-
2
-
-
66149143508
-
Quasiexperimental study of the effects of antibiotic use, gastric acid-suppressive agents, and infection control practices on the incidence of Clostridium difficile-associated diarrhea in hospitalized patients
-
Aldeyab M. Harbarth S. Vernaz N. et al. (2009) Quasiexperimental study of the effects of antibiotic use, gastric acid-suppressive agents, and infection control practices on the incidence of Clostridium difficile-associated diarrhea in hospitalized patients. Antimicrob Agents Chemother 53: 2082–2088.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2082-2088
-
-
Aldeyab, M.1
Harbarth, S.2
Vernaz, N.3
-
3
-
-
38549093523
-
Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease
-
Ananthakrishnan A. McGinley E. Binion D. (2008) Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease. Gut 57: 205–210.
-
(2008)
Gut
, vol.57
, pp. 205-210
-
-
Ananthakrishnan, A.1
McGinley, E.2
Binion, D.3
-
5
-
-
1642420279
-
Effect of amoxicillin clavulanate on human fecal flora in a gnotobiotic mouse model measured with group specific 16S r RNA targeted oligonucleotide probes in combination with flow cytometry
-
Barc M. Bourlioux F. Janoir C. Rigothier-Gois L. Boureau H. Doré J. et al. (2004) Effect of amoxicillin clavulanate on human fecal flora in a gnotobiotic mouse model measured with group specific 16S r RNA targeted oligonucleotide probes in combination with flow cytometry. Antimicrob Agents Chemother 48: 1365–1368.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1365-1368
-
-
Barc, M.1
Bourlioux, F.2
Janoir, C.3
Rigothier-Gois, L.4
Boureau, H.5
Doré, J.6
-
6
-
-
0030797218
-
Nuclear factor-κB
-
Barnes P. (1997) Nuclear factor-κB. Int J Biochem 29: 867.
-
(1997)
Int J Biochem
, vol.29
, pp. 867
-
-
Barnes, P.1
-
7
-
-
0033525199
-
C3 toxin activates the stress signaling pathways, JNK and p 38, but antagonizes the activation of AP-1 in rat-1 cells
-
Beltman J. Erickson J. Martin G. Lyons J. Cook S. (1999) C3 toxin activates the stress signaling pathways, JNK and p 38, but antagonizes the activation of AP-1 in rat-1 cells. J Biol Chem 274: 3772–3780.
-
(1999)
J Biol Chem
, vol.274
, pp. 3772-3780
-
-
Beltman, J.1
Erickson, J.2
Martin, G.3
Lyons, J.4
Cook, S.5
-
8
-
-
50249143099
-
Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases
-
Bernstein C. Shanahan F. (2008) Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases. Gut 57: 1185–1191.
-
(2008)
Gut
, vol.57
, pp. 1185-1191
-
-
Bernstein, C.1
Shanahan, F.2
-
9
-
-
0020471183
-
Clostridium difficile in toxic megacolon complicating acute inflammatory bowel disease
-
Bolton R. Read A. (1982) Clostridium difficile in toxic megacolon complicating acute inflammatory bowel disease. Br Med J (Clin Res Ed) 285: 475–476.
-
(1982)
Br Med J (Clin Res Ed
, vol.285
, pp. 475-476
-
-
Bolton, R.1
Read, A.2
-
10
-
-
0021263756
-
Asymptomatic neonatal colonization by Clostridium difficile
-
Bolton R. Tait S. Dear P. (1984) Asymptomatic neonatal colonization by Clostridium difficile. Arch Dis Child 59: 466–472.
-
(1984)
Arch Dis Child
, vol.59
, pp. 466-472
-
-
Bolton, R.1
Tait, S.2
Dear, P.3
-
13
-
-
0029845965
-
A model of host microbial interactions in an open mammalian ecosystem
-
Bry L. Falk P. Midtvedt T. Gordon J. (1996) A model of host microbial interactions in an open mammalian ecosystem. Science 273: 1380–1383.
-
(1996)
Science
, vol.273
, pp. 1380-1383
-
-
Bry, L.1
Falk, P.2
Midtvedt, T.3
Gordon, J.4
-
14
-
-
0018127952
-
Mycobacteria as a possible cause of inflammatory bowel disease
-
Burnham W. Lennard-Jones J. Stanford J. Bird R. (1978) Mycobacteria as a possible cause of inflammatory bowel disease. Lancet 2: 693–696.
-
(1978)
Lancet
, vol.2
, pp. 693-696
-
-
Burnham, W.1
Lennard-Jones, J.2
Stanford, J.3
Bird, R.4
-
15
-
-
41349086881
-
Comparative genomics of clostridia link between the ecological niche and cell surface properties
-
Brüggemann H. Gottschalk G. (2008) Comparative genomics of clostridia link between the ecological niche and cell surface properties. Ann N Y Acad Sci 1125: 73–81.
-
(2008)
Ann N Y Acad Sci
, vol.1125
, pp. 73-81
-
-
Brüggemann, H.1
Gottschalk, G.2
-
16
-
-
33748039462
-
Symbiotic bacteria direct expression of an intestinal bactericidal lectin
-
Cash H. Whitham C. Behrendt C. Hooper L. (2006) Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313: 1126–1130.
-
(2006)
Science
, vol.313
, pp. 1126-1130
-
-
Cash, H.1
Whitham, C.2
Behrendt, C.3
Hooper, L.4
-
17
-
-
39349107697
-
Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea
-
Chang J. Antonopoulos D. Kalra A. Tonelli A. Khalife W. Schmidt T. et al. (2008) Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea. J Infect Dis 197: 435–438.
-
(2008)
J Infect Dis
, vol.197
, pp. 435-438
-
-
Chang, J.1
Antonopoulos, D.2
Kalra, A.3
Tonelli, A.4
Khalife, W.5
Schmidt, T.6
-
20
-
-
33748293143
-
Etiopathogenesis of inflammatory bowel diseases
-
Danese S. Fiocchi C. (2006) Etiopathogenesis of inflammatory bowel diseases. World J Gastroenterol 12: 4807–4812.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 4807-4812
-
-
Danese, S.1
Fiocchi, C.2
-
22
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
Daub H. Weiss F. Wallasch C. Ullrich A. (1996) Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379: 557–560.
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.2
Wallasch, C.3
Ullrich, A.4
-
23
-
-
51349099975
-
Effect of antibiotic therapy on human fecal microbiota and the relation to the development of Clostridium difficile
-
de La Cochetière M. Durand T. Lalande V. Petit J. Potel G. Beaugerie L. 2008. Effect of antibiotic therapy on human fecal microbiota and the relation to the development of Clostridium difficile. Microb Ecol 56:395–402.
-
(2008)
Microb Ecol
, vol.56
, pp. 395-402
-
-
de La Cochetière, M.1
Durand, T.2
Lalande, V.3
Petit, J.4
Potel, G.5
Beaugerie, L.6
-
24
-
-
29144473282
-
Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease
-
Dial S. Delaney J. Barkun A. Suissa S. (2005) Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA 294: 2989–2995.
-
(2005)
JAMA
, vol.294
, pp. 2989-2995
-
-
Dial, S.1
Delaney, J.2
Barkun, A.3
Suissa, S.4
-
25
-
-
33749338125
-
Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy
-
Dial S. Delaney J. Schneider V. Suissa S. (2006) Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy. CMAJ 175: 745–748.
-
(2006)
CMAJ
, vol.175
, pp. 745-748
-
-
Dial, S.1
Delaney, J.2
Schneider, V.3
Suissa, S.4
-
26
-
-
0038466330
-
Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome
-
Dobson G. Hickey C. Trinder J. (2003) Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome. Intensive Care Med 29: 1030.
-
(2003)
Intensive Care Med
, vol.29
, pp. 1030
-
-
Dobson, G.1
Hickey, C.2
Trinder, J.3
-
28
-
-
33845527152
-
Crossfeeding between Bifidobacterium longum BB 536 and acetate-converting, butyrate-producing colon bacteria during growth on oligofructose
-
Falony G. Vlachou A. Verbrugghe K. de Vuyst L. (2006) Crossfeeding between Bifidobacterium longum BB 536 and acetate-converting, butyrate-producing colon bacteria during growth on oligofructose. Appl Environ Microbiol 72: 7835–7841.
-
(2006)
Appl Environ Microbiol
, vol.72
, pp. 7835-7841
-
-
Falony, G.1
Vlachou, A.2
Verbrugghe, K.3
de Vuyst, L.4
-
29
-
-
0035986108
-
Microbial factors in inflammatory bowel disease
-
Farrell R. La Mont J. (2002) Microbial factors in inflammatory bowel disease. Gastroenterol Clin North Am 31: 41–62.
-
(2002)
Gastroenterol Clin North Am
, vol.31
, pp. 41-62
-
-
Farrell, R.1
La Mont, J.2
-
32
-
-
35348857386
-
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
-
Frank D. St Amand A. Feldman R. Boedeker E. Harpaz N. Pace N. (2007) Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 104: 13780–13785.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13780-13785
-
-
Frank, D.1
St Amand, A.2
Feldman, R.3
Boedeker, E.4
Harpaz, N.5
Pace, N.6
-
33
-
-
48049112817
-
Recent developments on the role of Clostridium difficile in inflammatory bowel disease
-
Freeman H. (2008) Recent developments on the role of Clostridium difficile in inflammatory bowel disease. World J Gastroenterol 14: 2794–2796.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 2794-2796
-
-
Freeman, H.1
-
34
-
-
33646381327
-
Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease
-
García Rodríguez L. Ruigómez A. Panés J. (2006) Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease. Gastroenterology 130: 1588–1594.
-
(2006)
Gastroenterology
, vol.130
, pp. 1588-1594
-
-
García Rodríguez, L.1
Ruigómez, A.2
Panés, J.3
-
35
-
-
0022552544
-
The carrier state: Clostridium difficile
-
George R. (1986) The carrier state: Clostridium difficile. Antimicrob Chemother 18(Suppl. A): 47–58.
-
(1986)
Antimicrob Chemother
, vol.18
, Issue.Suppl. A
, pp. 47-58
-
-
George, R.1
-
37
-
-
3042590934
-
The causes of intestinal dysbiosis: a review
-
Hawrelak J. Myers S. (2004) The causes of intestinal dysbiosis: a review. Altern Med Rev 9: 180–197.
-
(2004)
Altern Med Rev
, vol.9
, pp. 180-197
-
-
Hawrelak, J.1
Myers, S.2
-
41
-
-
0023269823
-
Cellular internalisation of Clostridium difficile toxin A
-
Henriques B. Florin I. Thelestam M. (1987) Cellular internalisation of Clostridium difficile toxin A. Microb Pathog 2: 455–463.
-
(1987)
Microb Pathog
, vol.2
, pp. 455-463
-
-
Henriques, B.1
Florin, I.2
Thelestam, M.3
-
42
-
-
23744452926
-
Characterisation of intestinal bacteria in infant stools using real-time PCR and northern hybridisation analyses
-
Hopkins M. Macfarlane G. Furrie E. Fite A. Macfarlane S. (2005) Characterisation of intestinal bacteria in infant stools using real-time PCR and northern hybridisation analyses. FEMS Microbiol Ecol 54: 77–85.
-
(2005)
FEMS Microbiol Ecol
, vol.54
, pp. 77-85
-
-
Hopkins, M.1
Macfarlane, G.2
Furrie, E.3
Fite, A.4
Macfarlane, S.5
-
43
-
-
0036185771
-
Assessment of microbial diversity in human colonic samples by 16S r DNA sequence analysis
-
Hold G. Pryde S. Russell V. Furrie E. Flint H. (2002) Assessment of microbial diversity in human colonic samples by 16S r DNA sequence analysis. FEMS Microbiol Ecol 39: 33–39.
-
(2002)
FEMS Microbiol Ecol
, vol.39
, pp. 33-39
-
-
Hold, G.1
Pryde, S.2
Russell, V.3
Furrie, E.4
Flint, H.5
-
45
-
-
0036399823
-
How host microbial interactions shape the nutrient environment of the mammalian intestine
-
Hooper L. Midwedt T. Gordon J. (2002) How host microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr 22: 283–307.
-
(2002)
Annu Rev Nutr
, vol.22
, pp. 283-307
-
-
Hooper, L.1
Midwedt, T.2
Gordon, J.3
-
48
-
-
0028365510
-
Antibiotic-induced diarrhea and pseudomembranous colitis
-
Jacobs N. Jr. (1994) Antibiotic-induced diarrhea and pseudomembranous colitis. Postgrad Med 95: 111–120.
-
(1994)
Postgrad Med
, vol.95
, pp. 111-120
-
-
Jacobs, N.1
-
49
-
-
33947260554
-
Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function
-
Jank T. Giesemann T. Aktories K. (2007) Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function. Glycobiology 17: 15–22.
-
(2007)
Glycobiology
, vol.17
, pp. 15-22
-
-
Jank, T.1
Giesemann, T.2
Aktories, K.3
-
50
-
-
67349265209
-
National point prevalence of Clostridium difficile in US health care facility inpatients, 2008
-
Jarvis W. Schlosser J. Jarvis A. Chinn R. (2009) National point prevalence of Clostridium difficile in US health care facility inpatients, 2008. Am J Infect Control 37: 263–270.
-
(2009)
Am J Infect Control
, vol.37
, pp. 263-270
-
-
Jarvis, W.1
Schlosser, J.2
Jarvis, A.3
Chinn, R.4
-
51
-
-
0033571379
-
Roles of intracellular calcium and NF-κB in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes
-
Jefferson K. Smith M. Bobak D. Jr (1999) Roles of intracellular calcium and NF-κB in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes. J Immunol 163: 5183–5191.
-
(1999)
J Immunol
, vol.163
, pp. 5183-5191
-
-
Jefferson, K.1
Smith, M.2
Bobak, D.3
-
52
-
-
34248152283
-
Long-term ecological impacts of antibiotic administration on the human intestinal microbiota
-
Jernberg C. Lofmark S. Edlund C. Jansson J. (2007) Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. ISME J 1: 56–66.
-
(2007)
ISME J
, vol.1
, pp. 56-66
-
-
Jernberg, C.1
Lofmark, S.2
Edlund, C.3
Jansson, J.4
-
54
-
-
0020075838
-
Clostridium difficile toxin in acute diarrhoea complicating inflammatory bowel disease
-
Keighley M. Youngs D. Johnson M. Allan R. Burdon D. (1982) Clostridium difficile toxin in acute diarrhoea complicating inflammatory bowel disease. Gut 23: 410–414.
-
(1982)
Gut
, vol.23
, pp. 410-414
-
-
Keighley, M.1
Youngs, D.2
Johnson, M.3
Allan, R.4
Burdon, D.5
-
55
-
-
0031958706
-
Clostridium difficile infection
-
Kelly C. La Mont J. (1998) Clostridium difficile infection. Annu Rev Med 49: 375–390.
-
(1998)
Annu Rev Med
, vol.49
, pp. 375-390
-
-
Kelly, C.1
La Mont, J.2
-
56
-
-
33745536745
-
NF-κB activation pathway is essential for the chemokine expression in intestinal epithelial cells stimulated with Clostridium difficile toxin A
-
Kim J. Lee J. Yoon Y. Ohz Y. Youny J. Kim Y. (2006) NF-κB activation pathway is essential for the chemokine expression in intestinal epithelial cells stimulated with Clostridium difficile toxin A. Scan J Immunol 63: 453–546.
-
(2006)
Scan J Immunol
, vol.63
, pp. 453-546
-
-
Kim, J.1
Lee, J.2
Yoon, Y.3
Ohz, Y.4
Youny, J.5
Kim, Y.6
-
57
-
-
20444395071
-
Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E 2 synthesis in colonocytes via reactive oxygen species and activation of p 38 MAPK
-
Kim H. Rhee S. Kokkotou E. Na X. Savidge T. Moyer M. et al. (2005) Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E 2 synthesis in colonocytes via reactive oxygen species and activation of p 38 MAPK. J Biol Chem 280: 21237–21245.
-
(2005)
J Biol Chem
, vol.280
, pp. 21237-21245
-
-
Kim, H.1
Rhee, S.2
Kokkotou, E.3
Na, X.4
Savidge, T.5
Moyer, M.6
-
58
-
-
0020624897
-
Studies on Clostridium difficile and antimicrobial associated diarrhea or colitis
-
Kobayashi T. (1983) Studies on Clostridium difficile and antimicrobial associated diarrhea or colitis. Jpn J Antibiot 36: 464–476.
-
(1983)
Jpn J Antibiot
, vol.36
, pp. 464-476
-
-
Kobayashi, T.1
-
60
-
-
0022525082
-
Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1–3Gal beta 1–4GlcNAc
-
Krivan H. Clark G. Smith D. Wilkins T. (1986) Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1–3Gal beta 1–4GlcNAc. Infect Immun 53: 573–581.
-
(1986)
Infect Immun
, vol.53
, pp. 573-581
-
-
Krivan, H.1
Clark, G.2
Smith, D.3
Wilkins, T.4
-
61
-
-
33748563622
-
Emergence of Clostridium difficile-associated disease in North America and Europe
-
Kuijper E. Coignard B. Tull P. (2006) Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect 12: 2–18.
-
(2006)
Clin Microbiol Infect
, vol.12
, pp. 2-18
-
-
Kuijper, E.1
Coignard, B.2
Tull, P.3
-
62
-
-
0018892191
-
Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease
-
La Mont J. Trnka Y. (1980) Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease. Lancet 1: 381–383.
-
(1980)
Lancet
, vol.1
, pp. 381-383
-
-
La Mont, J.1
Trnka, Y.2
-
65
-
-
32944466887
-
Ecological and evolutionary forces shaping microbial diversity in the human intestine
-
Ley R. Peterson D. Gordon J. (2006) Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 124: 837–848.
-
(2006)
Cell
, vol.124
, pp. 837-848
-
-
Ley, R.1
Peterson, D.2
Gordon, J.3
-
66
-
-
70350648778
-
The role of infection in inflammatory bowel disease: initiation, exacerbation and protection
-
Lidar M. Langevitz P. Shoenfeld Y. (2009) The role of infection in inflammatory bowel disease: initiation, exacerbation and protection. IMAJ 11: 558–563.
-
(2009)
IMAJ
, vol.11
, pp. 558-563
-
-
Lidar, M.1
Langevitz, P.2
Shoenfeld, Y.3
-
67
-
-
0031408179
-
IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes
-
Linevsky J. Pothoulakis C. Keates S. Warny M. Keates A. Lamont J. et al. (1997) IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes. Am J Physiol 273: 1333–1340.
-
(1997)
Am J Physiol
, vol.273
, pp. 1333-1340
-
-
Linevsky, J.1
Pothoulakis, C.2
Keates, S.3
Warny, M.4
Keates, A.5
Lamont, J.6
-
69
-
-
0029868433
-
Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and apoptosis after cell detachment
-
Mahida Y. Makh S. Hyde S. Gray T. Borriello S. (1996) Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and apoptosis after cell detachment. Gut 38: 337–347.
-
(1996)
Gut
, vol.38
, pp. 337-347
-
-
Mahida, Y.1
Makh, S.2
Hyde, S.3
Gray, T.4
Borriello, S.5
-
70
-
-
78650370258
-
Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridum difficile-associated disease
-
Manges A. Labbe A. Loo V. Atherton J. Behr M. Masson L. et al. (2010) Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridum difficile-associated disease. J Infect Dis 202: 1877–1884.
-
(2010)
J Infect Dis
, vol.202
, pp. 1877-1884
-
-
Manges, A.1
Labbe, A.2
Loo, V.3
Atherton, J.4
Behr, M.5
Masson, L.6
-
71
-
-
30944466824
-
Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
-
Manichanh C. Rigottier-Gois L. Bonnaud E. Gloux K. Pelletier E. Frangeul L. et al. (2006) Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut 55: 205–211.
-
(2006)
Gut
, vol.55
, pp. 205-211
-
-
Manichanh, C.1
Rigottier-Gois, L.2
Bonnaud, E.3
Gloux, K.4
Pelletier, E.5
Frangeul, L.6
-
73
-
-
0036300803
-
Distribution of genes encoding the trypsin-dependent antibiotic ruminococcin A among bacteria isolated from human fecal microbiota
-
Marcille F. Gomez A. Joubert P. Ladiré M. Veau G. Clara A. et al. (2002) Distribution of genes encoding the trypsin-dependent antibiotic ruminococcin A among bacteria isolated from human fecal microbiota. Appl Environ Microbiol 68: 3424–3431.
-
(2002)
Appl Environ Microbiol
, vol.68
, pp. 3424-3431
-
-
Marcille, F.1
Gomez, A.2
Joubert, P.3
Ladiré, M.4
Veau, G.5
Clara, A.6
-
74
-
-
22144490199
-
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
-
Mazmanian S. Liu C. Tzianabos A. Kasper D. (2005) An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 122: 107–118.
-
(2005)
Cell
, vol.122
, pp. 107-118
-
-
Mazmanian, S.1
Liu, C.2
Tzianabos, A.3
Kasper, D.4
-
75
-
-
0032152205
-
Epidemiology, risk factors and treatments for antibiotic-associated diarrhea
-
McFarland L. (1998) Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis 16: 292–307.
-
(1998)
Dig Dis
, vol.16
, pp. 292-307
-
-
McFarland, L.1
-
76
-
-
34247619245
-
Implications of the changing face of Clostridium difficile disease for health care practitioners
-
McFarland L. Beneda H. Clarridge J. Raugi G. (2007) Implications of the changing face of Clostridium difficile disease for health care practitioners. Am J Infect Control 35: 237–253.
-
(2007)
Am J Infect Control
, vol.35
, pp. 237-253
-
-
McFarland, L.1
Beneda, H.2
Clarridge, J.3
Raugi, G.4
-
77
-
-
0019468037
-
Occurrence of Clostridium difficile toxin during the course of inflammatory bowel disease
-
Meyers S. Mayer L. Bottone E. Desmond E. Janowitz H. (1981) Occurrence of Clostridium difficile toxin during the course of inflammatory bowel disease. Gastroenterology 80: 697–770.
-
(1981)
Gastroenterology
, vol.80
, pp. 697-770
-
-
Meyers, S.1
Mayer, L.2
Bottone, E.3
Desmond, E.4
Janowitz, H.5
-
78
-
-
0032557526
-
Multiple signalling pathways lead to the activation of the nuclear factor κB by the Rho family of GT Pases
-
Montaner S. Perona R. Saniger L. Lacal J. (1998) Multiple signalling pathways lead to the activation of the nuclear factor κB by the Rho family of GT Pases. J Biol Chem 273: 12779–12785.
-
(1998)
J Biol Chem
, vol.273
, pp. 12779-12785
-
-
Montaner, S.1
Perona, R.2
Saniger, L.3
Lacal, J.4
-
79
-
-
0025061557
-
C. difficile toxin A increases intestinal permeability and induces Cl– secretion
-
Moore R. Pothoulakis C. La Mont J. Carlson S. Madara J. (1990) C. difficile toxin A increases intestinal permeability and induces Cl– secretion. Am J Physiol 259: G165–G172.
-
(1990)
Am J Physiol
, vol.259
, pp. G165-G172
-
-
Moore, R.1
Pothoulakis, C.2
La Mont, J.3
Carlson, S.4
Madara, J.5
-
80
-
-
77149140102
-
Clostridium difficile infection and inflammatory bowel disease
-
Musa S. Thomson S. Cowan M. Rahman T. (2010) Clostridium difficile infection and inflammatory bowel disease. Scand J Gastroenterol 45: 261–272.
-
(2010)
Scand J Gastroenterol
, vol.45
, pp. 261-272
-
-
Musa, S.1
Thomson, S.2
Cowan, M.3
Rahman, T.4
-
82
-
-
17144406325
-
Clostridium difficile toxin B activates the EGF receptor and the ERK/MAP kinase pathway in human colonocytes
-
Na X. Zhao D. Koon H. Kim H. Husmark J. Moyer M. et al. (2005) Clostridium difficile toxin B activates the EGF receptor and the ERK/MAP kinase pathway in human colonocytes. Gastroenterology 128: 1002–1011.
-
(2005)
Gastroenterology
, vol.128
, pp. 1002-1011
-
-
Na, X.1
Zhao, D.2
Koon, H.3
Kim, H.4
Husmark, J.5
Moyer, M.6
-
83
-
-
0019793682
-
Isolation of Clostridium difficile from the feces and the antibody in sera of young and elderly adults
-
Nakamura S. Mikawa M. Nakashio S. Takabatake M. Okado I. Yamakawa K. et al. (1981) Isolation of Clostridium difficile from the feces and the antibody in sera of young and elderly adults. Microbiol Immunol 25: 345–351.
-
(1981)
Microbiol Immunol
, vol.25
, pp. 345-351
-
-
Nakamura, S.1
Mikawa, M.2
Nakashio, S.3
Takabatake, M.4
Okado, I.5
Yamakawa, K.6
-
84
-
-
0032487573
-
Coordinate activation of activator protein 1 and inflammatory cytokines in response to neisseria gonorrhoeae epithelial cell contact involves stress response kinases
-
Naumann M. Rudel T. Wieland B. Bartsch C. Meyer T. (1998) Coordinate activation of activator protein 1 and inflammatory cytokines in response to neisseria gonorrhoeae epithelial cell contact involves stress response kinases. J Exp Med 188: 1277–1286.
-
(1998)
J Exp Med
, vol.188
, pp. 1277-1286
-
-
Naumann, M.1
Rudel, T.2
Wieland, B.3
Bartsch, C.4
Meyer, T.5
-
85
-
-
70349328455
-
Examination of potential mechanisms to explain the association between proton pump inhibitors and Clostridium difficile infection
-
Nerandzic M. Pultz M. Donskey C. (2009) Examination of potential mechanisms to explain the association between proton pump inhibitors and Clostridium difficile infection. Antimicrob Agents Chemother 53: 4133–4137.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4133-4137
-
-
Nerandzic, M.1
Pultz, M.2
Donskey, C.3
-
86
-
-
58149084782
-
Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents
-
Nomura K. Fujimoto Y. Yamashita M. Morimoto Y. Ohshiro M. Sato K. et al. (2009) Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents. Scand J Gastroenterol 44: 74–78.
-
(2009)
Scand J Gastroenterol
, vol.44
, pp. 74-78
-
-
Nomura, K.1
Fujimoto, Y.2
Yamashita, M.3
Morimoto, Y.4
Ohshiro, M.5
Sato, K.6
-
87
-
-
36549075219
-
Nutrition and colonic health: the critical role of the microbiota
-
O'Keefe S. (2008) Nutrition and colonic health: the critical role of the microbiota. Curr Opin Gastroenterol 24: 51–58.
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 51-58
-
-
O'Keefe, S.1
-
88
-
-
76649099164
-
Tube feeding, the microbiota, and Clostridium difficile infection
-
O'Keefe S. (2010) Tube feeding, the microbiota, and Clostridium difficile infection. World J Gastroenterol 16: 139–142.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 139-142
-
-
O'Keefe, S.1
-
90
-
-
0032520791
-
Role of Rho GT Pase in bradykinin-stimulated nuclear factor-kB activation and IL-1β gene expression in cultured human epithelial cells
-
Pan Z. Ye R. Christiansen S. Jagels M. Bokoch G. Zuraw B. (1998) Role of Rho GT Pase in bradykinin-stimulated nuclear factor-kB activation and IL-1β gene expression in cultured human epithelial cells. J Immunol 160: 3038–3045.
-
(1998)
J Immunol
, vol.160
, pp. 3038-3045
-
-
Pan, Z.1
Ye, R.2
Christiansen, S.3
Jagels, M.4
Bokoch, G.5
Zuraw, B.6
-
91
-
-
34247178951
-
Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile
-
Pechine S. Janoir C. Boureau H. Gleizes A. Tsapis N. Hoys S. et al. (2007) Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile. Vaccine 25: 3946–3954.
-
(2007)
Vaccine
, vol.25
, pp. 3946-3954
-
-
Pechine, S.1
Janoir, C.2
Boureau, H.3
Gleizes, A.4
Tsapis, N.5
Hoys, S.6
-
92
-
-
4444382260
-
Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity
-
Pepin J. Valiquette L. Alary M. Villemure P. Pelletier A. Forget K. et al. (2004) Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. CMAJ 171:466–472.
-
(2004)
CMAJ
, vol.171
, pp. 466-472
-
-
Pepin, J.1
Valiquette, L.2
Alary, M.3
Villemure, P.4
Pelletier, A.5
Forget, K.6
-
93
-
-
0031034469
-
Activation of the nuclear factor-κB by Rho, CDC 42 and Rac-1 proteins
-
Perona R. Montaner S. Saniger L. Sanchez-Perez I. Bravo R. Lacal J. (1997) Activation of the nuclear factor-κB by Rho, CDC 42 and Rac-1 proteins. Genes Dev 11: 463–475.
-
(1997)
Genes Dev
, vol.11
, pp. 463-475
-
-
Perona, R.1
Montaner, S.2
Saniger, L.3
Sanchez-Perez, I.4
Bravo, R.5
Lacal, J.6
-
94
-
-
44649118583
-
Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases
-
Peterson D. Frank D. Pace N. Gordon J. (2008) Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe 3: 417–427.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 417-427
-
-
Peterson, D.1
Frank, D.2
Pace, N.3
Gordon, J.4
-
95
-
-
0034999642
-
Microbes and microbial toxins: paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins
-
Pothoulakis C. La Mont J. (2001) Microbes and microbial toxins: paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins. Am J Physiol Gastrointest Liver Physiol 280: 178–183.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.280
, pp. 178-183
-
-
Pothoulakis, C.1
La Mont, J.2
-
96
-
-
48249135038
-
Clostridium difficile infection and inflammatory bowel disease: a marker for disease extent?
-
Powell N. Jung S. Krishnan B. (2008) Clostridium difficile infection and inflammatory bowel disease: a marker for disease extent? Gut 57: 1183–1184.
-
(2008)
Gut
, vol.57
, pp. 1183-1184
-
-
Powell, N.1
Jung, S.2
Krishnan, B.3
-
98
-
-
34547683600
-
Diversity of the human gastrointestinal tract microbiota revisited
-
Rajilić-Stojanović M. Smidt H. de Vos W. (2007) Diversity of the human gastrointestinal tract microbiota revisited. Environ Microbiol 9: 2125–2136.
-
(2007)
Environ Microbiol
, vol.9
, pp. 2125-2136
-
-
Rajilić-Stojanović, M.1
Smidt, H.2
de Vos, W.3
-
100
-
-
0019504541
-
Bacterial interference between Clostridium difficile and normal fecal flora
-
Rolfe R. Helebian S. Finegold S. (1981) Bacterial interference between Clostridium difficile and normal fecal flora. J Infect Dis 143: 470–475.
-
(1981)
J Infect Dis
, vol.143
, pp. 470-475
-
-
Rolfe, R.1
Helebian, S.2
Finegold, S.3
-
101
-
-
79952350240
-
Clostridium difficile colonization in early infancy is accompanied by changes in intestinal microbiota composition
-
Rousseau C. Levenez F. Fouqueray C. Dore J. Collignon A. Lepage P. (2011) Clostridium difficile colonization in early infancy is accompanied by changes in intestinal microbiota composition. J Clin Microbiol 49: 858–865.
-
(2011)
J Clin Microbiol
, vol.49
, pp. 858-865
-
-
Rousseau, C.1
Levenez, F.2
Fouqueray, C.3
Dore, J.4
Collignon, A.5
Lepage, P.6
-
102
-
-
0017341656
-
Microbial ecology of the gastrointestinal tract
-
Savage D. (1977) Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol 31: 107–133.
-
(1977)
Annu Rev Microbiol
, vol.31
, pp. 107-133
-
-
Savage, D.1
-
104
-
-
3042568878
-
Large clostridial cytotoxins: cellular biology of Rho/Ras-glucosylating toxins
-
Schirmer J. Aktories K. (2004) Large clostridial cytotoxins: cellular biology of Rho/Ras-glucosylating toxins. Biochim Biophys Acta 1673: 66–74.
-
(2004)
Biochim Biophys Acta
, vol.1673
, pp. 66-74
-
-
Schirmer, J.1
Aktories, K.2
-
106
-
-
0033863238
-
Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease
-
Segain J. de la Raingeard B. Bourreille A. Leray V. Gervois N. Rosales C. et al. (2000) Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. Gut 47: 397–403.
-
(2000)
Gut
, vol.47
, pp. 397-403
-
-
Segain, J.1
de la Raingeard, B.2
Bourreille, A.3
Leray, V.4
Gervois, N.5
Rosales, C.6
-
109
-
-
0027982876
-
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
-
Springer T. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301–314.
-
(1994)
Cell
, vol.76
, pp. 301-314
-
-
Springer, T.1
-
110
-
-
0036111857
-
Role of infections in the manifestation or reactivation of inflammatory bowel diseases
-
Stallmach A. Carstens O. (2002) Role of infections in the manifestation or reactivation of inflammatory bowel diseases. Inflamm Bowel Dis 8: 213–218.
-
(2002)
Inflamm Bowel Dis
, vol.8
, pp. 213-218
-
-
Stallmach, A.1
Carstens, O.2
-
111
-
-
24344486498
-
Clostridium difficile associated diarrhoea: diagnosis and treatment
-
Starr J. (2005) Clostridium difficile associated diarrhoea: diagnosis and treatment. BMJ 331: 498–501
-
(2005)
BMJ
, vol.331
, pp. 498-501
-
-
Starr, J.1
-
112
-
-
0035468838
-
Effect of antimicrobial agents on the ecological balance of human microflora
-
Sullivan A. Edlund C. Nord C. (2001) Effect of antimicrobial agents on the ecological balance of human microflora. Lancet Infect Dis 1: 101–114.
-
(2001)
Lancet Infect Dis
, vol.1
, pp. 101-114
-
-
Sullivan, A.1
Edlund, C.2
Nord, C.3
-
113
-
-
77957286175
-
EGF signaling activates proliferation and blocks apoptosis of mouse and human intestinal stem/progenitor cells in long-term monolayer cell culture
-
Suzuki A. Sekiya S. Gunshima E. Fujii S. Taniguchi H. (2010) EGF signaling activates proliferation and blocks apoptosis of mouse and human intestinal stem/progenitor cells in long-term monolayer cell culture. Lab Invest 90:1425–1436
-
(2010)
Lab Invest
, vol.90
, pp. 1425-1436
-
-
Suzuki, A.1
Sekiya, S.2
Gunshima, E.3
Fujii, S.4
Taniguchi, H.5
-
116
-
-
0035189181
-
Role of FliC and FliD flagellar proteins of Clostridium difficile in adherence and gut colonization
-
Tasteyre A. Barc M. Collignon A. Boureau H. Karjalainen T. (2001) Role of FliC and FliD flagellar proteins of Clostridium difficile in adherence and gut colonization. Infect Immun 69: 7937–7940.
-
(2001)
Infect Immun
, vol.69
, pp. 7937-7940
-
-
Tasteyre, A.1
Barc, M.2
Collignon, A.3
Boureau, H.4
Karjalainen, T.5
-
118
-
-
0022471026
-
Isolation of Clostridium difficile from human jejunum: identification of a reservoir for disease?
-
Testore G. Nardi F. Babudieri S. Giuliano M. Di Rosa R. Panichi G. (1986) Isolation of Clostridium difficile from human jejunum: identification of a reservoir for disease? J Clin Pathol 39: 861–862.
-
(1986)
J Clin Pathol
, vol.39
, pp. 861-862
-
-
Testore, G.1
Nardi, F.2
Babudieri, S.3
Giuliano, M.4
Di Rosa, R.5
Panichi, G.6
-
120
-
-
0019484831
-
Association of Clostridium difficile toxin with symptomatic relapse of chronic inflammatory bowel disease
-
Trnka Y. La Mont J. (1981) Association of Clostridium difficile toxin with symptomatic relapse of chronic inflammatory bowel disease. Gastroenterology 80: 693–696.
-
(1981)
Gastroenterology
, vol.80
, pp. 693-696
-
-
Trnka, Y.1
La Mont, J.2
-
121
-
-
33745940132
-
‘Diversion’ colitis caused by Clostridium difficile infection: report of a case
-
Tsironi E. Irving P. Feakins R. Rampton D. (2006) ‘Diversion’ colitis caused by Clostridium difficile infection: report of a case. Dis Colon Rectum 49: 1074–1077.
-
(2006)
Dis Colon Rectum
, vol.49
, pp. 1074-1077
-
-
Tsironi, E.1
Irving, P.2
Feakins, R.3
Rampton, D.4
-
122
-
-
0024384411
-
Intestinal colonization with Clostridium difficile in infants up to 18 months of age
-
Tullus K. Aronsson B. Marcus S. Mollby R. (1989) Intestinal colonization with Clostridium difficile in infants up to 18 months of age. Eur J Clin Microbiol Infect Dis 8: 390–393.
-
(1989)
Eur J Clin Microbiol Infect Dis
, vol.8
, pp. 390-393
-
-
Tullus, K.1
Aronsson, B.2
Marcus, S.3
Mollby, R.4
-
123
-
-
0024312284
-
Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients
-
Tvade M. Rask-Madsen J. (1989) Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients. Lancet 1: 1156–1160.
-
(1989)
Lancet
, vol.1
, pp. 1156-1160
-
-
Tvade, M.1
Rask-Madsen, J.2
-
124
-
-
17444366186
-
Clostridium difficile toxins: mechanism of action and role in disease
-
Voth D. Ballard J. (2005) Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev 18: 247–263.
-
(2005)
Clin Microbiol Rev
, vol.18
, pp. 247-263
-
-
Voth, D.1
Ballard, J.2
-
126
-
-
24944540682
-
Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S r RNA genes
-
Wang M. Ahrne S. Jeppsson B. Molin G. (2005) Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S r RNA genes. FEMS Microbiol Ecol 54: 219–231.
-
(2005)
FEMS Microbiol Ecol
, vol.54
, pp. 219-231
-
-
Wang, M.1
Ahrne, S.2
Jeppsson, B.3
Molin, G.4
-
127
-
-
0034049140
-
p 38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis
-
Warny M. Keates A. Keates S. Castagliuolo I. Zacks J. Aboudola S. et al. (2000) p 38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis. J Clin Invest 105: 1147–1156.
-
(2000)
J Clin Invest
, vol.105
, pp. 1147-1156
-
-
Warny, M.1
Keates, A.2
Keates, S.3
Castagliuolo, I.4
Zacks, J.5
Aboudola, S.6
-
128
-
-
0030911732
-
Activation of transcription factor NF-kB and p 38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
-
Wesselborg S. Bauer M. Vogt M. Schmitz M. Schulze-Osthoff K. (1998) Activation of transcription factor NF-kB and p 38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways. J Biol Chem 272: 12422–12429.
-
(1998)
J Biol Chem
, vol.272
, pp. 12422-12429
-
-
Wesselborg, S.1
Bauer, M.2
Vogt, M.3
Schmitz, M.4
Schulze-Osthoff, K.5
-
129
-
-
0027223050
-
The microecology of Clostridium difficile
-
Wilson K. (1993) The microecology of Clostridium difficile. Clin Infect Dis 16: 214–218.
-
(1993)
Clin Infect Dis
, vol.16
, pp. 214-218
-
-
Wilson, K.1
-
131
-
-
0031684010
-
Temperature gradient gel electrophoresis analysis of 16S r RNA from human fecal samples reveals stable and host-specific communities of active bacteria
-
Zoetendal E. Akkermans A. de Vos W. (1998) Temperature gradient gel electrophoresis analysis of 16S r RNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 64: 3854–3859.
-
(1998)
Appl Environ Microbiol
, vol.64
, pp. 3854-3859
-
-
Zoetendal, E.1
Akkermans, A.2
de Vos, W.3
-
132
-
-
54349126970
-
High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota
-
Zoetendal E. Rajilic-Stojanovic M. de Vos W. (2008) High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut 57: 1605–1615.
-
(2008)
Gut
, vol.57
, pp. 1605-1615
-
-
Zoetendal, E.1
Rajilic-Stojanovic, M.2
de Vos, W.3
|