IL-13 Promotes Collagen Accumulation in Crohn's Disease Fibrosis by Down-Regulation of Fibroblast MMP Synthesis: A Role for Innate Lymphoid Cells?

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Bailey, Jennifer R ^a   Bland, Paul W ^a,b   Tarlton, John F ^a   Peters, Iain ^c   Moorghen, Moganaden ^d   Sylvester, Paul A ^e   Probert, Christopher S J ^f   Whiting, Christine V ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d ST MARK S HOSPITAL   (United Kingdom)

^e BRISTOL ROYAL INFIRMARY   (United Kingdom)

^f UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD45 ANTIGEN; CD56 ANTIGEN; COLLAGEN; GELATINASE A; GELATINASE B; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERSTITIAL COLLAGENASE; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; MATRIX METALLOPROTEINASE; STAT6 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CROHN DISEASE; DOWN REGULATION; ENZYME SYNTHESIS; FEMALE; FIBROBLAST; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; INTESTINAL FIBROSIS; INTESTINE MUSCLE; LYMPHOID CELL; MALE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ADOLESCENT; ADULT; AGED; COLLAGEN; CROHN DISEASE; DOWN-REGULATION; FEMALE; FIBROBLASTS; FIBROSIS; HUMANS; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTESTINAL MUCOSA; LYMPHOCYTES; MALE; MATRIX METALLOPROTEINASES; MIDDLE AGED; MUSCLES; YOUNG ADULT;

EID: 84871730586     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052332     Document Type: Article

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