Evaluation of the in vivo mutagenicity of nickel subsulfide in the lung of F344 gpt delta transgenic rats exposed by intratracheal instillation: A Collaborative study for the gpt delta transgenic rat mutation assay

Genes and Environment

Volumn 34, Issue 1, 2012, Pages 34-44

  Kamigaito, Tomoyuki ^a   Noguchi, Tadashi ^a   Narumi, Kazunori ^b   Takashima, Rie ^b   Hamada, Shuichi ^b   Sanada, Hisakazu ^c   Hasuko, Masayuki ^d   Hayashi, Hiroyuki ^e   Masumura, Kenichi ^d   Nohmi, Takehiko ^d  

^a JAPAN INDUSTRIAL SAFETY AND HEALTH ASSOCIATION   (Japan)

^b LSI MEDIENCE CORPORATION   (Japan)

^c KAKEN PHARMACEUTICAL CO LTD   (Japan)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^e MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

F344 gpt delta transgenic rat; Gpt assay; Nickel subsul fide; Spi assay

Indexed keywords

NICKEL SUBSULFIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DELETION MUTANT; DRUG INSTILLATION; FISCHER 344 RAT; GENE DELETION; GENE FREQUENCY; GENOTOXICITY; GENOTYPING TECHNIQUE; IN VIVO STUDY; MUTAGENICITY; NONHUMAN; PNEUMONIA; RAT; TRANSGENIC RAT;

RATTUS; RODENTIA;

EID: 84860682991     PISSN: 18807046     EISSN: 18807062     Source Type: Journal    
DOI: 10.3123/jemsge.34.34     Document Type: Article

References (67)

1. Kohler SW, Provost GS, Kretz PL, Fieck A, Sorge JA, Short JM. The use of transgenic mice for short-term, in vivo mutagenicity testing. Genet Anal Tech Appl. 1990; 7: 212-8.
2. Dycaico MJ, Provost GS, Kretz PL, Ransom SL, Moores JC, Short JM. The use of shuttle vectors for mutation analysis in transgenic mice and rats. Mutat Res. 1994; 307: 461-78. (Pubitemid 24170560)
3. Gossen JA, de Leeuw WJ, Tan CH, Zwarthoff EC, Berends F, Lohman PH, Knook DL, Vijg J. Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo. Proc Natl Acad Sci USA. 1989; 86: 7971-5. (Pubitemid 19265301)
4. - and 6-thioguanine selections. Environ Mol Mutagen. 1996; 28: 465-70. (Pubitemid 126450192)
5. - selections. Environ Mol Mutagen. 2003; 41: 253-9. (Pubitemid 36529772)
6. Nohmi T, Suzuki T, Masumura K. Recent advances in the protocols of transgenic mouse utation assays. Mutat Res. 2000; 455: 191-215.
7. Masumura K. Spontaneous and induced gpt and Spimutant frequencies in gpt delta transgenic rodents. Genes Environ. 2009; 31: 105-18.
8. Masumura K, Matsui M, Katoh M, Horiya N, Ueda O, Tanabe H, Yamada M, Suzuki H, Sofuni T, Nohmi T. Spectra of gpt mutations in ethylnitrosourea- treated and untreated transgenic mice. Environ Mol Mutagen. 1999; 34: 1-8. (Pubitemid 29420232)
9. Okada N, Masumura K, Nohmi T, Yajima N. E?ient detection of deletions induced by a single treatment of mitomycin C in transgenic mouse gpt delta using the Spi(-) selection. Environ Mol Mutagen. 1999; 34: 106-11. (Pubitemid 29504171)
10. Masumura K, Matsui K, Yamada M, Horiguchi M, Ishida K, Watanabe M, Ueda O, Suzuki H, Kanke Y, Tindall KR, Wakabayashi K, Sofuni T, Nohmi T. Mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in new gpt delta transgenic mouse. Cancer Lett. 1999; 143: 241-4. (Pubitemid 29392964)
11. Nohmi T, Suzuki M, Masumura K, Yamada M, Matsui K, Ueda O, Suzuki H, Katoh M, Ikeda H, Sofuni T. Spi(-) selection: An efficient method to detect gammaray-induced deletions in transgenic mice. Environ Mol Mutagen. 1999; 34: 9-15. (Pubitemid 29420233)
12. Okudaira N, Uehara Y, Fjikawa K, Kagawa N, Ootsuyama A, Norimura T, Saeki K, Nohmi T, Masumura K, Matsumoto T, Oghiso Y, Tanaka K, Ichinohe K, Nakamura S, Tanaka S, Ono T. Radiation dose-rate effect on mutation induction in spleen and liver of gpt delta mice. Radiat Res. 2010; 173: 138-47.
13. Totsuka Y, Higuchi T, Imai T, Nishikawa A, Nohmi T, Kato T, Masuda S, Kinae N, Hiyoshi K, Ogo S, Kawanishi M, Yagi T, Ichinose T, Fukumori N, Watanabe M, Sugimura T. Genotoxicity of nano/microparticles in in vivo micronuclei, in vivo comet and mutation assay system. Part Fibre Toxicol. 2009; 3: 6-23.
14. Heddle JA, Dean S, Nohmi T, Boerrigter M, Casciano D, Douglas GR, Glickman BW, Gorelick NJ, Mirsalis JC, Martus H, Skopek TR, Thybaud V, Tindall KR, Yajima N. In vivo transgenic mutation assays. Environ Mol Mutagen. 2000; 35: 253-9. (Pubitemid 30196668)
15. Thybaud V, Dean S, Nohmi T, deBoer J, Douglas GR, Glickman BW, Gorelick NJ, Heddle JA, Heflich RH, Lambert I, Martis HJ, Mirsalis JC, Suzuki T, Yajima N. In vivo transgenic mutation assays. Mutat Res. 2003; 540: 141-51. (Pubitemid 37204938)
16. Lambert IB, Singer TM, Boucher SE, Douglas GR. Detailed review of transgenic rodent mutation assays. Mutat Res. 2005; 590: 1-280. (Pubitemid 41121981)
17. OECD, Detailed review paper on transgenic rodent mutation assays. Series on testing and assessment No. 103. OECD Environment, Health and Safety Publications; 2009. Available at: http://www.oecd.org/document/30/0,3746,en- 2649-34377-1916638-1-1-1-1,00.html (accessed 28 September 2011).
18. IARC, IARC Monographs on the evaluation of the carcinogenic risk of chemicals to man: Cadmium, nickel, some epoxides, miscellaneous industrial chemicals and general considerations on volatile anesthetics. Vol. 11. Lyon: IARC Scientific Publications; 1976. p. 75-112.
19. IARC, IARC Monographs on the evaluation of the carcinogenic risks to human. Chromium, nickel and welding. Vol. 49. Lyon: IARC Scientific Publications; 1990.
20. 1 mice (inhalation studies). Natl Toxicol Program Tech Rep Ser. 1996; 453: 5-122.
21. Sunderman FW Jr, Maenza RM. Comparisons of carcinogenicities of nickel compounds in rats. Res Commun Chem Pathol Pharmacol. 1976; 14: 319-30.
22. Yamashiro S, Gilman JPW, Hulland TJ, Abandowitz HM. Nickel sulphide-induced rhabdomyosarcoma in rats. Acta Pathol Jpn. 1980; 30: 9-22.
23. Jasmin G, Riopelle JL. Renal carcinomas and erythrocytosis in rats following intrarenal injection of nickel subsulfide. Lab Invest. 1976; 35: 71-8.
24. Sunderman FW Jr, Maenza RM, Hopfer SM, Michell JM, Allpass PR, Damjanov I. Induction of renal cancers in rats by intrarenal injection of nickel subsulfide. J Environ Pathol Toxicol. 1979; 21: 1511-27. (Pubitemid 10145679)
25. Damjanov I, Sunderman FW Jr, Michell JM, Allpass PR. Induction of testicular sarcomas in Fischer rats by intratesticular injection of nickel subsulfide. Cancer Res. 1978; 38: 268-76. (Pubitemid 8283945)
26. Albert DM, Gonder JR, Papale J, Craft JL, Dohlman HG, Reid MC, Sunderman FW Jr. Induction of ocular neoplasms in Fischer rats by intraocular injection of nickel subsulfide. Invest Ophthalmol Vis Sci. 1982; 22: 768-82. (Pubitemid 12051305)
27. Kasprzak KS, Sunderman FW Jr, Salnikow K. Nickel carcinogenesis. Mutat Res. 2003; 533: 67-97. (Pubitemid 37487861)
28. Marzin D, Vophi H. Study of mutagenicity of metal derivatives with Salmonella typhimurium TA102. Mutat Res. 1985; 155: 49-51. (Pubitemid 15170967)
29. 2. Mutagenesis. 1990; 6: 583-9. (Pubitemid 20386562)
30. Sunderman FW Jr. Recent research on nickel carcinogenesis. Environ Health Perspect. 1981; 40: 131-41. (Pubitemid 12231153)
31. Biggart NW, Costa M. Assessment of the uptake and mutagenicity of nickel chloride in salmonella tester strains. Mutat Res. 1986; 175: 209-15. (Pubitemid 17172889)
32. Magos L. Epidemiological and experimental aspects of metal carcinogenesis: physicochemical properties, kinetics, and the active species. Environ Health Perspect. 1991; 95: 157-89.
33. Hartwig A. Current aspects in metal genotoxicity. Biometals. 1995; 8: 3-11.
34. Pikalek P, Necasek J. The mutagenic activity of nickel in Corynebacterium sp. Folia Microbiologica. 1983; 28: 17-21.
35. Biedermann KA, Landolph JT. Induction of anchorage independence in human diploid foreskin fibroblasts by carcinogenic metal salts. Cancer Res. 1987; 47: 3815-23. (Pubitemid 17105732)
36. Sen P, Conway K, Costa M. Comparison of the localization of chromosome damage induced by calcium chromate and nickel compounds. Cancer Res. 1987; 47: 2142-7. (Pubitemid 17074623)
37. Conway K, Costa M. Nonrandom chromosomal alterations in nickel-transformed Chinese hamster embryo cells. Cancer Res. 1989; 49: 6032-8. (Pubitemid 19274166)
38. Sen P, Costa M. Incidence and localization of sister chromatid exchanges induced by nickel and chromium compounds. Cancer Res. 1986; 7: 1527-33.
39. Costa M, Salnikow K, Cosentino S, Klein CB, Huang X, Zhuang Z. Molecular mechanisms of nickel carcinogenesis. Environ Health Perspect. 1994; 102 Suppl 3: 127-30. (Pubitemid 24316371)
40. Kawanishi S, Inoue S, Oikawa S, Yamashita N, Toyokuni S, Kawanishi M, Nishino K. Oxidative DNA damage in cultured cells and rat lungs by carcinogenic nickel compounds. Free Radic Biol Med. 2001; 31: 108-16. (Pubitemid 32568430)
41. Mayer C, Klein RG, Wesch H, Schmezer P. Nickel subsulfide is genotoxic in vitro but shows no mutagenic potential in respiratory tract tissues of BigBlue} rats and Muta Mouse in vivo after inhalation. Mutat Res. 1998; 420: 85-98. (Pubitemid 29000966)
42. Toyoda-Hokaiwado N, Inoue T, Masumura K, Hayashi H, Kawamura Y, Kurata Y, Takamune M, Yamada M, Sanada H, Umemura T, Nishikawa A, Nohmi T. Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers. Toxicol Sci. 2010; 114, 71-8.
43. Wolfson MR, Shaffer TH. Pulmonary applications of perfluorochemical liquids: ventilation and beyond. Paediatr Respir Rev. 2005; 6: 117-27. (Pubitemid 40692049)
44. Lewis TR, Morrow PE, MaaClellan RO, Raabe OG, Kennedy GL, Schwetz BA, Goehl TJ, Roycroft JH, Chhabre RS. Establishing aerosol exposure concentrations for inhalation studies. Toxicol Appl Pharmacol. 1989; 99: 377-83. (Pubitemid 19189752)
45. Marrow PE. Possible mechanisms to explain dust overloading of the lungs. Fundum Appl Toxicol. 1988; 10: 369-84.
46. Sui H, Ohta R, Shiragiku T, Akahori A, Suzuki K, Nakajima M, Hayashi H, Masumura K, Nohmi T. Evaluation of in vivo mutagenicity by 2,4-diaminotoluene and 2,6-diaminotoluene in liver of F344 gpt delta transgenic rat dosed for 28 days: a collaborative study of gpt delta transgenic rat mutation assay. Genes Environ. 2012; 34: 25-33.
47. Dunnick JK, Elwell MR, Benson JM, Hobbs CH, Hahn FF, Halt PJ, Cheng YS, Eidson FF. Lung toxicity after 13-week inhalation exposure to nickel oxide, nickel subsulfide, or nickel sulfate hexahydrate in F344/N rats and B6C3F1 mice. Fundam Appl Toxicol. 1989; 12: 584-94. (Pubitemid 19104352)
48. Oberdoärster G. Lung particle overload: implications for occupational exposure to particles. Regul Toxicol Pharmacol. 1995; 21: 123-35.
49. Pulido MD, Parrish AR. Metal-induced apoptosis: Mechanisms. Mutat Res. 2003; 533: 227-41. (Pubitemid 37487871)
50. Bottin MC, Gate L, Rihn B, Micillino JC, Nathalie M, Martin A, Nunge H, Morel G, Worbel R, Ayi-Fanou L, Champmartin C, Keith G, Binet S. Genotoxic effects of bitumen fumes in Big Blue} transgenic rat lung. Mutat Res. 2006; 596: 91-105.
51. Rihn B, Coulais C, Kauffer E, Bottin M-C, Martin P, Yvon F, Vigneron JC, Binet S, Monhoven N, Steiblen G, Keith G. Inhaled crocidolite mutagenicity in lung DNA. Environ Health Perspect. 2000; 108 Suppl 4: 341-6. (Pubitemid 30251838)
52. Micillino JC, Coulais C, Binet S, Bottin M-C, Keith G, Moulin D, Rihn BH. Lack of genotoxicity of bitumen fumes in transgenic mouse lung. Toxicology. 2002; 170: 11-20. (Pubitemid 34031860)
53. Topinka J, Loli P, Georgiadis P, Dusinska M, Hurbankova M, Kovacikova Z, Volkovova K, Kazimirova A, Barancokova M, Tatrai E, Oesterle D, Wolff T, Kyrtopoulos SA. Mutagenesis by asbestos in the lung of llacI transgenic rats. Mutat Res. 2004; 553: 67-78. (Pubitemid 38996797)
54. Donaldson K, Brown GM, Brown DM, Bolton RE, Davis JM. Inflammation generating potential of long and short fibre amosite asbestos samples. Br J Ind Med. 1989; 46: 271-6. (Pubitemid 19107390)
55. Kamp DW, Graceffa P, Pryor WA, Weitzman SA. The role of free radicals in asbestos-induced diseases. Free Radic Biol Med. 1992; 12: 293-315.
56. Kamp DW, Weitzman SA. The molecular basis of asbestos induced lung injury. Thorax. 1999; 54: 638-52. (Pubitemid 29296687)
57. Lee YW, Klein CB, Kargacin B, Salnikow K, Kitahara J, Dowjat K, Zhitkovich A, Christie NT, Costa M. Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens. Mol Cell Biol. 1995; 15: 2527-57.
58. Castranova V, Rabovsky J, Tucker JH, Miles PR. The alveolar type II epitherial cell: A multifunctional pneumocytes. Toxicol Appl Pharmacol. 1988; 93: 472-83.
59. Cairns J. Somatic stem cells and the kinetics of mutagenesis and carcinogenesis. Proc Natl Acad Sci USA. 2002; 99: 10567-70.
60. Sarasin A. An overview of the mechanisms of mutagenesis and carcinogenesis. Mutat Res. 2003; 544: 99-106. (Pubitemid 37487653)
61. Pinkerton KE, Barry BE, O'neil BJ, Raub JA, Pratt PC, Crapo JD. Morphologic changes in the lung during the lifespan of Fischer 344 rats. Am J Anatomy. 1982; 164: 155-74. (Pubitemid 12081634)
62. Jones AL, Spring-Mills E. The liver and gallbladder. In: Histology: cell and tissue biology. 5th ed.Weiss L, editor. New York: Elsevier Science Ltd; 1983. p. 707-48.
63. Cross CE, Vliet A, Louie S, Thiele JJ, Halliwell B. Oxidative stress and antioxidants at biosurfaces: plants, skin, and respiratory tract surfaces. Environ Health Perspect. 1998; 106 Suppl 5: 1241-51. (Pubitemid 28554534)
64. Noda Y, Suzuki T, Kohara A, Hasegawa A, Yotsuyanagi T, Hayashi M, Sofuni T, Yamanaka K, Okada S. In vivo genotoxicity evaluation of dimethylarsinic acid in Muta Mouse. Mutat Res. 2002; 513: 205-12. (Pubitemid 33099998)
65. Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Nohmi T, Yamamoto M. Enhanced spontaneous and Benzo(a) pyrene-induced mutations in the lung of Nrf2-deficinet gpt delta mice. Cance Res. 2007; 67: 5643-8. (Pubitemid 46984995)
66. Hashimoto AH, Amanuma K, Hiyoshi K, Takano H, Masumura K, Nohmi T, Aoki Y. In vivo mutagenesis in the lungs of gpt-delta transgenic mice treated intratracheally with 1,6-dinitropyrene. Environ Mol Mutagen. 2006; 47: 277-83.
67. Hashimoto AH, Amanuma K, Masumura K, Nohmi T, Aoki Y. In vivo mutagenesis caused by diesel exhaust in the tests of gpt delta transgenic mice. Genes Environ. 2009; 31: 1-8.