CNS distribution of metabotropic glutamate 2 and 3 receptors: Transgenic mice and [3H]LY459477 autoradiography

Neuropharmacology

Volumn 66, Issue , 2013, Pages 89-98

  Wright, Rebecca A ^a   Johnson, Bryan G ^a   Zhang, Ce ^b   Salhoff, Craig ^a   Kingston, Ann E ^a   Calligaro, David O ^a   Monn, James A ^a   Schoepp, Darryle D ^a   Marek, Gerard J ^a  

^a ELI LILLY AND COMPANY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antipsychotic drugs; Autoradiography; LY459477; mGlu2 3 receptor agonists; Mouse mGlu2 receptors; Mouse mGlu3 receptors

Indexed keywords

2 AMINO 4 FLUOROBICYCLO[3.1.0]HEXANE 2,6 DICARBOXYLIC ACID; LY 459477; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR AGONIST; TRACER; TRITIUM 2 AMINO 4 FLUOROBICYCLO[3.1.0]HEXANE 2,6 DICARBOXYLIC ACID H 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING SITE; BRAIN REGION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; EMBRYO; ENTORHINAL CORTEX; FEMALE; GRANULAR CELL; HABENULA; HIPPOCAMPAL CA1 REGION; IN VITRO STUDY; MALE; MAMMILLARY BODY; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PYRIFORM CORTEX; QUANTITATIVE ANALYSIS; SUBSTANTIA NIGRA; THALAMUS RETICULAR NUCLEUS; TRANSGENIC MOUSE;

AMINO ACIDS, DICARBOXYLIC; ANIMALS; BICYCLO COMPOUNDS; BRAIN; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; FEMALE; HUMANS; MALE; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; RADIOLIGAND ASSAY; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; TRITIUM;

EID: 84872156125     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.01.019     Document Type: Article

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