In vivo approaches to identify mutations and in vitro research to reveal underlying mechanisms of genotoxic thresholds

Genes and Environment

Volumn 34, Issue 4, 2012, Pages 146-152

  Nohmi, Takehiko ^a,b   Yamada, Masami ^a   Masumura, Kenichi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

DNA repair; Genotoxic carcinogens; Non genotoxic carcinogens; Practical thresholds; Translesion DNA synthesis

Indexed keywords

CARCINOGEN; CHEMICAL AGENT;

ANALYTIC METHOD; CANCER RISK; CARCINOGENICITY; CONCENTRATION RESPONSE; DEFENSE MECHANISM; DNA DAMAGE; DNA REPAIR; DNA SYNTHESIS; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR INTERACTION; MUTAGENICITY; MUTATIONAL ANALYSIS; NONHUMAN; REVIEW; RISK ASSESSMENT; TOXICITY TESTING; TRANSLESION DNA SYNTHESIS;

RODENTIA;

EID: 84871755117     PISSN: 18807046     EISSN: 18807062     Source Type: Journal    
DOI: 10.3123/jemsge.34.146     Document Type: Review

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