B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)

Clinical and Experimental Immunology

Volumn 111, Issue 3, 1998, Pages 521-526

  Svensson, L ^a   Jirholt, J ^a   Holmdahl, R ^a   Jansson, L ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Autoimmunity; B cells; Collagen induced arthritis; Type II collagen

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CATTLE; COLLAGEN DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; B-LYMPHOCYTES; CATTLE; COLLAGEN; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; RATS; T-LYMPHOCYTES;

EID: 0031899715     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00529.x     Document Type: Article

References (41)

1. Nepom GT, Byers P, Seyfried C, Healey LA, Wilske KR, Stage D, Nepom BS. HLA genes associated with rheumatoid arthritis. Identification of susceptibility alleles using specific oligonucleotide probes. Arthritis Rheum 1989; 32:15-21.
2. Londei M, Savill CM, Verhoef A, Brennan F, Leech ZA, Duance V, Maini RN, Feldmann M. Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis. Proc Natl Acad Sci USA 1989; 86:636-40.
3. Pereira RS, Black CM, Duance VC, Jones VE, Jacoby RK, Welsh KI. Disappearing collagen antibodies in rheumatoid arthritis. Lancet 1985; 2:501-2.
4. Tarkowski A, Klareskog L, Carlsten H, Herberts P, Koopman WJ. Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritis. Arthritis Rheum 1989; 32:1087-92.
5. Rowley M. Tait B, Mackay IR, Cunningham T, Phillips B. Collagen antibodies in rheumatoid arthritis. Significance of antibodies to denatured collagen and their association with HLA-DR4. Arthritis Rheum 1986; 29:174-84.
6. Ronnelid J, Lysholm J, Engstrom-Laurent A, Klareskog L, Heyman B. Local anti-type II collagen antibody production in rheumatoid arthritis synovial fluid. Evidence for an HLA-DR4-restricted IgG response. Arthritis Rheum 1994; 37:1023-9.
7. Trentham DE, Townes AS, Kang AH. Autoimmunity to type II collagen: an experimental model of arthritis. J Exp Med 1977; 146:857-68.
8. Courtenay JS, Dallman MJ, Dayan AD, Martin A, Mosedale B. Immunization against heterologous type II collagen induces arthritis in mice. Nature 1980; 283:666-8.
9. Holmdahl R, Vingsbo C, Mo JA, Michaëlsson E, Malmström V, Jansson L, Brunsberg U. Chronicity of tissue-specific experimental autoimmune disease: a role for B cells? Immunol Rev 1995; 144:109-35.
10. Wooley PH, Luthra HS, Stuart JM, David SC. Type II collagen induced arthritis in mice. I. Major histocompatibility complex (I-region) linkage and antibody correlates. J Exp Med 1981; 154:688-700.
11. Brunsberg U, Gustafson K, Jansson L, Michaëlsson E, Ährlund-Richter L, Pettersson S, Mattsson R, Holmdahl R. Expression of transgenic class II Ab gene confers susceptibility to collagen-induced arthritis. Eur J Immunol 1994; 24:1698-702.
12. Trentham DE, Dynesius-Trentham RA, Orav JE, Combitchi D, Lorenzo C, Seawell KL, Hafler DA, Weiner HL. Effects of oral administration of type II collagen on rheumatoid arthritis. Sci 1993; 261:1727-30.
13. Zhang ZJ, Lee CSY, Lider O, Weiner HL. Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen. J Immunol 1990; 145:2489-93.
14. Holmdahl R, Jansson L, Gullberg D, Rubin K, Forsberg PO, Klareskog L. Incidence of arthritis and autoreactivity of anti-collagen antibodies after immunization of DBA/1 mice with heterologous and autologous collagen II. Clin Exp Immunol 1985; 62:639-46.
15. Mo J, Scheynius A, Holmdahl R. Antibody recognition of mouse cartilage in vivo; epitope- and idiotype-specific binding and inhibition. Scand J Immunol 1994; 39:122-30.
16. Stuart JM, Dixon FJ. Serum transfer of collagen induced arthritis in mice. J Exp Med 1983; 158:378-92.
17. Holmdahl R, Jansson L, Larsson A, Jonsson R. Arthritis in DBA/1 mice induced with passively transferred type II collagen immune serum. Immunohistopathology and serum levels of anti-type II collagen autoantibodies. Scand J Immunol 1990; 31:147-57.
18. Holmdahl R, Vingsbo C, Malmström V, Jansson L, Holmdahl M. Chronicity of arthritis induced with homologous type II collagen (CII) in rats is dependent on anti-CII B-cell activation. J Autoimmun 1994; 7:739-52.
19. Seki N, Sudo Y, Yoshioka T et al. Type II collagen induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. J Immunol 1988; 140:1477-84.
20. Holmdahl R, Jansson L, Larsson E, Rubin K, Klareskog L. Homologous type II collagen induces chronic and progressive arthritis in mice. Arthritis Rheum 1986; 29:106-13.
21. Reife RA, Loutis N, Watson WC, Hasty KA, Stuart JM. SWR mice are resistant to collagen-induced arthritis but produce potentially arthritogenic antibodies. Arthritis Rheum 1991; 34:776-81.
22. Kitamura D, Roes J, Kühn R, Rajewsky K. A B cell deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 1991; 350:423-6.
23. Miller ES. Structural studies on cartilage employing limited cleavage and solubilization with pepsin. Biochem 1972: 11:4901-9.
24. Holmdahl R, Klareskog L, Andersson M, Hansen C. High antibody response to autologous type II collagen is restricted to H-2q. Immunogenetics 1986; 24:84-89.
25. Michaelsson E, Andersson M, Engström Å, Holmdahl R. Identification of an immunodominant type II collagen peptide recognized by T-cells in H-2q mice; self tolerance at the level of determinant selection. Eur J Immunol 1992; 22:1819-25.
26. Miyahara H, Myers LK, Rosloniec EF, Brand DD, Seyer JM, Stuart JM, Kang AH. Identification and characterization of a major tolerogenic T-cell epitope of type II collagen that suppresses arthritis in B10.RIII mice. Immunol 1995; 86:110-5.
27. Terato K, Hasty KA, Reife RA, Cremer MA, Kang AH, Stuart JM. Induction of arthritis with monoclonal antibodies to collagen. J Immunol 1992; 148:2103-8.
28. Helfgott SM, Bazin H, Dessein A, Trentham DE. Suppressive effects of anti-μ serum on the development of collagen arthritis in rat. Clin Immunol Immunopathol 1984; 31:403-11.
29. Myers KJ, Sprent J, Dougherty JP, Ron Y. Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis. J Neuroimmunol 1992; 41:1-8.
30. Wolf SD, Dittel BN, Hardardottir F, Janeway CA Jr. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med 1996; 184:2271-8.
31. Morgan K, Clague RB, Shaw MJ, Firth SA, Twose TM, Holt PJL. Native type II collagen-induced arthritis in the rat. The effect of complement depletion by cobra venom factor. Arthritis Rheum 1981; 24:1356-62.
32. Wang Y, Rollins SA, Madri JA, Matis LA. Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease. Proc Natl Acad Sci USA 1995; 92:8955-9.
33. Dempsey PW, Allison ME, Akkaraju S, Goodnow CC, Fearon DT. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. Sci 1996; 271:348-50.
34. Thomas JD, Sideras P, Smith CI, Vorechovsky I, Chapman V, Paul WE. Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Sci 1993; 261:355-8.
35. Rawlings DJ, Saffran DC, Tsukada S et al. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Sci 1993; 261:358-61.
36. Jansson L, Olsson T, Holmdahl R. Influence by T cell receptor genes on chronic experimental autoimmune encephalomyelitis. Immunogenetics 1993; 37:466-8.
37. Jansson L, Holmdahl R. The Y chromosome-linked ëautoimmune accelerating' yaa gene suppresses collagen induced arthritis. Eur J Immunol 1994; 24:1213-7.
38. Epstein MM, Di Rosa F, Jankovic D, Sher A, Matzinger P. Successful T cell priming in B cell-deficient mice. J Exp Med 1995; 182:915-22.
39. Thomsen AR, Johansen J, Marker O, Christensen JP. Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice. J Immunol 1996; 157:3074-80.
40. + T cell activation and tolerance induction in B cell knockout mice. J Exp Med 1996; 183:1339-44.
41. + T cells play a role in initiation and regulate recovery phase of collagen-induced arthritis. J Immunol 1996; 156:4520-6.