The scanning ion conductance microscope for cellular physiology

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 1, 2013, Pages

  Lab, Max J ^a   Bhargava, Anamika ^a   Wright, Peter T ^a   Gorelik, Julia ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Cardiomyocytes; Cell mechanics; FRET; SICM; Smart patch clamp; Topography

Indexed keywords

ACCURACY; ATOMIC FORCE MICROSCOPE; CELL FUNCTION; CELL MEMBRANE; FEEDBACK SYSTEM; FLUORESCENCE; HEART MUSCLE CELL; ION CONDUCTANCE; ION CURRENT; LABORATORY DEVICE; MICROSCOPE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SCANNING ELECTRON MICROSCOPE; SCANNING ION CONDUCTANCE MICROSCOPE; TOPOGRAPHY;

ANIMALS; BIOSENSING TECHNIQUES; CELL PHYSIOLOGICAL PROCESSES; EQUIPMENT DESIGN; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; IMAGING, THREE-DIMENSIONAL; ION CHANNELS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE POTENTIALS; MICROELECTRODES; MICROSCOPY; NANOTECHNOLOGY; PATCH-CLAMP TECHNIQUES; RECEPTORS, G-PROTEIN-COUPLED; SECOND MESSENGER SYSTEMS;

EID: 84871885639     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00499.2012     Document Type: Review

References (127)

1. Allison DP, Mortensen NP, Sullivan CJ, Doktycz MJ. Atomic force microscopy of biological samples. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2: 618-634, 2010.
2. Azeloglu EU, Costa KD. Atomic force microscopy in mechanobiology: measuring microelastic heterogeneity of living cells. Methods Mol Biol 736: 303-329, 2011.
3. Baro AM, Miranda R, Alaman J, Garcia N, Binnig G, Rohrer H, Gerber C, Carrascosa JL. Determination of surface topography of biological specimens at high resolution by scanning tunnelling microscopy. Nature 315: 253-254, 1985.
4. Baumgarten CM, Browe DM, Ren Z. Swelling- and stretch-activated chloride channels in the heart: regulation and function. In: Mechanosensitivity in Cells and Tissues, edited by Kamkin A and Kiseleva I. Moscow: Academia, 2005.
5. Berridge MJ. Calcium microdomains: organization and function. Cell Calcium 40: 405-412, 2006.
6. Bers DM. Cardiac excitation-contraction coupling. Nature 415: 198-205, 2002.
7. Binnig G, Quate CF, Gerber C. Atomic force microscope. Phys Rev Lett 56: 930-933, 1986.
8. Bruckbauer A, Zhou D, Ying L, Korchev YE, Abell C, Klenerman D. Multicomponent submicron features of biomolecules created by voltage controlled deposition from a nanopipet. J Am Chem Soc 125: 9834-9839, 2003.
9. Bustamante C, Vesenka J, Tang CL, Rees W, Guthold M, Keller R. Circular DNA molecules imaged in air by scanning force microscopy. Biochemistry 31: 22-26, 1992.
10. Calaghan SC, White E. Mechanical modulation of intracellular ion concentrations: mechanisms and electrical consequences. In: Mechanosensitivity in Cells and Tissues, edited by Kamkin A and Kiseleva I. Moscow: Academia, 2005.
11. Calebiro D, Nikolaev VO, Persani L, Lohse MJ. Signaling by internalized G-protein-coupled receptors. Trends Pharmacol Sci 31: 221-228, 2010.
12. Cheuk W, Chan JK. Subcellular localization of immunohistochemical signals: knowledge of the ultrastructural or biologic features of the antigens helps predict the signal localization and proper interpretation of immunostains. Int J Surg Pathol 12: 185-206, 2004.
13. Cho SJ, Wakade A, Pappas GD, Jena BP. New structure involved in transient membrane fusion and exocytosis. Ann NY Acad Sci 971: 254-256, 2002.
14. Colton RJ, Baselt DR, Dufrene YF, Green JB, Lee GU. Scanning probe microscopy. Curr Opin Chem Biol 1: 370-377, 1997.
15. Cong Y, Ludtke SJ. Single particle analysis at high resolution. Methods Enzymol 482: 211-235, 2010.
16. Crowe WE, Ehrenfeld J, Brochiero E, Wills NK. Apical membrane sodium and chloride entry during osmotic swelling of renal (A6) epithelial cells. J Membr Biol 144: 81-91, 1995.
17. Dai J, Sheetz MP. Mechanical properties of neuronal growth cone membranes studied by tether formation with laser optical tweezers. Biophys J 68: 988-996, 1995.
18. de Jonge N, Peckys DB, Kremers GJ, Piston DW. Electron microscopy of whole cells in liquid with nanometer resolution. Proc Natl Acad Sci USA 106: 2159-2164, 2009.
19. Ding S, Gao C, Gu LQ. Capturing single molecules of immunoglobulin and ricin with an aptamer-encoded glass nanopore. Anal Chem 81: 6649-6655, 2009.
20. Domke KF, Pettinger B. Studying surface chemistry beyond the diffraction limit: 10 years of TERS. Chem Phys Chem 11: 1365-1373, 2010.
21. Dufrene YF, Boonaert CJP, van der Mei HC, Busscher HJ, Rouxhet PG. Probing molecular interactions and mechanical properties of microbial cell surfaces by atomic force microscopy. Ultramicroscopy 86: 113-120, 2001.
22. Dulinska I, Targosz M, Strojny W, Lekka M, Czuba P, Balwierz W, Szymonski M. Stiffness of normal and pathological erythrocytes studied by means of atomic force microscopy. J Biochem Biophys Methods 66: 1-11, 2006.
23. Duman M, Pfleger M, Zhu R, Rankl C, Chtcheglova LA, Neundlinger I, Bozna BL, Mayer B, Salio M, Shepherd D, Polzella P, Moertelmaier M, Kada G, Ebner A, Dieudonne M, Schutz GJ, Cerundolo V, Kienberger F, Hinterdorfer P. Improved localization of cellular membrane receptors using combined fluorescence microscopy and simultaneous topography and recognition imaging. Nanotechnology 21: 115504, 2010.
24. Dutta AK, Korchev YE, Shevchuk AI, Hayashi S, Okada Y, Sabirov RZ. Spatial distribution of maxi-anion channel on cardiomyocytes detected by smart-patch technique. Biophys J 94: 1646-1655, 2008.
25. Errington RJ, Fricker MD, Wood JL, Hall AC, White NS. Fourdimensional imaging of living chondrocytes in cartilage using confocal microscopy: a pragmatic approach. Am J Physiol Cell Physiol 272: C1040-C1051, 1997.
26. Farinas J, Kneen M, Moore M, Verkman AS. Plasma membrane water permeability of cultured cells and epithelia measured by light microscopy with spatial filtering. J Gen Physiol 110: 283-296, 1997.
27. Francis LW, Lewis PD, Wright CJ, Conlan RS. Atomic force microscopy comes of age. Biol Cell 102: 133-143, 2010.28.
28. Frederix PL, Bosshart PD, Engel A. Atomic force microscopy of biological membranes. Biophys J 96: 329-338, 2009.
29. French AS. Mechanotransduction. Ann Rev Physiol 54: 135-152, 1992.
30. Gorelik J, Ali NN, Sheikh Abdul Kadir SH, Lab M, Stojkovic P, Armstrong L, Sviderskaya EV, Negulyaev YA, Klenerman D, Bennett DC, Lako M, Harding SE, Stojkovic M, Korchev YE. Noninvasive imaging of stem cells by scanning ion conductance microscopy: future perspective. Tissue Eng Part C Meth 14: 311-318, 2008.
31. Gorelik J, Gu Y, Spohr HA, Shevchuk AI, Lab MJ, Harding SE, Edwards CR, Whitaker M, Moss GW, Benton DC, Sanchez D, Darszon A, Vodyanoy I, Klenerman D, Korchev YE. Ion channels in small cells and subcellular structures can be studied with a smart patch-clamp system. Biophys J 83: 3296-3303, 2002.
32. Gorelik J, Shevchuk AI, Frolenkov GI, Diakonov IA, Lab MJ, Kros CJ, Richardson GP, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. Dynamic assembly of surface structures in living cells. Proc Natl Acad Sci USA 100: 5819-5822, 2003.
33. Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, Schwartz MA. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 466: 263-266, 2010.
34. 2+ entry channel with dual mechanosensitivity. Cardiovasc Res 53: 9-11, 2002.
35. Gu Y, Gorelik J, Spohr HA, Shevchuk A, Lab MJ, Harding SE, Vodyanoy I, Klenerman D, Korchev YE. High-resolution scanning patch-clamp: new insights into cell function. FASEB J 16: 748-750, 2002.
36. Guilak F. Volume and surface area measurement of viable chondrocytes in situ using geometric modelling of serial confocal sections. J Microsc 173: 245-256, 1994.
37. Haga H, Sasaki S, Kawabata K, Ito E, Ushiki T, Sambongi T. Elasticity mapping of living fibroblasts by AFM and immunofluorescence observation of the cytoskeleton. Ultramicroscopy 82: 253-258, 2000.
38. Hallows KR, Law FY, Packman CH, Knauf PA. Changes in cytoskeletal actin content, F-actin distribution, and surface morphology during HL-60 cell volume regulation. J Cell Physiol 167: 60-71, 1996.
39. Hamill OP. Twenty odd years of stretch-sensitive channels. Pflügers Arch 453: 333-351, 2006.
40. Hansma PK, Drake B, Marti O, Gould SA, Prater CB. The scanning ion-conductance microscope. Science 243: 641-643, 1989.
41. Hawes C, Martin B. Freeze-fracture deep-etch methods. Methods Cell Biol 49: 33-43, 1995.
42. Haydon PG, Lartius R, Parpura V, Marchese-Ragona SP. Membrane deformation of living glial cells using atomic force microscopy. J Microsc 182: 114-120, 1996.
43. Hisatsune C, Mikoshiba K. Novel compartment implicated in calcium signaling-is it an "induced coupling domain"? Sci STKE 2005: e53, 2005.
44. Hochmuth RM. Micropipette aspiration of living cells. J Biomech 33: 15-22, 2000.
45. Hoffmann EK. Cell swelling and volume regulation. Can J Physiol Pharmacol 70 Suppl: S310-S313, 1992.
46. Horber JK, Miles MJ. Scanning probe evolution in biology. Science 302: 1002-1005, 2003.
47. Hur EM, Kim KT. G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity. Cell Signal 14: 397-405, 2002.
48. Inoue R, Jian Z, Kawarabayashi Y. Mechanosensitive TRP channels in cardiovascular pathophysiology. Pharmacol Ther 123: 371-385, 2009.
49. Isenberg G, Kazanski V, Kondratev D, Gallitelli MF, Kiseleva I, Kamkin A. Differential effects of stretch and compression on membrane currents and [Na+]c in ventricular myocytes. Prog Biophys Mol Biol 82: 43-56, 2003.
50. Jacot JG, Dianis S, Schnall J, Wong JY. A simple microindentation technique for mapping the microscale compliance of soft hydrated materials and tissues. J Biomed Mater Res A 79: 485-494, 2006.
51. Janmey PA, Winer JP, Murray ME, Wen Q. The hard life of soft cells. Cell Motil Cytoskeleton 66: 597-605, 2009.
52. Karoutsos V. Scanning probe microscopy: instrumentation and applications on thin films and magnetic multilayers. J Nanosci Nanotechnol 9: 6783-6798, 2009.
53. Kawahara K, Onodera M, Fukuda Y. A simple method for continuous measurement of cell height during a volume change in a single A6 cell. Jpn J Physiol 44: 411-419, 1994.
54. Khayutin VM, Lukoshkova EV, Rogoza AN, Nikolsky VP. Negative feedbacks in the pathogenesis of primary arterial hypertension: mechanosensitivity of the endothelium. Blood Press 4: 70-76, 1995.
55. Klenerman D, Korchev Y. Potential biomedical applications of the scanned nanopipette. Nanomedicine (Lond) 1: 107-114, 2006.
56. Kohl P, Camelliti P, Burton FL, Smith GL. Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation. J Electrocardiol 38: 45-50, 2005.
57. Korchev YE, Bashford CL, Milovanovic M, Vodyanoy I, Lab MJ. Scanning ion conductance microscopy of living cells. Biophys J 73: 653-658, 1997.
58. Korchev YE, Gorelik J, Lab MJ, Sviderskaya EV, Johnston CL, Coombes CR, Vodyanoy I, Edwards CR. Cell volume measurement using scanning ion conductance microscopy. Biophys J 78: 451-457, 2000.
59. Korchev YE, Milovanovic M, Bashford CL, Bennett DC, Sviderskaya EV, Vodyanoy I, Lab MJ. Specialized scanning ion-conductance microscope for imaging of living cells. J Microsc 188: 17-23, 1997.
60. Korchev YE, Negulyaev YA, Edwards CR, Vodyanoy I, Lab MJ. Functional localization of single active ion channels on the surface of a living cell. Nat Cell Biol 2: 616-619, 2000.
61. Korchev YE, Raval M, Lab MJ, Gorelik J, Edwards CR, Rayment T, Klenerman D. Hybrid scanning ion conductance and scanning near-field optical microscopy for the study of living cells. Biophys J 78: 2675-2679, 2000.
62. Kordylewski L, Karrison T, Page E. P-face particle density of freezefractured vertebrate cardiac plasma membrane. Am J Physiol Heart Circ Physiol 245: H992-H997, 1983.
63. Kurachi Y, Ishii M. Cell signal control of the G protein-gated potassium channel and its subcellular localization. J Physiol 554: 285-294, 2004.
64. Kuznetsova TG, Starodubtseva MN, Yegorenkov NI, Chizhik SA, Zhdanov RI. Atomic force microscopy probing of cell elasticity. Micron 38: 824-833, 2007.
65. Lab M. Scanning ion conductance microscopy for imaging and mechanosensitive activation of selected areas of live cells. Mechanosensitivity of the Heart 3: 6, 2012.
66. Lab MJ. Mechanically mediated crosstalk in heart. In: Mechanosensitivity in Cells and Tissues. Moscow: Academia, 2005.
67. Laforge FO, Carpino J, Rotenberg SA, Mirkin MV. Electrochemical attosyringe. Proc Natl Acad Sci USA 104: 11895-11900, 2007.
68. Lekka M, Fornal M, Pyka-Fosciak G, Lebed K, Wizner B, Grodzicki T, Styczen J. Erythrocyte stiffness probed using atomic force microscope. Biorheology 42: 307-317, 2005.
69. Lesniewska E, Giocondi MC, Vie V, Finot E, Goudonnet JP, Le GC. Atomic force microscopy of renal cells: limits and prospects. Kidney Int Suppl 65: S42-S48, 1998.
70. Liu Y, Feng J, Shi L, Niu R, Sun Q, Liu H, Li J, Guo J, Zhu J, Han D. In situ mechanical analysis of cardiomyocytes at nano scales. Nanoscale 4: 99-102, 2012.
71. Ludwig T, Kirmse R, Poole K, Schwarz US. Probing cellular microenvironments and tissue remodeling by atomic force microscopy. Pflügers Arch 456: 29-49, 2008.
72. Lyon AR, Macleod KT, Zhang Y, Garcia E, Kanda GK, Lab MJ, Korchev YE, Harding SE, Gorelik J. Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart. Proc Natl Acad Sci USA 106: 6854-6859, 2009.
73. Mader A, Gruber K, Castelli R, Hermann BA, Seeberger PH, Radler JO, Leisner M. Discrimination of Escherichia coli strains using glycan cantilever array sensors. Nano Lett 12: 420-423, 2012.
74. Manley S, Gillette JM, Patterson GH, Shroff H, Hess HF, Betzig E, Lippincott-Schwartz J. High-density mapping of single-molecule trajectories with photoactivated localization microscopy. Nat Methods 5: 155-157, 2008.
75. McManus ML, Strange K. Acute volume regulation of brain cells in response to hypertonic challenge. Anesthesiology 78: 1132-1137, 1993.
76. Meyer HW, Richter W. Freeze-fracture studies on lipids and membranes. Micron 32: 615-644, 2001.
77. Miragoli M, Lab MJ, Sikkel M, Lyon AR, Gorelik J. Structural remodeling in cardiomyocytes from infarcted hearts potentiates cellular mechano arrhythmic response to nanoscale sarcolemmal perturbation (Meeting abstract). Circulation 124: 2011.
78. Mitsuoka K. Obtaining high-resolution images of biological macromolecules by using a cryo-electron microscope with a liquid-helium cooled stage. Micron 42: 100-106, 2011.
79. Moe PC, Blount P, Kung C. Functional and structural conservation in the mechanosensitive channel MscL implicates elements crucial for mechanosensation. Mol Microbiol 28: 583-592, 1998.
80. Morris CE. Mechanosensitive ion channels. J Membr Biol 113: 93-107, 1990.
81. Muller DJ, Helenius J, Alsteens D, Dufrene YF. Force probing surfaces of living cells to molecular resolution. Nat Chem Biol 5: 383-390, 2009.
82. Muraki K, Shigekawa M, Imaizumi Y. A new insight into the function of TRPV2 in circulatory organs. In: TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades, edited by Liedtke WB, Heller S. Boca Raton, FL: CRC, 2007, chapt. 28.
83. Myhra S. A review of enabling technologies based on scanning probe microscopy relevant to bioanalysis. Biosens Bioelectron 19: 1345-1354, 2004.
84. Nakahari T, Murakami M, Yoshida H, Miyamoto M, Sohma Y, Imai Y. Decrease in rat submandibular acinar cell volume during ACh stimulation. Am J Physiol Gastrointest Liver Physiol 258: G878-G886, 1990.
85. Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science 327: 1653-1657, 2010.
86. Novak P, Li C, Shevchuk AI, Stepanyan R, Caldwell M, Hughes S, Smart TG, Gorelik J, Ostanin VP, Lab MJ, Moss GW, Frolenkov GI, Klenerman D, Korchev YE. Nanoscale live-cell imaging using hopping probe ion conductance microscopy. Nat Methods 6: 279-281, 2009.
87. Oberleithner H. Nanophysiology: fact or fiction? Pflügers Arch 456: 1-2, 2008.
88. Orchard C, Brette F. t-Tubules and sarcoplasmic reticulum function in cardiac ventricular myocytes. Cardiovasc Res 77: 237-244, 2008.
89. 2+-handling proteins. J Cell Biol 160: 475-479, 2003.
90. Peyton SR, Ghajar CM, Khatiwala CB, Putnam AJ. The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function. Cell Biochem Biophys 47: 300-320, 2007.
91. Piper JD, Clarke RW, Korchev YE, Ying L, Klenerman D. A renewable nanosensor based on a glass nanopipette. J Am Chem Soc 128: 16462-16463, 2006.
92. Poggi MA, Gadsby ED, Bottomley LA, King WP, Oroudjev E, Hansma H. Scanning probe microscopy. Anal Chem 76: 3429-3443, 2004.
93. Potter CM, Schobesberger S, Lundberg MH, Weinberg PD, Mitchell JA, Gorelik J. Shape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: scanning ion conductance microscopy study. PLoS One 7: e31228, 2012.
94. Quist AP, Bergman AA, Reimann CT, Oscarsson SO, Sundqvist BU. Imaging of single antigens, antibodies, and specific immunocomplex formation by scanning force microscopy. Scanning Microsc 9: 395-400, 1995.
95. Ramachandran S, Teran AF, Lal R. Potential role of atomic force microscopy in systems biology. Wiley Interdiscip Rev Syst Biol Med 3: 702-716, 2011.
96. Rheinlaender J, Geisse NA, Proksch R, Schaffer TE. Comparison of scanning ion conductance microscopy with atomic force microscopy for cell imaging. Langmuir 27: 697-704, 2011.
97. Rheinlaender J, Schaffer TE. Image formation, resolution, and height measurement in scanning ion conductance microscopy. J Appl Phys 105: 9, 2009.
98. Rodolfa KT, Bruckbauer A, Zhou D, Korchev YE, Klenerman D. Two-component graded deposition of biomolecules with a double-barreled nanopipette. Angew Chem Int Ed Engl 44: 6854-6859, 2005.
99. Rotsch C, Braet F, Wisse E, Radmacher M. AFM imaging and elasticity measurements on living rat liver macrophages. Cell Biol Int 21: 685-696, 1997.
100. Sanchez D, Johnson N, Li C, Novak P, Rheinlaender J, Zhang Y, Anand U, Anand P, Gorelik J, Frolenkov GI, Benham C, Lab M, Ostanin VP, Schaffer TE, Klenerman D, Korchev YE. Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette. Biophys J 95: 3017-3027, 2008.
101. Schermelleh L, Heintzmann R, Leonhardt H. A guide to superresolution fluorescence microscopy. J Cell Biol 190: 165-175, 2010.
102. Scott JD. A-kinase-anchoring proteins and cytoskeletal signaling events. Biochem Soc Trans 31: 87-89, 2003.
103. Sen S, Subramanian S, Discher DE. Indentation and adhesive probingof a cell membrane with AFM: theoretical model and experiments. Biophys J 89: 3203-3213, 2005.
104. Shevchuk AI, Frolenkov GI, Sanchez D, James PS, Freedman N, Lab MJ, Jones R, Klenerman D, Korchev YE. Imaging proteins in membranes of living cells by high-resolution scanning ion conductance microscopy. Angew Chem Int Ed Engl 45: 2212-2216, 2006.
105. Shevchuk AI, Hobson P, Lab MJ, Klenerman D, Krauzewicz N, Korchev YE. Endocytic pathways: combined scanning ion conductance and surface confocal microscopy study. Pflügers Arch 456: 227-235, 2008.
106. Shevchuk AI, Hobson P, Lab MJ, Klenerman D, Krauzewicz N, Korchev YE. Imaging single virus particles on the surface of cell membranes by high-resolution scanning surface confocal microscopy. Biophys J 94: 4089-4094, 2008.
107. Shevchuk AI, Novak P, Takahashi Y, Clarke R, Miragoli M, Babakinejad B, Gorelik J, Korchev YE, Klenerman D. Realizing the biological and biomedical potential of nanoscale imaging using a pipette probe. Nanomedicine (Lond) 6: 565-575, 2011.
108. Stewart MP, Toyoda Y, Hyman AA, Muller DJ. Force probing cell shape changes to molecular resolution. Trends Biochem Sci 36: 444-450, 2011.
109. Stolz M, Raiteri R, Daniels AU, VanLandingham MR, Baschong W, Aebi U. Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy. Biophys J 86: 3269-3283, 2004.
110. Sun HW, Suo R. [Investigation of enhancing effect for hydride generation- atomic fluorescence of transition metal elements]. Guang Pu Xue Yu Guang Pu Fen Xi 28: 2684-2690, 2008.
111. Svoboda K, Block SM. Biological applications of optical forces. Annu Rev Biophys Biomol Struct 23: 247-285, 1994.
112. Takahashi Y, Shevchuk AI, Novak P, Zhang Y, Ebejer N, Macpherson JV, Unwin PR, Pollard AJ, Roy D, Clifford CA, Shiku H, Matsue T, Klenerman D, Korchev YE. Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces. Angew Chem Int Ed Engl 50: 9638-9642, 2011.
113. te Riet J, Katan AJ, Rankl C, Stahl SW, van Buul AM, Phang IY, Gomez-Casado A, Schon P, Gerritsen JW, Cambi A, Rowan AE, Vancso GJ, Jonkheijm P, Huskens J, Oosterkamp TH, Gaub H, Hinterdorfer P, Figdor CG, Speller S. Interlaboratory round robin on cantilever calibration for AFM force spectroscopy. Ultramicroscopy 111: 1659-1669, 2011.
114. Tosolini G, Villanueva LG, Perez-Murano F, Bausells J. Fast onwafer electrical, mechanical, and electromechanical characterization of piezoresistive cantilever force sensors. Rev Sci Instrum 83: 015002, 2012.
115. Turner YT, Roberts CJ, Davies MC. Scanning probe microscopy in the field of drug delivery. Adv Drug Deliv Rev 59: 1453-1473, 2007.
116. van de Linde S, Loschberger A, Klein T, Heidbreder M, Wolter S, Heilemann M, Sauer M. Direct stochastic optical reconstruction microscopy with standard fluorescent probes. Nat Protoc 6: 991-1009, 2011.
117. Webb HK, Truong VK, Hasan J, Crawford RJ, Ivanova EP. Physicomechanical characterisation of cells using atomic force microscopy- current research and methodologies. J Microbiol Methods 86: 131-139, 2011.
118. White E. Mechanosensitive channels: therapeutic targets in the myocardium? Curr Pharm Des 12: 3645-3663, 2006.
119. Willig KI, Kellner RR, Medda R, Hein B, Jakobs S, Hell SW. Nanoscale resolution in GFP-based microscopy. Nat Methods 3: 721-723, 2006.
120. Wozniak M, Keefer JR, Saunders C, Limbird LE. Differential targeting and retention of G protein-coupled receptors in polarized epithelial cells. J Recept Signal Transduct Res 17: 373-383, 1997.
121. Xu LP, Liu Y, Zhang X. Interfacial self-assembly of amino acids and peptides: scanning tunneling microscopy investigation. Nanoscale 3: 4901-4915, 2011.
122. Ying L, Bruckbauer A, Zhou D, Gorelik J, Shevchuk A, Lab M, Korchev Y, Klenerman D. The scanned nanopipette: a new tool for high resolution bioimaging and controlled deposition of biomolecules. Phys Chem Chem Phys 7: 2859-2866, 2005.
123. You HX, Lau JM, Zhang S, Yu L. Atomic force microscopy imaging of living cells: a preliminary study of the disruptive effect of the cantilever tip on cell morphology. Ultramicroscopy 82: 297-305, 2000.
124. Yu H, Yang T, Chen Y, Xu P, Lee DW, Li X. Chemo-mechanical joint detection with both dynamic and static microcantilevers for interhomologue molecular identification. Anal Chem 84: 6679-6685, 2012.
125. Zhang Y, Gorelik J, Sanchez D, Shevchuk A, Lab M, Vodyanoy I, Klenerman D, Edwards C, Korchev Y. Scanning ion conductance microscopy reveals how a functional renal epithelial monolayer maintains its integrity. Kidney Int 68: 1071-1077, 2005.
126. Zhu J, Sabharwal T, Kalyanasundaram A, Guo L, Wang G. Topographic mapping and compression elasticity analysis of skinned cardiac muscle fibers in vitro with atomic force microscopy and nanoindentation. J Biomech 42: 2143-2150, 2009.
127. Zhu Q, Tekola P, Baak JP, Belien JA. Measurement by confocal laser scanning microscopy of the volume of epidermal nuclei in thick skin sections. Anal Quant Cytol Histol 16: 145-152, 1994.