Phospholipase Cγ2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells

Journal of Biological Chemistry

Volumn 284, Issue 11, 2009, Pages 7038-7046

  Xu, Shengli ^a   Huo, Jianxin ^a   Lee, Koon Guan ^a   Kurosaki, Tomohiro ^b   Lam, Kong Peng ^a,c  

^a AGENCY FOR SCIENCE   (Singapore)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c NONE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; ANTI-FUNGAL; C-TYPE LECTINS; CELL WALLS; CURDLAN; CYTOKINE PRODUCTION; DECTIN-1; DENDRITIC CELLS; INTERLEUKIN-2; INTRACELLULAR CA; PATTERN RECOGNITION RECEPTORS; PHOSPHOLIPASE C; PRE-TREATMENT; PROINFLAMMATORY CYTOKINE; SIGNAL TRANSDUCTION PATHWAYS; TUMOR NECROSIS FACTORS; TYROSINE KINASE; ZYMOSAN;

AMINO ACIDS; DENDRIMERS; PATTERN RECOGNITION; SIGNAL TRANSDUCTION; SIGNALING; TRANSCRIPTION FACTORS;

CALCIUM;

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM; CURDLAN; CYTOKINE; DECTIN 1; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 23; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PATTERN RECOGNITION RECEPTOR; PHOSPHOLIPASE C GAMMA2; PROTEIN ANTIBODY; PROTEIN BCL 10; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; ZYMOSAN; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; BCL10 PROTEIN, MOUSE; BETA GLUCAN; CARD9 PROTEIN, MOUSE; CASPASE; ESTRANE DERIVATIVE; I KAPPA B KINASE; MALT1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NERVE PROTEIN; PHOSPHODIESTERASE INHIBITOR; PHOSPHOLIPASE C GAMMA; PLCG1 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SIGNAL TRANSDUCTION; ANIMAL; CELL WALL; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; FUNGUS; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SECRETION;

FUNGI;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BETA-GLUCANS; CALCIUM; CALCIUM SIGNALING; CASPASES; CELL WALL; CYTOKINES; DENDRITIC CELLS; ENZYME ACTIVATION; ESTRENES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FUNGI; I-KAPPA B KINASE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C GAMMA; PYRROLIDINONES; ZYMOSAN;

EID: 65449131255     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M806650200     Document Type: Article

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