Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel disease

Cytokine

Volumn 12, Issue 10, 2000, Pages 1531-1536

  Vainer, Ben ^a   Nielsen, Ole H ^a   Hendel, Jakob ^a   Horn, Thomas ^a   Kirman, Irena ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

Colon; Cytokines; Inflammatory bowel disease; Interleukin 13; Interleukin 15

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 15;

ADULT; AGED; ARTICLE; CELL INFILTRATION; COLON; COLON BIOPSY; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE EXACERBATION; DOWN REGULATION; ENTERITIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNITY; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; ULCERATIVE COLITIS;

EID: 0033790206     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0744     Document Type: Article

References (31)

1. Structural comparison and chromosomal localization of the human and mouse IL-13 genes
2. Modulation of expression of the anti-inflammatory cytokines interleukin-13 and interleukin-10 by interleukin-4
3. Effects of IL-13 on phenotype, cytokine production, and cytotoxid function of human monocytes
4. Regulatory effects of IL-13 on synovial fluid macrophages and blood monocytes from patients with inflammatory arthritis
5. Immunoregulatory properties of IL-13 in patients with inflammatory bowel disease; comparison with IL-14 and IL-10
6. Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for interleukins 2, 4, 7, 9, and 15
7. 4 and IgE synthesis and CD23 expression by human B cells
8. Expression of inducible nitric oxide synthase activity in human colon epithelial cells: Modulation by T lymphocyte derived cytokines
9. Regulation of human T lymphocyte chemotaxis in vitro by T cell-derived cytokines IL-2, IFN-γ, IL-4, IL-10, and IL-13
10. Interleukin-13 is a monocyte chemoattractant
11. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells
12. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: Priming for IL-12 and tumor necrosis factor α production
13. Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor
14. Induction and regulation of IL-15 expression in murine macrophages
15. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor
16. Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease
17. Chemoattraction of human blood T lymphocytes by interleukin-15
18. IL-10 synergizes with IL-4 and IL-13 in inhibiting lysosomal enzyme secretion by human monocytes and lamina propria mononuclear cells from patients with inflammatory bowel disease
19. In vivo expression of IL-12 and IL-13 in atopic dermatitis
20. Increased numbers of interleukin-15-expressing cells in active ulcerative colitis
21. Interleukin 15 mRNA transcripts in ulcerative colitis
22. CD4 + T lymphocytes injected into severe combined immunodeficient (SCID) mice lead to an inflammatory and lethal bowel disease
23. Investigation of cytokine mRNA production in the normal human intestinal mucosa
24. Irritable bowel syndrome
25. Serum antibodies to Bacteroides species in chronic inflammatory bowel disease
26. Serum concentration and chemotactic activity of E-selectin in inflammatory bowel disease
27. Circulating soluble intercellular adhesion molecule-1 (sICAM-1) in active inflammatory bowel disease
28. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses
29. Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides
30. Isolation and complete sequence of a functional human glyceraldehyd-3-phosphate dehydrogenase gene