Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: A new unifying principle

Science

Volumn 325, Issue 5941, 2009, Pages 756-760

  Larkum, Matthew E ^a   Nevian, Thomas ^a   Sandier, Maya ^b   Polsky, Alon ^b   Schiller, Jackie ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID;

MEASUREMENT METHOD; NERVOUS SYSTEM;

ARTICLE; BRAIN DEPTH STIMULATION; CALCIUM TRANSPORT; COMPUTER SIMULATION; DENDRITE; HUMAN; INTEGRATION; NERVE CELL; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; AXONS; CALCIUM SIGNALING; COMPUTER SIMULATION; DENDRITES; EXCITATORY POSTSYNAPTIC POTENTIALS; MODELS, NEUROLOGICAL; N-METHYLASPARTATE; NEOCORTEX; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM; SYNAPSES; SYNAPTIC POTENTIALS;

EID: 68449085134     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1171958     Document Type: Article

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35. We thank B. Sakmann for generous support and comments on the manuscript and Y. Schiller for helpful comments and discussions on the manuscript. We thank K. Fischer for Neurolucida reconstructions of the biocytin-filled neurons. This study was supported by NIH, the Israel Science Foundation, and the Rappaport Foundation (J.S.); by the Swiss National Science Foundation (M.L., grant PP0033-119159; T.N., grant 3100A0-118395); and by SystemsX.ch (M.I., Neurochoice). The authors declare that they have no competing financial interests.