-
1
-
-
84860751699
-
Telomeres and mitochondria in the aging heart
-
Moslehi J., Depinho R.A., Sahin E. Telomeres and mitochondria in the aging heart. Circ Res 2012, 110:1226-1237.
-
(2012)
Circ Res
, vol.110
, pp. 1226-1237
-
-
Moslehi, J.1
Depinho, R.A.2
Sahin, E.3
-
2
-
-
50649101095
-
Puzzles, promises and a cure for ageing
-
Vijg J., Campisi J. Puzzles, promises and a cure for ageing. Nature 2008, 454:1065-1071.
-
(2008)
Nature
, vol.454
, pp. 1065-1071
-
-
Vijg, J.1
Campisi, J.2
-
3
-
-
13944269223
-
The plasticity of aging: insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 2005, 120:449-460.
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
4
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco M.A., Lee H.W., Hande M.P., Samper E., Lansdorp P.M., DePinho R.A., Greider C.W. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 1997, 91:25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
5
-
-
28944455294
-
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity
-
Hao L.Y., Armanios M., Strong M.A., Karim B., Feldser D.M., Huso D., Greider C.W. Short telomeres, even in the presence of telomerase, limit tissue renewal capacity. Cell 2005, 123:1121-1131.
-
(2005)
Cell
, vol.123
, pp. 1121-1131
-
-
Hao, L.Y.1
Armanios, M.2
Strong, M.A.3
Karim, B.4
Feldser, D.M.5
Huso, D.6
Greider, C.W.7
-
6
-
-
71149086939
-
Short telomeres are sufficient to cause the degenerative defects associated with aging
-
Armanios M., Alder J.K., Parry E.M., Karim B., Strong M.A., Greider C.W. Short telomeres are sufficient to cause the degenerative defects associated with aging. Am J Hum Genet 2009, 85:823-832.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 823-832
-
-
Armanios, M.1
Alder, J.K.2
Parry, E.M.3
Karim, B.4
Strong, M.A.5
Greider, C.W.6
-
7
-
-
34447543913
-
Cellular senescence in cancer and aging
-
Collado M., Blasco M.A., Serrano M. Cellular senescence in cancer and aging. Cell 2007, 130:223-233.
-
(2007)
Cell
, vol.130
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
8
-
-
84865396814
-
Assessing cell and organ senescence biomarkers
-
de Jesus B.B., Blasco M.A. Assessing cell and organ senescence biomarkers. Circ Res 2012, 111:97-109.
-
(2012)
Circ Res
, vol.111
, pp. 97-109
-
-
de Jesus, B.B.1
Blasco, M.A.2
-
9
-
-
0034626769
-
The age of cancer
-
DePinho R.A. The age of cancer. Nature 2000, 408:248-254.
-
(2000)
Nature
, vol.408
, pp. 248-254
-
-
DePinho, R.A.1
-
10
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse
-
Greenberg R.A., Chin L., Femino A., Lee K.H., Gottlieb G.J., Singer R.H., Greider C.W., DePinho R.A. Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 1999, 97:515-525.
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
DePinho, R.A.8
-
11
-
-
34247581288
-
Short telomeres limit tumor progression in vivo by inducing senescence
-
Feldser D.M., Greider C.W. Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell 2007, 11:461-469.
-
(2007)
Cancer Cell
, vol.11
, pp. 461-469
-
-
Feldser, D.M.1
Greider, C.W.2
-
12
-
-
84861794399
-
Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis
-
Begus-Nahrmann Y., Hartmann D., Kraus J., Eshraghi P., Scheffold A., Grieb M., Rasche V., Schirmacher P., Lee H.W., Kestler H.A., et al. Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis. J Clin Invest 2012, 122:2283-2288.
-
(2012)
J Clin Invest
, vol.122
, pp. 2283-2288
-
-
Begus-Nahrmann, Y.1
Hartmann, D.2
Kraus, J.3
Eshraghi, P.4
Scheffold, A.5
Grieb, M.6
Rasche, V.7
Schirmacher, P.8
Lee, H.W.9
Kestler, H.A.10
-
13
-
-
84862776643
-
Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases
-
Ding Z., Wu C.J., Jaskelioff M., Ivanova E., Kost-Alimova M., Protopopov A., Chu G.C., Wang G., Lu X., Labrot E.S., et al. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell 2012, 148:896-907.
-
(2012)
Cell
, vol.148
, pp. 896-907
-
-
Ding, Z.1
Wu, C.J.2
Jaskelioff, M.3
Ivanova, E.4
Kost-Alimova, M.5
Protopopov, A.6
Chu, G.C.7
Wang, G.8
Lu, X.9
Labrot, E.S.10
-
14
-
-
34447517413
-
Delayed ageing through damage protection by the Arf/p53 pathway
-
Matheu A., Maraver A., Klatt P., Flores I., Garcia-Cao I., Borras C., Flores J.M., Vina J., Blasco M.A., Serrano M. Delayed ageing through damage protection by the Arf/p53 pathway. Nature 2007, 448:375-379.
-
(2007)
Nature
, vol.448
, pp. 375-379
-
-
Matheu, A.1
Maraver, A.2
Klatt, P.3
Flores, I.4
Garcia-Cao, I.5
Borras, C.6
Flores, J.M.7
Vina, J.8
Blasco, M.A.9
Serrano, M.10
-
15
-
-
34548179310
-
Cancer and ageing: convergent and divergent mechanisms
-
Serrano M., Blasco M.A. Cancer and ageing: convergent and divergent mechanisms. Nat Rev Mol Cell Biol 2007, 8:715-722.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 715-722
-
-
Serrano, M.1
Blasco, M.A.2
-
16
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker D.J., Wijshake T., Tchkonia T., LeBrasseur N.K., Childs B.G., van de Sluis B., Kirkland J.L., van Deursen J.M. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011, 479:232-236.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
LeBrasseur, N.K.4
Childs, B.G.5
van de Sluis, B.6
Kirkland, J.L.7
van Deursen, J.M.8
-
17
-
-
78650758398
-
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
-
Herranz D., Munoz-Martin M., Canamero M., Mulero F., Martinez-Pastor B., Fernandez-Capetillo O., Serrano M. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat Commun 2010, 1:1-8.
-
(2010)
Nat Commun
, vol.1
, pp. 1-8
-
-
Herranz, D.1
Munoz-Martin, M.2
Canamero, M.3
Mulero, F.4
Martinez-Pastor, B.5
Fernandez-Capetillo, O.6
Serrano, M.7
-
18
-
-
84858037735
-
Pten positively regulates brown adipose function, energy expenditure, and longevity
-
Ortega-Molina A., Efeyan A., Lopez-Guadamillas E., Munoz-Martin M., Gomez-Lopez G., Canamero M., Mulero F., Pastor J., Martinez S., Romanos E., et al. Pten positively regulates brown adipose function, energy expenditure, and longevity. Cell Metab 2012, 15:382-394.
-
(2012)
Cell Metab
, vol.15
, pp. 382-394
-
-
Ortega-Molina, A.1
Efeyan, A.2
Lopez-Guadamillas, E.3
Munoz-Martin, M.4
Gomez-Lopez, G.5
Canamero, M.6
Mulero, F.7
Pastor, J.8
Martinez, S.9
Romanos, E.10
-
19
-
-
84859215796
-
Systemic elevation of PTEN induces a tumor-suppressive metabolic state
-
Garcia-Cao I., Song M.S., Hobbs R.M., Laurent G., Giorgi C., de Boer V.C., Anastasiou D., Ito K., Sasaki A.T., Rameh L., et al. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell 2012, 149:49-62.
-
(2012)
Cell
, vol.149
, pp. 49-62
-
-
Garcia-Cao, I.1
Song, M.S.2
Hobbs, R.M.3
Laurent, G.4
Giorgi, C.5
de Boer, V.C.6
Anastasiou, D.7
Ito, K.8
Sasaki, A.T.9
Rameh, L.10
-
20
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
Sahin E., Colla S., Liesa M., Moslehi J., Muller F.L., Guo M., Cooper M., Kotton D., Fabian A.J., Walkey C., et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 2011, 470:359-365.
-
(2011)
Nature
, vol.470
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
Moslehi, J.4
Muller, F.L.5
Guo, M.6
Cooper, M.7
Kotton, D.8
Fabian, A.J.9
Walkey, C.10
-
21
-
-
84864823834
-
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
-
de Jesus B.B., Vera E., Schneeberger K., Tejera A.M., Ayuso E., Bosch F., Blasco M.A. Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. EMBO Mol Med 2012, 4:1-14.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 1-14
-
-
de Jesus, B.B.1
Vera, E.2
Schneeberger, K.3
Tejera, A.M.4
Ayuso, E.5
Bosch, F.6
Blasco, M.A.7
-
22
-
-
55449122193
-
Telomerase reverse transcriptase delays aging in cancer-resistant mice
-
Tomas-Loba A., Flores I., Fernandez-Marcos P.J., Cayuela M.L., Maraver A., Tejera A., Borras C., Matheu A., Klatt P., Flores J.M., et al. Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell 2008, 135:609-622.
-
(2008)
Cell
, vol.135
, pp. 609-622
-
-
Tomas-Loba, A.1
Flores, I.2
Fernandez-Marcos, P.J.3
Cayuela, M.L.4
Maraver, A.5
Tejera, A.6
Borras, C.7
Matheu, A.8
Klatt, P.9
Flores, J.M.10
-
23
-
-
0035355340
-
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
-
Gonzalez-Suarez E., Samper E., Ramirez A., Flores J.M., Martin-Caballero J., Jorcano J.L., Blasco M.A. Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J 2001, 20:2619-2630.
-
(2001)
EMBO J
, vol.20
, pp. 2619-2630
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Ramirez, A.3
Flores, J.M.4
Martin-Caballero, J.5
Jorcano, J.L.6
Blasco, M.A.7
-
24
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn E.H. Structure and function of telomeres. Nature 1991, 350:569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
25
-
-
34548667973
-
Telomere length, stem cells and aging
-
Blasco M.A. Telomere length, stem cells and aging. Nat Chem Biol 2007, 3:640-649.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 640-649
-
-
Blasco, M.A.1
-
27
-
-
10344229954
-
Accelerated telomere shortening in response to life stress
-
Epel E.S., Blackburn E.H., Lin J., Dhabhar F.S., Adler N.E., Morrow J.D., Cawthon R.M. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA 2004, 101:17312-17315.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17312-17315
-
-
Epel, E.S.1
Blackburn, E.H.2
Lin, J.3
Dhabhar, F.S.4
Adler, N.E.5
Morrow, J.D.6
Cawthon, R.M.7
-
28
-
-
34248370975
-
High-throughput telomere length quantification by FISH and its application to human population studies
-
Canela A., Vera E., Klatt P., Blasco M.A. High-throughput telomere length quantification by FISH and its application to human population studies. Proc Natl Acad Sci USA 2007, 104:5300-5305.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5300-5305
-
-
Canela, A.1
Vera, E.2
Klatt, P.3
Blasco, M.A.4
-
29
-
-
23844540299
-
Effects of telomerase and telomere length on epidermal stem cell behavior
-
Flores I., Cayuela M.L., Blasco M.A. Effects of telomerase and telomere length on epidermal stem cell behavior. Science 2005, 309:1253-1256.
-
(2005)
Science
, vol.309
, pp. 1253-1256
-
-
Flores, I.1
Cayuela, M.L.2
Blasco, M.A.3
-
30
-
-
0033518188
-
A telomerase component is defective in the human disease dyskeratosis congenita
-
Mitchell J.R., Wood E., Collins K. A telomerase component is defective in the human disease dyskeratosis congenita. Nature 1999, 402:551-555.
-
(1999)
Nature
, vol.402
, pp. 551-555
-
-
Mitchell, J.R.1
Wood, E.2
Collins, K.3
-
31
-
-
0035960043
-
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
-
Vulliamy T., Marrone A., Goldman F., Dearlove A., Bessler M., Mason P.J., Dokal I. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature 2001, 413:432-435.
-
(2001)
Nature
, vol.413
, pp. 432-435
-
-
Vulliamy, T.1
Marrone, A.2
Goldman, F.3
Dearlove, A.4
Bessler, M.5
Mason, P.J.6
Dokal, I.7
-
32
-
-
78650432352
-
Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice
-
Sacco A., Mourkioti F., Tran R., Choi J., Llewellyn M., Kraft P., Shkreli M., Delp S., Pomerantz J.H., Artandi S.E., et al. Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice. Cell 2010, 143:1059-1071.
-
(2010)
Cell
, vol.143
, pp. 1059-1071
-
-
Sacco, A.1
Mourkioti, F.2
Tran, R.3
Choi, J.4
Llewellyn, M.5
Kraft, P.6
Shkreli, M.7
Delp, S.8
Pomerantz, J.H.9
Artandi, S.E.10
-
33
-
-
79957590947
-
Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase
-
Parry E.M., Alder J.K., Qi X., Chen J.J., Armanios M. Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase. Blood 2011, 117:5607-5611.
-
(2011)
Blood
, vol.117
, pp. 5607-5611
-
-
Parry, E.M.1
Alder, J.K.2
Qi, X.3
Chen, J.J.4
Armanios, M.5
-
34
-
-
0038363599
-
Telomeres in cancer and aging: lessons from the mouse
-
Blasco M.A. Telomeres in cancer and aging: lessons from the mouse. Cancer Lett 2003, 194:183-188.
-
(2003)
Cancer Lett
, vol.194
, pp. 183-188
-
-
Blasco, M.A.1
-
35
-
-
69749092744
-
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
-
Martinez P., Thanasoula M., Munoz P., Liao C., Tejera A., McNees C., Flores J.M., Fernandez-Capetillo O., Tarsounas M., Blasco M.A. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes Dev 2009, 23:2060-2075.
-
(2009)
Genes Dev
, vol.23
, pp. 2060-2075
-
-
Martinez, P.1
Thanasoula, M.2
Munoz, P.3
Liao, C.4
Tejera, A.5
McNees, C.6
Flores, J.M.7
Fernandez-Capetillo, O.8
Tarsounas, M.9
Blasco, M.A.10
-
36
-
-
77952898835
-
TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice
-
Tejera A.M., Stagno d'Alcontres M., Thanasoula M., Marion R.M., Martinez P., Liao C., Flores J.M., Tarsounas M., Blasco M.A. TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Dev Cell 2010, 18:775-789.
-
(2010)
Dev Cell
, vol.18
, pp. 775-789
-
-
Tejera, A.M.1
Stagno d'Alcontres, M.2
Thanasoula, M.3
Marion, R.M.4
Martinez, P.5
Liao, C.6
Flores, J.M.7
Tarsounas, M.8
Blasco, M.A.9
-
37
-
-
40349085766
-
The longest telomeres: a general signature of adult stem cell compartments
-
Flores I., Canela A., Vera E., Tejera A., Cotsarelis G., Blasco M.A. The longest telomeres: a general signature of adult stem cell compartments. Genes Dev 2008, 22:654-667.
-
(2008)
Genes Dev
, vol.22
, pp. 654-667
-
-
Flores, I.1
Canela, A.2
Vera, E.3
Tejera, A.4
Cotsarelis, G.5
Blasco, M.A.6
-
38
-
-
84867878909
-
Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of Dyskeratosis congenita
-
Beier F., Foronda M., Martinez P., Blasco M.A. Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of Dyskeratosis congenita. Blood 2012, 10.1182/blood-2012-03-418038.
-
(2012)
Blood
-
-
Beier, F.1
Foronda, M.2
Martinez, P.3
Blasco, M.A.4
-
39
-
-
0042131826
-
Adult stem cells for tissue repair - a new therapeutic concept?
-
Korbling M., Estrov Z. Adult stem cells for tissue repair - a new therapeutic concept?. N Engl J Med 2003, 349:570-582.
-
(2003)
N Engl J Med
, vol.349
, pp. 570-582
-
-
Korbling, M.1
Estrov, Z.2
-
40
-
-
80053978141
-
Isolation and in vitro expansion of human colonic stem cells
-
Jung P., Sato T., Merlos-Suarez A., Barriga F.M., Iglesias M., Rossell D., Auer H., Gallardo M., Blasco M.A., Sancho E., et al. Isolation and in vitro expansion of human colonic stem cells. Nat Med 2011, 17:1225-1227.
-
(2011)
Nat Med
, vol.17
, pp. 1225-1227
-
-
Jung, P.1
Sato, T.2
Merlos-Suarez, A.3
Barriga, F.M.4
Iglesias, M.5
Rossell, D.6
Auer, H.7
Gallardo, M.8
Blasco, M.A.9
Sancho, E.10
-
41
-
-
34249885603
-
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss
-
Ruzankina Y., Pinzon-Guzman C., Asare A., Ong T., Pontano L., Cotsarelis G., Zediak V.P., Velez M., Bhandoola A., Brown E.J. Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell 2007, 1:113-126.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 113-126
-
-
Ruzankina, Y.1
Pinzon-Guzman, C.2
Asare, A.3
Ong, T.4
Pontano, L.5
Cotsarelis, G.6
Zediak, V.P.7
Velez, M.8
Bhandoola, A.9
Brown, E.J.10
-
42
-
-
79958053622
-
Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase
-
Strong M.A., Vidal-Cardenas S.L., Karim B., Yu H., Guo N., Greider C.W. Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase. Mol Cell Biol 2011, 31:2369-2379.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2369-2379
-
-
Strong, M.A.1
Vidal-Cardenas, S.L.2
Karim, B.3
Yu, H.4
Guo, N.5
Greider, C.W.6
-
43
-
-
84857129282
-
Telomere length in early life predicts lifespan
-
Heidinger B.J., Blount J.D., Boner W., Griffiths K., Metcalfe N.B., Monaghan P. Telomere length in early life predicts lifespan. Proc Natl Acad Sci USA 2012, 109:1743-1748.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1743-1748
-
-
Heidinger, B.J.1
Blount, J.D.2
Boner, W.3
Griffiths, K.4
Metcalfe, N.B.5
Monaghan, P.6
-
44
-
-
22944488871
-
Telomeres and human disease: ageing, cancer and beyond
-
Blasco M.A. Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet 2005, 6:611-622.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 611-622
-
-
Blasco, M.A.1
-
45
-
-
16444367180
-
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice
-
Gonzalez-Suarez E., Geserick C., Flores J.M., Blasco M.A. Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice. Oncogene 2005, 24:2256-2270.
-
(2005)
Oncogene
, vol.24
, pp. 2256-2270
-
-
Gonzalez-Suarez, E.1
Geserick, C.2
Flores, J.M.3
Blasco, M.A.4
-
46
-
-
67650065306
-
Telomerase modulates Wnt signalling by association with target gene chromatin
-
Park J.I., Venteicher A.S., Hong J.Y., Choi J., Jun S., Shkreli M., Chang W., Meng Z., Cheung P., Ji H., et al. Telomerase modulates Wnt signalling by association with target gene chromatin. Nature 2009, 460:66-72.
-
(2009)
Nature
, vol.460
, pp. 66-72
-
-
Park, J.I.1
Venteicher, A.S.2
Hong, J.Y.3
Choi, J.4
Jun, S.5
Shkreli, M.6
Chang, W.7
Meng, Z.8
Cheung, P.9
Ji, H.10
-
47
-
-
84862633910
-
Molecular biology. Wnt regulates TERT-putting the horse before the cart
-
Greider C.W. Molecular biology. Wnt regulates TERT-putting the horse before the cart. Science 2012, 336:1519-1520.
-
(2012)
Science
, vol.336
, pp. 1519-1520
-
-
Greider, C.W.1
-
48
-
-
0035878750
-
Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells
-
Sachsinger J., Gonzalez-Suarez E., Samper E., Heicappell R., Muller M., Blasco M.A. Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells. Cancer Res 2001, 61:5580-5586.
-
(2001)
Cancer Res
, vol.61
, pp. 5580-5586
-
-
Sachsinger, J.1
Gonzalez-Suarez, E.2
Samper, E.3
Heicappell, R.4
Muller, M.5
Blasco, M.A.6
-
49
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
Jaskelioff M., Muller F.L., Paik J.H., Thomas E., Jiang S., Adams A.C., Sahin E., Kost-Alimova M., Protopopov A., Cadinanos J., et al. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 2011, 469:102-106.
-
(2011)
Nature
, vol.469
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.H.3
Thomas, E.4
Jiang, S.5
Adams, A.C.6
Sahin, E.7
Kost-Alimova, M.8
Protopopov, A.9
Cadinanos, J.10
-
50
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
Gonzalez-Suarez E., Samper E., Flores J.M., Blasco M.A. Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet 2000, 26:114-117.
-
(2000)
Nat Genet
, vol.26
, pp. 114-117
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
51
-
-
58149192453
-
Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes
-
Fauce S.R., Jamieson B.D., Chin A.C., Mitsuyasu R.T., Parish S.T., Ng H.L., Kitchen C.M., Yang O.O., Harley C.B., Effros R.B. Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes. J Immunol 2008, 181:7400-7406.
-
(2008)
J Immunol
, vol.181
, pp. 7400-7406
-
-
Fauce, S.R.1
Jamieson, B.D.2
Chin, A.C.3
Mitsuyasu, R.T.4
Parish, S.T.5
Ng, H.L.6
Kitchen, C.M.7
Yang, O.O.8
Harley, C.B.9
Effros, R.B.10
-
52
-
-
79960322707
-
The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
-
de Jesus B.B., Schneeberger K., Vera E., Tejera A., Harley C.B., Blasco M.A. The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell 2011, 10:604-621.
-
(2011)
Aging Cell
, vol.10
, pp. 604-621
-
-
de Jesus, B.B.1
Schneeberger, K.2
Vera, E.3
Tejera, A.4
Harley, C.B.5
Blasco, M.A.6
-
53
-
-
78650973371
-
A natural product telomerase activator as part of a health maintenance program
-
Harley C.B., Liu W., Blasco M., Vera E., Andrews W.H., Briggs L.A., Raffaele J.M. A natural product telomerase activator as part of a health maintenance program. Rejuvenation Res 2011, 14:45-56.
-
(2011)
Rejuvenation Res
, vol.14
, pp. 45-56
-
-
Harley, C.B.1
Liu, W.2
Blasco, M.3
Vera, E.4
Andrews, W.H.5
Briggs, L.A.6
Raffaele, J.M.7
-
54
-
-
84859383206
-
Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis
-
Eitan E., Tichon A., Gazit A., Gitler D., Slavin S., Priel E. Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis. EMBO Mol Med 2012, 4:313-329.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 313-329
-
-
Eitan, E.1
Tichon, A.2
Gazit, A.3
Gitler, D.4
Slavin, S.5
Priel, E.6
-
55
-
-
84861461464
-
Axis of ageing: telomeres, p53 and mitochondria
-
Sahin E., Depinho R.A. Axis of ageing: telomeres, p53 and mitochondria. Nat Rev Mol Cell Biol 2012, 13:397-404.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 397-404
-
-
Sahin, E.1
Depinho, R.A.2
-
56
-
-
84868116500
-
The Rate of increase of short telomeres predicts longevity in mammals
-
Vera E., de Jesus B.B., Foronda M., Blasco M.A. The Rate of increase of short telomeres predicts longevity in mammals. Cell Rep 2012, 10.1016/j.celrep.2012.08.023.
-
(2012)
Cell Rep
-
-
Vera, E.1
de Jesus, B.B.2
Foronda, M.3
Blasco, M.A.4
|