메뉴 건너뛰기




Volumn 967, Issue , 2002, Pages 535-543

Acute elevation of NEFA causes hyperinsulinemia without effect on insulin secretion rate in healthy human subjects

Author keywords

C peptide; Free fatty acids; Insulin secretion; NEFA

Indexed keywords

C PEPTIDE; FATTY ACID; GLUCOSE; INSULIN; TRIACYLGLYCEROL;

EID: 0036299136     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04313.x     Document Type: Conference Paper
Times cited : (43)

References (22)
  • 2
    • 0023153344 scopus 로고
    • Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in noninsulin-dependent diabetes mellitus
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 17-21
    • Chen, Y.D.1
  • 3
  • 4
    • 0029948212 scopus 로고    scopus 로고
    • Mechanism of free fatty acid-induced insulin resistance in humans
    • (1996) J. Clin. Invest. , vol.97 , pp. 2859-2864
    • Roden, M.1
  • 5
    • 0029888870 scopus 로고    scopus 로고
    • Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat
    • (1996) J. Clin. Invest. , vol.97 , pp. 2728-2735
    • Stein, D.T.1
  • 6
    • 0032102146 scopus 로고    scopus 로고
    • A fatty acid-dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion
    • (1998) J. Clin. Invest. , vol.101 , pp. 2370-2376
    • Dobbins, R.L.1
  • 7
    • 0029046673 scopus 로고
    • Effects of a 48-h fat infusion on insulin secretion and glucose utilization
    • (1995) Diabetes , vol.44 , pp. 1239-1242
    • Boden, G.1
  • 8
    • 0031683543 scopus 로고    scopus 로고
    • Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
    • (1998) Diabetes , vol.47 , pp. 1613-1618
    • Dobbins, R.L.1
  • 9
    • 0031716376 scopus 로고    scopus 로고
    • Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and non-diabetic subjects
    • (1998) Diabetes , vol.47 , pp. 1609-1612
    • Boden, G.1
  • 10
    • 0031032274 scopus 로고    scopus 로고
    • Effects of free fatty acids and glucose on splanchnic insulin dynamics
    • (1997) Diabetes , vol.46 , pp. 57-62
    • Hennes, M.M.1
  • 11
    • 0032999260 scopus 로고    scopus 로고
    • Acute enhancement of insulin secretion by NEFA in humans is lost with prolonged FFA elevation
    • (1999) Am. J. Physiol. , vol.276
    • Carpentier, A.1
  • 12
    • 0034081782 scopus 로고    scopus 로고
    • Elevation of plasma fatty acids by ten-hour intralipid infusion has no effect on basal or glucose-stimulated insulin secretion in normal man
    • (2000) Metabolism , vol.49 , pp. 450-454
    • Amery, C.M.1
  • 13
    • 0034112066 scopus 로고    scopus 로고
    • Lack of effect of a physiological elevation of plasma nonesterified fatty acid levels on insulin secretion
    • (2000) Diabetes Metab , vol.26 , pp. 133-139
    • Frias, J.P.1
  • 14
    • 0028849148 scopus 로고
    • Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects
    • (1995) Diabetologia , vol.38 , pp. 1295-1299
    • Paolisso, G.1
  • 15
    • 0027319705 scopus 로고
    • Analysis of techniques to obtain plasma for measurement of levels of free fatty acids
    • (1993) J. Lipid Res. , vol.34 , pp. 1021-1022
    • Zambon, A.1
  • 16
    • 0022572232 scopus 로고
    • Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients
    • (1986) J. Clin. Invest. , vol.77 , pp. 98-105
    • Polonsky, K.1
  • 18
  • 19
    • 0025296906 scopus 로고
    • Free fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes
    • (1990) Diabetes , vol.39 , pp. 570-574
    • Svedberg, J.1
  • 20
    • 0026341637 scopus 로고
    • Fatty acids in the portal vein of the rat regulate hepatic insulin clearance
    • (1991) J. Clin. Invest. , vol.88 , pp. 2054-2058
    • Svedberg, J.1
  • 22
    • 0034982369 scopus 로고    scopus 로고
    • Decreased susceptibility to fatty acid-induced peripheral tissue insulin resistance in women
    • (2001) Diabetes , vol.50 , pp. 1344-1350
    • Frias, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.