메뉴 건너뛰기




Volumn 7, Issue 12, 2012, Pages

Ofd1 Controls Dorso-Ventral Patterning and Axoneme Elongation during Embryonic Brain Development

Author keywords

[No Author keywords available]

Indexed keywords

NEUROGENIN 2; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR PAX6;

EID: 84871661888     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052937     Document Type: Article
Times cited : (29)

References (93)
  • 1
    • 49949107386 scopus 로고    scopus 로고
    • The genetics of early telencephalon patterning: some assembly required
    • Hebert JM, Fishell G, (2008) The genetics of early telencephalon patterning: some assembly required. Nat Rev Neurosci 9: 678-685.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 678-685
    • Hebert, J.M.1    Fishell, G.2
  • 2
    • 34848902919 scopus 로고    scopus 로고
    • Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool
    • Chizhikov VV, Davenport J, Zhang Q, Shih EK, Cabello OA, et al. (2007) Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool. J Neurosci 27: 9780-9789.
    • (2007) J Neurosci , vol.27 , pp. 9780-9789
    • Chizhikov, V.V.1    Davenport, J.2    Zhang, Q.3    Shih, E.K.4    Cabello, O.A.5
  • 4
    • 39749112475 scopus 로고    scopus 로고
    • Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells
    • Han YG, Spassky N, Romaguera-Ros M, Garcia-Verdugo JM, Aguilar A, et al. (2008) Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells. Nat Neurosci 11: 277-284.
    • (2008) Nat Neurosci , vol.11 , pp. 277-284
    • Han, Y.G.1    Spassky, N.2    Romaguera-Ros, M.3    Garcia-Verdugo, J.M.4    Aguilar, A.5
  • 5
    • 42649103998 scopus 로고    scopus 로고
    • Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool
    • Spassky N, Han YG, Aguilar A, Strehl L, Besse L, et al. (2008) Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool. Dev Biol 317: 246-259.
    • (2008) Dev Biol , vol.317 , pp. 246-259
    • Spassky, N.1    Han, Y.G.2    Aguilar, A.3    Strehl, L.4    Besse, L.5
  • 6
    • 76749119957 scopus 로고    scopus 로고
    • Role of primary cilia in brain development and cancer
    • Han YG, Alvarez-Buylla A, (2010) Role of primary cilia in brain development and cancer. Curr Opin Neurobiol 20: 58-67.
    • (2010) Curr Opin Neurobiol , vol.20 , pp. 58-67
    • Han, Y.G.1    Alvarez-Buylla, A.2
  • 7
    • 79953047750 scopus 로고    scopus 로고
    • Cilia in the nervous system: linking cilia function and neurodevelopmental disorders
    • Lee JE, Gleeson JG, (2011) Cilia in the nervous system: linking cilia function and neurodevelopmental disorders. Curr Opin Neurol 24: 98-105.
    • (2011) Curr Opin Neurol , vol.24 , pp. 98-105
    • Lee, J.E.1    Gleeson, J.G.2
  • 11
    • 77951101203 scopus 로고    scopus 로고
    • The primary cilium: a signalling centre during vertebrate development
    • Goetz SC, Anderson KV, (2010) The primary cilium: a signalling centre during vertebrate development. Nat Rev Genet 11: 331-344.
    • (2010) Nat Rev Genet , vol.11 , pp. 331-344
    • Goetz, S.C.1    Anderson, K.V.2
  • 13
    • 57849164934 scopus 로고    scopus 로고
    • Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain
    • Gorivodsky M, Mukhopadhyay M, Wilsch-Braeuninger M, Phillips M, Teufel A, et al. (2009) Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain. Dev Biol 325: 24-32.
    • (2009) Dev Biol , vol.325 , pp. 24-32
    • Gorivodsky, M.1    Mukhopadhyay, M.2    Wilsch-Braeuninger, M.3    Phillips, M.4    Teufel, A.5
  • 14
    • 70349783742 scopus 로고    scopus 로고
    • Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain
    • Stottmann RW, Tran PV, Turbe-Doan A, Beier DR, (2009) Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol 335: 166-178.
    • (2009) Dev Biol , vol.335 , pp. 166-178
    • Stottmann, R.W.1    Tran, P.V.2    Turbe-Doan, A.3    Beier, D.R.4
  • 15
    • 79955557285 scopus 로고    scopus 로고
    • Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing
    • Besse L, Neti M, Anselme I, Gerhardt C, Ruther U, et al. (2011) Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing. Development 138: 2079-2088.
    • (2011) Development , vol.138 , pp. 2079-2088
    • Besse, L.1    Neti, M.2    Anselme, I.3    Gerhardt, C.4    Ruther, U.5
  • 17
    • 79952770440 scopus 로고    scopus 로고
    • Cilia in the CNS: The Quiet Organelle Claims Center Stage
    • Louvi A, Grove EA, (2011) Cilia in the CNS: The Quiet Organelle Claims Center Stage. Neuron 69: 1046-1060.
    • (2011) Neuron , vol.69 , pp. 1046-1060
    • Louvi, A.1    Grove, E.A.2
  • 18
    • 70449672808 scopus 로고    scopus 로고
    • The molecular basis of oral-facial-digital syndrome, type 1
    • Macca M, Franco B, (2009) The molecular basis of oral-facial-digital syndrome, type 1. Am J Med Genet C Semin Med Genet 151C: 318-325.
    • (2009) Am J Med Genet C Semin Med Genet , vol.151 C , pp. 318-325
    • Macca, M.1    Franco, B.2
  • 19
    • 47149086389 scopus 로고    scopus 로고
    • Dosage compensation of the mammalian X chromosome influences the phenotypic variability of X-linked dominant male-lethal disorders
    • Morleo M, Franco B, (2008) Dosage compensation of the mammalian X chromosome influences the phenotypic variability of X-linked dominant male-lethal disorders. J Med Genet 45: 401-408.
    • (2008) J Med Genet , vol.45 , pp. 401-408
    • Morleo, M.1    Franco, B.2
  • 20
    • 55349129995 scopus 로고    scopus 로고
    • Mutational spectrum of the oral-facial-digital type I syndrome: a study on a large collection of patients
    • Prattichizzo C, Macca M, Novelli V, Giorgio G, Barra A, et al. (2008) Mutational spectrum of the oral-facial-digital type I syndrome: a study on a large collection of patients. Hum Mutat 29: 1237-1246.
    • (2008) Hum Mutat , vol.29 , pp. 1237-1246
    • Prattichizzo, C.1    Macca, M.2    Novelli, V.3    Giorgio, G.4    Barra, A.5
  • 22
    • 16644375931 scopus 로고    scopus 로고
    • OFD1 is a centrosomal/basal body protein expressed during mesenchymal-epithelial transition in human nephrogenesis
    • Romio L, Fry AM, Winyard PJ, Malcolm S, Woolf AS, et al. (2004) OFD1 is a centrosomal/basal body protein expressed during mesenchymal-epithelial transition in human nephrogenesis. J Am Soc Nephrol 15: 2556-2568.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2556-2568
    • Romio, L.1    Fry, A.M.2    Winyard, P.J.3    Malcolm, S.4    Woolf, A.S.5
  • 23
    • 35848941930 scopus 로고    scopus 로고
    • Functional characterization of the OFD1 protein reveals a nuclear localization and physical interaction with subunits of a chromatin remodeling complex
    • Giorgio G, Alfieri M, Prattichizzo C, Zullo A, Cairo S, et al. (2007) Functional characterization of the OFD1 protein reveals a nuclear localization and physical interaction with subunits of a chromatin remodeling complex. Mol Biol Cell 18: 4397-4404.
    • (2007) Mol Biol Cell , vol.18 , pp. 4397-4404
    • Giorgio, G.1    Alfieri, M.2    Prattichizzo, C.3    Zullo, A.4    Cairo, S.5
  • 24
    • 29444439981 scopus 로고    scopus 로고
    • Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification
    • Ferrante MI, Zullo A, Barra A, Bimonte S, Messaddeq N, et al. (2006) Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet 38: 112-117.
    • (2006) Nat Genet , vol.38 , pp. 112-117
    • Ferrante, M.I.1    Zullo, A.2    Barra, A.3    Bimonte, S.4    Messaddeq, N.5
  • 25
    • 84862654933 scopus 로고    scopus 로고
    • Joubert syndrome: brain and spinal cord malformations in genotyped cases and implications for neurodevelopmental functions of primary cilia
    • Juric-Sekhar G, Adkins J, Doherty D, Hevner RF, (2012) Joubert syndrome: brain and spinal cord malformations in genotyped cases and implications for neurodevelopmental functions of primary cilia. Acta Neuropathol 123: 695-709.
    • (2012) Acta Neuropathol , vol.123 , pp. 695-709
    • Juric-Sekhar, G.1    Adkins, J.2    Doherty, D.3    Hevner, R.F.4
  • 26
    • 0038700741 scopus 로고    scopus 로고
    • Characterization of the OFD1/Ofd1 genes on the human and mouse sex chromosomes and exclusion of Ofd1 for the Xpl mouse mutant
    • Ferrante MI, Barra A, Truong JP, Banfi S, Disteche CM, et al. (2003) Characterization of the OFD1/Ofd1 genes on the human and mouse sex chromosomes and exclusion of Ofd1 for the Xpl mouse mutant. Genomics 81: 560-569.
    • (2003) Genomics , vol.81 , pp. 560-569
    • Ferrante, M.I.1    Barra, A.2    Truong, J.P.3    Banfi, S.4    Disteche, C.M.5
  • 27
    • 0033967842 scopus 로고    scopus 로고
    • A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons
    • Fode C, Ma Q, Casarosa S, Ang SL, Anderson DJ, et al. (2000) A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev 14: 67-80.
    • (2000) Genes Dev , vol.14 , pp. 67-80
    • Fode, C.1    Ma, Q.2    Casarosa, S.3    Ang, S.L.4    Anderson, D.J.5
  • 28
    • 0036844682 scopus 로고    scopus 로고
    • Pax6; a pleiotropic player in development
    • Simpson TI, Price DJ, (2002) Pax6; a pleiotropic player in development. Bioessays 24: 1041-1051.
    • (2002) Bioessays , vol.24 , pp. 1041-1051
    • Simpson, T.I.1    Price, D.J.2
  • 29
    • 42649091463 scopus 로고    scopus 로고
    • Characterization of the proneural gene regulatory network during mouse telencephalon development
    • Gohlke JM, Armant O, Parham FM, Smith MV, Zimmer C, et al. (2008) Characterization of the proneural gene regulatory network during mouse telencephalon development. BMC Biol 6: 15.
    • (2008) BMC Biol , vol.6 , pp. 15
    • Gohlke, J.M.1    Armant, O.2    Parham, F.M.3    Smith, M.V.4    Zimmer, C.5
  • 30
    • 67650002531 scopus 로고    scopus 로고
    • Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice
    • Tuoc TC, Radyushkin K, Tonchev AB, Pinon MC, Ashery-Padan R, et al. (2009) Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci 29: 8335-8349.
    • (2009) J Neurosci , vol.29 , pp. 8335-8349
    • Tuoc, T.C.1    Radyushkin, K.2    Tonchev, A.B.3    Pinon, M.C.4    Ashery-Padan, R.5
  • 31
    • 77956470521 scopus 로고    scopus 로고
    • Investigating gradients of gene expression involved in early human cortical development
    • Ip BK, Wappler I, Peters H, Lindsay S, Clowry GJ, et al. (2010) Investigating gradients of gene expression involved in early human cortical development. J Anat 217: 300-311.
    • (2010) J Anat , vol.217 , pp. 300-311
    • Ip, B.K.1    Wappler, I.2    Peters, H.3    Lindsay, S.4    Clowry, G.J.5
  • 32
    • 38349195409 scopus 로고    scopus 로고
    • Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate
    • Mangale VS, Hirokawa KE, Satyaki PR, Gokulchandran N, Chikbire S, et al. (2008) Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate. Science 319: 304-309.
    • (2008) Science , vol.319 , pp. 304-309
    • Mangale, V.S.1    Hirokawa, K.E.2    Satyaki, P.R.3    Gokulchandran, N.4    Chikbire, S.5
  • 33
    • 0032831113 scopus 로고    scopus 로고
    • Mouse Wnt8B is expressed in the developing forebrain and maps to chromosome 19
    • Richardson M, Redmond D, Watson CJ, Mason JO, (1999) Mouse Wnt8B is expressed in the developing forebrain and maps to chromosome 19. Mamm Genome 10: 923-925.
    • (1999) Mamm Genome , vol.10 , pp. 923-925
    • Richardson, M.1    Redmond, D.2    Watson, C.J.3    Mason, J.O.4
  • 34
    • 73949153021 scopus 로고    scopus 로고
    • Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon
    • Fotaki V, Larralde O, Zeng S, McLaughlin D, Nichols J, et al. (2010) Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn 239: 284-296.
    • (2010) Dev Dyn , vol.239 , pp. 284-296
    • Fotaki, V.1    Larralde, O.2    Zeng, S.3    McLaughlin, D.4    Nichols, J.5
  • 35
    • 12144266963 scopus 로고    scopus 로고
    • Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex
    • Englund C, Fink A, Lau C, Pham D, Daza RA, et al. (2005) Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci 25: 247-251.
    • (2005) J Neurosci , vol.25 , pp. 247-251
    • Englund, C.1    Fink, A.2    Lau, C.3    Pham, D.4    Daza, R.A.5
  • 36
    • 53049083077 scopus 로고    scopus 로고
    • Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex
    • Sessa A, Mao CA, Hadjantonakis AK, Klein WH, Broccoli V, (2008) Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Neuron 60: 56-69.
    • (2008) Neuron , vol.60 , pp. 56-69
    • Sessa, A.1    Mao, C.A.2    Hadjantonakis, A.K.3    Klein, W.H.4    Broccoli, V.5
  • 37
    • 17744398634 scopus 로고    scopus 로고
    • Tbr1 regulates differentiation of the preplate and layer 6
    • Hevner RF, Shi L, Justice N, Hsueh Y, Sheng M, et al. (2001) Tbr1 regulates differentiation of the preplate and layer 6. Neuron 29: 353-366.
    • (2001) Neuron , vol.29 , pp. 353-366
    • Hevner, R.F.1    Shi, L.2    Justice, N.3    Hsueh, Y.4    Sheng, M.5
  • 38
    • 77955642202 scopus 로고    scopus 로고
    • Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
    • Bedogni F, Hodge RD, Elsen GE, Nelson BR, Daza RA, et al. (2010) Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Proc Natl Acad Sci U S A 107: 13129-13134.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13129-13134
    • Bedogni, F.1    Hodge, R.D.2    Elsen, G.E.3    Nelson, B.R.4    Daza, R.A.5
  • 39
    • 0034537678 scopus 로고    scopus 로고
    • The Gsh2 homeodomain gene controls multiple aspects of telencephalic development
    • Corbin JG, Gaiano N, Machold RP, Langston A, Fishell G, (2000) The Gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development 127: 5007-5020.
    • (2000) Development , vol.127 , pp. 5007-5020
    • Corbin, J.G.1    Gaiano, N.2    Machold, R.P.3    Langston, A.4    Fishell, G.5
  • 40
    • 4544298324 scopus 로고    scopus 로고
    • The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon
    • Waclaw RR, Wang B, Campbell K, (2004) The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development 131: 4013-4020.
    • (2004) Development , vol.131 , pp. 4013-4020
    • Waclaw, R.R.1    Wang, B.2    Campbell, K.3
  • 41
    • 59049084200 scopus 로고    scopus 로고
    • Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways
    • Long JE, Swan C, Liang WS, Cobos I, Potter GB, et al. (2009) Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol 512: 556-572.
    • (2009) J Comp Neurol , vol.512 , pp. 556-572
    • Long, J.E.1    Swan, C.2    Liang, W.S.3    Cobos, I.4    Potter, G.B.5
  • 42
    • 77955732889 scopus 로고    scopus 로고
    • Conserved and novel roles for the Gsh2 transcription factor in primary neurogenesis
    • Winterbottom EF, Illes JC, Faas L, Isaacs HV, (2010) Conserved and novel roles for the Gsh2 transcription factor in primary neurogenesis. Development 137: 2623-2631.
    • (2010) Development , vol.137 , pp. 2623-2631
    • Winterbottom, E.F.1    Illes, J.C.2    Faas, L.3    Isaacs, H.V.4
  • 43
    • 79952131882 scopus 로고    scopus 로고
    • Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation
    • Pei Z, Wang B, Chen G, Nagao M, Nakafuku M, et al. (2011) Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation. Proc Natl Acad Sci U S A 108: 1675-1680.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 1675-1680
    • Pei, Z.1    Wang, B.2    Chen, G.3    Nagao, M.4    Nakafuku, M.5
  • 44
    • 0027479055 scopus 로고
    • The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos
    • Bulfone A, Kim HJ, Puelles L, Porteus MH, Grippo JF, et al. (1993) The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mech Dev 40: 129-140.
    • (1993) Mech Dev , vol.40 , pp. 129-140
    • Bulfone, A.1    Kim, H.J.2    Puelles, L.3    Porteus, M.H.4    Grippo, J.F.5
  • 45
    • 0027232546 scopus 로고
    • Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries
    • Bulfone A, Puelles L, Porteus MH, Frohman MA, Martin GR, et al. (1993) Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J Neurosci 13: 3155-3172.
    • (1993) J Neurosci , vol.13 , pp. 3155-3172
    • Bulfone, A.1    Puelles, L.2    Porteus, M.H.3    Frohman, M.A.4    Martin, G.R.5
  • 46
    • 0032841612 scopus 로고    scopus 로고
    • Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum
    • Sussel L, Marin O, Kimura S, Rubenstein JL, (1999) Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development 126: 3359-3370.
    • (1999) Development , vol.126 , pp. 3359-3370
    • Sussel, L.1    Marin, O.2    Kimura, S.3    Rubenstein, J.L.4
  • 47
    • 0030008913 scopus 로고    scopus 로고
    • Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse
    • Shoji H, Ito T, Wakamatsu Y, Hayasaka N, Ohsaki K, et al. (1996) Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech Dev 56: 25-39.
    • (1996) Mech Dev , vol.56 , pp. 25-39
    • Shoji, H.1    Ito, T.2    Wakamatsu, Y.3    Hayasaka, N.4    Ohsaki, K.5
  • 49
    • 0014097059 scopus 로고
    • Extra-toes: anew mutant gene causing multiple abnormalities in the mouse
    • Johnson DR, (1967) Extra-toes: anew mutant gene causing multiple abnormalities in the mouse. J Embryol Exp Morphol 17: 543-581.
    • (1967) J Embryol Exp Morphol , vol.17 , pp. 543-581
    • Johnson, D.R.1
  • 50
    • 0032872508 scopus 로고    scopus 로고
    • Gli3 is required for Emx gene expression during dorsal telencephalon development
    • Theil T, Alvarez-Bolado G, Walter A, Ruther U, (1999) Gli3 is required for Emx gene expression during dorsal telencephalon development. Development 126: 3561-3571.
    • (1999) Development , vol.126 , pp. 3561-3571
    • Theil, T.1    Alvarez-Bolado, G.2    Walter, A.3    Ruther, U.4
  • 51
    • 0034650621 scopus 로고    scopus 로고
    • Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)
    • Tole S, Ragsdale CW, Grove EA, (2000) Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol 217: 254-265.
    • (2000) Dev Biol , vol.217 , pp. 254-265
    • Tole, S.1    Ragsdale, C.W.2    Grove, E.A.3
  • 52
    • 33748479706 scopus 로고    scopus 로고
    • Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3
    • Fotaki V, Yu T, Zaki PA, Mason JO, Price DJ, (2006) Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3. J Neurosci 26: 9282-9292.
    • (2006) J Neurosci , vol.26 , pp. 9282-9292
    • Fotaki, V.1    Yu, T.2    Zaki, P.A.3    Mason, J.O.4    Price, D.J.5
  • 53
    • 0027478216 scopus 로고
    • A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
    • Hui CC, Joyner AL, (1993) A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3: 241-246.
    • (1993) Nat Genet , vol.3 , pp. 241-246
    • Hui, C.C.1    Joyner, A.L.2
  • 54
    • 0242581681 scopus 로고    scopus 로고
    • Hedgehog signalling in the mouse requires intraflagellar transport proteins
    • Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, et al. (2003) Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-87.
    • (2003) Nature , vol.426 , pp. 83-87
    • Huangfu, D.1    Liu, A.2    Rakeman, A.S.3    Murcia, N.S.4    Niswander, L.5
  • 55
    • 23844485210 scopus 로고    scopus 로고
    • Cilia and Hedgehog responsiveness in the mouse
    • Huangfu D, Anderson KV, (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-11330.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11325-11330
    • Huangfu, D.1    Anderson, K.V.2
  • 56
    • 40749144679 scopus 로고    scopus 로고
    • Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
    • Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, et al. (2005) Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 1: e53.
    • (2005) PLoS Genet , vol.1
    • Haycraft, C.J.1    Banizs, B.2    Aydin-Son, Y.3    Zhang, Q.4    Michaud, E.J.5
  • 57
    • 23144466931 scopus 로고    scopus 로고
    • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
    • Liu A, Wang B, Niswander LA, (2005) Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132: 3103-3111.
    • (2005) Development , vol.132 , pp. 3103-3111
    • Liu, A.1    Wang, B.2    Niswander, L.A.3
  • 58
    • 27744484694 scopus 로고    scopus 로고
    • Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
    • May SR, Ashique AM, Karlen M, Wang B, Shen Y, et al. (2005) Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biol 287: 378-389.
    • (2005) Dev Biol , vol.287 , pp. 378-389
    • May, S.R.1    Ashique, A.M.2    Karlen, M.3    Wang, B.4    Shen, Y.5
  • 59
    • 34547800833 scopus 로고    scopus 로고
    • Ftm is a novel basal body protein of cilia involved in Shh signalling
    • Vierkotten J, Dildrop R, Peters T, Wang B, Ruther U, (2007) Ftm is a novel basal body protein of cilia involved in Shh signalling. Development 134: 2569-2577.
    • (2007) Development , vol.134 , pp. 2569-2577
    • Vierkotten, J.1    Dildrop, R.2    Peters, T.3    Wang, B.4    Ruther, U.5
  • 60
    • 41349107244 scopus 로고    scopus 로고
    • THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
    • Tran PV, Haycraft CJ, Besschetnova TY, Turbe-Doan A, Stottmann RW, et al. (2008) THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. Nat Genet 40: 403-410.
    • (2008) Nat Genet , vol.40 , pp. 403-410
    • Tran, P.V.1    Haycraft, C.J.2    Besschetnova, T.Y.3    Turbe-Doan, A.4    Stottmann, R.W.5
  • 61
    • 38049092146 scopus 로고    scopus 로고
    • Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain
    • Bishop GA, Berbari NF, Lewis J, Mykytyn K, (2007) Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain. J Comp Neurol 505: 562-571.
    • (2007) J Comp Neurol , vol.505 , pp. 562-571
    • Bishop, G.A.1    Berbari, N.F.2    Lewis, J.3    Mykytyn, K.4
  • 63
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse
    • Hayashi S, McMahon AP, (2002) Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 244: 305-318.
    • (2002) Dev Biol , vol.244 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 64
    • 18844427353 scopus 로고    scopus 로고
    • Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function
    • Delgehyr N, Sillibourne J, Bornens M, (2005) Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function. J Cell Sci 118: 1565-1575.
    • (2005) J Cell Sci , vol.118 , pp. 1565-1575
    • Delgehyr, N.1    Sillibourne, J.2    Bornens, M.3
  • 65
    • 33846785192 scopus 로고    scopus 로고
    • Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
    • Dawe HR, Farr H, Gull K, (2007) Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells. J Cell Sci 120: 7-15.
    • (2007) J Cell Sci , vol.120 , pp. 7-15
    • Dawe, H.R.1    Farr, H.2    Gull, K.3
  • 66
    • 34250865601 scopus 로고    scopus 로고
    • RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1
    • Pan J, You Y, Huang T, Brody SL, (2007) RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1. J Cell Sci 120: 1868-1876.
    • (2007) J Cell Sci , vol.120 , pp. 1868-1876
    • Pan, J.1    You, Y.2    Huang, T.3    Brody, S.L.4
  • 67
    • 0842301559 scopus 로고    scopus 로고
    • The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila
    • Bellaiche Y, Beaudoin-Massiani O, Stuttem I, Schweisguth F, (2004) The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila. Development 131: 469-478.
    • (2004) Development , vol.131 , pp. 469-478
    • Bellaiche, Y.1    Beaudoin-Massiani, O.2    Stuttem, I.3    Schweisguth, F.4
  • 68
    • 33745649658 scopus 로고    scopus 로고
    • XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation
    • Hyodo-Miura J, Yamamoto TS, Hyodo AC, Iemura S, Kusakabe M, et al. (2006) XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation. Dev Cell 11: 69-79.
    • (2006) Dev Cell , vol.11 , pp. 69-79
    • Hyodo-Miura, J.1    Yamamoto, T.S.2    Hyodo, A.C.3    Iemura, S.4    Kusakabe, M.5
  • 69
    • 37249071974 scopus 로고    scopus 로고
    • Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells
    • Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, et al. (2007) Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol 179: 1133-1140.
    • (2007) J Cell Biol , vol.179 , pp. 1133-1140
    • Sfakianos, J.1    Togawa, A.2    Maday, S.3    Hull, M.4    Pypaert, M.5
  • 70
    • 38849199164 scopus 로고    scopus 로고
    • Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex
    • Costa MR, Wen G, Lepier A, Schroeder T, Gotz M, (2008) Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex. Development 135: 11-22.
    • (2008) Development , vol.135 , pp. 11-22
    • Costa, M.R.1    Wen, G.2    Lepier, A.3    Schroeder, T.4    Gotz, M.5
  • 71
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: paradigms and principles
    • Ingham PW, McMahon AP, (2001) Hedgehog signaling in animal development: paradigms and principles. Genes Dev 15: 3059-3087.
    • (2001) Genes Dev , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 72
    • 0002452569 scopus 로고    scopus 로고
    • Developmental roles and clinical significance of hedgehog signaling
    • McMahon AP, Ingham PW, Tabin CJ, (2003) Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol 53: 1-114.
    • (2003) Curr Top Dev Biol , vol.53 , pp. 1-114
    • McMahon, A.P.1    Ingham, P.W.2    Tabin, C.J.3
  • 73
    • 34547110771 scopus 로고    scopus 로고
    • Patched1 regulates hedgehog signaling at the primary cilium
    • Rohatgi R, Milenkovic L, Scott MP, (2007) Patched1 regulates hedgehog signaling at the primary cilium. Science 317: 372-376.
    • (2007) Science , vol.317 , pp. 372-376
    • Rohatgi, R.1    Milenkovic, L.2    Scott, M.P.3
  • 74
    • 40849142136 scopus 로고    scopus 로고
    • Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery
    • Kiprilov EN, Awan A, Desprat R, Velho M, Clement CA, et al. (2008) Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J Cell Biol 180: 897-904.
    • (2008) J Cell Biol , vol.180 , pp. 897-904
    • Kiprilov, E.N.1    Awan, A.2    Desprat, R.3    Velho, M.4    Clement, C.A.5
  • 75
    • 46449127054 scopus 로고    scopus 로고
    • Beta-arrestin-mediated localization of smoothened to the primary cilium
    • Kovacs JJ, Whalen EJ, Liu R, Xiao K, Kim J, et al. (2008) Beta-arrestin-mediated localization of smoothened to the primary cilium. Science 320: 1777-1781.
    • (2008) Science , vol.320 , pp. 1777-1781
    • Kovacs, J.J.1    Whalen, E.J.2    Liu, R.3    Xiao, K.4    Kim, J.5
  • 76
    • 79952171642 scopus 로고    scopus 로고
    • Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
    • Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT, (2011) Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components. Proc Natl Acad Sci U S A.
    • (2011) Proc Natl Acad Sci U S A
    • Qin, J.1    Lin, Y.2    Norman, R.X.3    Ko, H.W.4    Eggenschwiler, J.T.5
  • 78
    • 73949128987 scopus 로고    scopus 로고
    • The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis
    • Ashique AM, Choe Y, Karlen M, May SR, Phamluong K, et al. (2009) The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal 2: ra70.
    • (2009) Sci Signal , vol.2
    • Ashique, A.M.1    Choe, Y.2    Karlen, M.3    May, S.R.4    Phamluong, K.5
  • 79
    • 34247558062 scopus 로고    scopus 로고
    • The graded response to Sonic Hedgehog depends on cilia architecture
    • Caspary T, Larkins CE, Anderson KV, (2007) The graded response to Sonic Hedgehog depends on cilia architecture. Dev Cell 12: 767-778.
    • (2007) Dev Cell , vol.12 , pp. 767-778
    • Caspary, T.1    Larkins, C.E.2    Anderson, K.V.3
  • 80
    • 78650843442 scopus 로고    scopus 로고
    • Ofd1 is required in limb bud patterning and endochondral bone development
    • Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, et al. (2011) Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol 349: 179-191.
    • (2011) Dev Biol , vol.349 , pp. 179-191
    • Bimonte, S.1    De Angelis, A.2    Quagliata, L.3    Giusti, F.4    Tammaro, R.5
  • 81
    • 70350433799 scopus 로고    scopus 로고
    • Identification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance
    • Blotta S, Tassone P, Prabhala RH, Tagliaferri P, Cervi D, et al. (2009) Identification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance. Blood 114: 3276-3284.
    • (2009) Blood , vol.114 , pp. 3276-3284
    • Blotta, S.1    Tassone, P.2    Prabhala, R.H.3    Tagliaferri, P.4    Cervi, D.5
  • 83
    • 79955783526 scopus 로고    scopus 로고
    • The ciliogenic protein Oral-Facial-Digital 1 regulates the neuronal differentiation of embryonic stem cells
    • Hunkapiller J, Singla V, Seol A, Reiter JF, (2011) The ciliogenic protein Oral-Facial-Digital 1 regulates the neuronal differentiation of embryonic stem cells. Stem Cells Dev 20: 831-841.
    • (2011) Stem Cells Dev , vol.20 , pp. 831-841
    • Hunkapiller, J.1    Singla, V.2    Seol, A.3    Reiter, J.F.4
  • 84
    • 77950591508 scopus 로고    scopus 로고
    • Ofd1, a human disease gene, regulates the length and distal structure of centrioles
    • Singla V, Romaguera-Ros M, Garcia-Verdugo JM, Reiter JF, (2010) Ofd1, a human disease gene, regulates the length and distal structure of centrioles. Dev Cell 18: 410-424.
    • (2010) Dev Cell , vol.18 , pp. 410-424
    • Singla, V.1    Romaguera-Ros, M.2    Garcia-Verdugo, J.M.3    Reiter, J.F.4
  • 85
    • 0034042763 scopus 로고    scopus 로고
    • The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination
    • Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, et al. (2000) The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination. Development 127: 2347-2355.
    • (2000) Development , vol.127 , pp. 2347-2355
    • Murcia, N.S.1    Richards, W.G.2    Yoder, B.K.3    Mucenski, M.L.4    Dunlap, J.R.5
  • 86
    • 34548490748 scopus 로고    scopus 로고
    • Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease
    • Davenport JR, Watts AJ, Roper VC, Croyle MJ, van Groen T, et al. (2007) Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr Biol 17: 1586-1594.
    • (2007) Curr Biol , vol.17 , pp. 1586-1594
    • Davenport, J.R.1    Watts, A.J.2    Roper, V.C.3    Croyle, M.J.4    van Groen, T.5
  • 87
    • 73949094342 scopus 로고    scopus 로고
    • Generation of mice with a conditional allele for Ift172
    • Howard PW, Howard TL, Maurer RA, (2010) Generation of mice with a conditional allele for Ift172. Transgenic Res 19: 121-126.
    • (2010) Transgenic Res , vol.19 , pp. 121-126
    • Howard, P.W.1    Howard, T.L.2    Maurer, R.A.3
  • 88
    • 84862776613 scopus 로고    scopus 로고
    • A role for primary cilia in glutamatergic synaptic integration of adult-born neurons
    • Kumamoto N, Gu Y, Wang J, Janoschka S, Takemaru K, et al. (2012) A role for primary cilia in glutamatergic synaptic integration of adult-born neurons. Nat Neurosci 15: 399-405, S391.
    • (2012) Nat Neurosci , vol.15
    • Kumamoto, N.1    Gu, Y.2    Wang, J.3    Janoschka, S.4    Takemaru, K.5
  • 89
    • 69549122198 scopus 로고    scopus 로고
    • Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
    • Dawe HR, Adams M, Wheway G, Szymanska K, Logan CV, et al. (2009) Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J Cell Sci 122: 2716-2726.
    • (2009) J Cell Sci , vol.122 , pp. 2716-2726
    • Dawe, H.R.1    Adams, M.2    Wheway, G.3    Szymanska, K.4    Logan, C.V.5
  • 90
    • 77951128108 scopus 로고    scopus 로고
    • Functional genomic screen for modulators of ciliogenesis and cilium length
    • Kim J, Lee JE, Heynen-Genel S, Suyama E, Ono K, et al. (2010) Functional genomic screen for modulators of ciliogenesis and cilium length. Nature 464: 1048-1051.
    • (2010) Nature , vol.464 , pp. 1048-1051
    • Kim, J.1    Lee, J.E.2    Heynen-Genel, S.3    Suyama, E.4    Ono, K.5
  • 91
    • 70350494065 scopus 로고    scopus 로고
    • OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilin
    • Coene KL, Roepman R, Doherty D, Afroze B, Kroes HY, et al. (2009) OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilin. Am J Hum Genet 85: 465-481.
    • (2009) Am J Hum Genet , vol.85 , pp. 465-481
    • Coene, K.L.1    Roepman, R.2    Doherty, D.3    Afroze, B.4    Kroes, H.Y.5
  • 92
    • 0031869926 scopus 로고    scopus 로고
    • The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice
    • Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, (1998) The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development 125: 2315-2325.
    • (1998) Development , vol.125 , pp. 2315-2325
    • Grove, E.A.1    Tole, S.2    Limon, J.3    Yip, L.4    Ragsdale, C.W.5
  • 93
    • 0035203948 scopus 로고    scopus 로고
    • The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development
    • Wang DZ, Valdez MR, McAnally J, Richardson J, Olson EN, (2001) The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. Development 128: 4623-4633.
    • (2001) Development , vol.128 , pp. 4623-4633
    • Wang, D.Z.1    Valdez, M.R.2    McAnally, J.3    Richardson, J.4    Olson, E.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.