Prime causes of rapid cardiomyocyte death during reperfusion

Annals of Thoracic Surgery

Volumn 68, Issue 5, 1999, Pages 1913-1919

  Piper, Hans Michael ^a   García Dorado, David ^b  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CONFERENCE PAPER; HEART MUSCLE CELL; HUMAN; MECHANICAL STRESS; OSMOLALITY; PH; PRIORITY JOURNAL; REPERFUSION INJURY;

ACID-BASE EQUILIBRIUM; ANIMALS; CALCIUM; CELL DEATH; HUMANS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; WATER-ELECTROLYTE BALANCE;

EID: 0345201627     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(99)01025-5     Document Type: Conference Paper

References (25)

1. Przyklenk K, ed. Lethal myocardial reperfusion injury [Special issue]. J Thromb Thrombolysis 1997;4(1).
2. Ferrari R., Hearse D.J. Reperfusion injury does it exist and does it have clinical relevance? J Thromb Thrombolysis. 4:1997;25-34.
3. Downey J.M., Yellon D.M. Do free radicals contribute to myocardial cell death during ischemia-reperfusion? Yellon C.M., Jennings R.B. Myocardial protection the pathophysiology of reperfusion and reperfusion injury . 1992;35-57 Raven, New York.
4. Hearse D.J., Humphrey S.M., Chain E.B. Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart a study of myocardial enzyme release . J Mol Cell Cardiol. 5:1973;395-407.
5. Ganote C.E., Vander Heide R.S. Importance of mechanical factors in ischemic and reperfusion injury. Piper H.M. Pathophysiology of severe ischemic myocardial injury. 1990;337-355 Kluwer, Dordrecht.
6. 2+ overload. Am J Physiol. 263:1992;H1262-H1269.
7. 2+ control in reoxygenated cardiomyocytes. Am J Physiol. 267:1994;H506-H513.
8. Siegmund B., Koop A., Klietz T., et al. Sarcolemmal integrity and metabolic competence of cardiomyocytes under anoxia-reoxygenation. Am J Physiol. 258:1990;H285-H291.
9. Siegmund B., Klietz T., Schwartz P., et al. Temporary contractile blockade prevents hypercontracture in anoxic-reoxygenated cardiomyocytes. Am J Physiol. 260:1991;H426-H435.
10. Schlüter K.D., Schwartz P., Siegmund B., et al. Prevention of the oxygen paradox in hypoxic-reoxygenated hearts. Am J Physiol. 261:1991;H416-H432.
11. García-Dorado D., Théroux P., Duran J.M., et al. Selective inhibition of the contractile apparatus a new approach to modification of infarct size, infarct composition, and infarct geometry during coronary artery occlusion and reperfusion . Circulation. 85:1992;1160-1174.
12. Schlack W., Uebing A., Schäfer M., et al. Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart. Pflügers Arch. 428:1994;134-141.
13. Habazettl H., Palmisano B.W., Bosnjak Z.J., et al. Initial reperfusion with 2,3 butanedione monoxime is better than hyperkalemic reperfusion after cardioplegic arrest in isolated guinea pig hearts. Eur J Cardiothorac Surg. 10:1996;897-904.
14. Siegmund B., Schlack W., Piper H.M. Halothane protects cardiomyocytes against reoxygenation-induced hypercontracture. Circulation. 96:1997;4372-4379.
15. Ladilov Y.V., Siegmund B., Piper H.M. Simulated ischemia increases the susceptibility of rat cardiomyocytes to hypercontracture. Circ Res. 80:1997;69-75.
16. Schlack W., Hollmann M., Stunneck J., et al. Effect of halothane on myocardial reoxygenation injury in the isolated rat heart. Br J Anaesth. 76:1996;860-867.
17. Preckel B., Schlack W., Comfère T., et al. Effects of inhalational anaesthetics on myocardial reperfusion injury in vivo. Pflügers Arch. 433:(Suppl 6):1997;R15.
18. + exchange in ischemia-reperfusion. Basic Res Cardiol. 91:1996;191-202.
19. + exchange. Am J Physiol. 268:1995;H1531-H1539.
20. + exchange occurring during hypoxia in the genesis of reoxygenation-induced myocardial oedema. J Mol Cell Cardiol. 29:1997;1167-1175.
21. Ruiz-Meana M., García-Dorado D., González M.A., et al. Effect of osmotic stress on sarcolemmal integrity of isolated cardiomyocytes following transient metabolic inhibition. Cardiovasc Res. 30:1995;64-69.
22. García-Dorado D., Théroux P., Muñoz R., et al. Favorable effects of hyperosmotic reperfusion on myocardial edema and infarct size. Am J Physiol. 262:1992;H17-H22.
23. Schlüter K.D., Jakob G., Ruiz-Meana M., et al. Protection of reoxygenated cardiomyocytes against osmotic fragility by NO donors. Am J Physiol. 271:1996;H428-H434.
24. Solares J., García-Dorado D., Oliveras J., et al. Contraction band necrosis at the lateral borders of the area at risk in reperfused infarcts. Observations in a pig model of in situ coronary occlusion. Virchows Arch. 426:1995;393-399.
25. García-Dorado D., Inserte J., Ruiz-Meana M., et al. Gap junction uncoupler heptanol prevents cell-to-cell progression of hypercontracture and limits necrosis during myocardial reperfusion. Circulation. 96:1997;3579-3586.