메뉴 건너뛰기




Volumn 8, Issue , 2010, Pages

Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ARGINYLGLYCYLASPARTYLSERINE; COFILIN; COLLAGEN; PADGEM PROTEIN; RAC1 PROTEIN; ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; AMINOQUINOLINE DERIVATIVE; ISOENZYME; PROSTAGLANDIN SYNTHASE; PYRIMIDINE DERIVATIVE; RAC1 PROTEIN, HUMAN; TARTRATE-RESISTANT ACID PHOSPHATASE;

EID: 78649686720     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-8-128     Document Type: Article
Times cited : (34)

References (25)
  • 1
    • 0028240452 scopus 로고
    • Characterization of the relative thrombogenicity of atherosclerotic plaque components: implications for consequences of plaque rupture
    • 10.1016/0735-1097(94)90657-2, 8195515
    • Fernandez-Ortiz A, Badimon JJ, Falk E, Fuster V, Meyer B, Mailhac A, Weng D, Shah PK, Badimon L. Characterization of the relative thrombogenicity of atherosclerotic plaque components: implications for consequences of plaque rupture. J Am Coll Cardiol 1994, 23:1562-1569. 10.1016/0735-1097(94)90657-2, 8195515.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1562-1569
    • Fernandez-Ortiz, A.1    Badimon, J.J.2    Falk, E.3    Fuster, V.4    Meyer, B.5    Mailhac, A.6    Weng, D.7    Shah, P.K.8    Badimon, L.9
  • 4
    • 0043020630 scopus 로고    scopus 로고
    • Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques
    • 10.1161/01.CIR.0000083715.37658.C4, 12885756
    • Rother E, Brandl R, Baker DL, Goyal P, Gebhard H, Tigyi G, Siess W. Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques. Circulation 2003, 108:741-747. 10.1161/01.CIR.0000083715.37658.C4, 12885756.
    • (2003) Circulation , vol.108 , pp. 741-747
    • Rother, E.1    Brandl, R.2    Baker, D.L.3    Goyal, P.4    Gebhard, H.5    Tigyi, G.6    Siess, W.7
  • 7
    • 0033199252 scopus 로고    scopus 로고
    • Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets
    • Bauer M, Retzer M, Wilde JI, Maschberger P, Essler M, Aepfelbacher M, Watson SP, Siess W. Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets. Blood 1999, 94:1665-1672.
    • (1999) Blood , vol.94 , pp. 1665-1672
    • Bauer, M.1    Retzer, M.2    Wilde, J.I.3    Maschberger, P.4    Essler, M.5    Aepfelbacher, M.6    Watson, S.P.7    Siess, W.8
  • 8
    • 0033593667 scopus 로고    scopus 로고
    • Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets
    • 10.1083/jcb.144.4.745, 2132941, 10037795
    • Klages B, Brandt U, Simon MI, Schultz G, Offermanns S. Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets. J Cell Biol 1999, 144:745-754. 10.1083/jcb.144.4.745, 2132941, 10037795.
    • (1999) J Cell Biol , vol.144 , pp. 745-754
    • Klages, B.1    Brandt, U.2    Simon, M.I.3    Schultz, G.4    Offermanns, S.5
  • 10
    • 0035798144 scopus 로고    scopus 로고
    • Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets
    • 10.1016/S0014-5793(01)02984-2, 11696351
    • Soulet C, Gendreau S, Missy K, Benard V, Plantavid M, Payrastre B. Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets. FEBS Lett 2001, 507:253-258. 10.1016/S0014-5793(01)02984-2, 11696351.
    • (2001) FEBS Lett , vol.507 , pp. 253-258
    • Soulet, C.1    Gendreau, S.2    Missy, K.3    Benard, V.4    Plantavid, M.5    Payrastre, B.6
  • 11
    • 0035930528 scopus 로고    scopus 로고
    • Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides
    • Gratacap MP, Payrastre B, Nieswandt B, Offermanns S. Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides. J Biol Chem 2001, 276:47906-47913.
    • (2001) J Biol Chem , vol.276 , pp. 47906-47913
    • Gratacap, M.P.1    Payrastre, B.2    Nieswandt, B.3    Offermanns, S.4
  • 12
    • 34447648178 scopus 로고    scopus 로고
    • Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation
    • 10.1111/j.1538-7836.2007.02646.x, 17663742
    • Akbar H, Kim J, Funk K, Cancelas JA, Shang X, Chen L, Johnson JF, Williams DA, Zheng Y. Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation. J Thromb Haemost 2007, 5:1747-1755. 10.1111/j.1538-7836.2007.02646.x, 17663742.
    • (2007) J Thromb Haemost , vol.5 , pp. 1747-1755
    • Akbar, H.1    Kim, J.2    Funk, K.3    Cancelas, J.A.4    Shang, X.5    Chen, L.6    Johnson, J.F.7    Williams, D.A.8    Zheng, Y.9
  • 13
    • 67651091672 scopus 로고    scopus 로고
    • Unraveling a novel Rac1-mediated signaling pathway that regulates cofilin dephosphorylation and secretion in thrombin-stimulated platelets
    • 10.1182/blood-2008-10-183582, 19429871
    • Pandey D, Goyal P, Dwivedi S, Siess W. Unraveling a novel Rac1-mediated signaling pathway that regulates cofilin dephosphorylation and secretion in thrombin-stimulated platelets. Blood 2009, 114:415-424. 10.1182/blood-2008-10-183582, 19429871.
    • (2009) Blood , vol.114 , pp. 415-424
    • Pandey, D.1    Goyal, P.2    Dwivedi, S.3    Siess, W.4
  • 15
    • 2442664118 scopus 로고    scopus 로고
    • Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
    • 10.1073/pnas.0307512101, 419655, 15128949
    • Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci USA 2004, 101:7618-7623. 10.1073/pnas.0307512101, 419655, 15128949.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7618-7623
    • Gao, Y.1    Dickerson, J.B.2    Guo, F.3    Zheng, J.4    Zheng, Y.5
  • 16
    • 0030778796 scopus 로고    scopus 로고
    • Topographic analysis of proliferative activity in carotid endarterectomy specimens by immunocytochemical detection of the cell cycle-related antigen Ki-67
    • Brandl R, Richter T, Haug K, Wilhelm MG, Maurer PC, Nathrath W. Topographic analysis of proliferative activity in carotid endarterectomy specimens by immunocytochemical detection of the cell cycle-related antigen Ki-67. Circulation 1997, 96:3360-3368.
    • (1997) Circulation , vol.96 , pp. 3360-3368
    • Brandl, R.1    Richter, T.2    Haug, K.3    Wilhelm, M.G.4    Maurer, P.C.5    Nathrath, W.6
  • 17
    • 33947322186 scopus 로고    scopus 로고
    • Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques
    • Penz SM, Reininger AJ, Toth O, Deckmyn H, Brandl R, Siess W. Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques. Thromb Haemost 2007, 97:435-443.
    • (2007) Thromb Haemost , vol.97 , pp. 435-443
    • Penz, S.M.1    Reininger, A.J.2    Toth, O.3    Deckmyn, H.4    Brandl, R.5    Siess, W.6
  • 18
    • 33845358942 scopus 로고    scopus 로고
    • Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood
    • Toth O, Calatzis A, Penz S, Losonczy H, Siess W. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost 2006, 96:781-788.
    • (2006) Thromb Haemost , vol.96 , pp. 781-788
    • Toth, O.1    Calatzis, A.2    Penz, S.3    Losonczy, H.4    Siess, W.5
  • 19
    • 0018614306 scopus 로고
    • Direct measurement of platelet secretion in whole blood
    • 10.1016/0049-3848(79)90081-1, 515999
    • Ingerman CM, Smith JB, Silver MJ. Direct measurement of platelet secretion in whole blood. Thromb Res 1979, 16:335-344. 10.1016/0049-3848(79)90081-1, 515999.
    • (1979) Thromb Res , vol.16 , pp. 335-344
    • Ingerman, C.M.1    Smith, J.B.2    Silver, M.J.3
  • 20
    • 0021668717 scopus 로고
    • Effect of prostacyclin (epoprostenol) on the aggregation of human platelets in whole blood in vitro
    • Saniabadi AR, Lowe GD, Belch JJ, Barbenel JC, Forbes CD. Effect of prostacyclin (epoprostenol) on the aggregation of human platelets in whole blood in vitro. Haemostasis 1984, 14:487-494.
    • (1984) Haemostasis , vol.14 , pp. 487-494
    • Saniabadi, A.R.1    Lowe, G.D.2    Belch, J.J.3    Barbenel, J.C.4    Forbes, C.D.5
  • 21
    • 0034142240 scopus 로고    scopus 로고
    • Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor
    • Azim AC, Barkalow K, Chou J, Hartwig JH. Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor. Blood 2000, 95:959-964.
    • (2000) Blood , vol.95 , pp. 959-964
    • Azim, A.C.1    Barkalow, K.2    Chou, J.3    Hartwig, J.H.4
  • 22
    • 28444493640 scopus 로고    scopus 로고
    • A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation
    • 10.1111/j.1538-7836.2005.01588.x, 16194206
    • Soulet C, Hechler B, Gratacap MP, Plantavid M, Offermanns S, Gachet C, Payrastre B. A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation. J Thromb Haemost 2005, 3:2296-2306. 10.1111/j.1538-7836.2005.01588.x, 16194206.
    • (2005) J Thromb Haemost , vol.3 , pp. 2296-2306
    • Soulet, C.1    Hechler, B.2    Gratacap, M.P.3    Plantavid, M.4    Offermanns, S.5    Gachet, C.6    Payrastre, B.7
  • 23
    • 0037512367 scopus 로고    scopus 로고
    • The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation
    • Cho MJ, Liu J, Pestina TI, Steward SA, Thomas DW, Coffman TM, Wang D, Jackson CW, Gartner TK. The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation. Blood 2003, 101:26462651.
    • (2003) Blood , vol.101 , pp. 26462651
    • Cho, M.J.1    Liu, J.2    Pestina, T.I.3    Steward, S.A.4    Thomas, D.W.5    Coffman, T.M.6    Wang, D.7    Jackson, C.W.8    Gartner, T.K.9
  • 24
    • 0027161237 scopus 로고
    • Aspirin does not inhibit adenosine diphosphate-induced platelet alpha-granule release
    • Rinder CS, Student LA, Bonan JL, Rinder HM, Smith BR. Aspirin does not inhibit adenosine diphosphate-induced platelet alpha-granule release. Blood 1993, 82:505-512.
    • (1993) Blood , vol.82 , pp. 505-512
    • Rinder, C.S.1    Student, L.A.2    Bonan, J.L.3    Rinder, H.M.4    Smith, B.R.5
  • 25
    • 0024532116 scopus 로고
    • Molecular mechanisms of platelet activation
    • Siess W. Molecular mechanisms of platelet activation. Physiol Rev 1989, 69:58-178.
    • (1989) Physiol Rev , vol.69 , pp. 58-178
    • Siess, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.