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Volumn 34, Issue 4, 2013, Pages 1184-1198

Spatial behavior and seizure-induced changes in c-fos mRNA expression in young and old rats

Author keywords

Aging; Immediate early genes; Learning and memory; Seizures; Synaptic plasticity; Transcription

Indexed keywords

MESSENGER RNA; PROTEIN C FOS;

EID: 84872312835     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.10.017     Document Type: Article
Times cited : (20)

References (73)
  • 1
    • 0026306278 scopus 로고
    • The role of immediate early genes in the stabilization of long-term potentiation
    • Abraham W.C., Dragunow M., Tate W.P. The role of immediate early genes in the stabilization of long-term potentiation. Mol. Neurobiol. 1991, 5:297-314.
    • (1991) Mol. Neurobiol. , vol.5 , pp. 297-314
    • Abraham, W.C.1    Dragunow, M.2    Tate, W.P.3
  • 3
    • 0344585051 scopus 로고    scopus 로고
    • Properties and mechanisms of LTP maintenance
    • Abraham W.C., Williams J.M. Properties and mechanisms of LTP maintenance. Neuroscientist 2003, 9:463-474.
    • (2003) Neuroscientist , vol.9 , pp. 463-474
    • Abraham, W.C.1    Williams, J.M.2
  • 4
    • 0034282068 scopus 로고    scopus 로고
    • LTP induction threshold change in old rats at the perforant path-granule cell synapse
    • Barnes C.A., Rao G., Houston F.P. LTP induction threshold change in old rats at the perforant path-granule cell synapse. Neurobiol. Aging 2000, 21:613-620.
    • (2000) Neurobiol. Aging , vol.21 , pp. 613-620
    • Barnes, C.A.1    Rao, G.2    Houston, F.P.3
  • 5
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment
    • Blalock E.M., Chen K.C., Sharrow K., Herman J.P., Porter N.M., Foster T.C., Landfield P.W. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J. Neurosci. 2003, 23:3807-3819.
    • (2003) J. Neurosci. , vol.23 , pp. 3807-3819
    • Blalock, E.M.1    Chen, K.C.2    Sharrow, K.3    Herman, J.P.4    Porter, N.M.5    Foster, T.C.6    Landfield, P.W.7
  • 6
    • 56549084442 scopus 로고    scopus 로고
    • Local protein synthesis, actin dynamics, and LTP consolidation
    • Bramham C.R. Local protein synthesis, actin dynamics, and LTP consolidation. Curr. Opin. Neurobiol. 2008, 18:524-531.
    • (2008) Curr. Opin. Neurobiol. , vol.18 , pp. 524-531
    • Bramham, C.R.1
  • 7
    • 0345118873 scopus 로고    scopus 로고
    • Hippocampal CREB1 but not CREB2 is decreased in aged rats with spatial memory impairments
    • Brightwell J.J., Gallagher M., Colombo P.J. Hippocampal CREB1 but not CREB2 is decreased in aged rats with spatial memory impairments. Neurobiol. Learn. Mem. 2004, 81:19-26.
    • (2004) Neurobiol. Learn. Mem. , vol.81 , pp. 19-26
    • Brightwell, J.J.1    Gallagher, M.2    Colombo, P.J.3
  • 8
    • 0031873695 scopus 로고    scopus 로고
    • Effects of age on pilocarpine-induced c-fos expression in rat hippocampus and cortex
    • Bucci D.J., Rosen D.L., Gallagher M. Effects of age on pilocarpine-induced c-fos expression in rat hippocampus and cortex. Neurobiol. Aging 1998, 19:227-232.
    • (1998) Neurobiol. Aging , vol.19 , pp. 227-232
    • Bucci, D.J.1    Rosen, D.L.2    Gallagher, M.3
  • 9
    • 29244439038 scopus 로고    scopus 로고
    • Neural plasticity in the ageing brain
    • Burke S.N., Barnes C.A. Neural plasticity in the ageing brain. Nat. Rev. Neurosci. 2006, 7:30-40.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 30-40
    • Burke, S.N.1    Barnes, C.A.2
  • 11
    • 4444340185 scopus 로고    scopus 로고
    • 3D-catFISH: a system for automated quantitative three-dimensional compartmental analysis of temporal gene transcription activity imaged by fluorescence in situ hybridization
    • Chawla M.K., Lin G., Olson K., Vazdarjanova A., Burke S.N., McNaughton B.L., Worley P.F., Guzowski J.F., Roysam B., Barnes C.A. 3D-catFISH: a system for automated quantitative three-dimensional compartmental analysis of temporal gene transcription activity imaged by fluorescence in situ hybridization. J. Neurosci. Methods 2004, 139:13-24.
    • (2004) J. Neurosci. Methods , vol.139 , pp. 13-24
    • Chawla, M.K.1    Lin, G.2    Olson, K.3    Vazdarjanova, A.4    Burke, S.N.5    McNaughton, B.L.6    Worley, P.F.7    Guzowski, J.F.8    Roysam, B.9    Barnes, C.A.10
  • 12
    • 0026633067 scopus 로고
    • Seizure susceptibility in aged rats-pentylenetetrazol-induced seizures and amygdaloid kindling seizures [in Japanese]
    • Chiba S., Muneoka Y., Sato Y., Miyagishi T. Seizure susceptibility in aged rats-pentylenetetrazol-induced seizures and amygdaloid kindling seizures [in Japanese]. No To Shinkei 1992, 44:559-564.
    • (1992) No To Shinkei , vol.44 , pp. 559-564
    • Chiba, S.1    Muneoka, Y.2    Sato, Y.3    Miyagishi, T.4
  • 13
    • 0033743078 scopus 로고    scopus 로고
    • The genomic action potential
    • Clayton D.F. The genomic action potential. Neurobiol. Learn. Mem. 2000, 74:185-216.
    • (2000) Neurobiol. Learn. Mem. , vol.74 , pp. 185-216
    • Clayton, D.F.1
  • 14
    • 0025663462 scopus 로고
    • Rapid rise in transcription factor messenger RNAs in rat brain after electroshock induced seizures
    • Cole A.J., Abu-Shakra S., Saffen D.W., Baraban J.M., Worley P.W. Rapid rise in transcription factor messenger RNAs in rat brain after electroshock induced seizures. J. Neurochem. 1990, 55:1920-1927.
    • (1990) J. Neurochem. , vol.55 , pp. 1920-1927
    • Cole, A.J.1    Abu-Shakra, S.2    Saffen, D.W.3    Baraban, J.M.4    Worley, P.W.5
  • 15
    • 0024403534 scopus 로고
    • Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation
    • Cole A.J., Saffen D.W., Baraban J.M., Worley P.F. Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation. Nature 1989, 340:474-476.
    • (1989) Nature , vol.340 , pp. 474-476
    • Cole, A.J.1    Saffen, D.W.2    Baraban, J.M.3    Worley, P.F.4
  • 17
    • 0026331026 scopus 로고
    • Attenuation of Fos-like immunoreactivity induced by a single electroconvulsive shock in brains of aging mice
    • D'Costa A., Breese C.R., Boyd R.L., Booze R.M., Sonntag W.E. Attenuation of Fos-like immunoreactivity induced by a single electroconvulsive shock in brains of aging mice. Brain Res. 1991, 567:204-211.
    • (1991) Brain Res. , vol.567 , pp. 204-211
    • D'Costa, A.1    Breese, C.R.2    Boyd, R.L.3    Booze, R.M.4    Sonntag, W.E.5
  • 19
    • 0021611719 scopus 로고
    • Age-dependent deficits in spatial memory are related to impaired hippocampal kindling
    • de Toledo-Morrell L., Morrell F., Fleming S. Age-dependent deficits in spatial memory are related to impaired hippocampal kindling. Behav. Neurosci. 1984, 98:902-907.
    • (1984) Behav. Neurosci. , vol.98 , pp. 902-907
    • de Toledo-Morrell, L.1    Morrell, F.2    Fleming, S.3
  • 20
    • 0024371937 scopus 로고
    • Long-term potentiation and the induction of c-fos mRNA and proteins in the dentate gyrus of unanesthetized rats
    • Dragunow M., Abraham W.C., Goulding M., Mason S.E., Robertson H.A., Faull R.L. Long-term potentiation and the induction of c-fos mRNA and proteins in the dentate gyrus of unanesthetized rats. Neurosci. Lett. 1989, 101:274-280.
    • (1989) Neurosci. Lett. , vol.101 , pp. 274-280
    • Dragunow, M.1    Abraham, W.C.2    Goulding, M.3    Mason, S.E.4    Robertson, H.A.5    Faull, R.L.6
  • 21
    • 0023628516 scopus 로고
    • Generalized seizures induce c-fos protein(s) in mammalian neurons
    • Dragunow M., Robertson H.A. Generalized seizures induce c-fos protein(s) in mammalian neurons. Neurosci. Lett. 1987, 82:157-161.
    • (1987) Neurosci. Lett. , vol.82 , pp. 157-161
    • Dragunow, M.1    Robertson, H.A.2
  • 22
    • 0028612035 scopus 로고
    • Animal studies of electroconvulsive therapy: foundations for future research
    • Fochtmann L.J. Animal studies of electroconvulsive therapy: foundations for future research. Psychopharmacol. Bull. 1994, 30:321-444.
    • (1994) Psychopharmacol. Bull. , vol.30 , pp. 321-444
    • Fochtmann, L.J.1
  • 24
    • 0034213297 scopus 로고    scopus 로고
    • Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
    • Guzowski J.F., Lyford G.L., Stevenson G.D., Houston F.P., McGaugh J.L., Worley P.F., Barnes C.A. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J. Neurosci. 2000, 20:3993-4001.
    • (2000) J. Neurosci. , vol.20 , pp. 3993-4001
    • Guzowski, J.F.1    Lyford, G.L.2    Stevenson, G.D.3    Houston, F.P.4    McGaugh, J.L.5    Worley, P.F.6    Barnes, C.A.7
  • 25
    • 0033490104 scopus 로고    scopus 로고
    • Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles
    • Guzowski J.F., McNaughton B.L., Barnes C.A., Worley P.F. Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles. Nat. Neurosci. 1999, 2:1120-1124.
    • (1999) Nat. Neurosci. , vol.2 , pp. 1120-1124
    • Guzowski, J.F.1    McNaughton, B.L.2    Barnes, C.A.3    Worley, P.F.4
  • 28
    • 34548686085 scopus 로고    scopus 로고
    • Synaptic activity-induced global gene expression patterns in the dentate gyrus of adult behaving rats: induction of immunity-linked genes
    • Havik B., Rokke H., Dagyte G., Stavrum A.K., Bramham C.R., Steen V.M. Synaptic activity-induced global gene expression patterns in the dentate gyrus of adult behaving rats: induction of immunity-linked genes. Neuroscience 2007, 148:925-936.
    • (2007) Neuroscience , vol.148 , pp. 925-936
    • Havik, B.1    Rokke, H.2    Dagyte, G.3    Stavrum, A.K.4    Bramham, C.R.5    Steen, V.M.6
  • 29
    • 0032444348 scopus 로고    scopus 로고
    • Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
    • Herdegen T., Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev. 1998, 28:370-490.
    • (1998) Brain Res. Brain Res. Rev. , vol.28 , pp. 370-490
    • Herdegen, T.1    Leah, J.D.2
  • 31
    • 0027411298 scopus 로고
    • Differences in c-fos immunoreactivity due to age and mode of seizure induction
    • Jensen F.E., Firkusny I.R., Mower G.D. Differences in c-fos immunoreactivity due to age and mode of seizure induction. Brain Res. Mol. Brain Res. 1993, 17:185-193.
    • (1993) Brain Res. Mol. Brain Res. , vol.17 , pp. 185-193
    • Jensen, F.E.1    Firkusny, I.R.2    Mower, G.D.3
  • 32
    • 0024566999 scopus 로고
    • Elevated dynorphin in the hippocampal formation of aged rats: relation to cognitive impairment on a spatial learning task
    • Jiang H.-K., Owyang V., Hong J.-S., Gallagher M. Elevated dynorphin in the hippocampal formation of aged rats: relation to cognitive impairment on a spatial learning task. Proc. Natl. Acad. Sci. U. S. A. 1989, 86:2948-2951.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 2948-2951
    • Jiang, H.-K.1    Owyang, V.2    Hong, J.-S.3    Gallagher, M.4
  • 34
    • 0025542919 scopus 로고
    • C-fos protooncogene expression and neuronal plasticity
    • Kaczmarek L., Nikolajew E. c-fos protooncogene expression and neuronal plasticity. Acta Neurobiol. Exp. (Wars.) 1990, 50:173-179.
    • (1990) Acta Neurobiol. Exp. (Wars.) , vol.50 , pp. 173-179
    • Kaczmarek, L.1    Nikolajew, E.2
  • 35
    • 0030988498 scopus 로고    scopus 로고
    • Selective alteration of long-term potentiation-induced transcriptional response in hippocampus of aged, memory-impaired rats
    • Lanahan A., Lyford G., Stevenson G.S., Worley P.F., Barnes C.A. Selective alteration of long-term potentiation-induced transcriptional response in hippocampus of aged, memory-impaired rats. J. Neurosci. 1997, 17:2876-2885.
    • (1997) J. Neurosci. , vol.17 , pp. 2876-2885
    • Lanahan, A.1    Lyford, G.2    Stevenson, G.S.3    Worley, P.F.4    Barnes, C.A.5
  • 36
    • 0032123384 scopus 로고    scopus 로고
    • Immediate-early genes and synaptic function
    • Lanahan A., Worley P. Immediate-early genes and synaptic function. Neurobiol. Learn. Mem. 1998, 70:37-43.
    • (1998) Neurobiol. Learn. Mem. , vol.70 , pp. 37-43
    • Lanahan, A.1    Worley, P.2
  • 37
    • 13244256957 scopus 로고    scopus 로고
    • Hierarchical, model-based merging of multiple fragments for improved three-dimensional segmentation of nuclei
    • Lin G., Chawla M.K., Olson K., Guzowski J.F., Barnes C.A., Roysam B. Hierarchical, model-based merging of multiple fragments for improved three-dimensional segmentation of nuclei. Cytometry A 2005, 63:20-33.
    • (2005) Cytometry A , vol.63 , pp. 20-33
    • Lin, G.1    Chawla, M.K.2    Olson, K.3    Guzowski, J.F.4    Barnes, C.A.5    Roysam, B.6
  • 38
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 39
    • 70349663992 scopus 로고    scopus 로고
    • The function of activity-regulated genes in the nervous system
    • Loebrich S., Nedivi E. The function of activity-regulated genes in the nervous system. Physiol. Rev. 2009, 89:1079-1103.
    • (2009) Physiol. Rev. , vol.89 , pp. 1079-1103
    • Loebrich, S.1    Nedivi, E.2
  • 40
    • 0034161293 scopus 로고    scopus 로고
    • Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor
    • Magnusson K.R. Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor. J. Neurosci. 2000, 20:1666-1674.
    • (2000) J. Neurosci. , vol.20 , pp. 1666-1674
    • Magnusson, K.R.1
  • 42
    • 0023193514 scopus 로고
    • Mapping patterns of c-fos expression in the central nervous system after seizure
    • Morgan J.I., Cohen D.R., Hempstead J.L., Curran T. Mapping patterns of c-fos expression in the central nervous system after seizure. Science 1987, 237:192-197.
    • (1987) Science , vol.237 , pp. 192-197
    • Morgan, J.I.1    Cohen, D.R.2    Hempstead, J.L.3    Curran, T.4
  • 43
    • 0030698871 scopus 로고    scopus 로고
    • Life and death of neurons in the aging brain
    • Morrison J.H., Hof P.R. Life and death of neurons in the aging brain. Science 1997, 278:412-419.
    • (1997) Science , vol.278 , pp. 412-419
    • Morrison, J.H.1    Hof, P.R.2
  • 44
    • 0022517708 scopus 로고
    • Age-dependent increase in the threshold for pentylenetetrazole induced maximal seizure in mice
    • Nokubo M., Kitani K., Ohta M., Kanai S., Sato Y., Masuda Y. Age-dependent increase in the threshold for pentylenetetrazole induced maximal seizure in mice. Life Sci. 1986, 38:1999-2007.
    • (1986) Life Sci. , vol.38 , pp. 1999-2007
    • Nokubo, M.1    Kitani, K.2    Ohta, M.3    Kanai, S.4    Sato, Y.5    Masuda, Y.6
  • 47
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 49
    • 49149105430 scopus 로고    scopus 로고
    • Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice
    • Porte Y., Buhot M.C., Mons N. Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice. Neurobiol. Aging 2008, 29:1533-1546.
    • (2008) Neurobiol. Aging , vol.29 , pp. 1533-1546
    • Porte, Y.1    Buhot, M.C.2    Mons, N.3
  • 50
    • 0027535364 scopus 로고
    • Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
    • Qian Z., Gilbert M.E., Colicos M.A., Kandel E.R., Kuhl D. Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 1993, 361:453-457.
    • (1993) Nature , vol.361 , pp. 453-457
    • Qian, Z.1    Gilbert, M.E.2    Colicos, M.A.3    Kandel, E.R.4    Kuhl, D.5
  • 51
    • 0032985630 scopus 로고    scopus 로고
    • Effect of nitric oxide synthesis inhibition on c-Fos expression in hippocampus and cerebral cortex following two forms of learning in rats: an immunohistochemistry study
    • Qiang M., Xie J., Wang H., Qiao J. Effect of nitric oxide synthesis inhibition on c-Fos expression in hippocampus and cerebral cortex following two forms of learning in rats: an immunohistochemistry study. Behav. Pharmacol. 1999, 10:215-222.
    • (1999) Behav. Pharmacol. , vol.10 , pp. 215-222
    • Qiang, M.1    Xie, J.2    Wang, H.3    Qiao, J.4
  • 52
    • 14044265166 scopus 로고    scopus 로고
    • Spatial exploration-induced Arc mRNA and protein expression: evidence for selective, network-specific reactivation
    • Ramirez-Amaya V., Vazdarjanova A., Mikhael D., Rosi S., Worley P.F., Barnes C.A. Spatial exploration-induced Arc mRNA and protein expression: evidence for selective, network-specific reactivation. J. Neurosci. 2005, 25:1761-1768.
    • (2005) J. Neurosci. , vol.25 , pp. 1761-1768
    • Ramirez-Amaya, V.1    Vazdarjanova, A.2    Mikhael, D.3    Rosi, S.4    Worley, P.F.5    Barnes, C.A.6
  • 53
    • 0029821150 scopus 로고    scopus 로고
    • Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
    • Rapp P.R., Gallagher M. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:9926-9930.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 9926-9930
    • Rapp, P.R.1    Gallagher, M.2
  • 54
    • 0030053883 scopus 로고    scopus 로고
    • Memory impaired aged rats: no loss of principal hippocampal and subicular neurons
    • Rasmussen T., Schliemann T., Sorensen J.C., Zimmer J., West M.J. Memory impaired aged rats: no loss of principal hippocampal and subicular neurons. Neurobiol. Aging 1996, 17:143-147.
    • (1996) Neurobiol. Aging , vol.17 , pp. 143-147
    • Rasmussen, T.1    Schliemann, T.2    Sorensen, J.C.3    Zimmer, J.4    West, M.J.5
  • 55
    • 0030067718 scopus 로고    scopus 로고
    • Seizure induced C-Fos mRNA in the rat brain: comparison between young and aging animals
    • Retchkiman I., Fischer B., Platt D., Wagner A.P. Seizure induced C-Fos mRNA in the rat brain: comparison between young and aging animals. Neurobiol. Aging 1996, 17:41-44.
    • (1996) Neurobiol. Aging , vol.17 , pp. 41-44
    • Retchkiman, I.1    Fischer, B.2    Platt, D.3    Wagner, A.P.4
  • 56
    • 29244487536 scopus 로고    scopus 로고
    • Epilepsy in older adults. Common morbidities influence development, treatment strategies, and expected outcomes
    • Rowan A.J. Epilepsy in older adults. Common morbidities influence development, treatment strategies, and expected outcomes. Geriatrics 2005, 60:30-32.
    • (2005) Geriatrics , vol.60 , pp. 30-32
    • Rowan, A.J.1
  • 57
    • 33947534891 scopus 로고    scopus 로고
    • Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
    • Rowe W.B., Blalock E.M., Chen K.C., Kadish I., Wang D., Barrett J.E., Thibault O., Porter N.M., Rose G.M., Landfield P.W. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J. Neurosci. 2007, 27:3098-3110.
    • (2007) J. Neurosci. , vol.27 , pp. 3098-3110
    • Rowe, W.B.1    Blalock, E.M.2    Chen, K.C.3    Kadish, I.4    Wang, D.5    Barrett, J.E.6    Thibault, O.7    Porter, N.M.8    Rose, G.M.9    Landfield, P.W.10
  • 58
    • 0038413666 scopus 로고    scopus 로고
    • C-Fos expression in supramammillary and medial mammillary nuclei following spatial reference and working memory tasks
    • Santin L.J., Aguirre J.A., Rubio S., Begega A., Miranda R., Arias J.L. c-Fos expression in supramammillary and medial mammillary nuclei following spatial reference and working memory tasks. Physiol. Behav. 2003, 78:733-739.
    • (2003) Physiol. Behav. , vol.78 , pp. 733-739
    • Santin, L.J.1    Aguirre, J.A.2    Rubio, S.3    Begega, A.4    Miranda, R.5    Arias, J.L.6
  • 59
    • 0034993452 scopus 로고    scopus 로고
    • Dynamics of gene expression for immediate early- and late genes after seizure activity in aged rats
    • Schmoll H., Badan I., Fischer B., Wagner A.P. Dynamics of gene expression for immediate early- and late genes after seizure activity in aged rats. Arch. Gerontol. Geriatr. 2001, 32:199-218.
    • (2001) Arch. Gerontol. Geriatr. , vol.32 , pp. 199-218
    • Schmoll, H.1    Badan, I.2    Fischer, B.3    Wagner, A.P.4
  • 61
    • 0029893741 scopus 로고    scopus 로고
    • Age-related decrease in cholinergic synaptic transmission in three hippocampal subfields
    • Shen J., Barnes C.A. Age-related decrease in cholinergic synaptic transmission in three hippocampal subfields. Neurobiol. Aging 1996, 17:439-451.
    • (1996) Neurobiol. Aging , vol.17 , pp. 439-451
    • Shen, J.1    Barnes, C.A.2
  • 63
    • 2342557824 scopus 로고    scopus 로고
    • Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging
    • Small S.A., Chawla M.K., Buonocore M., Rapp P.R., Barnes C.A. Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:7181-7186.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 7181-7186
    • Small, S.A.1    Chawla, M.K.2    Buonocore, M.3    Rapp, P.R.4    Barnes, C.A.5
  • 64
    • 0035174076 scopus 로고    scopus 로고
    • Effect of age and cognitive status on basal level AP-1 activity in rat hippocampus
    • Smith D.R., Hoyt E.C., Gallagher M., Schwabe R.F., Lund P.K. Effect of age and cognitive status on basal level AP-1 activity in rat hippocampus. Neurobiol. Aging 2001, 22:773-786.
    • (2001) Neurobiol. Aging , vol.22 , pp. 773-786
    • Smith, D.R.1    Hoyt, E.C.2    Gallagher, M.3    Schwabe, R.F.4    Lund, P.K.5
  • 65
    • 34548822478 scopus 로고    scopus 로고
    • Effects of aging, dietary restriction and glucocorticoid treatment on housekeeping gene expression in rat cortex and hippocampus-evaluation by real time RT-PCR
    • Tanic N., Perovic M., Mladenovic A., Ruzdijic S., Kanazir S. Effects of aging, dietary restriction and glucocorticoid treatment on housekeeping gene expression in rat cortex and hippocampus-evaluation by real time RT-PCR. J. Mol. Neurosci. 2007, 32:38-46.
    • (2007) J. Mol. Neurosci. , vol.32 , pp. 38-46
    • Tanic, N.1    Perovic, M.2    Mladenovic, A.3    Ruzdijic, S.4    Kanazir, S.5
  • 66
    • 23744439526 scopus 로고    scopus 로고
    • Differential induction of c-Jun and Fos-like proteins in rat hippocampus and dorsal striatum after training in two water maze tasks
    • Teather L.A., Packard M.G., Smith D.E., Ellis-Behnke R.G., Bazan N.G. Differential induction of c-Jun and Fos-like proteins in rat hippocampus and dorsal striatum after training in two water maze tasks. Neurobiol. Learn. Mem. 2005, 84:75-84.
    • (2005) Neurobiol. Learn. Mem. , vol.84 , pp. 75-84
    • Teather, L.A.1    Packard, M.G.2    Smith, D.E.3    Ellis-Behnke, R.G.4    Bazan, N.G.5
  • 67
    • 0032951111 scopus 로고    scopus 로고
    • Activation of immediate early genes and memory formation
    • Tischmeyer W., Grimm R. Activation of immediate early genes and memory formation. Cell. Mol. Life Sci. 1999, 55:564-574.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 564-574
    • Tischmeyer, W.1    Grimm, R.2
  • 68
    • 0037327648 scopus 로고    scopus 로고
    • Fos imaging reveals ageing-related changes in hippocampal response to radial maze discrimination testing in mice
    • Touzani K., Marighetto A., Jaffard R. Fos imaging reveals ageing-related changes in hippocampal response to radial maze discrimination testing in mice. Eur. J. Neurosci. 2003, 17:628-640.
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 628-640
    • Touzani, K.1    Marighetto, A.2    Jaffard, R.3
  • 69
    • 0036896810 scopus 로고    scopus 로고
    • Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks
    • Vazdarjanova A., McNaughton B.L., Barnes C.A., Worley P.F., Guzowski J.F. Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks. J. Neurosci. 2002, 22:10067-10071.
    • (2002) J. Neurosci. , vol.22 , pp. 10067-10071
    • Vazdarjanova, A.1    McNaughton, B.L.2    Barnes, C.A.3    Worley, P.F.4    Guzowski, J.F.5
  • 70
    • 2542637241 scopus 로고    scopus 로고
    • Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice
    • Verbitsky M., Yonan A.L., Malleret G., Kandel E.R., Gilliam T.C., Pavlidis P. Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice. Learn. Mem. 2004, 11:253-260.
    • (2004) Learn. Mem. , vol.11 , pp. 253-260
    • Verbitsky, M.1    Yonan, A.L.2    Malleret, G.3    Kandel, E.R.4    Gilliam, T.C.5    Pavlidis, P.6
  • 71
    • 0033647047 scopus 로고    scopus 로고
    • Brain plasticity: to what extent do aged animals retain the capacity to coordinate gene activity in response to acute challenges
    • Wagner A.P., Schmoll H., Badan I., Platt D., Kessler C. Brain plasticity: to what extent do aged animals retain the capacity to coordinate gene activity in response to acute challenges. Exp. Gerontol. 2000, 35:1211-1227.
    • (2000) Exp. Gerontol. , vol.35 , pp. 1211-1227
    • Wagner, A.P.1    Schmoll, H.2    Badan, I.3    Platt, D.4    Kessler, C.5
  • 72
    • 0034575607 scopus 로고    scopus 로고
    • Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat
    • Wenk G.L., Barnes C.A. Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat. Brain Res. 2000, 885:1-5.
    • (2000) Brain Res. , vol.885 , pp. 1-5
    • Wenk, G.L.1    Barnes, C.A.2
  • 73
    • 0027443739 scopus 로고
    • Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement
    • Worley P.F., Bhat R.V., Baraban J.M., Erickson C.A., McNaughton B.L., Barnes C.A. Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement. J. Neurosci. 1993, 13:4776-4786.
    • (1993) J. Neurosci. , vol.13 , pp. 4776-4786
    • Worley, P.F.1    Bhat, R.V.2    Baraban, J.M.3    Erickson, C.A.4    McNaughton, B.L.5    Barnes, C.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.