Mapping behaviorally relevant neural circuits with immediate-early gene expression

Current Opinion in Neurobiology

Volumn 15, Issue 5, 2005, Pages 599-606

  Guzowski, John F ^a   Timlin, Jerilyn A ^b   Roysam, Badri ^c   McNaughton, Bruce L ^d   Worley, Paul F ^e   Barnes, Carol A ^d  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b SANDIA NATIONAL LABORATORIES   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIOR; BRAIN CORTEX; BRAIN MAPPING; BRAIN REGION; CELL ACTIVITY; ELECTROENCEPHALOGRAM; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE LOCATION; GENETIC ANALYSIS; HUMAN; IMMEDIATE EARLY GENE; IN SITU HYBRIDIZATION; METHODOLOGY; NERVE CELL; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN MAPPING; DIAGNOSTIC IMAGING; GENE EXPRESSION; GENES, IMMEDIATE-EARLY; HUMANS; IN SITU HYBRIDIZATION; NEURAL PATHWAYS;

EID: 25844525608     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2005.08.018     Document Type: Review

References (30)

1. A.J. Cole, D.W. Saffen, J.M. Baraban, and P.F. Worley Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation Nature 340 1989 474 476
2. J.F. Guzowski, B.L. McNaughton, C.A. Barnes, and P.F. Worley Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles Nat Neurosci 2 1999 1120 1124
3. A. Lanahan, and P. Worley Immediate-early genes and synaptic function Neurobiol Learn Mem 70 1998 37 43
4. J.F. Guzowski Insights into immediate-early gene function in hippocampal memory consolidation using antisense oligonucleotide and fluorescent imaging approaches Hippocampus 12 2002 86 104
5. E.C. Tolman Purposive behavior in animals and men 1932 Century
6. W. Link, U. Konietsko, G. Kauselmann, M. Krug, B. Schwanke, U. Frey, and D. Kuhl Somatodendritic expression of an immediate-early gene is regulated by synaptic activity Proc Natl Acad Sci USA 92 1995 5734 5738
7. G.L. Lyford, K. Yamagata, W.E. Kaufmann, C.A. Barnes, L.K. Sanders, N.G. Copeland, D.J. Gilbert, N.A. Jenkins, A.A. Lanahan, and P.F. Worley Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton- associated protein that is enriched in neuronal dendrites Neuron 14 1995 433 445
8. D. Bottai, J.F. Guzowski, M.K. Schwarz, S.H. Kang, B. Xiao, A. Lanahan, P.F. Worley, and P.H. Seeburg Synaptic activity-induced conversion of intronic to exonic sequence in Homer 1 immediate-early gene expression J Neurosci 22 2002 167 175
9. A. Vazdarjanova, B.L. McNaughton, C.A. Barnes, P.F. Worley, and J.F. Guzowski Experience-dependent coincident expression of the effector immediate-early genes Arc and Homer 1a in hippocampal and neocortical neuronal networks J Neurosci 22 2002 10067 10071
10. M.K. Chawla, J.F. Guzowski, V. Ramirez-Amaya, P. Lipa, K.L. Hoffman, L.K. Marriott, P.F. Worley, B.L. McNaughton, and C.A. Barnes Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience Hippocampus 15 2005 579 586
11. A. Vazdarjanova, and J.F. Guzowski Differences in hippocampal neuronal population responses to modifications of an environmental context: evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles J Neurosci 24 2004 6489 6496 This study reported the first use of Arc/H1a catFISH for mapping neural networks activated by two experiences within an animal. The major finding was that CA3 neuronal ensembles had a discontinuous, whereas CA1 ensembles had a graded, population response to minor alterations of an environmental context. These results, predicted from computational models of hippocampal function, suggest that CA3 responds in a nonlinear fashion to changes in input patterns, consistent with the competing functions of pattern separation and pattern completion. The conclusions of this study could not have been reached using conventional IEG methods and comparison of results across animals.
12. M.A. Wilson, and B.L. McNaughton Dynamics of the hippocampal ensemble code for space Science 261 1993 1055 1058
13. C.A. Barnes, B.L. McNaughton, S.J. Mizumori, B.W. Leonard, and L.H. Lin Comparison of spatial and temporal characteristics of neuronal activity in sequential stages of hippocampal processing Prog Brain Res 83 1990 287 300
14. I. Lee, D. Yoganarasimha, G. Rao, and J.J. Knierim Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3 Nature 430 2004 456 459
15. J.F. Guzowski, J.J. Knierim, and E.I. Moser Ensemble dynamics of hippocampal regions CA3 and CA1 Neuron 44 2004 581 584
16. S.N. Burke, M.K. Chawla, M.R. Penner, B.E. Crowell, P.F. Worley, C.A. Barnes, and B.L. McNaughton Differential encoding of behavior and spatial context in deep and superficial layers of the neocortex Neuron 45 2005 667 674 This study provides evidence for what might be an important new principle of neocortical information processing. It shows that the superficial cortical laminae (layers II and III) are sensitive to the spatial and behavioral contexts in which the information represented in the deep layers is received. It is probable that this context sensitivity reflects the highly orthogonal output patterns of the hippocampal formation, which are directed preferentially to these layers.
17. S. Zangenehpour, and A. Chaudhuri Differential induction and decay curves of c-fos and zif268 revealed through dual activity maps Brain Res Mol Brain Res 109 2002 221 225
18. A. Chaudhuri, J. Nissanov, S. Larocque, and L. Rioux Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 mRNA and protein expression Proc Natl Acad Sci USA 94 1997 2671 2675
19. S. Zangenehpour, and A. Chaudhuri Patchy organization and asymmetric distribution of the neural correlates of face processing in monkey inferotemporal cortex Curr Biol 15 2005 993 1005 This study uses detection of both zif268 mRNA and protein, in the same brain sections, to map neural responses to two distinct visual stimuli. The concept of this approach is similar to those described in detail for catFISH here, but relies upon the differential time course of mRNA and protein appearance for the same IEG. The major finding of this study was that neurons responsive to faces versus non-face objects cluster in primate inferotemporal cortex.
20. M.K. Chawla, G. Lin, K. Olson, A. Vazdarjanova, S.N. Burke, B.L. McNaughton, P.F. Worley, J.F. Guzowski, B. Roysam, and C.A. Barnes 3D-catFISH: a system for automated quantitative three-dimensional compartmental analysis of temporal gene transcription activity imaged by fluorescence in situ hybridization J Neurosci Methods 139 2004 13 24 This study describes in detail the software developed for automating cell counts from confocal z-stacks of a catFISH experiment.
21. D.E. Becker, H. Ancin, D.H. Szarowski, J.N. Turner, and B. Roysam Automated 3-D montage synthesis from laser-scanning confocal images: application to quantitative tissue-level cytological analysis Cytometry 25 1996 235 245
22. M.B. Sinclair, J.A. Timlin, D.M. Haaland, and M. Werner-Washburne Design, construction, characterization, and application of a hyperspectral microarray scanner Appl Opt 43 2004 2079 2088 This study describes the design and operation of a hyperspectral microarray scanner. Although originally designed for use on fluorescence based slide microarrays, this scanner design has been modified for use on slide mounted brain tissue stained with multiple fluorescent species. This scanner was used for the data shown in Figure 3.
23. T. Zimmermann, J. Rietdorf, and R. Pepperkok Spectral imaging and its applications in live cell microscopy FEBS Lett 546 2003 87 92
24. R.A. Schultz, T. Nielsen, J.R. Zavaleta, R. Ruch, R. Wyatt, and H.R. Garner Hyperspectral imaging: a novel approach for microscopic analysis Cytometry 43 2001 239 247
25. P.G. Kotula, M.R. Keenan, and J.R. Michael Automated analysis of SEM X-ray spectral images: a powerful new microanalysis tool Microsc Microanal 9 2003 1 17
26. I.L. Medintz, H.T. Uyeda, E.R. Goldman, and H. Mattoussi Quantum dot bioconjugates for imaging, labelling and sensing Nat Mater 4 2005 435 446 Within the past few years, the use of quantum dots for bioimaging studies has expanded dramatically. This review provides an overview of the properties of quantum dots and quantum dot bioconjugates for use in biological studies.
27. A. Matsuno, J. Itoh, S. Takekoshi, T. Nagashima, and R.Y. Osamura Three-dimensional imaging of the intracellular localization of growth hormone and prolactin and their mRNA using nanocrystal (Quantum dot) and confocal laser scanning microscopy techniques J Histochem Cytochem 53 2005 833 838
28. A.L. Barth, R.C. Gerkin, and K.L. Dean Alteration of neuronal firing properties after in vivo experience in a FosGFP transgenic mouse J Neurosci 24 2004 6466 6475
29. W.B. Gan, E. Kwon, G. Feng, J.R. Sanes, and J.W. Lichtman Synaptic dynamism measured over minutes to months: age-dependent decline in an autonomic ganglion Nat Neurosci 6 2003 956 960
30. J.T. Trachtenberg, B.E. Chen, G.W. Knott, G. Feng, J.R. Sanes, E. Welker, and K. Svoboda Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex Nature 420 2002 788 794