-
1
-
-
78649516124
-
Functions of T cells in asthma: more than just T(H)2 cells
-
Lloyd CM, Hessel EM, (2010) Functions of T cells in asthma: more than just T(H)2 cells. Nat Rev Immunol 10: 838-848.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 838-848
-
-
Lloyd, C.M.1
Hessel, E.M.2
-
2
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, et al. (1998) Requirement for IL-13 independently of IL-4 in experimental asthma. Science 282: 2261-2263.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grunig, G.1
Warnock, M.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
-
3
-
-
0041629644
-
Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma
-
Corry DB, Kheradmand F, (2002) Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma. Am J Respir Med 1: 185-193.
-
(2002)
Am J Respir Med
, vol.1
, pp. 185-193
-
-
Corry, D.B.1
Kheradmand, F.2
-
5
-
-
77956955243
-
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
-
Lajoie S, Lewkowich IP, Suzuki Y, Clark JR, Sproles AA, et al. (2010) Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat Immunol 11: 928-935.
-
(2010)
Nat Immunol
, vol.11
, pp. 928-935
-
-
Lajoie, S.1
Lewkowich, I.P.2
Suzuki, Y.3
Clark, J.R.4
Sproles, A.A.5
-
6
-
-
78649850406
-
IL-17 and IL-22 in atopic allergic disease
-
Souwer Y, Szegedi K, Kapsenberg ML, de Jong EC, (2010) IL-17 and IL-22 in atopic allergic disease. Curr Opin Immunol 22: 821-826.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 821-826
-
-
Souwer, Y.1
Szegedi, K.2
Kapsenberg, M.L.3
de Jong, E.C.4
-
7
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, et al. (2006) The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
-
8
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, et al. (2008) T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 28: 29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
-
9
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, et al. (2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
-
10
-
-
61949463911
-
IL-17 and Th17 Cells
-
Korn T, Bettelli E, Oukka M, Kuchroo VK, (2009) IL-17 and Th17 Cells. Annu Rev Immunol 27: 485-517.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
11
-
-
60749107176
-
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
-
McGeachy MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, et al. (2009) The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol 10: 314-324.
-
(2009)
Nat Immunol
, vol.10
, pp. 314-324
-
-
McGeachy, M.J.1
Chen, Y.2
Tato, C.M.3
Laurence, A.4
Joyce-Shaikh, B.5
-
12
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, et al. (2009) Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30: 576-587.
-
(2009)
Immunity
, vol.30
, pp. 576-587
-
-
Chung, Y.1
Chang, S.H.2
Martinez, G.J.3
Yang, X.O.4
Nurieva, R.5
-
13
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, et al. (2007) Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 8: 950-957.
-
(2007)
Nat Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
-
14
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, et al. (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201: 233-240.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
-
15
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, et al. (2007) Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med 204: 2803-2812.
-
(2007)
J Exp Med
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
Maeda, S.4
Teradaira, S.5
-
16
-
-
0034833339
-
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
-
Molet S, Hamid Q, Davoine F, Nutku E, Taha R, et al. (2001) IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 108: 430-438.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 430-438
-
-
Molet, S.1
Hamid, Q.2
Davoine, F.3
Nutku, E.4
Taha, R.5
-
17
-
-
33846889522
-
A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
-
Krueger GG, Langley RG, Leonardi C, Yeilding N, Guzzo C, et al. (2007) A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N Engl J Med 356: 580-592.
-
(2007)
N Engl J Med
, vol.356
, pp. 580-592
-
-
Krueger, G.G.1
Langley, R.G.2
Leonardi, C.3
Yeilding, N.4
Guzzo, C.5
-
18
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, et al. (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314: 1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
-
19
-
-
21044448355
-
Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis
-
Ishizu T, Osoegawa M, Mei FJ, Kikuchi H, Tanaka M, et al. (2005) Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis. Brain 128: 988-1002.
-
(2005)
Brain
, vol.128
, pp. 988-1002
-
-
Ishizu, T.1
Osoegawa, M.2
Mei, F.J.3
Kikuchi, H.4
Tanaka, M.5
-
20
-
-
84859073115
-
Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
-
Leonardi C, Matheson R, Zachariae C, Cameron G, Li L, et al. (2012) Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med 366: 1190-1199.
-
(2012)
N Engl J Med
, vol.366
, pp. 1190-1199
-
-
Leonardi, C.1
Matheson, R.2
Zachariae, C.3
Cameron, G.4
Li, L.5
-
21
-
-
77950535421
-
LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
-
Genovese MC, Van den Bosch F, Roberson SA, Bojin S, Biagini IM, et al. (2010) LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum 62: 929-939.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 929-939
-
-
Genovese, M.C.1
van den Bosch, F.2
Roberson, S.A.3
Bojin, S.4
Biagini, I.M.5
-
22
-
-
77958072084
-
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
-
Hueber W, Patel DD, Dryja T, Wright AM, Koroleva I, et al. (2010) Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2: 52ra72.
-
(2010)
Sci Transl Med
, vol.2
-
-
Hueber, W.1
Patel, D.D.2
Dryja, T.3
Wright, A.M.4
Koroleva, I.5
-
23
-
-
77949897036
-
Importance of cytokines in murine allergic airway disease and human asthma
-
Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M, (2010) Importance of cytokines in murine allergic airway disease and human asthma. J Immunol 184: 1663-1674.
-
(2010)
J Immunol
, vol.184
, pp. 1663-1674
-
-
Finkelman, F.D.1
Hogan, S.P.2
Hershey, G.K.3
Rothenberg, M.E.4
Wills-Karp, M.5
-
24
-
-
33751180809
-
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
-
Bullens DM, Truyen E, Coteur L, Dilissen E, Hellings PW, et al. (2006) IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res 7: 135.
-
(2006)
Respir Res
, vol.7
, pp. 135
-
-
Bullens, D.M.1
Truyen, E.2
Coteur, L.3
Dilissen, E.4
Hellings, P.W.5
-
25
-
-
65349102533
-
Regulation of TH17 cells in the mucosal surfaces
-
Mucida D, Salek-Ardakani S, (2009) Regulation of TH17 cells in the mucosal surfaces. J Allergy Clin Immunol 123: 997-1003.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 997-1003
-
-
Mucida, D.1
Salek-Ardakani, S.2
-
26
-
-
67651162340
-
Immunobiology of asthma
-
Hamid Q, Tulic M, (2009) Immunobiology of asthma. Annu Rev Physiol 71: 489-507.
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 489-507
-
-
Hamid, Q.1
Tulic, M.2
-
27
-
-
33750365602
-
Immunoregulation by targeting T cells in the treatment of allergy and asthma
-
Larche M, (2006) Immunoregulation by targeting T cells in the treatment of allergy and asthma. Curr Opin Immunol 18: 745-750.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 745-750
-
-
Larche, M.1
-
28
-
-
0036310908
-
Non-eosinophilic asthma: importance and possible mechanisms
-
Douwes J, Gibson P, Pekkanen J, Pearce N, (2002) Non-eosinophilic asthma: importance and possible mechanisms. Thorax 57: 643-648.
-
(2002)
Thorax
, vol.57
, pp. 643-648
-
-
Douwes, J.1
Gibson, P.2
Pekkanen, J.3
Pearce, N.4
-
29
-
-
0033954741
-
The relationship between airways inflammation and asthma severity
-
Louis R, Lau LC, Bron AO, Roldaan AC, Radermecker M, et al. (2000) The relationship between airways inflammation and asthma severity. Am J Respir Crit Care Med 161: 9-16.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 9-16
-
-
Louis, R.1
Lau, L.C.2
Bron, A.O.3
Roldaan, A.C.4
Radermecker, M.5
-
30
-
-
0035177659
-
Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma
-
Woodruff PG, Khashayar R, Lazarus SC, Janson S, Avila P, et al. (2001) Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma. J Allergy Clin Immunol 108: 753-758.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 753-758
-
-
Woodruff, P.G.1
Khashayar, R.2
Lazarus, S.C.3
Janson, S.4
Avila, P.5
-
31
-
-
84862776751
-
IL-17A produced by alphabeta T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction
-
Kudo M, Melton AC, Chen C, Engler MB, Huang KE, et al. (2012) IL-17A produced by alphabeta T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nat Med 18: 547-554.
-
(2012)
Nat Med
, vol.18
, pp. 547-554
-
-
Kudo, M.1
Melton, A.C.2
Chen, C.3
Engler, M.B.4
Huang, K.E.5
-
32
-
-
56149097181
-
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice
-
McKinley L, Alcorn JF, Peterson A, Dupont RB, Kapadia S, et al. (2008) TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol 181: 4089-4097.
-
(2008)
J Immunol
, vol.181
, pp. 4089-4097
-
-
McKinley, L.1
Alcorn, J.F.2
Peterson, A.3
Dupont, R.B.4
Kapadia, S.5
-
33
-
-
0037216818
-
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma
-
Hellings PW, Kasran A, Liu Z, Vandekerckhove P, Wuyts A, et al. (2003) Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol 28: 42-50.
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 42-50
-
-
Hellings, P.W.1
Kasran, A.2
Liu, Z.3
Vandekerckhove, P.4
Wuyts, A.5
-
34
-
-
0033557728
-
Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
-
Laan M, Cui ZH, Hoshino H, Lotvall J, Sjostrand M, et al. (1999) Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol 162: 2347-2352.
-
(1999)
J Immunol
, vol.162
, pp. 2347-2352
-
-
Laan, M.1
Cui, Z.H.2
Hoshino, H.3
Lotvall, J.4
Sjostrand, M.5
-
35
-
-
33846456273
-
IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection
-
Wu Q, Martin RJ, Rino JG, Breed R, Torres RM, et al. (2007) IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes Infect 9: 78-86.
-
(2007)
Microbes Infect
, vol.9
, pp. 78-86
-
-
Wu, Q.1
Martin, R.J.2
Rino, J.G.3
Breed, R.4
Torres, R.M.5
-
36
-
-
33751506710
-
Interleukin-17 is a negative regulator of established allergic asthma
-
Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, et al. (2006) Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med 203: 2715-2725.
-
(2006)
J Exp Med
, vol.203
, pp. 2715-2725
-
-
Schnyder-Candrian, S.1
Togbe, D.2
Couillin, I.3
Mercier, I.4
Brombacher, F.5
-
37
-
-
77957098141
-
Resolution of allergic airway inflammation and airway hyperreactivity is mediated by IL-17-producing {gamma}{delta}T cells
-
Murdoch JR, Lloyd CM, (2010) Resolution of allergic airway inflammation and airway hyperreactivity is mediated by IL-17-producing {gamma}{delta}T cells. Am J Respir Crit Care Med 182: 464-476.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 464-476
-
-
Murdoch, J.R.1
Lloyd, C.M.2
-
38
-
-
0035810399
-
Complement. First of two parts
-
Walport MJ, (2001) Complement. First of two parts. N Engl J Med 344: 1058-1066.
-
(2001)
N Engl J Med
, vol.344
, pp. 1058-1066
-
-
Walport, M.J.1
-
39
-
-
0035849176
-
Complement. Second of two parts
-
Walport MJ, (2001) Complement. Second of two parts. N Engl J Med 344: 1140-1144.
-
(2001)
N Engl J Med
, vol.344
, pp. 1140-1144
-
-
Walport, M.J.1
-
40
-
-
77955883153
-
Complement: a key system for immune surveillance and homeostasis
-
Ricklin D, Hajishengallis G, Yang K, Lambris JD, (2010) Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11: 785-797.
-
(2010)
Nat Immunol
, vol.11
, pp. 785-797
-
-
Ricklin, D.1
Hajishengallis, G.2
Yang, K.3
Lambris, J.D.4
-
41
-
-
33745712069
-
The role of complement in danger sensing and transmission
-
Kohl J, (2006) The role of complement in danger sensing and transmission. Immunol Res 34: 157-176.
-
(2006)
Immunol Res
, vol.34
, pp. 157-176
-
-
Kohl, J.1
-
43
-
-
0035253577
-
Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma
-
Drouin SM, Kildsgaard J, Haviland J, Zabner J, Jia HP, et al. (2001) Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma. J Immunol 166: 2025-2032.
-
(2001)
J Immunol
, vol.166
, pp. 2025-2032
-
-
Drouin, S.M.1
Kildsgaard, J.2
Haviland, J.3
Zabner, J.4
Jia, H.P.5
-
44
-
-
0037871469
-
Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells
-
Monsinjon T, Gasque P, Chan P, Ischenko A, Brady JJ, et al. (2003) Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells. FASEB J 17: 1003-1014.
-
(2003)
FASEB J
, vol.17
, pp. 1003-1014
-
-
Monsinjon, T.1
Gasque, P.2
Chan, P.3
Ischenko, A.4
Brady, J.J.5
-
45
-
-
0038264433
-
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1
-
Reca R, Mastellos D, Majka M, Marquez L, Ratajczak J, et al. (2003) Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1. Blood 101: 3784-3793.
-
(2003)
Blood
, vol.101
, pp. 3784-3793
-
-
Reca, R.1
Mastellos, D.2
Majka, M.3
Marquez, L.4
Ratajczak, J.5
-
46
-
-
0034541183
-
Activated human T lymphocytes express a functional C3a receptor
-
Werfel T, Kirchhoff K, Wittmann M, Begemann G, Kapp A, et al. (2000) Activated human T lymphocytes express a functional C3a receptor. J Immunol 165: 6599-6605.
-
(2000)
J Immunol
, vol.165
, pp. 6599-6605
-
-
Werfel, T.1
Kirchhoff, K.2
Wittmann, M.3
Begemann, G.4
Kapp, A.5
-
47
-
-
0030739649
-
The human C3a receptor is expressed on neutrophils and monocytes, but not on B or T lymphocytes
-
Martin U, Bock D, Arseniev L, Tornetta MA, Ames RS, et al. (1997) The human C3a receptor is expressed on neutrophils and monocytes, but not on B or T lymphocytes. J Exp Med 186: 199-207.
-
(1997)
J Exp Med
, vol.186
, pp. 199-207
-
-
Martin, U.1
Bock, D.2
Arseniev, L.3
Tornetta, M.A.4
Ames, R.S.5
-
48
-
-
1842684175
-
Human monocyte-derived dendritic cells are chemoattracted to C3a after up-regulation of the C3a receptor with interferons
-
Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, et al. (2004) Human monocyte-derived dendritic cells are chemoattracted to C3a after up-regulation of the C3a receptor with interferons. Immunology 111: 435-443.
-
(2004)
Immunology
, vol.111
, pp. 435-443
-
-
Gutzmer, R.1
Lisewski, M.2
Zwirner, J.3
Mommert, S.4
Diesel, C.5
-
49
-
-
0035891592
-
Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma
-
Krug N, Tschernig T, Erpenbeck VJ, Hohlfeld JM, Kohl J, (2001) Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma. Am J Respir Crit Care Med 164: 1841-1843.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1841-1843
-
-
Krug, N.1
Tschernig, T.2
Erpenbeck, V.J.3
Hohlfeld, J.M.4
Kohl, J.5
-
50
-
-
0034739041
-
A role for the C3a anaphylatoxin receptor in the effector phase of asthma
-
Humbles AA, Lu B, Nilsson CA, Lilly C, Israel E, et al. (2000) A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature 406: 998-1001.
-
(2000)
Nature
, vol.406
, pp. 998-1001
-
-
Humbles, A.A.1
Lu, B.2
Nilsson, C.A.3
Lilly, C.4
Israel, E.5
-
51
-
-
0026539082
-
ELISA of complement C3a in bronchoalveolar lavage fluid
-
van de Graaf EA, Jansen HM, Bakker MM, Alberts C, Eeftinck Schattenkerk JK, et al. (1992) ELISA of complement C3a in bronchoalveolar lavage fluid. J Immunol Methods 147: 241-250.
-
(1992)
J Immunol Methods
, vol.147
, pp. 241-250
-
-
van de Graaf, E.A.1
Jansen, H.M.2
Bakker, M.M.3
Alberts, C.4
Eeftinck Schattenkerk, J.K.5
-
52
-
-
0037111427
-
Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy
-
Drouin SM, Corry DB, Hollman TJ, Kildsgaard J, Wetsel RA, (2002) Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy. J Immunol 169: 5926-5933.
-
(2002)
J Immunol
, vol.169
, pp. 5926-5933
-
-
Drouin, S.M.1
Corry, D.B.2
Hollman, T.J.3
Kildsgaard, J.4
Wetsel, R.A.5
-
53
-
-
19944428796
-
Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation
-
Baelder R, Fuchs B, Bautsch W, Zwirner J, Kohl J, et al. (2005) Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation. J Immunol 174: 783-789.
-
(2005)
J Immunol
, vol.174
, pp. 783-789
-
-
Baelder, R.1
Fuchs, B.2
Bautsch, W.3
Zwirner, J.4
Kohl, J.5
-
54
-
-
70349320170
-
Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice
-
Mizutani N, Nabe T, Yoshino S, (2009) Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice. J Immunol 183: 4039-4046.
-
(2009)
J Immunol
, vol.183
, pp. 4039-4046
-
-
Mizutani, N.1
Nabe, T.2
Yoshino, S.3
-
55
-
-
77953471537
-
IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis
-
Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, et al. (2010) IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis. J Immunol 184: 6367-6377.
-
(2010)
J Immunol
, vol.184
, pp. 6367-6377
-
-
Lo Re, S.1
Dumoutier, L.2
Couillin, I.3
van Vyve, C.4
Yakoub, Y.5
-
56
-
-
80555126053
-
Invariant NKT cell defects in vitamin D receptor knockout mice prevents experimental lung inflammation
-
Yu S, Zhao J, Cantorna MT, (2011) Invariant NKT cell defects in vitamin D receptor knockout mice prevents experimental lung inflammation. J Immunol 187: 4907-4912.
-
(2011)
J Immunol
, vol.187
, pp. 4907-4912
-
-
Yu, S.1
Zhao, J.2
Cantorna, M.T.3
-
57
-
-
79955778291
-
Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD
-
Eustace A, Smyth LJ, Mitchell L, Williamson K, Plumb J, et al. (2011) Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD. Chest 139: 1089-1100.
-
(2011)
Chest
, vol.139
, pp. 1089-1100
-
-
Eustace, A.1
Smyth, L.J.2
Mitchell, L.3
Williamson, K.4
Plumb, J.5
-
58
-
-
0037111369
-
A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease
-
Kheradmand F, Kiss A, Xu J, Lee SH, Kolattukudy PE, et al. (2002) A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease. J Immunol 169: 5904-5911.
-
(2002)
J Immunol
, vol.169
, pp. 5904-5911
-
-
Kheradmand, F.1
Kiss, A.2
Xu, J.3
Lee, S.H.4
Kolattukudy, P.E.5
-
59
-
-
0346672377
-
Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy
-
Lee SH, Kiss A, Xu J, Qian Y, Bashoura L, et al. (2004) Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy. J Allergy Clin Immunol 113: 72-78.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 72-78
-
-
Lee, S.H.1
Kiss, A.2
Xu, J.3
Qian, Y.4
Bashoura, L.5
-
60
-
-
76949102494
-
Regulation of IL-9 expression by IL-25 signaling
-
Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C, (2010) Regulation of IL-9 expression by IL-25 signaling. Nat Immunol 11: 250-256.
-
(2010)
Nat Immunol
, vol.11
, pp. 250-256
-
-
Angkasekwinai, P.1
Chang, S.H.2
Thapa, M.3
Watarai, H.4
Dong, C.5
-
61
-
-
34447281733
-
Interleukin 25 promotes the initiation of proallergic type 2 responses
-
Angkasekwinai P, Park H, Wang YH, Chang SH, Corry DB, et al. (2007) Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med 204: 1509-1517.
-
(2007)
J Exp Med
, vol.204
, pp. 1509-1517
-
-
Angkasekwinai, P.1
Park, H.2
Wang, Y.H.3
Chang, S.H.4
Corry, D.B.5
-
62
-
-
0034670027
-
Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock
-
Kildsgaard J, Hollmann TJ, Matthews KW, Bian K, Murad F, et al. (2000) Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J Immunol 165: 5406-5409.
-
(2000)
J Immunol
, vol.165
, pp. 5406-5409
-
-
Kildsgaard, J.1
Hollmann, T.J.2
Matthews, K.W.3
Bian, K.4
Murad, F.5
-
63
-
-
20044367482
-
Complementary role of CD4+CD25+ regulatory T cells and TGF-beta in oral tolerance
-
Chung Y, Lee SH, Kim DH, Kang CY, (2005) Complementary role of CD4+CD25+ regulatory T cells and TGF-beta in oral tolerance. J Leukoc Biol 77: 906-913.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 906-913
-
-
Chung, Y.1
Lee, S.H.2
Kim, D.H.3
Kang, C.Y.4
-
64
-
-
42149127675
-
A critical role of costimulation during intrathymic development of invariant NK T cells
-
Chung Y, Nurieva R, Esashi E, Wang YH, Zhou D, et al. (2008) A critical role of costimulation during intrathymic development of invariant NK T cells. J Immunol 180: 2276-2283.
-
(2008)
J Immunol
, vol.180
, pp. 2276-2283
-
-
Chung, Y.1
Nurieva, R.2
Esashi, E.3
Wang, Y.H.4
Zhou, D.5
-
65
-
-
0036774232
-
Preventive and therapeutic effects of oral tolerance in a murine model of asthma
-
Chung Y, Cho J, Chang YS, Cho SH, Kang CY, (2002) Preventive and therapeutic effects of oral tolerance in a murine model of asthma. Immunobiology 206: 408-423.
-
(2002)
Immunobiology
, vol.206
, pp. 408-423
-
-
Chung, Y.1
Cho, J.2
Chang, Y.S.3
Cho, S.H.4
Kang, C.Y.5
-
66
-
-
42049109282
-
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury
-
Sheerin NS, Risley P, Abe K, Tang Z, Wong W, et al. (2008) Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J 22: 1065-1072.
-
(2008)
FASEB J
, vol.22
, pp. 1065-1072
-
-
Sheerin, N.S.1
Risley, P.2
Abe, K.3
Tang, Z.4
Wong, W.5
-
67
-
-
34250179805
-
Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses
-
Dillard P, Wetsel RA, Drouin SM, (2007) Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses. Am J Respir Crit Care Med 175: 1250-1258.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1250-1258
-
-
Dillard, P.1
Wetsel, R.A.2
Drouin, S.M.3
-
68
-
-
0035808261
-
C3A binds to the seven transmembrane anaphylatoxin receptor expressed by epithelial cells and triggers the production of IL-8
-
Monsinjon T, Gasque P, Ischenko A, Fontaine M, (2001) C3A binds to the seven transmembrane anaphylatoxin receptor expressed by epithelial cells and triggers the production of IL-8. FEBS Lett 487: 339-346.
-
(2001)
FEBS Lett
, vol.487
, pp. 339-346
-
-
Monsinjon, T.1
Gasque, P.2
Ischenko, A.3
Fontaine, M.4
-
69
-
-
77954309911
-
Role and mechanism of action of complement in regulating T cell immunity
-
Dunkelberger JR, Song WC, (2010) Role and mechanism of action of complement in regulating T cell immunity. Mol Immunol 47: 2176-2186.
-
(2010)
Mol Immunol
, vol.47
, pp. 2176-2186
-
-
Dunkelberger, J.R.1
Song, W.C.2
-
70
-
-
79952761637
-
Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2
-
Chen Y, Haines CJ, Gutcher I, Hochweller K, Blumenschein WM, et al. (2011) Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2. Immunity 34: 409-421.
-
(2011)
Immunity
, vol.34
, pp. 409-421
-
-
Chen, Y.1
Haines, C.J.2
Gutcher, I.3
Hochweller, K.4
Blumenschein, W.M.5
-
71
-
-
33744984785
-
Th17: an effector CD4 T cell lineage with regulatory T cell ties
-
Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM, (2006) Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24: 677-688.
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
72
-
-
34547116200
-
A new mechanism regulating the initiation of allergic airway inflammation
-
Kiss A, Montes M, Susarla S, Jaensson EA, Drouin SM, et al. (2007) A new mechanism regulating the initiation of allergic airway inflammation. J Allergy Clin Immunol 120: 334-342.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 334-342
-
-
Kiss, A.1
Montes, M.2
Susarla, S.3
Jaensson, E.A.4
Drouin, S.M.5
-
73
-
-
70349320170
-
Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice
-
Mizutani N, Nabe T, Yoshino S, (2009) Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice. Journal of immunology 183: 4039-4046.
-
(2009)
Journal of Immunology
, vol.183
, pp. 4039-4046
-
-
Mizutani, N.1
Nabe, T.2
Yoshino, S.3
-
74
-
-
78149326083
-
A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
-
Wang YH, Voo KS, Liu B, Chen CY, Uygungil B, et al. (2010) A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med 207: 2479-2491.
-
(2010)
J Exp Med
, vol.207
, pp. 2479-2491
-
-
Wang, Y.H.1
Voo, K.S.2
Liu, B.3
Chen, C.Y.4
Uygungil, B.5
-
75
-
-
70349260730
-
Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production
-
Fang C, Zhang X, Miwa T, Song WC, (2009) Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production. Blood 114: 1005-1015.
-
(2009)
Blood
, vol.114
, pp. 1005-1015
-
-
Fang, C.1
Zhang, X.2
Miwa, T.3
Song, W.C.4
-
76
-
-
17644388462
-
Role of C5a in inflammatory responses
-
Guo RF, Ward PA, (2005) Role of C5a in inflammatory responses. Annu Rev Immunol 23: 821-852.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 821-852
-
-
Guo, R.F.1
Ward, P.A.2
-
77
-
-
77953497686
-
Complement drives Th17 cell differentiation and triggers autoimmune arthritis
-
Hashimoto M, Hirota K, Yoshitomi H, Maeda S, Teradaira S, et al. (2010) Complement drives Th17 cell differentiation and triggers autoimmune arthritis. J Exp Med 207: 1135-1143.
-
(2010)
J Exp Med
, vol.207
, pp. 1135-1143
-
-
Hashimoto, M.1
Hirota, K.2
Yoshitomi, H.3
Maeda, S.4
Teradaira, S.5
-
78
-
-
77749285675
-
C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells
-
Weaver DJ Jr, Reis ES, Pandey MK, Kohl G, Harris N, et al. (2010) C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells. Eur J Immunol 40: 710-721.
-
(2010)
Eur J Immunol
, vol.40
, pp. 710-721
-
-
Weaver Jr., D.J.1
Reis, E.S.2
Pandey, M.K.3
Kohl, G.4
Harris, N.5
-
79
-
-
84860902599
-
Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis
-
Bosmann M, Sarma JV, Atefi G, Zetoune FS, Ward PA, (2012) Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 26: 1640-1651.
-
(2012)
FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
, vol.26
, pp. 1640-1651
-
-
Bosmann, M.1
Sarma, J.V.2
Atefi, G.3
Zetoune, F.S.4
Ward, P.A.5
-
80
-
-
84859979283
-
Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells
-
Valdez PA, Vithayathil PJ, Janelsins BM, Shaffer AL, Williamson PR, et al. (2012) Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. Immunity 36: 668-679.
-
(2012)
Immunity
, vol.36
, pp. 668-679
-
-
Valdez, P.A.1
Vithayathil, P.J.2
Janelsins, B.M.3
Shaffer, A.L.4
Williamson, P.R.5
-
81
-
-
0020686610
-
Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77
-
Hartung HP, Bitter-Suermann D, Hadding U, (1983) Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. J Immunol 130: 1345-1349.
-
(1983)
J Immunol
, vol.130
, pp. 1345-1349
-
-
Hartung, H.P.1
Bitter-Suermann, D.2
Hadding, U.3
-
82
-
-
0021186838
-
Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components
-
Hansch GM, Seitz M, Martinotti G, Betz M, Rauterberg EW, et al. (1984) Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. J Immunol 133: 2145-2150.
-
(1984)
J Immunol
, vol.133
, pp. 2145-2150
-
-
Hansch, G.M.1
Seitz, M.2
Martinotti, G.3
Betz, M.4
Rauterberg, E.W.5
-
83
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B, (2006) TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
|