Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase

American Journal of Physiology - Cell Physiology

Volumn 298, Issue 1, 2010, Pages

  Borradaile, Nica M ^b   Pickering, J Geoffrey ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Endothelial cells; Oxidative stress; Senescence

Indexed keywords

BUB1 RELATED PROTEIN; BUB1B RELATED PROTEIN; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN CCNE 2; CELL CYCLE PROTEIN CCNE 2A2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYTOKINE; CYTOKINE RECEPTOR; CYTOKINE RECEPTOR PTGS1; CYTOKINE RECEPTOR TNFRSF 21; INTERLEUKIN 32; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE COL5A1; MATRIX METALLOPROTEINASE FN1; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NOCODAZOLE; PROTEIN P107; REACTIVE OXYGEN METABOLITE; SIRTUIN 2; STROMELYSIN 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UNCLASSIFIED DRUG;

AORTA; APOPTOSIS; ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL DIVISION; CELL FUNCTION; CELL PROLIFERATION; CELL PROTECTION; CHROMOSOME DUPLICATION; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; OXIDATIVE STRESS; PHENOTYPE; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN INDUCTION; STIMULUS; TETRAPLOIDY;

AGING; AORTA; ATHEROSCLEROSIS; CELL CYCLE; CELL DIVISION; CYTOKINES; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENES, REPORTER; GLUCOSE; HUMANS; INFLAMMATION; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NOCODAZOLE; POLYPLOIDY;

EID: 73549125217     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00357.2009     Document Type: Article

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