Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development

Neuroscience

Volumn 180, Issue , 2011, Pages 353-359

  Fu, W Y ^a   Cheng, K ^a   Fu, A K Y ^a   Ip, N Y ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Cyclin dependent kinase 5; Dendrite; Neurite; Neuronal development; P35

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE PCTAIRE1; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DENDRITE; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GROWTH CONE; HIPPOCAMPUS; HUMAN; HUMAN CELL; MOUSE; NERVE CELL DIFFERENTIATION; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

EID: 79953179658     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.02.024     Document Type: Article

References (21)

1. Besset V., Rhee K., Wolgemuth D.J. The cellular distribution and kinase activity of the Cdk family member Pctaire1 in the adult mouse brain and testis suggest functions in differentiation. Cell Growth Differ 1999, 10:173-181.
2. Cheng K., Li Z., Fu W.Y., Wang J.H., Fu A.K., Ip N.Y. Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35. J Biol Chem 2002, 277:31988-31993.
3. Cole A.R. PCTK proteins: the forgotten brain kinases?. Neurosignals 2009, 17:288-297.
4. Fu W.Y., Chen Y., Sahin M., Zhao X.S., Shi L., Bikoff J.B., Lai K.O., Yung W.H., Fu A.K., Greenberg M.E., Ip N.Y. Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism. Nat Neurosci 2007, 10:67-76.
5. Graeser R., Gannon J., Poon R.Y., Dubois T., Aitken A., Hunt T. Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in neuro-2A cells. J Cell Sci 2002, 115:3479-3490.
6. Hirose T., Tamaru T., Okumura N., Nagai K., Okada M. PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons. Eur J Biochem 1997, 249:481-488.
7. Jaworski J., Spangler S., Seeburg D.P., Hoogenraad C.C., Sheng M. Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway. J Neurosci 2005, 25:11300-11312.
8. Kajiwara Y., Buxbaum J.D., Grice D.E. SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner. Biol Psychiatry 2009, 66:918-925.
9. Kumar V., Zhang M.X., Swank M.W., Kunz J., Wu G.Y. Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways. J Neurosci 2005, 25:11288-11299.
10. Liu Y., Cheng K., Gong K., Fu A.K., Ip N.Y. Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis. J Biol Chem 2006, 281:9852-9858.
11. Meyerson M., Enders G.H., Wu C.L., Su L.K., Gorka C., Nelson C., Harlow E., Tsai L.H. A family of human cdc2-related protein kinases. EMBO J 1992, 11:2909-2917.
12. Mokalled M.H., Johnson A., Kim Y., Oh J., Olson E.N. Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development. Development 2010, 137:2365-2374.
13. Ohshima T., Hirasawa M., Tabata H., Mutoh T., Adachi T., Suzuki H., Saruta K., Iwasato T., Itohara S., Hashimoto M., Nakajima K., Ogawa M., Kulkarni A.B., Mikoshiba K. Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development 2007, 134:2273-2282.
14. Okuda T., Cleveland J.L., Downing J.R. PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene 1992, 7:2249-2258.
15. Ou C.Y., Poon V.Y., Maeder C.I., Watanabe S., Lehrman E.K., Fu A.K., Park M., Fu W.Y., Jorgensen E.M., Ip N.Y., Shen K. Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components. Cell 2010, 141:846-858.
16. Palmer K.J., Konkel J.E., Stephens D.J. PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport. J Cell Sci 2005, 118:3839-3847.
17. Sala C., Piech V., Wilson N.R., Passafaro M., Liu G., Sheng M. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 2001, 31:115.
18. Sladeczek F., Camonis J.H., Burnol A.F., Le Bouffant F. The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins. Mol Gen Genet 1997, 254:571-577.
19. Yamochi T., Nishimoto I., Okuda T., Matsuoka M. ik3-1/Cables is associated with Trap and Pctaire2. Biochem Biophys Res Commun 2001, 286:1045-1050.
20. Zhang P., Yu P.C., Tsang A.H., Chen Y., Fu A.K., Fu W.Y., Chung K.K., Ip N.Y. S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development. J Neurosci 2010, 30:14366-14370.
21. Zukerberg L.R., Patrick G.N., Nikolic M., Humbert S., Wu C.L., Lanier L.M., Gertler F.B., Vidal M., Van Etten R.A., Tsai L.H. Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron 2000, 26:633-646.