Phospholipase Cγ2 (PLCγ2) is key component in dectin-2 signaling pathway, mediating anti-fungal innate immune responses

Journal of Biological Chemistry

Volumn 286, Issue 51, 2011, Pages 43651-43659

  Gorjestani, Sara ^a,b   Yu, Mei ^c,d   Tang, Bing ^a   Zhang, Dekai ^e   Wang, Demin ^c   Lin, Xin ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c BLOOD RESEARCH INSTITUTE   (United States)

^d NANJING UNIVERSITY   (China)

^e TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBICANS; ANTI-FUNGAL; B CELL RECEPTOR; B CELLS; C-TYPE LECTINS; CANDIDA ALBICANS; CYTOKINE PRODUCTION; FUNGAL INFECTION; IN-VIVO; INNATE IMMUNE RESPONSE; KEY COMPONENT; PATHOGENIC FUNGI; PATTERN RECOGNITION RECEPTORS; PHOSPHOLIPASE C; REACTIVE OXYGEN SPECIES; REDUCED PRODUCTION; SIGNALING COMPONENTS; SIGNALING PATHWAYS;

CANDIDA; CELL MEMBRANES; IMMUNOLOGY; PATTERN RECOGNITION; PIGMENTS; PLANTS (BOTANY);

SIGNALING;

DECTIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FUNGAL CLEARANCE; FUNGUS HYPHAE; IN VIVO STUDY; INFECTION RESISTANCE; INNATE IMMUNITY; MACROPHAGE; MALE; MOUSE; MYCOSIS; NONHUMAN; PATHOGEN CLEARANCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIFUNGAL AGENTS; BONE MARROW; CANDIDA ALBICANS; IMMUNE SYSTEM; IMMUNITY, INNATE; LECTINS; LECTINS, C-TYPE; MACROPHAGES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; NF-KAPPA B; PHOSPHOLIPASE C GAMMA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 83755168978     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.307389     Document Type: Article

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