Effect of aging on the basal expression of c-Fos, c-Jun, and Egr-1 proteins in the hippocampus

Neurobiology of Aging

Volumn 18, Issue 1, 1997, Pages 37-44

  Desjardins, S ^b   Mayo, W ^b   Vallee M ^b   Hancock, D ^b   Le Moal, M ^b   Simon, H ^b   Abrous, D N ^a  

^a INSERM   (France)

^b NONE

Author keywords

aging; hippocampus; immediate early gene; memory

Indexed keywords

PROTEIN C FOS;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMEDIATE EARLY GENE; MEMORY; NEUROBIOLOGY; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; ASTROCYTES; CELL COUNT; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; IMMEDIATE-EARLY PROTEINS; IMMUNOHISTOCHEMISTRY; MALE; MAZE LEARNING; NERVE DEGENERATION; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTORS;

EID: 0031046743     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(96)00206-0     Document Type: Article

References (57)

1. Abraham, W. C.; Mason, S. E.; Demmer, J.; Williams, J. M.; Richardson, L. C.; Tate, W. P.; Lawlor, P. A.; Dragunow, M. Correlations between immediate early gene induction and the persistence of long-term potentiation. Neuroscience 56:717-727; 1993.
2. Abrous, D. N.; Torres, E. M.; Annett, L. E.; Reading, P.; Dunnett, S. B. Intrastriatal dopaminergic-rich grafts induce a hyperexpression of Fos protein when challenged with amphetamine. Exp. Brain Res. 91:181-190; 1992.
3. Anderson, A. J.; Gumming, B. J.; Cotman, C. W. Increased immuno-reactivity for Jun-and Fos-related proteins in Alzheimer's disease: Association with pathology. Exp. Neurol. 125:286-295; 1994.
4. Anderson, A. J.; Su, J. H.; Cotman, C. W. DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of post-mortem delay. J. Neurosci. 16:1710-1719; 1996.
5. Ball, M. J. Hippocampal histopathology - A critical substrate for dementia of the Alzheimer Type. Interdiscipl. Topics Gerontol. 25:16-37; 1988.
6. Barnes, C. A. Memory deficits associated with senescence: A neurophysiological and behavioural study in the rat. Psychol. J. Comp. Physiol. 93:74-104; 1979.
7. Barnes, C. A. Aging in the physiology of spatial memory. Neurobiol. Aging 9:563-568; 1988.
8. Barnes, C. A.; McNaughton, B. L. An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses. Behav. Neurosci. 99: 1040-1048; 1985.
9. Berman, R. F.; Goldman, H.; Altman, H. J. Age-related changes in regional cerebral flow and behaviour in Sprague-Dawley rats. Neurobiol. Aging 9:691-696; 1988.
10. Bjorklund, H.; Eriksdotter-Nilsson, M.; Dahl, D.; Rose, G.; Hoffer, B.; Olson, L. Image analysis of GFA-positive astrocytes from adolescence to senescence. Exp. Brain Res. 58:163-170; 1985.
11. Brennan, P. A.; Hancock, D.; Keverne, E. B. The expression of the immediate-early genes c-fos, erg-1 and c-jun in the accessory olfactory bulb during the formation of an olfactory memory in mice. Neuroscience 49:2277-2284; 1992.
12. Brizze, K. R.; Ordy, J. M. Age pigments, cell loss and hippocampal function. Mech. Aging Dev. 9:143-162; 1979.
13. Cole, A. J.; Saffen, D. W.; Baraban, J.; Worley, P. F. Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation. Nature 340:474-476; 1989.
14. Diamond, M. C.; Johnson, R. E.; Gold, M. W. Changes in neuron number and size and glia number in the young, adult and aging rat medial occipital cortex. Behav. Biol. 20:409-418; 1977.
15. Fedoroff, S.; Vernedakis, A., eds. Astrocytes: Physiology and pharmacology of astrocytes. Vol 2. New York: Academic Press; 1986.
16. Finch, C. E.; Morgan, D. G. RNA and protein metabolism in the aging brain. Annu. Rev. Neurosci. 13:75-87; 1990.
17. Flood, D. G.; Coleman, P.D. Neuron numbers and sizes in aging brain: Comparisons of human, monkey, and rodent data. Neurobiol. Aging 9:453-463; 1988.
18. Gage, F. H.; Chan, K. S.; Buzsaki, G.; Armstrong, D. Experimental approaches to age-related cognitive impairments. Neurobiol. Aging 9:645-655; 1988.
19. Gallagher, M.; Nicolle, M. M. Animals models of normal aging: Relationship between cognitive decline and markers in hippocampal circuitry. Behav. Brain. Res. 57:155-162; 1993.
20. Gallagher, M.; Burwell, R. D.; Kodsi, M. H.; Mckinney, M.; Southerland, S., Vella-Rountree, L.; Lewis, M. H. Markers for biogenic amines in the aging rat brain: Relationship to decline in spatial learning ability. Neurobiol. Aging 11:507-514; 1990.
21. Gass, P.; Herdegen, T.; Bravo, R.; Kiessling, M. Induction of immediate early gene encoded proteins in rat hippocampus after bicuculline-induced seizures: Differential expression of Krox 24, Fos and Jun proteins. Neuroscience 48:315-324; 1992.
22. Gass, P.; Herdegen, T.; Bravo, R.; Kiessling, M. Induction and suppression of immediate early gene in specific rat brain regions by the non-competitive N-methyl-D-aspartate receptor antagonist MK-801. Neuroscience 53:749-758; 1993.
23. Geinisman, Y.; Bondareff, W.; Dodge, J. T. Hypertrophy of astroglial processes in the dentate gyrus of the senescent rat. Am. J. Anat. 153: 537-543; 1978.
24. Geinisman, Y.; deToledo-Morrell, L.; Morell, F. Loss of perforated synapses in the dentate gyrus: Morphological substrate of memory deficits in aged rats. Proc. Natl. Acad. Sci. USA 83:3027-3031, 1986.
25. Herdegen, T.; Leah, J. D.; Manisali, A.; Bravo, R.; Zimmermann, M. C-jun-like immunoreactivity in the CNS of the adult rat: Basal and transynaptically induced expression of an immediate-early gene. Neuroscience 41:643-654; 1991.
26. Herdegen, T.; Sandkühler, J.; Gass, P.; Bravo, R.; Kiessling, M.; Zimmermann, M. JUN, FOS, KROX and CREB transcription factor proteins in the rat cortex: Basal expression and expression by KCL-induced cortical spreading depression and bicuculline-induced seizures. J. Comp. Neurol. 333:271-288; 1993.
27. Hess, U. S.; Lynch, G.; Gall, C. M. Changes in c-fos mRNA expression in rat brain during odor discrimination learning: Differential involvement of hippocampal subfields CA1 and CA3. J. Neurosci. 15: 4786-4795; 1995.
28. Hughes, P.; Dragunow, M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol. Rev. 47:133-178; 1995.
29. Issa, A. M.; Rowe, W.; Gauthier, S.; Meaney, M. J. Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats. J. Neurosci. 10:3247-3254; 1990.
30. Iwata, K.; Kanda, K.; Tsuboi, Y.; Kitajima, K., Sumino, R. Fos induction in the medullary dorsal horn and C1 segment of the spinal cord by acute inflammation in aged rats. Brain Res. 678:127-139; 1995.
31. Kaminska, B., Kaczmarek, L.; Robust induction of AP-1 transcription factor DNA binding activity in the hippocampus of aged rats. Neurosci. Lett. 153:189-191; 1993.
32. Kitraki, E.; Bozas, E.; Philippidis, H.; Stylianopoulou, F. Aging-related changes in GF-II and c-fos gene expression in the rat brain. Int. J. Dev. Neurosci. 11:1-9; 1993.
33. Kononen, J.; Koistinaho, J.; Alho, H. Circadian rhythm in c-fos-like immunoreactivity in the rat brain. Neurosci. Lett. 120:105-108; 1990.
34. Landfield, P. W.; Baskin, R.; Pitler, T. Brain aging correlates: Retardation by hormonal-pharmacological treatments. Science 214:5881-5884; 1981.
35. Landfield, P. W.; Braun, D. L.; Pitler, T. A.; Lindsey, J. D.; Lynch, G. Hippocampal aging in rats: A morphometric study of multiple variables in semithin sections. Neurobiol. Aging 2:265-275; 1981.
36. Landfield, P. W.; Rose, G.; Sandles, L.; Wohlstader, T. C.; Lynch, G. Patterns of astroglial hypertrophy and neuronal degeneration in the hippocampus of aged, memory-deficient rats. J. Gerontol. 32:3-12; 1977.
37. Landfield, P. W. Hippocampal neurobiological mechanisms of age-related memory dysfunction. Neurobiol. Aging 9:571-579; 1988.
38. Lindsey, J.D.; Landfield, P. W.; Lynch, G. Early onset and topographical distribution of hypertrophied astrocytes in the hippocampus of aging rats: A quantitative study. J. Gerontol. 34:661-671; 1979.
39. Magnoni, M. S.; Govoni, S.; Battanini, F.; Trabucchi, M. Changes in neuronal function downstream from the receptor in the aging brain: Protein kinases and phosphoproteins. Rev. Neurosci. 3:249-470; 1992.
40. Markowska, A. L.; Stone, W. S.; Ingram, D. K.; Reynolds, J.; Gold, P. E.; Conti, L. H.; Pontecorvo, M. J.; Wenk, G. L.; Olton, D. S. Individual differences in aging: Behavioral and neurobiological correlates. Neurobiol. Aging 10:31-43; 1989.
41. McEntee, W. J.; Crook, T. H., Glutamate: Its role in learning, memory and the aging brain. Psychopharmacology (Berlin) 111:391-401; 1993.
42. Morris, R. G. M. Developments of water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods 11:47-60; 1984.
43. Moser, E.; Moser, M. B.; Anderersen, P. Spatial learning impairment parallels the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions. J. Neurosci. 13:3916-3925; 1993.
44. Nikolaev, E.; Kaminska, B.; Tischmeyer, W.; Matthies, H.; Kaczmarek, L. Induction of expression of genes encoding transcription factors in the rat brain elicited by behavioral training. Brain Res. Bull. 28:479-484; 1992.
45. O'Callaghan, J. P.; Miller, D. B. The concentration of glial fibrillary acidic protein increases with age in the mouse and rat brain. Neurobiol. Aging 12:171-174; 1991.
46. Olton, D.S.; Becker, J. T.; Handelmann, G.E. Hippocampus, space and memory. Behav. Brain Sci. 2:313-365; 1979.
47. Paxinos, G. The rat nervous system, 2nd ed. New York: Academic Press; 1995.
48. Pellegrino, L. J.; Pellegrino, A. S.; Cushman, A. J. A stereotaxic atlas of the rat brain. New York: Plenum Press; 1967.
49. Rapp, P. R.; Amaral, D. G. Individual differences in the cognitive and neurobiological consequences of normal aging. Trends Neurosci. 15: 340-345; 1992.
50. Smeyne, R. J.; Vendrell, M.; Hayward, M.; Baker, S. J.; Miao, G. G.; Schilling, K.; Robertson, L. M.; Curran, T.; Morgan, J. I. Continuous c-fos expression precedes programmed cell death in vivo. Nature 363: 166-169; 1993.
51. Sutin, E. L.; Dement, W. C; Heller, H. G.; Kilduff, T. S. Light-induced gene expression in the suprachiasmatic nucleus of young and aging rats. Neurobiol. Aging 14:441-446; 1993.
52. deToledo-Morrell, L.; Geinisman, Y.; Morrell, F. Age-dependent alterations in hippocampal synaptic plasticity: Relation to memory disorders. Neurobiol. Aging 9:581-590; 1988.
53. Vaughan, D. W.; Peters, A. Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: An electron microscope study. J. Neurocytol. 3:405-429; 1979.
54. Wisden, W.; Errington, M. L.; Williams, S.; Dunnett, S. B.; Waters, C.; Hitchcock, D.; Evan, G.; Bliss, T. V. P.; Hunt, S. P. Differential expression of Immediate Early Genes in the hippocampus and spinal cord. Neuron 4:603-614; 1990.
55. Worley, P. F.; Christy, B. A.; Nakabeppu, Y.; Bhat, R.; Cole, A.; Baraban, J. M. Constitutive expression of zif268 in neocortex is regulated by synaptic activity. Proc. Natl. Acad. Sci. USA 88:5106-5110; 1991.
56. Worley, P. F.; Bhat, R.; Baraban, J. M.; Erickson, C. A.; McNaughton, B. L.; Barnes, C. A. Thresholds for synaptic activation of transcription factors in the hippocampus: Correlation with long term enhancement. J. Neurosci. 13:4776-4786; 1993.
57. Zhang, P.; Hirsch, E. C.; Damier, P.; Duyckaerts, C.; Javoy-Agid, F. c-Fos protein-like immunoreactivity: Distribution in the human brain and over-expression in the hippocampus of patients with Alzheimer's disease. Neuroscience 46:9-21; 1992.