Synthesis and in vitro biological evaluation of lipophilic cation conjugated photosensitizers for targeting mitochondria

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 2, 2013, Pages 379-387

  Rajaputra, Pallavi ^b   Nkepang, Gregory ^b   Watley, Ryan ^b   You, Youngjae ^a  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Anticancer therapy; Delocalized cationic dye; Mitochondria targeting conjugates; Photodynamic therapy

Indexed keywords

5,10,15 TRIPHENYL 20 (3 BROMOPROPYL PHENYL ETHER) 21,23 DITHIAPORPHYRIN; HYDROCARBON; OXYGEN; PHOSPHONIUM DERIVATIVE; PHOTOSENSITIZING AGENT; PORPHYRIN DI TRIPHENYL PHOSPHONIUM CATION; PORPHYRIN MONO TRIPHENYL PHOSPHONIUM CATION; PORPHYRIN RHODAMINE B CATION; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELLULAR DISTRIBUTION; CONJUGATE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOPHILICITY; MITOCHONDRION; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; PHOTOTOXICITY;

ANIMALS; CATIONS; CELL LINE; CELL SURVIVAL; DRUG EVALUATION, PRECLINICAL; ENERGY TRANSFER; HUMANS; LIGHT; MCF-7 CELLS; MICE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; RHODAMINES; SINGLET OXYGEN;

EID: 84871629685     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.11.032     Document Type: Article

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