Water soluble, core-modified porphyrins. 3. Synthesis, photophysical properties, and in vitro studies of photosensitization, uptake, and localization with carboxylic acid-substituted derivatives

Journal of Medicinal Chemistry

Volumn 46, Issue 17, 2003, Pages 3734-3747

  You, Youngjae ^a   Gibson, Scott L ^b   Hilf, Russell ^b   Davies, Sherry R ^c   Oseroff, Allan R ^c   Roy, Indrajit ^a   Ohulchanskyy, Tymish Y ^a   Bergey, Earl J ^a   Detty, Michael R ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; CYTOCHROME C OXIDASE; DITHIAPORPHYRIN; DITHIAPORPHYRIN DERIVATIVE; PHOTOFRIN; PORPHYRIN DERIVATIVE; RHODAMINE 123; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CANCER INHIBITION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG SYNTHESIS; DRUG UPTAKE; HUMAN; HUMAN CELL; NONHUMAN; PARTITION COEFFICIENT; PHOTODYNAMICS; PHOTOSENSITIZATION; PHOTOTOXICITY; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBOXYLIC ACIDS; CELL SURVIVAL; CHLOROPHYLL; DARKNESS; DIHEMATOPORPHYRIN ETHER; ELECTRON TRANSPORT COMPLEX IV; FLUORESCENCE; LIGHT; MICE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; RATS; SINGLET OXYGEN; SOLUBILITY; SPECTROPHOTOMETRY; TUMOR CELLS, CULTURED;

EID: 0043234168     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030136i     Document Type: Article

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