Molecular mechanisms of dendrite morphogenesis

Frontiers in Cellular Neuroscience

Volumn , Issue DEC, 2012, Pages

  Arikkath, Jyothi ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Aberrant dendritic morphology; Arborization; Dendrite; Molecular mechanims; Plasticity and learning

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CADHERIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN KINASE IIB; CARRIER PROTEINS AND BINDING PROTEINS; CATENIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN DEPENDENT KINASE 5; CYPIN; CYSTEINE RICH PROTEIN 1; DENSIN 180; EPHRIN; EPHRIN RECEPTOR; ERBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOTCH RECEPTOR; NUCLEAR DBF2 RELATED KINASE; PEPTIDES AND PROTEINS; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN CDC42; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RAC PROTEIN; REELIN; RHO FACTOR; SEMAPHORIN; SERINE THREONINE KINASE 25; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN;

ANAPHASE; CELL ADHESION; CELL CYCLE; CELL FUNCTION; CELL POLARITY; CELL STRUCTURE; CYTOSKELETON; DEGENERATIVE DISEASE; DENDRITE; DENDRITE ARBORIZATION; DISEASE ASSOCIATION; HUMAN; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MORPHOGENESIS; NERVE CELL CHARACTERISTICS AND FUNCTIONS; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PYRAMIDAL NERVE CELL; REVIEW; SYNAPSE; TRANSCRIPTION REGULATION;

EID: 84871532564     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2012.00061     Document Type: Review

References (117)

1. Aizawa, H., Hu, S.C., Bobb, K., Balakrishnan, K., Ince, G., Gurevich, I., Cowan, M., and Ghosh, A. (2004). Dendrite development regulated by CREST, a calcium-regulated transcriptional activator. Science 303, 197-202.
2. Akum, B.F., Chen, M., Gunderson, S.I., Riefler, G.M., Scerri-Hansen, M.M., and Firestein, B.L. (2004). Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly. Nat Neurosci 7, 145-152.
3. Arikkath, J., Israely, I., Tao, Y., Mei, L., Liu, X., and Reichardt, L.F. (2008). Erbin controls dendritic morphogenesis by regulating localization of deltacatenin. J Neurosci 28, 7047-7056.
4. Baj, G., Leone, E., Chao, M.V., and Tongiorgi, E. (2011). Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments. Proc Natl Acad Sci U S A 108, 16813-16818.
5. Barnes, A.P., Lilley, B.N., Pan, Y.A., Plummer, L.J., Powell, A.W., Raines, A.N., Sanes, J.R., and Polleux, F. (2007). LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129, 549-563.
6. Barnes, A.P., and Polleux, F. (2009). Establishment of axon-dendrite polarity in developing neurons. Annu Rev Neurosci 32, 347-381.
7. Bonini, S.A., Ferrari-Toninelli, G., Uberti, D., Montinaro, M., Buizza, L., Lanni, C., Grilli, M., and Memo, M. (2011). Nuclear factor kappaB-dependent neurite remodeling is mediated by Notch pathway. J Neurosci 31, 11697-11705.
8. Bosch, M., and Hayashi, Y. (2012). Structural plasticity of dendritic spines. Curr Opin Neurobiol 22, 383-388.
9. Bourne, J.N., and Harris, K.M. (2008). Balancing structure and function at hippocampal dendritic spines. Annu Rev Neurosci 31, 47-67.
10. Branco, T., Clark, B.A., and Hausser, M. (2010). Dendritic discrimination of temporal input sequences in cortical neurons. Science 329, 1671-1675.
11. Branco, T., and Hausser, M. (2011). Synaptic integration gradients in single cortical pyramidal cell dendrites. Neuron 69, 885-892.
12. Breunig, J.J., Silbereis, J., Vaccarino, F.M., Sestan, N., and Rakic, P. (2007). Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A 104, 20558-20563.
13. Camire, O., Lacaille, J.C., and Topolnik, L. (2012). Dendritic Signaling in Inhibitory Interneurons: Local Tuning via Group I Metabotropic Glutamate Receptors. Front Physiol 3, 259.
14. Casanova, J.R., Nishimura, M., Owens, J.W., and Swann, J.W. (2012). Impact of seizures on developing dendrites: implications for intellectual developmental disabilities. Epilepsia 53 Suppl 1, 116-124.
15. Chao, M.V. (2003). Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci 4, 299-309.
16. Charych, E.I., Akum, B.F., Goldberg, J.S., Jornsten, R.J., Rongo, C., Zheng, J.Q., and Firestein, B.L. (2006). Activity-independent regulation of dendrite patterning by postsynaptic density protein PSD-95. J Neurosci 26, 10164-10176.
17. Chen, C., Wirth, A., and Ponimaskin, E. (2012). Cdc42: an important regulator of neuronal morphology. Int J Biochem Cell Biol 44, 447-451.
18. Chen, H., and Firestein, B.L. (2007). RhoA regulates dendrite branching in hippocampal neurons by decreasing cypin protein levels. J Neurosci 27, 8378-8386.
19. Chen, M., Lucas, K.G., Akum, B.F., Balasingam, G., Stawicki, T.M., Provost, J.M., Riefler, G.M., Jornsten, R.J., and Firestein, B.L. (2005). A novel role for snapin in dendrite patterning: interaction with cypin. Mol Biol Cell 16, 5103-5114.
20. Cheung, Z.H., Chin, W.H., Chen, Y., Ng, Y.P., and Ip, N.Y. (2007). Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons. PLoS Biol 5, e63.
21. Cheung, Z.H., and Ip, N.Y. (2007). The roles of cyclin-dependent kinase 5 in dendrite and synapse development. Biotechnol J 2, 949-957.
22. Couch, B.A., Demarco, G.J., Gourley, S.L., and Koleske, A.J. (2010). Increased dendrite branching in AbetaPP/PS1 mice and elongation of dendrite arbors by fasudil administration. Journal of Alzheimer's disease: JAD 20, 1003-1008.
23. Cox, T.M., and Cachon-Gonzalez, M.B. (2012). The cellular pathology of lysosomal diseases. J Pathol 226, 241-254.
24. Cubelos, B., Sebastian-Serrano, A., Beccari, L., Calcagnotto, M.E., Cisneros, E., Kim, S., Dopazo, A., Alvarez-Dolado, M., Redondo, J.M., Bovolenta, P., Walsh, C.A., and Nieto, M. (2010). Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron 66, 523-535.
25. Cui-Wang, T., Hanus, C., Cui, T., Helton, T., Bourne, J., Watson, D., Harris, K.M., and Ehlers, M.D. (2012). Local zones of endoplasmic reticulum complexity confine cargo in neuronal dendrites. Cell 148, 309-321.
26. D'arcangelo, G. (2006). Reelin mouse mutants as models of cortical development disorders. Epilepsy Behav 8, 81-90.
27. de Anda, F.C., Pollarolo, G., da Silva, J.S., Camoletto, P.G., Feiguin, F., and Dotti, C.G. (2005). Centrosome localization determines neuronal polarity. Nature 436, 704-708.
28. de Curtis, I. (2008). Functions of Rac GTPases during neuronal development. Dev Neurosci 30, 47-58.
29. De Jong, A.P., Schmitz, S.K., Toonen, R.F., and Verhage, M. (2012). Dendritic position is a major determinant of presynaptic strength. J Cell Biol 197, 327-337.
30. De La Torre-Ubieta, L., and Bonni, A. (2011). Transcriptional regulation of neuronal polarity and morphogenesis in the mammalian brain. Neuron 72, 22-40.
31. Ehlinger, D.G., Bergstrom, H.C., Mcdonald, C.G., and Smith, R.F. (2012). Nicotine-induced dendritic remodeling in the insular cortex. Neurosci Lett 516, 89-93.
32. Elia, L.P., Yamamoto, M., Zang, K., and Reichardt, L.F. (2006). P120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins. Neuron 51, 43-56.
33. Elston, G.N. (2003). Cortex, cognition and the cell: new insights into the pyramidal neuron and prefrontal function. Cerebral Cortex 13, 1124-1138.
34. Emoto, K. (2012). Signaling mechanisms that coordinate the development and maintenance of dendritic fields. Curr Opin Neurobiol 22, 805-811.
35. Firestein, B.L., Brenman, J.E., Aoki, C., Sanchez-Perez, A.M., El-Husseini, A.E., and Bredt, D.S. (1999). Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting. Neuron 24, 659-672.
36. Fu, W.Y., Cheng, K., Fu, A.K., and Ip, N.Y. (2011). Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development. Neuroscience 180, 353-359.
37. Goldberg, J.H., and Yuste, R. (2005). Space matters: local and global dendritic Ca2+ compartmentalization in cortical interneurons. Trends Neurosci 28, 158-167.
38. Gonzalez-Billault, C., Del Rio, J.A., Urena, J.M., Jimenez-Mateos, E.M., Barallobre, M.J., Pascual, M., Pujadas, L., Simo, S., Torre, A.L., Gavin, R., Wandosell, F., Soriano, E., and Avila, J. (2005). A role of MAP1B in Reelin-dependent neuronal migration. Cereb Cortex 15, 1134-1145.
39. Govindarajan, A., Israely, I., Huang, S.Y., and Tonegawa, S. (2011). The dendritic branch is the preferred integrative unit for protein synthesisdependent LTP. Neuron 69, 132-146.
40. Gutierrez, H., and Davies, A.M. (2011). Regulation of neural process growth, elaboration and structural plasticity by NF-kappaB. Trends Neurosci 34, 316-325.
41. Gutierrez, H., Hale, V.A., Dolcet, X., and Davies, A. (2005). NF-kappaB signaling regulates the growth of neural processes in the developing PNS and CNS. Development 132, 1713-1726.
42. Hand, R., Bortone, D., Mattar, P., Nguyen, L., Heng, J.I., Guerrier, S., Boutt, E., Peters, E., Barnes, A.P., Parras, C., Schuurmans, C., Guillemot, F., and Polleux, F. (2005). Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex. Neuron 48, 45-62.
43. Harnett, M.T., Makara, J.K., Spruston, N., Kath, W.L., and Magee, J.C. (2012). Synaptic amplification by dendritic spines enhances input cooperativity. Nature 491, 599-602.
44. Hernandez-Deviez, D.J., Casanova, J.E., and Wilson, J.M. (2002). Regulation of dendritic development by the ARF exchange factor ARNO. Nat Neurosci 5, 623-624.
45. Hoogenraad, C.C., Milstein, A.D., Ethell, I.M., Henkemeyer, M., and Sheng, M. (2005). GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nat Neurosci 8, 906-915.
46. Horch, H.W., and Katz, L.C. (2002). BDNF release from single cells elicits local dendritic growth in nearby neurons. Nat Neurosci 5, 1177-1184.
47. Huang, Z., Zang, K., and Reichardt, L.F. (2005). The origin recognition core complex regulates dendrite and spine development in postmitotic neurons. J Cell Biol 170, 527-535.
48. Jan, Y.N., and Jan, L.Y. (2010). Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci 11, 316-328.
49. Kasugai, Y., Swinny, J.D., Roberts, J.D., Dalezios, Y., Fukazawa, Y., Sieghart, W., Shigemoto, R., and Somogyi, P. (2010). Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. Eur J Neurosci 32, 1868-1888.
50. Kim, A.H., Puram, S.V., Bilimoria, P.M., Ikeuchi, Y., Keough, S., Wong, M., Rowitch, D., and Bonni, A. (2009). A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell 136, 322-336.
51. Kim, E., and Sheng, M. (2004). PDZ domain proteins of synapses. Nat Rev Neurosci 5, 771-781.
52. Kim, S., Guzman, S.J., Hu, H., and Jonas, P. (2012). Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons. Nat Neurosci 15, 600-606.
53. Klein, R. (2009). Bidirectional modulation of synaptic functions by Eph/ephrin signaling. Nat Neurosci 12, 15-20.
54. Kolk, S.M., Gunput, R.A., Tran, T.S., Van Den Heuvel, D.M., Prasad, A.A., Hellemons, A.J., Adolfs, Y., Ginty, D.D., Kolodkin, A.L., Burbach, J.P., Smidt, M.P., and Pasterkamp, R.J. (2009). Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting. J Neurosci 29, 12542-12557.
55. Kolomeets, N.S., Orlovskaya, D.D., and Uranova, N.A. (2007). Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia. Synapse 61, 615-621.
56. Kulkarni, V.A., and Firestein, B.L. (2012). The dendritic tree and brain disorders. Mol Cell Neurosci 50, 10-20.
57. Kwon, M., Fernandez, J.R., Zegarek, G.F., Lo, S.B., and Firestein, B.L. (2011). BDNF-promoted increases in proximal dendrites occur via CREBdependent transcriptional regulation of cypin. J Neurosci 31, 9735-9745.
58. Lai, C.S., Franke, T.F., and Gan, W.B. (2012). Opposite effects of fear conditioning and extinction on dendritic spine remodelling. Nature 483, 87-91.
59. Lambert De Rouvroit, C., and Goffinet, A.M. (2001). Neuronal migration. Mech Dev 105, 47-56.
60. Larkum, M.E., Nevian, T., Sandler, M., Polsky, A., and Schiller, J. (2009). Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle. Science 325, 756-760.
61. Leemhuis, J., Boutillier, S., Barth, H., Feuerstein, T.J., Brock, C., Nurnberg, B., Aktories, K., and Meyer, D.K. (2004). Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites. J Biol Chem 279, 585-596.
62. Li, N., Zhao, C.T., Wang, Y., and Yuan, X.B. (2010). The transcription factor Cux1 regulates dendritic morphology of cortical pyramidal neurons. PLoS One 5, e10596.
63. Liston, C., Miller, M.M., Goldwater, D.S., Radley, J.J., Rocher, A.B., Hof, P.R., Morrison, J.H., and Mcewen, B.S. (2006). Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J Neurosci 26, 7870-7874.
64. Litterman, N., Ikeuchi, Y., Gallardo, G., O'connell, B.C., Sowa, M.E., Gygi, S.P., Harper, J.W., and Bonni, A. (2011). An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. PLoS Biol 9, e1001060.
65. Liu, W.S., Pesold, C., Rodriguez, M.A., Carboni, G., Auta, J., Lacor, P., Larson, J., Condie, B.G., Guidotti, A., and Costa, E. (2001). Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse. Proc Natl Acad Sci U S A 98, 3477-3482.
66. Lu, R., Liu, X., Long, H., and Ma, L. (2012). Effects of prenatal cocaine and heroin exposure on neuronal dendrite morphogenesis and spatial recognition memory in mice. Neurosci Lett 522, 128-133.
67. Lujan, R., Maylie, J., and Adelman, J.P. (2009). New sites of action for GIRK and SK channels. Nat Rev Neurosci 10, 475-480.
68. Luo, L. (2002). Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu Rev Cell Dev Biol 18, 601-635.
69. Ma, L., Greenwood, J.A., and Schachner, M. (2011). CRP1, a protein localized in filopodia of growth cones, is involved in dendritic growth. J Neurosci 31, 16781-16791.
70. Marin, O., Valiente, M., Ge, X., and Tsai, L.H. (2010). Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol 2, a001834.
71. Matsuki, T., Matthews, R.T., Cooper, J.A., Van Der Brug, M.P., Cookson, M.R., Hardy, J.A., Olson, E.C., and Howell, B.W. (2010). Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment. Cell 143, 826-836.
72. Matsuo, N., Reijmers, L., and Mayford, M. (2008). Spine-type-specific recruitment of newly synthesized AMPA receptors with learning. Science 319, 1104-1107.
73. Matus, A. (2000). Actin-based plasticity in dendritic spines. Science 290, 754-758.
74. Mcallister, A.K. (2000). Cellular and molecular mechanisms of dendrite growth. Cereb Cortex 10, 963-973.
75. Mcallister, A.K., Lo, D.C., and Katz, L.C. (1995). Neurotrophins regulate dendritic growth in developing visual cortex. Neuron 15, 791-803.
76. Mendez, P., and Bacci, A. (2011). Assortment of GABAergic plasticity in the cortical interneuron melting pot. Neural Plast 2011, 976856.
77. Metz, A.E., Yau, H.J., Centeno, M.V., Apkarian, A.V., and Martina, M. (2009). Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain. Proc Natl Acad Sci U S A 106, 2423-2428.
78. Murakoshi, H., and Yasuda, R. (2012). Postsynaptic signaling during plasticity of dendritic spines. Trends Neurosci 35, 135-143.
79. Nadif Kasri, N., and Van Aelst, L. (2008). Rho-linked genes and neurological disorders. Pflugers Arch 455, 787-797.
80. Nakamura, F., Ugajin, K., Yamashita, N., Okada, T., Uchida, Y., Taniguchi, M., Ohshima, T., and Goshima, Y. (2009). Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice. J Comp Neurol 516, 360-375.
81. Niisato, E., Nagai, J., Yamashita, N., Abe, T., Kiyonari, H., Goshima, Y., and Ohshima, T. (2012). CRMP4 suppresses apical dendrite bifurcation of CA1 pyramidal neurons in the mouse hippocampus. Dev Neurobiol 72, 1447-1457.
82. Niu, S., Renfro, A., Quattrocchi, C.C., Sheldon, M., and D'arcangelo, G. (2004). Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway. Neuron 41, 71-84.
83. Okabe, S. (2012). Molecular dynamics of the excitatory synapse. Adv Exp Med Biol 970, 131-152.
84. Papouin, T., Ladepeche, L., Ruel, J., Sacchi, S., Labasque, M., Hanini, M., Groc, L., Pollegioni, L., Mothet, J.P., and Oliet, S.H. (2012). Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists. Cell 150, 633-646.
85. Pavlowsky, A., Chelly, J., and Billuart, P. (2012). Emerging major synaptic signaling pathways involved in intellectual disability. Mol Psychiatry 17, 682-693.
86. Penzes, P., Cahill, M.E., Jones, K.A., Vanleeuwen, J.E., and Woolfrey, K.M. (2011). Dendritic spine pathology in neuropsychiatric disorders. Nat Neurosci 14, 285-293.
87. Petralia, R.S., Wang, Y.X., Hua, F., Yi, Z., Zhou, A., Ge, L., Stephenson, F.A., and Wenthold, R.J. (2010). Organization of NMDA receptors at extrasynaptic locations. Neuroscience 167, 68-87.
88. Puram, S.V., Kim, A.H., Ikeuchi, Y., Wilson-Grady, J.T., Merdes, A., Gygi, S.P., and Bonni, A. (2011). A CaMKIIbeta signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat Neurosci 14, 973-983.
89. Quitsch, A., Berhorster, K., Liew, C.W., Richter, D., and Kreienkamp, H.J. (2005). Postsynaptic shank antagonizes dendrite branching induced by the leucine-rich repeat protein Densin-180. J Neurosci 25, 479-487.
90. Radley, J.J., Rocher, A.B., Janssen, W.G., Hof, P.R., Mcewen, B.S., and Morrison, J.H. (2005). Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp Neurol 196, 199-203.
91. Ratnayaka, A., Marra, V., Branco, T., and Staras, K. (2011). Extrasynaptic vesicle recycling in mature hippocampal neurons. Nat Commun 2, 531.
92. Redmond, L., Kashani, A.H., and Ghosh, A. (2002). Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 34, 999-1010.
93. Rosso, S.B., Sussman, D., Wynshaw-Boris, A., and Salinas, P.C. (2005). Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat Neurosci 8, 34-42.
94. Salinas, P.C., and Zou, Y. (2008). Wnt signaling in neural circuit assembly. Annu Rev Neurosci 31, 339-358.
95. Sanders, J., Cowansage, K., Baumgartel, K., and Mayford, M. (2012). Elimination of dendritic spines with long-term memory is specific to active circuits. J Neurosci 32, 12570-12578.
96. Segal, R.A. (2003). Selectivity in neurotrophin signaling: theme and variations. Annu Rev Neurosci 26, 299-330.
97. Shelly, M., Cancedda, L., Lim, B.K., Popescu, A.T., Cheng, P.L., Gao, H., and Poo, M.M. (2011). Semaphorin3A regulates neuronal polarization by suppressing axon formation and promoting dendrite growth. Neuron 71, 433-446.
98. Siegel, D.A., Huang, M.K., and Becker, S.F. (2002). Ectopic dendrite initiation: CNS pathogenesis as a model of CNS development. Int J Dev Neurosci 20, 373-389.
99. Spruston, N. (2008). Pyramidal neurons: dendritic structure and synaptic integration. Nat Rev Neurosci 9, 206-221.
100. Su, S.C., and Tsai, L.H. (2011). Cyclin-dependent kinases in brain development and disease. Annu Rev Cell Dev Biol 27, 465-491.
101. Sweet, E.S., Previtera, M.L., Fernandez, J.R., Charych, E.I., Tseng, C.Y., Kwon, M., Starovoytov, V., Zheng, J.Q., and Firestein, B.L. (2011). PSD-95 alters microtubule dynamics via an association with EB3. J Neurosci 31, 1038-1047.
102. Tan, Z.J., Peng, Y., Song, H.L., Zheng, J.J., and Yu, X. (2010). N-cadherin dependent neuron-neuron interaction is required for the maintenance of activity-induced dendrite growth. Proc Natl Acad Sci U S A 107, 9873-9878.
103. Terabayashi, T., Itoh, T.J., Yamaguchi, H., Yoshimura, Y., Funato, Y., Ohno, S., and Miki, H. (2007). Polarity-regulating kinase partitioning-defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons. J Neurosci 27, 13098-13107.
104. Tran, T.S., Rubio, M.E., Clem, R.L., Johnson, D., Case, L., Tessier-Lavigne, M., Huganir, R.L., Ginty, D.D., and Kolodkin, A.L. (2009). Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS. Nature 462, 1065-1069.
105. Tye, K.M., and Deisseroth, K. (2012). Optogenetic investigation of neural circuits underlying brain disease in animal models. Nat Rev Neurosci 13, 251-266.
106. Ultanir, S.K., Hertz, N.T., Li, G., Ge, W.P., Burlingame, A.L., Pleasure, S.J., Shokat, K.M., Jan, L.Y., and Jan, Y.N. (2012). Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron 73, 1127-1142.
107. Vanleeuwen, J.E., and Penzes, P. (2012). Long-term perturbation of spine plasticity results in distinct impairments of cognitive function. J Neurochem 123, 781-789.
108. Verpelli, C., and Sala, C. (2012). Molecular and synaptic defects in intellectual disability syndromes. Curr Opin Neurobiol 22, 530-536.
109. Vodrazka, P., Korostylev, A., Hirschberg, A., Swiercz, J.M., Worzfeld, T., Deng, S., Fazzari, P., Tamagnone, L., Offermanns, S., and Kuner, R. (2009). The semaphorin 4D-plexin-B signalling complex regulates dendritic and axonal complexity in developing neurons via diverse pathways. Eur J Neurosci 30, 1193-1208.
110. Wayman, G.A., Impey, S., Marks, D., Saneyoshi, T., Grant, W.F., Derkach, V., and Soderling, T.R. (2006). Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2. Neuron 50, 897-909.
111. Weimer, R.M., Hill, T.C., Hamilton, A.M., and Zito, K. (2012). Imaging synaptic protein dynamics using photoactivatable green fluorescent protein. Cold Spring Harb Protoc 2012, 771-777.
112. Wu, G.Y., Zou, D.J., Rajan, I., and Cline, H. (1999). Dendritic dynamics in vivo change during neuronal maturation. J Neurosci 19, 4472-4483.
113. Wu, J.I., Lessard, J., Olave, I.A., Qiu, Z., Ghosh, A., Graef, I.A., and Crabtree, G.R. (2007). Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 56, 94-108.
114. Yacoubian, T.A., and Lo, D.C. (2000). Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth. Nat Neurosci 3, 342-349.
115. Ye, B., Zhang, Y., Song, W., Younger, S.H., Jan, L.Y., and Jan, Y.N. (2007). Growing dendrites and axons differ in their reliance on the secretory pathway. Cell 130, 717-729.
116. Yu, W., and Lu, B. (2012). Synapses and dendritic spines as pathogenic targets in Alzheimer's disease. Neural Plast 2012, 247150.
117. Zhang, P., Yu, P.C., Tsang, A.H., Chen, Y., Fu, A.K., Fu, W.Y., Chung, K.K., and Ip, N.Y. (2010). S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development. J Neurosci 30, 14366-14370.