메뉴 건너뛰기




Volumn 100, Issue 9, 1997, Pages 2182-2188

Genomic instability in the type II TGF-β1 receptor gene in atherosclerotic and restenotic vascular cells

Author keywords

Cardiovascular disease; DNA mutations; Microsatellite instability; Receptors; TGF

Indexed keywords

MICROSATELLITE DNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0030704297     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119754     Document Type: Article
Times cited : (161)

References (43)
  • 1
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (Lond.). 362:801-809.
    • (1993) Nature (Lond.) , vol.362 , pp. 801-809
    • Ross, R.1
  • 4
    • 0028903234 scopus 로고
    • Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques
    • Bennett, M.R., G.I. Evan, and S.M. Schwartz. 1995. Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J. Clin. Invest. 95:2266-2274.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2266-2274
    • Bennett, M.R.1    Evan, G.I.2    Schwartz, S.M.3
  • 5
    • 0030362608 scopus 로고    scopus 로고
    • Could atherosclerosis originate from defective smooth muscle cell death?
    • Rembold, C. 1996. Could atherosclerosis originate from defective smooth muscle cell death? Perspect. Biol. Med. 39:405-408.
    • (1996) Perspect. Biol. Med. , vol.39 , pp. 405-408
    • Rembold, C.1
  • 6
    • 0028859484 scopus 로고
    • Decreased Type II/Type I TGF-β1 receptor ratio in cells derived from human atherosclerotic lesions: Conversion from an antiproliferative to profibrotic response to TGF-β1
    • McCaffrey, T.A., S. Consigli, B. Du, D.J. Falcone, T.A. Sanborn, A.M. Spokojny, and H. Bush. 1995. Decreased Type II/Type I TGF-β1 receptor ratio in cells derived from human atherosclerotic lesions: conversion from an antiproliferative to profibrotic response to TGF-β1. J. Clin. Invest. 96:2667-2675.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2667-2675
    • McCaffrey, T.A.1    Consigli, S.2    Du, B.3    Falcone, D.J.4    Sanborn, T.A.5    Spokojny, A.M.6    Bush, H.7
  • 7
    • 0026450848 scopus 로고
    • Expression of transforming growth factor-β1 is increased in human vascular restenosis lesions
    • Nikol, S., J.M. Isner, J.G. Pickering, M. Kearney, G. Leclerc, and L. Weir. 1992. Expression of transforming growth factor-β1 is increased in human vascular restenosis lesions. J. Clin. Invest. 90:1582-1592.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1582-1592
    • Nikol, S.1    Isner, J.M.2    Pickering, J.G.3    Kearney, M.4    Leclerc, G.5    Weir, L.6
  • 8
    • 0025896187 scopus 로고
    • Lipoprotein (a) inhibits the generation of transforming growth factor-β: An endogenous inhibitor of smooth muscle cell migration
    • Kojima, S., P.C. Harpel, and D.B. Rifkin. 1991. Lipoprotein (a) inhibits the generation of transforming growth factor-β: an endogenous inhibitor of smooth muscle cell migration. J. Cell Biol. 113:1439-1445.
    • (1991) J. Cell Biol. , vol.113 , pp. 1439-1445
    • Kojima, S.1    Harpel, P.C.2    Rifkin, D.B.3
  • 10
    • 0027184395 scopus 로고
    • Tamoxifen decreases the rate of proliferation of rat vascular smooth-muscle cells in culture by inducing production of transforming growth factor β
    • Grainger, D.J., P.L. Weissberg, and J.C. Metcalfe. 1993. Tamoxifen decreases the rate of proliferation of rat vascular smooth-muscle cells in culture by inducing production of transforming growth factor β. Biochem. J. 294:109-112.
    • (1993) Biochem. J. , vol.294 , pp. 109-112
    • Grainger, D.J.1    Weissberg, P.L.2    Metcalfe, J.C.3
  • 11
    • 0027989926 scopus 로고
    • Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice
    • Grainger, D.J., P.R. Kemp, A.C. Liu, R.M. Lawn, and J.C. Metcalfe. 1994. Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice. Nature (Lond.). 370:460-462.
    • (1994) Nature (Lond.) , vol.370 , pp. 460-462
    • Grainger, D.J.1    Kemp, P.R.2    Liu, A.C.3    Lawn, R.M.4    Metcalfe, J.C.5
  • 13
    • 0025773216 scopus 로고
    • Effects of transforming growth factor-β1 on human arterial smooth muscle cells in vitro
    • Bjorkerud, S. 1991. Effects of transforming growth factor-β1 on human arterial smooth muscle cells in vitro. Arteriosclerosis. 11:892-902.
    • (1991) Arteriosclerosis , vol.11 , pp. 892-902
    • Bjorkerud, S.1
  • 14
    • 0027529271 scopus 로고
    • Evidence for an age-related dysfunction in the antiproliferative response to transforming growth factor-β in vascular smooth muscle cells
    • McCaffrey, T.A., and D.J. Falcone. 1993. Evidence for an age-related dysfunction in the antiproliferative response to transforming growth factor-β in vascular smooth muscle cells. Mol. Biol. Cell. 4:315-322.
    • (1993) Mol. Biol. Cell. , vol.4 , pp. 315-322
    • McCaffrey, T.A.1    Falcone, D.J.2
  • 17
    • 0029131403 scopus 로고
    • Demonstration that mutation of the Type II transforming growth factor receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
    • Wang, J., L.Z. Sun, L. Myeroff, X.F. Wang, L.E. Gentry, J. Yang, J. Liang, E. Zborowska, S. Markowitz, J.K.V. Willson, and M.G. Brattain. 1995. Demonstration that mutation of the Type II transforming growth factor receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J. Biol. Chem. 270:22044-22049.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22044-22049
    • Wang, J.1    Sun, L.Z.2    Myeroff, L.3    Wang, X.F.4    Gentry, L.E.5    Yang, J.6    Liang, J.7    Zborowska, E.8    Markowitz, S.9    Willson, J.K.V.10    Brattain, M.G.11
  • 18
    • 0029994532 scopus 로고    scopus 로고
    • Genetic diversity in colon carcinoma
    • Shibata, D., et al. 1996. Genetic diversity in colon carcinoma. Nat. Med. 2:676-681.
    • (1996) Nat. Med. , vol.2 , pp. 676-681
    • Shibata, D.1
  • 19
    • 0000874922 scopus 로고
    • Evidence for a monoclonal origin of human atherosclerotic plaques
    • Benditt, E.P., and J.M. Benditt. 1973. Evidence for a monoclonal origin of human atherosclerotic plaques. Proc. Natl. Acad. Sci. U.S.A. 70:1753-1756.
    • (1973) Proc. Natl. Acad. Sci. U.S.A. , vol.70 , pp. 1753-1756
    • Benditt, E.P.1    Benditt, J.M.2
  • 20
    • 0018154837 scopus 로고
    • Clonal markers in the study of the origin and growth of human atherosclerotic lesions
    • 11858
    • Pearson, T.A., J.M. Dillman, K. Soloz, and R.H. Heptinstall. 1978. Clonal markers in the study of the origin and growth of human atherosclerotic lesions. Circ. Res. 11858:28261-11380.
    • (1978) Circ. Res. , pp. 28261-111380
    • Pearson, T.A.1    Dillman, J.M.2    Soloz, K.3    Heptinstall, R.H.4
  • 22
    • 0029583514 scopus 로고
    • The intima: Development and monoclonal responses to injury
    • Schwartz, S.M., M.W. Majesky, and C.E. Murry. 1995. The intima: development and monoclonal responses to injury. Atherosclerosis. 118:s125-s140.
    • (1995) Atherosclerosis , vol.118
    • Schwartz, S.M.1    Majesky, M.W.2    Murry, C.E.3
  • 23
    • 0026537831 scopus 로고
    • Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
    • Lin, H.Y., X.F. Wang, E. Ng-Eaton, R.A. Weinberg, and H.F. Lodish. 1992. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell. 68:775-785.
    • (1992) Cell , vol.68 , pp. 775-785
    • Lin, H.Y.1    Wang, X.F.2    Ng-Eaton, E.3    Weinberg, R.A.4    Lodish, H.F.5
  • 25
    • 0027465080 scopus 로고
    • Mutant p53 tumor suppressor gene causes resistance to transforming growth factor β1 in murine keratinocytes
    • Reiss, M., V.F. Vellucci, and Z. Zhou. 1993. Mutant p53 tumor suppressor gene causes resistance to transforming growth factor β1 in murine keratinocytes. Cancer Res. 53:899-904.
    • (1993) Cancer Res. , vol.53 , pp. 899-904
    • Reiss, M.1    Vellucci, V.F.2    Zhou, Z.3
  • 27
    • 0029972674 scopus 로고
    • Heterozygote and mutation detection by direct automated fluorescent DNA sequencing using a mutant Taq DNA polymerase
    • Chadwick, R.B., M.P. Conrad, M.D. McGinnis, L. Johnston-Dow, S.L. Spurgeon, and M.N. Kronick. 1496. Heterozygote and mutation detection by direct automated fluorescent DNA sequencing using a mutant Taq DNA polymerase. Biotechniques. 20:676-683.
    • (1496) Biotechniques , vol.20 , pp. 676-683
    • Chadwick, R.B.1    Conrad, M.P.2    McGinnis, M.D.3    Johnston-Dow, L.4    Spurgeon, S.L.5    Kronick, M.N.6
  • 28
    • 0029793062 scopus 로고    scopus 로고
    • Genomic structure of the transforming growth factor beta type II receptor gene and its mutations in hereditary nonpolyposis colorectal cancers
    • Lu, S.-L., W.-C. Zhang, Y. Akiyama, T. Nomizu, and Y. Yuasa. 1996. Genomic structure of the transforming growth factor beta type II receptor gene and its mutations in hereditary nonpolyposis colorectal cancers. Cancer Res. 56: 4595-4598.
    • (1996) Cancer Res. , vol.56 , pp. 4595-4598
    • Lu, S.-L.1    Zhang, W.-C.2    Akiyama, Y.3    Nomizu, T.4    Yuasa, Y.5
  • 30
    • 0029098259 scopus 로고
    • Inhibition of capillary morphogenesis and associated apoptosis by dominant negative mutant transforming growth factor-β receptors
    • Choi, M.E., and B.J. Ballerman. 1995. Inhibition of capillary morphogenesis and associated apoptosis by dominant negative mutant transforming growth factor-β receptors. J. Biol. Chem. 270:21144-21150.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21144-21150
    • Choi, M.E.1    Ballerman, B.J.2
  • 31
    • 0024356385 scopus 로고
    • Transforming growth factor-β activity is potentiated by heparin via dissociation of the transforming growth-β/α2-macroglobulin inactive complex
    • McCaffrey, T.A., D.J. Falcone, C.F. Brayton, L.A. Agarwal, F.P. Welt, and B.B. Weksler. 1989. Transforming growth factor-β activity is potentiated by heparin via dissociation of the transforming growth-β/α2-macroglobulin inactive complex. J. Cell Biol. 109:441-448.
    • (1989) J. Cell Biol. , vol.109 , pp. 441-448
    • McCaffrey, T.A.1    Falcone, D.J.2    Brayton, C.F.3    Agarwal, L.A.4    Welt, F.P.5    Weksler, B.B.6
  • 32
    • 0026776936 scopus 로고
    • Transforming growth factor-β is a heparin-binding protein: Identification of putative heparin-binding regions and isolation of heparins with varying affinity for TGF-β1
    • McCaffrey, T.A., D.J. Falcone, and B. Du. 1992. Transforming growth factor-β is a heparin-binding protein: identification of putative heparin-binding regions and isolation of heparins with varying affinity for TGF-β1. J. Cell. Physiol. 152:430-440.
    • (1992) J. Cell. Physiol. , vol.152 , pp. 430-440
    • McCaffrey, T.A.1    Falcone, D.J.2    Du, B.3
  • 33
    • 85047678478 scopus 로고
    • Heparin decreases the rate of proliferation of rat vascular smooth muscle cells by releasing transforming growth factor β-like activity from serum
    • Grainger, D.J., C.M. Witchell, J.V. Watson, J.C. Metcalfe, and P.L. Weissberg. 1993. Heparin decreases the rate of proliferation of rat vascular smooth muscle cells by releasing transforming growth factor β-like activity from serum. Cardiovasc. Res. 27:2238-2247.
    • (1993) Cardiovasc. Res. , vol.27 , pp. 2238-2247
    • Grainger, D.J.1    Witchell, C.M.2    Watson, J.V.3    Metcalfe, J.C.4    Weissberg, P.L.5
  • 34
    • 0027471993 scopus 로고
    • Abnormal growth regulation of vascular smooth muscle cells by heparin in patients with restenosis
    • Chan, P., M. Patel, L. Betteridge, E. Munro, M. Schachter, J. Wolfe, and P. Sever. 1993. Abnormal growth regulation of vascular smooth muscle cells by heparin in patients with restenosis. Lancet (N. Am. Ed.). 341:341-342.
    • (1993) Lancet (N. Am. Ed.) , vol.341 , pp. 341-342
    • Chan, P.1    Patel, M.2    Betteridge, L.3    Munro, E.4    Schachter, M.5    Wolfe, J.6    Sever, P.7
  • 35
    • 0029902905 scopus 로고    scopus 로고
    • A mutation in the transforming growth factor β Type II receptor gene promoter associated with loss of gene expression
    • Munoz-Antonia, T., X. Li, M. Reiss, R. Jackson, and S. Antonia. 1996. A mutation in the transforming growth factor β Type II receptor gene promoter associated with loss of gene expression. Cancer Res. 56:4831-4835.
    • (1996) Cancer Res. , vol.56 , pp. 4831-4835
    • Munoz-Antonia, T.1    Li, X.2    Reiss, M.3    Jackson, R.4    Antonia, S.5
  • 36
    • 0030048263 scopus 로고    scopus 로고
    • Genetic change in transforming growth factor-β (TGF-β) receptor type 1 gene correlates with insensitivity to TGF-β1 in human prostate cancer cells
    • Kim, I.Y., H.J. Ahn. D.J. Zelner, J.W. Shaw, J.A. Sensibar, J.H. Kim, M. Kato, and C. Lee. 1996. Genetic change in transforming growth factor-β (TGF-β) receptor type 1 gene correlates with insensitivity to TGF-β1 in human prostate cancer cells. Cancer Res. 56:44-48.
    • (1996) Cancer Res. , vol.56 , pp. 44-48
    • Kim, I.Y.1    Ahn, H.J.2    Zelner, D.J.3    Shaw, J.W.4    Sensibar, J.A.5    Kim, J.H.6    Kato, M.7    Lee, C.8
  • 37
    • 0028088390 scopus 로고
    • An investigation of mutations as a function of age in humans
    • King, C.M., E.S. Gillespie, P.G. McKenna, and Y.A. Barnett. 1994. An investigation of mutations as a function of age in humans. Mutat. Res. 316:79-90.
    • (1994) Mutat. Res. , vol.316 , pp. 79-90
    • King, C.M.1    Gillespie, E.S.2    McKenna, P.G.3    Barnett, Y.A.4
  • 38
    • 0028049859 scopus 로고
    • Excision of ultraviolet-induced photoproducts of 5-methylcytosine from DNA
    • Vairapandi, M., and N.J. Duker. 1994. Excision of ultraviolet-induced photoproducts of 5-methylcytosine from DNA. Mutat. Res. 315:85-94.
    • (1994) Mutat. Res. , vol.315 , pp. 85-94
    • Vairapandi, M.1    Duker, N.J.2
  • 39
    • 0029121548 scopus 로고
    • Latent membrane protein-1 induces cyclin D2 expression, pRh hyperphosphorylation, and loss of TGF-β1-mediated growth inhibition in EBV-positive B cells
    • Arvanitakis, L., N. Yaseen, and S. Sharma. 1995. Latent membrane protein-1 induces cyclin D2 expression, pRh hyperphosphorylation, and loss of TGF-β1-mediated growth inhibition in EBV-positive B cells. J. Immunol. 155: 1047-1056.
    • (1995) J. Immunol. , vol.155 , pp. 1047-1056
    • Arvanitakis, L.1    Yaseen, N.2    Sharma, S.3
  • 41
    • 0342448452 scopus 로고
    • Report of the Working Group on Arteriosclerosis of the National Heart. Lung, and Blood Institute. NIH Publication. 81-2034
    • Arteriosclerosis 1981. Report of the Working Group on Arteriosclerosis of the National Heart. Lung, and Blood Institute. NIH Publication. 81-2034.
    • (1981) Arteriosclerosis
  • 43
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53
    • Denissenko, M.F., A. Pao, M.-S. Tang, and G.P. Pfeifer. 1996. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science (Wash. DC). 274:430-432.
    • (1996) Science (Wash. DC) , vol.274 , pp. 430-432
    • Denissenko, M.F.1    Pao, A.2    Tang, M.-S.3    Pfeifer, G.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.