Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice

Oncogene

Volumn 24, Issue 13, 2005, Pages 2256-2270

  González Suárez, Eva ^a   Geserick, Christoph ^a   Flores, Juana M ^b   Blasco, María A ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Aging; Cancer; Maximum lifespan; Mouse models; Telomerase

Indexed keywords

TELOMERASE; DNA BINDING PROTEIN; MESSENGER RNA; PRIMER DNA; TERT PROTEIN, HUMAN; TERT PROTEIN, MOUSE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER; CELL STRAIN K5 M TERT; CELL SURVIVAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME MECHANISM; FEMALE; GENE OVEREXPRESSION; INCIDENCE; KIDNEY FUNCTION; LIFESPAN; MALE; MORTALITY; MOUSE; NONHUMAN; PREMATURE AGING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TELOMERE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; DBA MOUSE; ENZYMOLOGY; GENETICS; HUMAN; HYPERPLASIA; HYPERTROPHY; KIDNEY; LONGEVITY; METABOLISM; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SKIN;

AGING; ANIMALS; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; HUMANS; HYPERPLASIA; HYPERTROPHY; KIDNEY; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TELOMERASE;

EID: 16444367180     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208413     Document Type: Article

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