
  • 37
    • 0035015260 scopus 로고    scopus 로고
    • Contribution of ventricular remodeling to pathogenesis of heart failure in rats
    • Brower GL, Janicki JS, (2001) Contribution of ventricular remodeling to pathogenesis of heart failure in rats. Am J Physiol Heart Circ Physiol 280: H674-H683.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Brower, G.L.1    Janicki, J.S.2
  • 38
    • 0027483722 scopus 로고
    • Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart
    • Yokoyama T, Vaca L, Rossen RD, Durante W, Hazarika P, et al. (1993) Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart. J Clin Invest 92: 2303-2312.
    • (1993) J Clin Invest , vol.92 , pp. 2303-2312
    • Yokoyama, T.1    Vaca, L.2    Rossen, R.D.3    Durante, W.4    Hazarika, P.5
  • 39
    • 31344463424 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion
    • Lu X, Hamilton JA, Shen J, Pang T, Jones DL, et al. (2006) Role of tumor necrosis factor-alpha in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion. Crit Care Med 34: 484-491.
    • (2006) Crit Care Med , vol.34 , pp. 484-491
    • Lu, X.1    Hamilton, J.A.2    Shen, J.3    Pang, T.4    Jones, D.L.5
  • 40
    • 18344384146 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced caspase activation mediates endotoxin-related cardiac dysfunction
    • Carlson DL, Willis MS, White DJ, Horton JW, Giroir BP, (2005) Tumor necrosis factor-alpha-induced caspase activation mediates endotoxin-related cardiac dysfunction. Crit Care Med 33: 1021-1028.
    • (2005) Crit Care Med , vol.33 , pp. 1021-1028
    • Carlson, D.L.1    Willis, M.S.2    White, D.J.3    Horton, J.W.4    Giroir, B.P.5
  • 41
    • 78650170566 scopus 로고    scopus 로고
    • Redox regulation of myocardial ERK 1/2 phosphorylation in experimental hyperthyroidism: role of thioredoxin-peroxiredoxin system
    • Araujo AS, Fernandes T, Ribeiro MF, Khaper N, Belló-Klein A, (2010) Redox regulation of myocardial ERK 1/2 phosphorylation in experimental hyperthyroidism: role of thioredoxin-peroxiredoxin system. J Cardiovasc Pharmacol 56: 513-517.
    • (2010) J Cardiovasc Pharmacol , vol.56 , pp. 513-517
    • Araujo, A.S.1    Fernandes, T.2    Ribeiro, M.F.3    Khaper, N.4    Belló-Klein, A.5
  • 42
    • 0036097632 scopus 로고    scopus 로고
    • Reciprocal modulation of mitogen-activated protein kinases and mitogen-activated protein kinase phosphatase 1 and 2 in failing human myocardium
    • Communal C, Colucci WS, Remondino A, Sawyer DB, Port JD, et al. (2002) Reciprocal modulation of mitogen-activated protein kinases and mitogen-activated protein kinase phosphatase 1 and 2 in failing human myocardium. J Card Fail 8: 86-92.
    • (2002) J Card Fail , vol.8 , pp. 86-92
    • Communal, C.1    Colucci, W.S.2    Remondino, A.3    Sawyer, D.B.4    Port, J.D.5
  • 43
    • 34248198298 scopus 로고    scopus 로고
    • Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy
    • Muchir A, Pavlidis P, Decostre V, Herron AJ, Arimura T, et al. (2007) Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy. J Clin Invest 117: 1282-1293.
    • (2007) J Clin Invest , vol.117 , pp. 1282-1293
    • Muchir, A.1    Pavlidis, P.2    Decostre, V.3    Herron, A.J.4    Arimura, T.5
  • 44
    • 33845598077 scopus 로고    scopus 로고
    • p38 Kinase rescues failing myocardium after myocardial infarction: evidence for angiogenic and anti-apoptotic mechanisms
    • Tenhunen O, Soini Y, Ilves M, Rysä J, Tuukkanen J, et al. (2006) p38 Kinase rescues failing myocardium after myocardial infarction: evidence for angiogenic and anti-apoptotic mechanisms. FASEB J 20: E1276-E1286.
    • (2006) FASEB J , vol.20
    • Tenhunen, O.1    Soini, Y.2    Ilves, M.3    Rysä, J.4    Tuukkanen, J.5
  • 45
    • 33748588705 scopus 로고    scopus 로고
    • Increased ERK activation and decreased MKP-1 expression in human myocardium with congestive heart failure
    • Dong Y, Gao D, Chen L, Lin R, Conte JV, et al. (2006) Increased ERK activation and decreased MKP-1 expression in human myocardium with congestive heart failure. J Cardiothorac Ren Res 1: 123-130.
    • (2006) J Cardiothorac Ren Res , vol.1 , pp. 123-130
    • Dong, Y.1    Gao, D.2    Chen, L.3    Lin, R.4    Conte, J.V.5
  • 46
    • 0034925481 scopus 로고    scopus 로고
    • Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart
    • Lemke LE, Bloem LJ, Fouts R, Esterman M, Sandusky G, et al. (2001) Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart. J Mol Cell Cardiol 33: 1527-1540.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1527-1540
    • Lemke, L.E.1    Bloem, L.J.2    Fouts, R.3    Esterman, M.4    Sandusky, G.5
  • 47
    • 33751190327 scopus 로고    scopus 로고
    • A death-promoting role for extracellular signal-regulated kinase
    • Zhuang S, Schnellmann RG, (2006) A death-promoting role for extracellular signal-regulated kinase. J Pharmacol Exp Ther 319: 991-997.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 991-997
    • Zhuang, S.1    Schnellmann, R.G.2
  • 48
    • 79959925200 scopus 로고    scopus 로고
    • Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling
    • Worou ME, Belmokhtar K, Bonnet P, Vourc'h P, Machet MC, et al. (2011) Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling. Cardiovasc Res 91: 320-329.
    • (2011) Cardiovasc Res , vol.91 , pp. 320-329
    • Worou, M.E.1    Belmokhtar, K.2    Bonnet, P.3    Vourc'h, P.4    Machet, M.C.5
  • 49
    • 0037176966 scopus 로고    scopus 로고
    • Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats
    • Yaoita H, Sakabe A, Maehara K, Maruyama Y, (2002) Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. Circulation 105: 975-980.
    • (2002) Circulation , vol.105 , pp. 975-980
    • Yaoita, H.1    Sakabe, A.2    Maehara, K.3    Maruyama, Y.4
  • 50
    • 77954145158 scopus 로고    scopus 로고
    • Protective effect of carvedilol on daunorubicin-induced cardiotoxicity and nephrotoxicity in rats
    • Arozal W, Watanabe K, Veeraveedu PT, Ma M, Thandavarayan RA, et al. (2010) Protective effect of carvedilol on daunorubicin-induced cardiotoxicity and nephrotoxicity in rats. Toxicology 274: 18-26.
    • (2010) Toxicology , vol.274 , pp. 18-26
    • Arozal, W.1    Watanabe, K.2    Veeraveedu, P.T.3    Ma, M.4    Thandavarayan, R.A.5
  • 51
    • 31344455023 scopus 로고    scopus 로고
    • Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure
    • Ichihara S, Noda A, Nagata K, Obata K, Xu J, et al. (2006) Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. Cardiovasc Res 69: 726-735.
    • (2006) Cardiovasc Res , vol.69 , pp. 726-735
    • Ichihara, S.1    Noda, A.2    Nagata, K.3    Obata, K.4    Xu, J.5
  • 52
    • 46549083150 scopus 로고    scopus 로고
    • Pravastatin attenuates carboplatin-induced cardiotoxicity via inhibition of oxidative stress associated apoptosis
    • Cheng CF, Juan SH, Chen JJ, Chao YC, Chen HH, et al. (2008) Pravastatin attenuates carboplatin-induced cardiotoxicity via inhibition of oxidative stress associated apoptosis. Apoptosis 13: 883-894.
    • (2008) Apoptosis , vol.13 , pp. 883-894
    • Cheng, C.F.1    Juan, S.H.2    Chen, J.J.3    Chao, Y.C.4    Chen, H.H.5
  • 53
    • 58149176611 scopus 로고    scopus 로고
    • Comparison of losartan and carvedilol on attenuating inflammatory and oxidative response and preserving energytranscription factors and left ventricular function in dilated cardiomyopathy rats. Int
    • Chua S, Sheu JJ, Chang LT, Lee FY, Wu CJ, et al. (2008) Comparison of losartan and carvedilol on attenuating inflammatory and oxidative response and preserving energytranscription factors and left ventricular function in dilated cardiomyopathy rats. Int. Heart J 49: 605-619.
    • (2008) Heart J , vol.49 , pp. 605-619
    • Chua, S.1    Sheu, J.J.2    Chang, L.T.3    Lee, F.Y.4    Wu, C.J.5
  • 54
    • 33746488189 scopus 로고    scopus 로고
    • Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction
    • Li B, Liao YH, Cheng X, Ge H, Guo H, et al. (2006) Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction. Int J Cardiol 111: 247-255.
    • (2006) Int J Cardiol , vol.111 , pp. 247-255
    • Li, B.1    Liao, Y.H.2    Cheng, X.3    Ge, H.4    Guo, H.5
  • 55
    • 0036895484 scopus 로고    scopus 로고
    • Effects of carvedilol on left ventricular remodeling and systolic function in elderly patients with heart failure
    • Palazzuoli A, Bruni F, Puccetti L, Pastorelli M, Angori P, et al. (2002) Effects of carvedilol on left ventricular remodeling and systolic function in elderly patients with heart failure. Eur J Heart Fail 4: 765-770.
    • (2002) Eur J Heart Fail , vol.4 , pp. 765-770
    • Palazzuoli, A.1    Bruni, F.2    Puccetti, L.3    Pastorelli, M.4    Angori, P.5
  • 56
    • 58149400641 scopus 로고    scopus 로고
    • Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress
    • Zhao H, Liao Y, Minamino T, Asano Y, Asakura M, et al. (2008) Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress. Hypertens Res 31: 1977-1987.
    • (2008) Hypertens Res , vol.31 , pp. 1977-1987
    • Zhao, H.1    Liao, Y.2    Minamino, T.3    Asano, Y.4    Asakura, M.5
  • 57
    • 80052243532 scopus 로고    scopus 로고
    • Beta-Blockers and Oxidative Stress in Patients with Heart Failure
    • Nakamura K, Murakami M, Miura D, Yunoki K, Enko K, et al. (2011) Beta-Blockers and Oxidative Stress in Patients with Heart Failure. Pharmaceuticals 4: 1088-1100.
    • (2011) Pharmaceuticals , vol.4 , pp. 1088-1100
    • Nakamura, K.1    Murakami, M.2    Miura, D.3    Yunoki, K.4    Enko, K.5
  • 58
    • 38349132755 scopus 로고    scopus 로고
    • Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice
    • Xu Z, Okamoto H, Akino M, Onozuka H, Matsui Y, et al. (2008) Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice. J Cardiovasc Pharmacol 51: 62-70.
    • (2008) J Cardiovasc Pharmacol , vol.51 , pp. 62-70
    • Xu, Z.1    Okamoto, H.2    Akino, M.3    Onozuka, H.4    Matsui, Y.5
  • 59
    • 76849102108 scopus 로고    scopus 로고
    • Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy
    • Ojamaa K, (2010) Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy. Vascul Pharmacol 52: 113-119.
    • (2010) Vascul Pharmacol , vol.52 , pp. 113-119
    • Ojamaa, K.1
  • 60
    • 0018220385 scopus 로고
    • Normal and hypertrophic growth of the rat heart: changes in cell dimensions and number
    • Korecky B, Rakusan K, (1978) Normal and hypertrophic growth of the rat heart: changes in cell dimensions and number. Am J Physiol 234: H123-H128.
    • (1978) Am J Physiol , vol.234
    • Korecky, B.1    Rakusan, K.2
  • 61
    • 77956946043 scopus 로고    scopus 로고
    • Smaller cardiac cell size and reduced extra-cellular collagen might be beneficial for hearts of Ames dwarf mice
    • Helms SA, Azhar G, Zuo C, Theus SA, Bartke A, et al. (2010) Smaller cardiac cell size and reduced extra-cellular collagen might be beneficial for hearts of Ames dwarf mice. Int J Biol Sci 6: 475-490.
    • (2010) Int J Biol Sci , vol.6 , pp. 475-490
    • Helms, S.A.1    Azhar, G.2    Zuo, C.3    Theus, S.A.4    Bartke, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.