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Volumn 26, Issue 7, 2007, Pages 1794-1805

Phosphorylation and ubiquitination of the IκB kinase complex by two distinct signaling pathways

Author keywords

I B kinase; Phosphorylation; Ubiquitination

Indexed keywords

CARMA1 PROTEIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; PROTEIN BCL 10; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BCL10 PROTEIN, MOUSE; CARD11 PROTEIN, MOUSE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; I KAPPA B KINASE; IKBKG PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; LYSINE; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN KINASE C; SIGNAL TRANSDUCING ADAPTOR PROTEIN; UBIQUITIN;

EID: 34247205985     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601622     Document Type: Article
Times cited : (90)

References (42)
  • 1
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin Jr AS (1996) The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14: 649-683
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr, A.S.1
  • 3
    • 1942469524 scopus 로고    scopus 로고
    • MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T-cell receptor-induced NF-kappaB activation
    • Che T, You Y, Wang D, Tanner MJ, Dixit VM, Lin X (2004) MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T-cell receptor-induced NF-kappaB activation. J Biol Chem 279: 15870-15876
    • (2004) J Biol Chem , vol.279 , pp. 15870-15876
    • Che, T.1    You, Y.2    Wang, D.3    Tanner, M.J.4    Dixit, V.M.5    Lin, X.6
  • 4
    • 33645977821 scopus 로고    scopus 로고
    • Ubiquitin, TAK1 and IKK: Is there a connection?
    • Chen ZJ, Bhoj V, Seth RB (2006) Ubiquitin, TAK1 and IKK: is there a connection? Cell Death Differ 13: 687-692
    • (2006) Cell Death Differ , vol.13 , pp. 687-692
    • Chen, Z.J.1    Bhoj, V.2    Seth, R.B.3
  • 7
    • 8644283766 scopus 로고    scopus 로고
    • The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse
    • Hara H, Bakal C, Wada T, Bouchard D, Rottapel R, Saito T, Penninger JM (2004) The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse. J Exp Med 200: 1167-1177
    • (2004) J Exp Med , vol.200 , pp. 1167-1177
    • Hara, H.1    Bakal, C.2    Wada, T.3    Bouchard, D.4    Rottapel, R.5    Saito, T.6    Penninger, J.M.7
  • 9
    • 0034624810 scopus 로고    scopus 로고
    • Somatic mutagenesis studies of NF-kappa B signaling in human T cells: Evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein
    • Harhaj EW, Good L, Xiao G, Uhlik M, Cvijic ME, Rivera-Walsh I, Sun SC (2000) Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein. Oncogene 19: 1448-1456
    • (2000) Oncogene , vol.19 , pp. 1448-1456
    • Harhaj, E.W.1    Good, L.2    Xiao, G.3    Uhlik, M.4    Cvijic, M.E.5    Rivera-Walsh, I.6    Sun, S.C.7
  • 10
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-{kappa}B
    • Hayden MS, Ghosh S (2004) Signaling to NF-{kappa}B. Genes Dev 18: 2195-2224
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 11
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
    • Karin M, Ben-Neriah Y (2000) Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 18: 621-663
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 13
    • 15944410614 scopus 로고    scopus 로고
    • PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation
    • Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S (2005) PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science 308: 114-118
    • (2005) Science , vol.308 , pp. 114-118
    • Lee, K.Y.1    D'Acquisto, F.2    Hayden, M.S.3    Shim, J.H.4    Ghosh, S.5
  • 14
    • 8444225946 scopus 로고    scopus 로고
    • The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling
    • Lin X, Wang D (2004) The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling. Semin Immunol 16: 429-435
    • (2004) Semin Immunol , vol.16 , pp. 429-435
    • Lin, X.1    Wang, D.2
  • 15
    • 33746857795 scopus 로고    scopus 로고
    • Essential role of TAK1 in thymocyte development and activation
    • Liu HH, Xie M, Schneider MD, Chen ZJ (2006) Essential role of TAK1 in thymocyte development and activation. Proc Natl Acad Sci USA 103: 11677-11682
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11677-11682
    • Liu, H.H.1    Xie, M.2    Schneider, M.D.3    Chen, Z.J.4
  • 16
    • 0036724051 scopus 로고    scopus 로고
    • The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation
    • Makris C, Roberts JL, Karin M (2002) The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation. Mol Cell Biol 22: 6573-6581
    • (2002) Mol Cell Biol , vol.22 , pp. 6573-6581
    • Makris, C.1    Roberts, J.L.2    Karin, M.3
  • 18
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A (1998) Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395: 82-86
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 19
    • 0038037580 scopus 로고    scopus 로고
    • Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes
    • Newton K, Dixit VM (2003) Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes. Curr Biol 13: 1247-1251
    • (2003) Curr Biol , vol.13 , pp. 1247-1251
    • Newton, K.1    Dixit, V.M.2
  • 20
    • 0037903145 scopus 로고    scopus 로고
    • A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase
    • Ninomiya-Tsuji J, Kajino T, Ono K, Ohtomo T, Matsumoto M, Shiina M, Mihara M, Tsuchiya M, Matsumoto K (2003) A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase. J Biol Chem 278: 18485-18490
    • (2003) J Biol Chem , vol.278 , pp. 18485-18490
    • Ninomiya-Tsuji, J.1    Kajino, T.2    Ono, K.3    Ohtomo, T.4    Matsumoto, M.5    Shiina, M.6    Mihara, M.7    Tsuchiya, M.8    Matsumoto, K.9
  • 21
    • 0032541657 scopus 로고    scopus 로고
    • IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
    • Rothwarf DM, Zandi E, Natoli G, Karin M (1998) IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 395: 297-300
    • (1998) Nature , vol.395 , pp. 297-300
    • Rothwarf, D.M.1    Zandi, E.2    Natoli, G.3    Karin, M.4
  • 22
    • 0345374583 scopus 로고    scopus 로고
    • Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase
    • Ruefli-Brasse AA, French DM, Dixit VM (2003) Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase. Science 302: 1581-1584
    • (2003) Science , vol.302 , pp. 1581-1584
    • Ruefli-Brasse, A.A.1    French, D.M.2    Dixit, V.M.3
  • 24
    • 0345358541 scopus 로고    scopus 로고
    • Differential requirement for Malt1 in T and B cell antigen receptor signaling
    • Ruland J, Duncan GS, Wakeham A, Mak TW (2003) Differential requirement for Malt1 in T and B cell antigen receptor signaling. Immunity 19: 749-758
    • (2003) Immunity , vol.19 , pp. 749-758
    • Ruland, J.1    Duncan, G.S.2    Wakeham, A.3    Mak, T.W.4
  • 26
    • 33846228444 scopus 로고    scopus 로고
    • Antigen-receptor signaling to nuclear factor kappa B
    • Schulze-Luehrmann J, Ghosh S (2006) Antigen-receptor signaling to nuclear factor kappa B. Immunity 25: 701-715
    • (2006) Immunity , vol.25 , pp. 701-715
    • Schulze-Luehrmann, J.1    Ghosh, S.2
  • 28
    • 27944503997 scopus 로고    scopus 로고
    • PKC{beta} regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1
    • Shinohara H, Yasuda T, Aiba Y, Sanjo H, Hamadate M, Watarai H, Sakurai H, Kurosaki T (2005) PKC{beta} regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1. J Exp Med 202: 1423-1431
    • (2005) J Exp Med , vol.202 , pp. 1423-1431
    • Shinohara, H.1    Yasuda, T.2    Aiba, Y.3    Sanjo, H.4    Hamadate, M.5    Watarai, H.6    Sakurai, H.7    Kurosaki, T.8
  • 30
    • 4544273345 scopus 로고    scopus 로고
    • Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator
    • Stilo R, Liguoro D, Di Jeso B, Formisano S, Consiglio E, Leonardi A, Vito P (2004) Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator. J Biol Chem 279: 34323-34331
    • (2004) J Biol Chem , vol.279 , pp. 34323-34331
    • Stilo, R.1    Liguoro, D.2    Di Jeso, B.3    Formisano, S.4    Consiglio, E.5    Leonardi, A.6    Vito, P.7
  • 31
    • 2342629277 scopus 로고    scopus 로고
    • The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
    • Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ (2004) The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 14: 289-301
    • (2004) Mol Cell , vol.14 , pp. 289-301
    • Sun, L.1    Deng, L.2    Ea, C.K.3    Xia, Z.P.4    Chen, Z.J.5
  • 33
    • 0141621240 scopus 로고    scopus 로고
    • A role for NF-{kappa}B essential modifier/I{kappa}B kinase-{gamma} (NEMO/IKK{gamma}) ubiquitination in the activation of the I{kappa}B kinase complex by tumor necrosis factor-{alpha}
    • Tang ED, Wang C-Y, Xiong Y, Guan K-L (2003) A role for NF-{kappa}B essential modifier/I{kappa}B kinase-{gamma} (NEMO/IKK{gamma}) ubiquitination in the activation of the I{kappa}B kinase complex by tumor necrosis factor-{alpha}. J Biol Chem 278: 37297-37305
    • (2003) J Biol Chem , vol.278 , pp. 37297-37305
    • Tang, E.D.1    Wang, C.-Y.2    Xiong, Y.3    Guan, K.-L.4
  • 34
    • 33746111852 scopus 로고    scopus 로고
    • The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
    • Wan YY, Chi H, Xie M, Schneider MD, Flavell RA (2006) The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. Nat Immunol 7: 851-858
    • (2006) Nat Immunol , vol.7 , pp. 851-858
    • Wan, Y.Y.1    Chi, H.2    Xie, M.3    Schneider, M.D.4    Flavell, R.A.5
  • 36
    • 0346993668 scopus 로고    scopus 로고
    • CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1
    • Wang D, Matsumoto R, You Y, Che T, Lin XY, Gaffen SL, Lin X (2004) CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1. Mol Cell Biol 24: 164-171
    • (2004) Mol Cell Biol , vol.24 , pp. 164-171
    • Wang, D.1    Matsumoto, R.2    You, Y.3    Che, T.4    Lin, X.Y.5    Gaffen, S.L.6    Lin, X.7
  • 39
    • 0032986671 scopus 로고    scopus 로고
    • Membrane compartmentation and the response to antigen
    • Xavier R, Seed B (1999) Membrane compartmentation and the response to antigen. Curr Opin Immunol 11: 265-269
    • (1999) Curr Opin Immunol , vol.11 , pp. 265-269
    • Xavier, R.1    Seed, B.2
  • 40
    • 0041381357 scopus 로고    scopus 로고
    • Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells
    • Xue L, Morris SW, Orihuela C, Tuomanen E, Cui X, Wen R, Wang D (2003) Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells. Nat Immunol 4: 857-865
    • (2003) Nat Immunol , vol.4 , pp. 857-865
    • Xue, L.1    Morris, S.W.2    Orihuela, C.3    Tuomanen, E.4    Cui, X.5    Wen, R.6    Wang, D.7
  • 41


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