메뉴 건너뛰기




Volumn 56, Issue 3, 1996, Pages 544-550

Selective damage to carcinoma mitochondria by the rhodacyanine MKT-077

Author keywords

[No Author keywords available]

Indexed keywords

1 ETHYL 2 [[3 ETHYL 5 (3 METHYL 2 BENZOTHIAZOLINYLIDENE)] 4 OXO 2 THIAZOLIDINYLIDENEMETHYL]PYRIDINIUM CHLORIDE; 1 ETHYL 2 [[3 ETHYL 5 (3 METHYLBENZOTHIAZOLIN 2 YLIDENE) 4 OXOTHIAZOLIDIN 2 YLIDENE]METHYL]PYRIDINIUM CHLORIDE; ANTINEOPLASTIC AGENT; CITRATE SYNTHASE; CYANINE DYE; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

EID: 0030030239     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (131)

References (27)
  • 1
    • 0030064081 scopus 로고    scopus 로고
    • MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation
    • Koya, K., Li, Y., Wang, H., Ukai, T., Tatsuta, N., Kawakami, M., Shishido, T., and Chen L. B. MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation. Cancer Res., 56: 538-543, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 538-543
    • Koya, K.1    Li, Y.2    Wang, H.3    Ukai, T.4    Tatsuta, N.5    Kawakami, M.6    Shishido, T.7    Chen, L.B.8
  • 2
    • 0007574262 scopus 로고
    • Localization of mitochondria in living cells with rhodamine 123
    • Johnson, L. V., Walsh, M. L., and Chen, L. B. Localization of mitochondria in living cells with rhodamine 123 Proc. Natl Acad. Sci USA, 77: 990-994, 1980
    • (1980) Proc. Natl Acad. Sci USA , vol.77 , pp. 990-994
    • Johnson, L.V.1    Walsh, M.L.2    Chen, L.B.3
  • 4
    • 0022492812 scopus 로고
    • Rhodamine 123 as a probe of transmembrane potential in isolated rat liver mitochondria: Spectral and metabolic properties
    • Emaus, R K , Gronwald, R., and Lemasters, J. J. Rhodamine 123 as a probe of transmembrane potential in isolated rat liver mitochondria: spectral and metabolic properties. Biochem Biophys. Acta, 850: 436-448, 1986.
    • (1986) Biochem Biophys. Acta , vol.850 , pp. 436-448
    • Emaus, R.K.1    Gronwald, R.2    Lemasters, J.J.3
  • 5
    • 0019325159 scopus 로고
    • Safranine as membrane potential probe in rat liver mitochondria
    • Zanotti, A., and Azzone, G F. Safranine as membrane potential probe in rat liver mitochondria Arch Biochem. Biophys., 201: 255-265, 1980
    • (1980) Arch Biochem. Biophys. , vol.201 , pp. 255-265
    • Zanotti, A.1    Azzone, G.F.2
  • 6
    • 0016632804 scopus 로고
    • Membrane potentials in mitochondrial preparations as measured by means of a cyanine dye
    • Laris, P. C , Bahr, D P., and Chaffee, R. R. J Membrane potentials in mitochondrial preparations as measured by means of a cyanine dye Biochim Biophys. Acta, 376: 415-425, 1975
    • (1975) Biochim Biophys. Acta , vol.376 , pp. 415-425
    • Laris, P.C.1    Bahr, D.P.2    Chaffee, R.R.J.3
  • 7
    • 0017201717 scopus 로고
    • Safranine as a probe of the mitochondrial membrane potential
    • Akerman, K E. O., and Wikstrom, M. K. F. Safranine as a probe of the mitochondrial membrane potential. FEBS Lett , 68 191-197, 1976
    • (1976) FEBS Lett , vol.68 , pp. 191-197
    • Akerman, K.E.O.1    Wikstrom, M.K.F.2
  • 8
    • 0020561660 scopus 로고
    • Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye
    • Washington DC
    • Bernal, S. D., Lampidis, T. J., McIsaac, R. M., and Chen, L. B. Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye Science (Washington DC), 222: 169-172, 1983.
    • (1983) Science , vol.222 , pp. 169-172
    • Bernal, S.D.1    Lampidis, T.J.2    McIsaac, R.M.3    Chen, L.B.4
  • 9
    • 0022344345 scopus 로고
    • Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells
    • Davis, S , Weiss, M. J., Wong, J. R , Lampidis, T J., and Chen, L. B. Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells. J. Biol Chem., 260: 13844-13850, 1985
    • (1985) J. Biol Chem. , vol.260 , pp. 13844-13850
    • Davis, S.1    Weiss, M.J.2    Wong, J.R.3    Lampidis, T.J.4    Chen, L.B.5
  • 10
    • 0023227833 scopus 로고
    • Basis for the selective cytotoxicity of rhodamine 123
    • Modica-Napolitano, J S , and Aprille, J. R. Basis for the selective cytotoxicity of rhodamine 123. Cancer Res., 47. 4361-4365, 1987
    • (1987) Cancer Res. , vol.47 , pp. 4361-4365
    • Modica-Napolitano, J.S.1    Aprille, J.R.2
  • 11
    • 0023550930 scopus 로고
    • Mechanisms of mitochondrial photosensitization by the cationic dye, N,N′-bis(2-ethyl-1,3-dioxylene)kryptocyanine (EDKC): Preferential inactivation of complex 1 in the electron transport chain
    • Ara, G., Aprille, J R., Malis, C. D., Kane, S. B., Cincotta, L., Foley, J., Bonventre, J V., and Oseroff, A. R. Mechanisms of mitochondrial photosensitization by the cationic dye, N,N′-bis(2-ethyl-1,3-dioxylene)kryptocyanine (EDKC): preferential inactivation of complex 1 in the electron transport chain. Cancer Res., 47: 6580-6585, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 6580-6585
    • Ara, G.1    Aprille, J.R.2    Malis, C.D.3    Kane, S.B.4    Cincotta, L.5    Foley, J.6    Bonventre, J.V.7    Oseroff, A.R.8
  • 12
  • 13
    • 0019748411 scopus 로고
    • Regulation of the mitochondrial adenine nucleotide pool size
    • Aprille, J R., and Austin, J. Regulation of the mitochondrial adenine nucleotide pool size Arch. Biochem. Biophys., 2312. 689-699, 1981.
    • (1981) Arch. Biochem. Biophys. , vol.2312 , pp. 689-699
    • Aprille, J.R.1    Austin, J.2
  • 14
    • 0022183720 scopus 로고
    • Relation of mevalonate synthesis to mitochondrial ubiquinone content and respiratory function in cultured neuroblastoma cells
    • Maltese, W. A., and Aprille, J. R. Relation of mevalonate synthesis to mitochondrial ubiquinone content and respiratory function in cultured neuroblastoma cells J. Biol. Chem., 260: 11524-11529, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 11524-11529
    • Maltese, W.A.1    Aprille, J.R.2
  • 16
    • 0019015732 scopus 로고
    • Postnatal development of rat liver mitochondria: State 3 respiration, adenine nucleotide translocase activity, and the net accumulation of adenine nucleotides
    • Aprille, J R., and Asimakis, G. K. Postnatal development of rat liver mitochondria: state 3 respiration, adenine nucleotide translocase activity, and the net accumulation of adenine nucleotides. Arch. Biochem. Biophys., 201: 564-575, 1980.
    • (1980) Arch. Biochem. Biophys. , vol.201 , pp. 564-575
    • Aprille, J.R.1    Asimakis, G.K.2
  • 17
    • 0016378057 scopus 로고    scopus 로고
    • Determination of the activity of succinate, NADH, choline and glycerophosphate dehydrogenases
    • Singer, T. P. Determination of the activity of succinate, NADH, choline and glycerophosphate dehydrogenases. Methods Biochem. Anal., 22: 123-175.
    • Methods Biochem. Anal. , vol.22 , pp. 123-175
    • Singer, T.P.1
  • 18
    • 0018113648 scopus 로고
    • Preparation and properties of NADH-cytochrome c oxidoreductase (complex I-III)
    • Hatefi, Y., and Stiggal, D. L. Preparation and properties of NADH-cytochrome c oxidoreductase (complex I-III). Methods Enzymol., 53: 5-10, 1978.
    • (1978) Methods Enzymol. , vol.53 , pp. 5-10
    • Hatefi, Y.1    Stiggal, D.L.2
  • 19
    • 2042432480 scopus 로고
    • Cytochrome oxidase from beef heart mitochondria
    • Wharton, D. C., and Tzagoloff, A. Cytochrome oxidase from beef heart mitochondria. Methods Enzymol., 10: 245-250, 1967.
    • (1967) Methods Enzymol. , vol.10 , pp. 245-250
    • Wharton, D.C.1    Tzagoloff, A.2
  • 20
    • 77957010982 scopus 로고
    • Citrate synthase
    • Srere, P A. Citrate synthase. Methods Enzymol , 13: 3-9, 1969.
    • (1969) Methods Enzymol , vol.13 , pp. 3-9
    • Srere, P.A.1
  • 21
    • 0016700864 scopus 로고
    • Detection of specific sequences among DNA fragments separated by electrophoresis
    • Southern, E. M. Detection of specific sequences among DNA fragments separated by electrophoresis. J. Mol. Biol., 98: 503-517, 1975.
    • (1975) J. Mol. Biol. , vol.98 , pp. 503-517
    • Southern, E.M.1
  • 22
    • 0023801422 scopus 로고
    • Selective loss of mitochondrial DNA after treatment of cells with Diter calinium (NSC 335153), an antitumor bis-intercalating agent
    • Segal-Bendirdjian, E., Couland, D., Roques, B. P. and LaPecq, J B. Selective loss of mitochondrial DNA after treatment of cells with Diter calinium (NSC 335153), an antitumor bis-intercalating agent. Cancer Res., 48: 4982-4992, 1988
    • (1988) Cancer Res. , vol.48 , pp. 4982-4992
    • Segal-Bendirdjian, E.1    Couland, D.2    Roques, B.P.3    LaPecq, J.B.4
  • 23
    • 0019306958 scopus 로고
    • Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA
    • Allen, J. A. and Coombs, M. M. Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA. Nature (Lond.), 287: 244-245, 1980
    • (1980) Nature (Lond.) , vol.287 , pp. 244-245
    • Allen, J.A.1    Coombs, M.M.2
  • 24
    • 0019306621 scopus 로고
    • Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxade derivative of benzo(a)pyrene
    • Washington DC
    • Backer, J. M., and Weinstein, I. B. Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxade derivative of benzo(a)pyrene. Science (Washington DC), 209: 297-299, 1980
    • (1980) Science , vol.209 , pp. 297-299
    • Backer, J.M.1    Weinstein, I.B.2
  • 26
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter, C., Park, J-W , and Ames, B. N. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA, 85: 6465-6467, 1988.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.-W.2    Ames, B.N.3
  • 27
    • 0027227593 scopus 로고
    • Gastric and hepatocellular carcinomas do not overexpress the same ribosomal protein messenger RNAs as colonic carcinoma
    • Barnard, G. F., Staniunas, R. J., Mori, M., Puder, M., Jessup, M. J , Steele, G. D., Jr. and Chen, L. B. Gastric and hepatocellular carcinomas do not overexpress the same ribosomal protein messenger RNAs as colonic carcinoma. Cancer Res., 53: 4048-4052, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4048-4052
    • Barnard, G.F.1    Staniunas, R.J.2    Mori, M.3    Puder, M.4    Jessup, M.J.5    Steele Jr., G.D.6    Chen, L.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.