Protein kinase A activation inhibits oncogenic Sonic hedgehog signalling and suppresses basal cell carcinoma of the skin

Experimental Dermatology

Volumn 21, Issue 11, 2012, Pages 847-852

  Makinodan, Eri ^a   Marneros, Alexander G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Basal cell carcinoma; Forskolin; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; MESSENGER RNA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BASAL CELL CARCINOMA; CANCER GROWTH; CANCER INHIBITION; CANCER MODEL; CANCER RESISTANCE; CARCINOMA CELL; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; GENE MUTATION; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CARCINOMA, BASAL CELL; CELL PROLIFERATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; FEMALE; FORSKOLIN; HEDGEHOG PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MICE; MICE, MUTANT STRAINS; MUTATION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SKIN NEOPLASMS;

EID: 84871852492     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/exd.12016     Document Type: Article

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