Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice

Journal of Immunology

Volumn 182, Issue 6, 2009, Pages 3492-3502

  Blair, Paul A ^a   Chavez Rueda, Karina A ^a,b   Evans, Jamie G ^a   Shlomchik, Mark J ^c   Eddaoudi, Ayad ^d   Isenberg, David A ^a   Ehrenstein, Michael R ^a   Mauri, Claudia ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b HOSPITAL DE PEDIATRÍA   (Mexico)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD40 ANTIBODY; FGK 45; INTERLEUKIN 10; UNCLASSIFIED DRUG; CD40 ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY DISEASE; LUPUS LIKE SYNDROME; LYMPHOCYTE TRANSFER; MOUSE; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SURVIVAL; TH1 CELL; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG POTENTIATION; IMMUNOLOGY; LYMPHOCYTE COUNT; PATHOLOGY; SYSTEMIC LUPUS ERYTHEMATOSUS; TRANSGENIC MOUSE; TRANSPLANTATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD40; B-LYMPHOCYTE SUBSETS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE COUNT; MICE; MICE, INBRED C57BL; MICE, INBRED MRL LPR; MICE, TRANSGENIC; TH1 CELLS;

EID: 65449188259     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803052     Document Type: Article

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