-
1
-
-
0037025994
-
Dectin-1 is a major β-glucan receptor on macrophages
-
Brown, G. D., Taylor, P. R., Reid, D. M., Willment, J. A., Williams, D. L., Martinez-Pomares, L., Wong, S. Y., and Gordon, S. (2002) Dectin-1 is a major β-glucan receptor on macrophages. J. Exp. Med. 196, 407-412
-
(2002)
J. Exp. Med.
, vol.196
, pp. 407-412
-
-
Brown, G.D.1
Taylor, P.R.2
Reid, D.M.3
Willment, J.A.4
Williams, D.L.5
Martinez-Pomares, L.6
Wong, S.Y.7
Gordon, S.8
-
2
-
-
0038558248
-
Dectin-1 mediates the biological effects of β-glucans
-
Brown, G. D., Herre, J., Williams, D. L., Willment, J. A., Marshall, A. S., and Gordon, S. (2003) Dectin-1 mediates the biological effects of β-glucans. J. Exp. Med. 197, 1119-1124
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1119-1124
-
-
Brown, G.D.1
Herre, J.2
Williams, D.L.3
Willment, J.A.4
Marshall, A.S.5
Gordon, S.6
-
3
-
-
33845977385
-
Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses
-
Sato, K., Yang, X. L., Yudate, T., Chung, J. S., Wu, J., Luby-Phelps, K., Kimberly, R. P., Underhill, D., Cruz, P. D., Jr., and Ariizumi, K. (2006) Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses. J. Biol. Chem. 281, 38854-38866
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38854-38866
-
-
Sato, K.1
Yang, X.L.2
Yudate, T.3
Chung, J.S.4
Wu, J.5
Luby-Phelps, K.6
Kimberly, R.P.7
Underhill, D.8
Cruz Jr., P.D.9
Ariizumi, K.10
-
4
-
-
77953289487
-
Dectin-2 recognition of α-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans
-
Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S. H., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., and Iwakura, Y. (2010) Dectin-2 recognition of α-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity 32, 681-691
-
(2010)
Immunity
, vol.32
, pp. 681-691
-
-
Saijo, S.1
Ikeda, S.2
Yamabe, K.3
Kakuta, S.4
Ishigame, H.5
Akitsu, A.6
Fujikado, N.7
Kusaka, T.8
Kubo, S.9
Chung, S.H.10
Komatsu, R.11
Miura, N.12
Adachi, Y.13
Ohno, N.14
Shibuya, K.15
Yamamoto, N.16
Kawakami, K.17
Yamasaki, S.18
Saito, T.19
Akira, S.20
Iwakura, Y.21
more..
-
5
-
-
77952887713
-
The SYK tyrosine kinase: A crucial player in diverse biological functions
-
Mócsai, A., Ruland, J., and Tybulewicz, V. L. (2010) The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat. Rev. Immunol. 10, 387-402
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 387-402
-
-
Mócsai, A.1
Ruland, J.2
Tybulewicz, V.L.3
-
6
-
-
79953102822
-
Syk-coupled C-type lectins in immunity
-
Kerrigan, A. M., and Brown, G. D. (2011) Syk-coupled C-type lectins in immunity. Trends Immunol. 32, 151-156
-
(2011)
Trends Immunol.
, vol.32
, pp. 151-156
-
-
Kerrigan, A.M.1
Brown, G.D.2
-
7
-
-
84858142445
-
C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses
-
Kingeter, L. M., and Lin, X. (2012) C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses. Cell Mol. Immunol. 9, 105-112
-
(2012)
Cell Mol. Immunol.
, vol.9
, pp. 105-112
-
-
Kingeter, L.M.1
Lin, X.2
-
8
-
-
33846962860
-
Dectin-1 is required for β-glucan recognition and control of fungal infection
-
Taylor, P. R., Tsoni, S. V., Willment, J. A., Dennehy, K. M., Rosas, M., Findon, H., Haynes, K., Steele, C., Botto, M., Gordon, S., and Brown, G. D. (2007) Dectin-1 is required for β-glucan recognition and control of fungal infection. Nat. Immunol. 8, 31-38
-
(2007)
Nat. Immunol.
, vol.8
, pp. 31-38
-
-
Taylor, P.R.1
Tsoni, S.V.2
Willment, J.A.3
Dennehy, K.M.4
Rosas, M.5
Findon, H.6
Haynes, K.7
Steele, C.8
Botto, M.9
Gordon, S.10
Brown, G.D.11
-
9
-
-
69549108298
-
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection
-
Robinson, M. J., Osorio, F., Rosas, M., Freitas, R. P., Schweighoffer, E., Gross, O., Verbeek, J. S., Ruland, J., Tybulewicz, V., Brown, G. D., Moita, L. F., Taylor, P. R., and Reis e Sousa, C. (2009) Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J. Exp. Med. 206, 2037-2051
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2037-2051
-
-
Robinson, M.J.1
Osorio, F.2
Rosas, M.3
Freitas, R.P.4
Schweighoffer, E.5
Gross, O.6
Verbeek, J.S.7
Ruland, J.8
Tybulewicz, V.9
Brown, G.D.10
Moita, L.F.11
Taylor, P.R.12
Reis E Sousa, C.13
-
10
-
-
47249089542
-
The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans
-
Wells, C. A., Salvage-Jones, J. A., Li, X., Hitchens, K., Butcher, S., Murray, R. Z., Beckhouse, A. G., Lo, Y. L., Manzanero, S., Cobbold, C., Schroder, K., Ma, B., Orr, S., Stewart, L., Lebus, D., Sobieszczuk, P., Hume, D. A., Stow, J., Blanchard, H., and Ashman, R. B. (2008) The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans. J. Immunol. 180, 7404-7413
-
(2008)
J. Immunol.
, vol.180
, pp. 7404-7413
-
-
Wells, C.A.1
Salvage-Jones, J.A.2
Li, X.3
Hitchens, K.4
Butcher, S.5
Murray, R.Z.6
Beckhouse, A.G.7
Lo, Y.L.8
Manzanero, S.9
Cobbold, C.10
Schroder, K.11
Ma, B.12
Orr, S.13
Stewart, L.14
Lebus, D.15
Sobieszczuk, P.16
Hume, D.A.17
Stow, J.18
Blanchard, H.19
Ashman, R.B.20
more..
-
12
-
-
67649969806
-
Requirement of phospholipase C-γ2 (PLCγ2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization
-
Tassi, I., Cella, M., Castro, I., Gilfillan, S., Khan, W. N., and Colonna, M. (2009) Requirement of phospholipase C-γ2 (PLCγ2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization. Eur. J. Immunol. 39, 1369-1378
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 1369-1378
-
-
Tassi, I.1
Cella, M.2
Castro, I.3
Gilfillan, S.4
Khan, W.N.5
Colonna, M.6
-
13
-
-
83755168978
-
Phosholipase Cγ2 (PLCγ2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses
-
Gorjestani, S., Yu, M., Tang, B., Zhang, D., Wang, D., and Lin, X. (2011) Phosholipase Cγ2 (PLCγ2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses. J. Biol. Chem. 286, 43651-43659
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 43651-43659
-
-
Gorjestani, S.1
Yu, M.2
Tang, B.3
Zhang, D.4
Wang, D.5
Lin, X.6
-
14
-
-
33747036397
-
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
-
Gross, O., Gewies, A., Finger, K., Schäfer, M., Sparwasser, T., Peschel, C., Förster, I., and Ruland, J. (2006) Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442, 651-656
-
(2006)
Nature
, vol.442
, pp. 651-656
-
-
Gross, O.1
Gewies, A.2
Finger, K.3
Schäfer, M.4
Sparwasser, T.5
Peschel, C.6
Förster, I.7
Ruland, J.8
-
15
-
-
33846469538
-
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
-
Hsu, Y. M., Zhang, Y., You, Y., Wang, D., Li, H., Duramad, O., Qin, X. F., Dong, C., and Lin, X. (2007) The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat. Immunol. 8, 198-205
-
(2007)
Nat. Immunol.
, vol.8
, pp. 198-205
-
-
Hsu, Y.M.1
Zhang, Y.2
You, Y.3
Wang, D.4
Li, H.5
Duramad, O.6
Qin, X.F.7
Dong, C.8
Lin, X.9
-
16
-
-
77956218105
-
CARD9 mediates dectin-2-induced IκBα kinase ubiquitination leading to activation of NF-κB in response to stimulation by the hyphal form of Candida albicans
-
Bi, L., Gojestani, S., Wu, W., Hsu, Y. M., Zhu, J., Ariizumi, K., and Lin, X. (2010) CARD9 mediates dectin-2-induced IκBα kinase ubiquitination leading to activation of NF-κB in response to stimulation by the hyphal form of Candida albicans. J. Biol. Chem. 285, 25969-25977
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25969-25977
-
-
Bi, L.1
Gojestani, S.2
Wu, W.3
Hsu, Y.M.4
Zhu, J.5
Ariizumi, K.6
Lin, X.7
-
17
-
-
52549125928
-
Mincle is an ITAM-coupled activating receptor that senses damaged cells
-
Yamasaki, S., Ishikawa, E., Sakuma, M., Hara, H., Ogata, K., and Saito, T. (2008) Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat. Immunol. 9, 1179-1188
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1179-1188
-
-
Yamasaki, S.1
Ishikawa, E.2
Sakuma, M.3
Hara, H.4
Ogata, K.5
Saito, T.6
-
18
-
-
84863393017
-
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity
-
Strasser, D., Neumann, K., Bergmann, H., Marakalala, M. J., Guler, R., Rojowska, A., Hopfner, K. P., Brombacher, F., Urlaub, H., Baier, G., Brown, G. D., Leitges, M., and Ruland, J. (2012) Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity. Immunity 36, 32-42
-
(2012)
Immunity
, vol.36
, pp. 32-42
-
-
Strasser, D.1
Neumann, K.2
Bergmann, H.3
Marakalala, M.J.4
Guler, R.5
Rojowska, A.6
Hopfner, K.P.7
Brombacher, F.8
Urlaub, H.9
Baier, G.10
Brown, G.D.11
Leitges, M.12
Ruland, J.13
-
19
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., Xiong, J., Takeuchi, M., Kurama, T., and Goeddel, D. V. (1996) TRAF6 is a signal transducer for interleukin-1. Nature 383, 443-446
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
20
-
-
0141678952
-
TRAF6 is a critical factor for dendritic cell maturation and development
-
Kobayashi, T., Walsh, P. T., Walsh, M. C., Speirs, K. M., Chiffoleau, E., King, C. G., Hancock, W. W., Caamano, J. H., Hunter, C. A., Scott, P., Turka, L. A., and Choi, Y. (2003) TRAF6 is a critical factor for dendritic cell maturation and development. Immunity 19, 353-363
-
(2003)
Immunity
, vol.19
, pp. 353-363
-
-
Kobayashi, T.1
Walsh, P.T.2
Walsh, M.C.3
Speirs, K.M.4
Chiffoleau, E.5
King, C.G.6
Hancock, W.W.7
Caamano, J.H.8
Hunter, C.A.9
Scott, P.10
Turka, L.A.11
Choi, Y.12
-
21
-
-
2342629277
-
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
-
Sun, L., Deng, L., Ea, C. K., Xia, Z. P., and Chen, Z. J. (2004) The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol. Cell 14, 289-301
-
(2004)
Mol. Cell
, vol.14
, pp. 289-301
-
-
Sun, L.1
Deng, L.2
Ea, C.K.3
Xia, Z.P.4
Chen, Z.J.5
-
22
-
-
69549116880
-
The E3 ligase TRAF6 regulates Akt ubiquitination and activation
-
Yang, W. L., Wang, J., Chan, C. H., Lee, S. W., Campos, A. D., Lamothe, B., Hur, L., Grabiner, B. C., Lin, X., Darnay, B. G., and Lin, H. K. (2009) The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science 325, 1134-1138
-
(2009)
Science
, vol.325
, pp. 1134-1138
-
-
Yang, W.L.1
Wang, J.2
Chan, C.H.3
Lee, S.W.4
Campos, A.D.5
Lamothe, B.6
Hur, L.7
Grabiner, B.C.8
Lin, X.9
Darnay, B.G.10
Lin, H.K.11
-
23
-
-
33947506493
-
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of i kappa B kinase activation
-
Lamothe, B., Besse, A., Campos, A. D., Webster, W. K., Wu, H., and Darnay, B. G. (2007) Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. J. Biol. Chem. 282, 4102-4112
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4102-4112
-
-
Lamothe, B.1
Besse, A.2
Campos, A.D.3
Webster, W.K.4
Wu, H.5
Darnay, B.G.6
-
24
-
-
54049133340
-
The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL
-
Lamothe, B., Campos, A. D., Webster, W. K., Gopinathan, A., Hur, L., and Darnay, B. G. (2008) The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL. J. Biol. Chem. 283, 24871-24880
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24871-24880
-
-
Lamothe, B.1
Campos, A.D.2
Webster, W.K.3
Gopinathan, A.4
Hur, L.5
Darnay, B.G.6
-
25
-
-
51349164412
-
The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-κB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association
-
McCully, R. R., and Pomerantz, J. L. (2008) The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-κB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association. Mol. Cell Biol. 28, 5668-5686
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 5668-5686
-
-
McCully, R.R.1
Pomerantz, J.L.2
-
26
-
-
65449139593
-
CARD9 versus CARMA1 in innate and adaptive immunity
-
Hara, H., and Saito, T. (2009) CARD9 versus CARMA1 in innate and adaptive immunity. Trends Immunol. 30, 234-242
-
(2009)
Trends Immunol.
, vol.30
, pp. 234-242
-
-
Hara, H.1
Saito, T.2
-
27
-
-
0036150184
-
Receptor activator of NF-κB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6
-
Mizukami, J., Takaesu, G., Akatsuka, H., Sakurai, H., Ninomiya-Tsuji, J., Matsumoto, K., and Sakurai, N. (2002) Receptor activator of NF-κB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6. Mol. Cell Biol. 22, 992-1000
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 992-1000
-
-
Mizukami, J.1
Takaesu, G.2
Akatsuka, H.3
Sakurai, H.4
Ninomiya-Tsuji, J.5
Matsumoto, K.6
Sakurai, N.7
-
28
-
-
0033634977
-
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
-
Takaesu, G., Kishida, S., Hiyama, A., Yamaguchi, K., Shibuya, H., Irie, K., Ninomiya-Tsuji, J., and Matsumoto, K. (2000) TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol. Cell 5, 649-658
-
(2000)
Mol. Cell
, vol.5
, pp. 649-658
-
-
Takaesu, G.1
Kishida, S.2
Hiyama, A.3
Yamaguchi, K.4
Shibuya, H.5
Irie, K.6
Ninomiya-Tsuji, J.7
Matsumoto, K.8
-
29
-
-
67650744586
-
The role of ubiquitin in NF-κB regulatory pathways
-
Skaug, B., Jiang, X., and Chen, Z. J. (2009) The role of ubiquitin in NF-κB regulatory pathways. Annu. Rev. Biochem. 78, 769-796
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 769-796
-
-
Skaug, B.1
Jiang, X.2
Chen, Z.J.3
-
30
-
-
34248570795
-
Ubiquitin-mediated activation of TAK1 and IKK
-
Adhikari, A., Xu, M., and Chen, Z. J. (2007) Ubiquitin-mediated activation of TAK1 and IKK. Oncogene 26, 3214-3226
-
(2007)
Oncogene
, vol.26
, pp. 3214-3226
-
-
Adhikari, A.1
Xu, M.2
Chen, Z.J.3
-
31
-
-
84856927634
-
Myeloid TAKI [corrected] acts as a negative regulator of the LPS response and mediates resistance to endotoxemia
-
Eftychi, C., Karagianni, N., Alexiou, M., Apostolaki, M., and Kollias, G. (2012) Myeloid TAKI [corrected] acts as a negative regulator of the LPS response and mediates resistance to endotoxemia. PLoS One 7, e31550
-
(2012)
PLoS One
, vol.7
-
-
Eftychi, C.1
Karagianni, N.2
Alexiou, M.3
Apostolaki, M.4
Kollias, G.5
-
32
-
-
0034629146
-
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
-
Kishimoto, K., Matsumoto, K., and Ninomiya-Tsuji, J. (2000) TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop. J. Biol. Chem. 275, 7359-7364
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7359-7364
-
-
Kishimoto, K.1
Matsumoto, K.2
Ninomiya-Tsuji, J.3
-
33
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim, J. H., Xiao, C., Paschal, A. E., Bailey, S. T., Rao, P., Hayden, M. S., Lee, K. Y., Bussey, C., Steckel, M., Tanaka, N., Yamada, G., Akira, S., Matsumoto, K., and Ghosh, S. (2005) TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 19, 2668-2681
-
(2005)
Genes Dev.
, vol.19
, pp. 2668-2681
-
-
Shim, J.H.1
Xiao, C.2
Paschal, A.E.3
Bailey, S.T.4
Rao, P.5
Hayden, M.S.6
Lee, K.Y.7
Bussey, C.8
Steckel, M.9
Tanaka, N.10
Yamada, G.11
Akira, S.12
Matsumoto, K.13
Ghosh, S.14
-
34
-
-
33646713486
-
The TGF β activated kinase TAK1 regulates vascular development in vivo
-
Jadrich, J. L., O'Connor, M. B., and Coucouvanis, E. (2006) The TGF β activated kinase TAK1 regulates vascular development in vivo. Development 133, 1529-1541
-
(2006)
Development
, vol.133
, pp. 1529-1541
-
-
Jadrich, J.L.1
O'Connor, M.B.2
Coucouvanis, E.3
-
35
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen, B. E., Burkhardt, C., Reith, W., Renkawitz, R., and Förster, I. (1999) Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8, 265-277
-
(1999)
Transgenic Res.
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Förster, I.5
-
36
-
-
33751229931
-
A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
-
Xie, M., Zhang, D., Dyck, J. R., Li, Y., Zhang, H., Morishima, M., Mann, D. L., Taffet, G. E., Baldini, A., Khoury, D. S., and Schneider, M. D. (2006) A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc. Natl. Acad. Sci. U.S.A. 103, 17378-17383
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 17378-17383
-
-
Xie, M.1
Zhang, D.2
Dyck, J.R.3
Li, Y.4
Zhang, H.5
Morishima, M.6
Mann, D.L.7
Taffet, G.E.8
Baldini, A.9
Khoury, D.S.10
Schneider, M.D.11
-
37
-
-
0033580466
-
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., and Matsumoto, K. (1999) The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398, 252-256
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
38
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J., and Chen, Z. J. (2001) TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
39
-
-
0035834672
-
IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1- induced activation of NFκB
-
Qian, Y., Commane, M., Ninomiya-Tsuji, J., Matsumoto, K., and Li, X. (2001) IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1- induced activation of NFκB. J. Biol. Chem. 276, 41661-41667
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41661-41667
-
-
Qian, Y.1
Commane, M.2
Ninomiya-Tsuji, J.3
Matsumoto, K.4
Li, X.5
-
40
-
-
0035099717
-
Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway
-
Takaesu, G., Ninomiya-Tsuji, J., Kishida, S., Li, X., Stark, G. R., and Matsumoto, K. (2001) Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Mol. Cell Biol. 21, 2475-2484
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 2475-2484
-
-
Takaesu, G.1
Ninomiya-Tsuji, J.2
Kishida, S.3
Li, X.4
Stark, G.R.5
Matsumoto, K.6
-
41
-
-
0036788753
-
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
-
Jiang, Z., Ninomiya-Tsuji, J., Qian, Y., Matsumoto, K., and Li, X. (2002) Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol. Cell Biol. 22, 7158-7167
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 7158-7167
-
-
Jiang, Z.1
Ninomiya-Tsuji, J.2
Qian, Y.3
Matsumoto, K.4
Li, X.5
-
42
-
-
36348932904
-
IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
-
Keating, S. E., Maloney, G. M., Moran, E. M., and Bowie, A. G. (2007) IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination. J. Biol. Chem. 282, 33435-33443
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 33435-33443
-
-
Keating, S.E.1
Maloney, G.M.2
Moran, E.M.3
Bowie, A.G.4
-
43
-
-
77953714711
-
-
Lin, S. C., Lo, Y. C., and Wu, H. Nature 465, 885-890
-
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.C.1
Lo, Y.C.2
Wu, H.3
-
44
-
-
34247205985
-
Phosphorylation and ubiquitination of the IκB kinase complex by two distinct signaling pathways
-
Shambharkar, P. B., Blonska, M., Pappu, B. P., Li, H., You, Y., Sakurai, H., Darnay, B. G., Hara, H., Penninger, J., and Lin, X. (2007) Phosphorylation and ubiquitination of the IκB kinase complex by two distinct signaling pathways. EMBO J. 26, 1794-1805
-
(2007)
EMBO J.
, vol.26
, pp. 1794-1805
-
-
Shambharkar, P.B.1
Blonska, M.2
Pappu, B.P.3
Li, H.4
You, Y.5
Sakurai, H.6
Darnay, B.G.7
Hara, H.8
Penninger, J.9
Lin, X.10
-
45
-
-
33947521944
-
TAK1-dependent signaling requires functional interaction with TAB2/TAB3
-
Besse, A., Lamothe, B., Campos, A. D., Webster, W. K., Maddineni, U., Lin, S. C., Wu, H., and Darnay, B. G. (2007) TAK1-dependent signaling requires functional interaction with TAB2/TAB3. J. Biol. Chem. 282, 3918-3928
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 3918-3928
-
-
Besse, A.1
Lamothe, B.2
Campos, A.D.3
Webster, W.K.4
Maddineni, U.5
Lin, S.C.6
Wu, H.7
Darnay, B.G.8
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